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FAAH Pipeline<br />

64<br />

FAAH blockers are a very new class<br />

of drugs, as currently <strong>the</strong>re are only<br />

two drugs from this group in <strong>the</strong> clinic.<br />

Both are owned by sanofi-aventis,<br />

which began clinical testing in March<br />

2006 (SSR411298) and February<br />

2007 (SSR 101010). No data about<br />

ei<strong>the</strong>r of <strong>the</strong>se trials has been<br />

released to date.<br />

Defined Health analysis<br />

Compound<br />

SSR 101010<br />

SSR411298<br />

KDS 4103<br />

ORG 231295<br />

OL-135<br />

FAAH Inhibitor<br />

JNJ 2883315<br />

JNJ 1661010<br />

RN-A<br />

RN-B<br />

FAAH Inhibitor<br />

Adis R&D Insight<br />

© Defined Health, 2009<br />

Pain Insight Briefing<br />

Developer<br />

sanofi-aventis<br />

sanofi-aventis<br />

Schering-Plough<br />

Schering-Plough<br />

Adolor Corporation<br />

Vernalis<br />

Johnson & Johnson<br />

Johnson & Johnson<br />

Evotec AG<br />

Evotec AG<br />

Infinity/Purdue/Mundipharma<br />

Phase<br />

I<br />

I<br />

Preclinical<br />

Preclinical<br />

Preclinical<br />

Preclinical<br />

Preclinical<br />

Preclinical<br />

Preclinical<br />

Preclinical<br />

Preclinical<br />

Indications<br />

Anxiety disorders, depression<br />

Anxiety disorders, depression<br />

Anxiety, depression, and pain<br />

Anxiety, depression, and pain<br />

Inflammatory pain<br />

Neuropathic pain<br />

Neuropathic pain<br />

Neuropathic pain<br />

Chronic pain<br />

Chronic pain<br />

Neuropathic pain

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