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An Estimated 250 M Suffer From Chronic Pain WW<br />

6<br />

Acute pain and chronic pain differ in <strong>the</strong>ir etiology, pathophysiology and<br />

treatment.<br />

• Acute pain is self-limiting and serves a protective biological function; however, we still want<br />

it minimized.<br />

• Chronic pain (both nociceptive/inflammatory and neuropathic), on <strong>the</strong> o<strong>the</strong>r hand, is itself a<br />

disease process.<br />

Pfizer Analyst and Investor Meeting Oct. 28, 2008<br />

© Defined Health, 2009<br />

Pain Insight Briefing<br />

For several of <strong>the</strong>se chronic<br />

conditions, such as chronic low<br />

back pain (CLBP), fibromyalgia and<br />

neuropathic pain, prevalence<br />

estimates are likely to be significant<br />

undercalls, as treatment specific for<br />

<strong>the</strong>se pain types is ei<strong>the</strong>r nonexistent<br />

or nascent.<br />

= untapped market potential.

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