29.12.2012 Views

2012 aaps annual meeting and Exposition - American Association of ...

2012 aaps annual meeting and Exposition - American Association of ...

2012 aaps annual meeting and Exposition - American Association of ...

SHOW MORE
SHOW LESS

You also want an ePaper? Increase the reach of your titles

YUMPU automatically turns print PDFs into web optimized ePapers that Google loves.

<strong>2012</strong> awards<br />

prOgram<br />

October 14–18, <strong>2012</strong><br />

McCormick Place, Chicago


<strong>2012</strong> <strong>aaps</strong> <strong>annual</strong> <strong>meeting</strong> <strong>and</strong> <strong>Exposition</strong><br />

Sunday, October 14<br />

4:30 pm – 6:30 pm<br />

McCormick Place, Chicago<br />

david Y. mitchell, ph.d.<br />

PreSiding AAPS PreSident<br />

In mEmOrIum<br />

OpEnIng sEssIOn prOgram<br />

The <strong>American</strong><br />

<strong>Association</strong> <strong>of</strong><br />

Pharmaceutical<br />

Scientists (AAPS)<br />

is sad to report the<br />

loss <strong>of</strong> a dear friend<br />

<strong>and</strong> colleague.<br />

AAPS’ fourth<br />

president, James<br />

(Jim) E. Tingstad,<br />

passed away on<br />

November 9, 2011, after a long struggle with<br />

Alzheimer’s disease. Raised in Cook, MN,<br />

<strong>and</strong> Milwaukee, Tingstad served in the U.S.<br />

Army in Korea <strong>and</strong> attended the University<br />

<strong>of</strong> Wisconsin, Madison, where he received<br />

his doctorate in pharmaceutical sciences in<br />

1958. Over the course <strong>of</strong> his life, Tingstad<br />

You are cordially invited to<br />

attend the AAPS Welcome<br />

Reception immediately<br />

following this ceremony. The<br />

reception will take place at the<br />

McCormick Place Convention<br />

Center. Shuttle buses will be<br />

available to transport attendees<br />

to their hotels following the<br />

Opening Session <strong>and</strong> the<br />

Welcome Reception.<br />

held positions at various companies <strong>and</strong><br />

educational institutions including 3M, Abbott<br />

Laboratories, <strong>and</strong> the University <strong>of</strong> California<br />

San Francisco School <strong>of</strong> Pharmacy.<br />

Tingstad’s term as AAPS president was<br />

characterized by growth. The association<br />

saw a huge increase in membership, staff<br />

size, <strong>and</strong> <strong>of</strong>fice facilities during his tenure,<br />

as well as the number <strong>of</strong> sections <strong>and</strong><br />

growth in assets <strong>and</strong> financial security.<br />

Tingstad is survived by his wife Phyllis,<br />

four children, <strong>and</strong> a host <strong>of</strong> gr<strong>and</strong>children,<br />

great-gr<strong>and</strong>children, <strong>and</strong> other family<br />

<strong>and</strong> friends. AAPS remembers Tingstad<br />

<strong>and</strong> will forever remember his contributions<br />

to the association.<br />

<strong>2012</strong> AAPS Annual Meeting <strong>and</strong> <strong>Exposition</strong> 1


OpEnIng sEssIOn prOgram<br />

In mEmOrIum (continued)<br />

dean Emeritus<br />

Joseph V.<br />

swintosky, a<br />

legendary educator<br />

<strong>and</strong> scientist<br />

who helped lead<br />

the University <strong>of</strong><br />

Kentucky College<br />

<strong>of</strong> Pharmacy<br />

to national <strong>and</strong><br />

international<br />

prominence during his tenure as dean from<br />

1967 to 1987, passed away on September 14,<br />

<strong>2012</strong>. He was 90 years old.<br />

Dr. Swintosky, a native <strong>of</strong> Kewaunee County,<br />

Wisconsin, received his bachelor <strong>of</strong> science<br />

degree <strong>and</strong> Ph.D. in pharmacy from the<br />

University <strong>of</strong> Wisconsin. An accomplished<br />

educator, product formulation scientist,<br />

<strong>and</strong> recipient <strong>of</strong> numerous national honors,<br />

a.J.m. (Ton) Hoek<br />

was born in The<br />

Hague, in 1955 <strong>and</strong><br />

studied Pharmacy at<br />

the State University<br />

<strong>of</strong> Leiden in the<br />

Netherl<strong>and</strong>s.<br />

He obtained his<br />

Master <strong>of</strong> Science<br />

degree in 1983 <strong>and</strong><br />

graduated as a pharmacist in 1984. He had<br />

training periods in both the pharmaceutical<br />

practice <strong>and</strong> the hospital pharmacy.<br />

After university Ton Hoek joined the<br />

pharmaceutical industry <strong>and</strong> worked at<br />

several management positions both in R&D<br />

as well as in marketing.<br />

From 1999, Ton Hoek was the General<br />

Secretary <strong>and</strong> Chief Executive Officer <strong>of</strong> FIP,<br />

the International Pharmaceutical Federation.<br />

The FIP is the global federation <strong>of</strong> 127<br />

national organizations <strong>of</strong> pharmacists <strong>and</strong><br />

pharmaceutical scientists, with its mission<br />

to improve global health by: advancing<br />

pharmacy practice <strong>and</strong> science, to enable<br />

2<br />

Awards Program<br />

Dr. Swintosky is probably best known for<br />

his innovative work to transform pharmacy<br />

education <strong>and</strong> the pharmacy pr<strong>of</strong>ession<br />

while at UK.<br />

On January 1, 1967, Dr. Swintosky became<br />

the fourth Dean <strong>of</strong> the UK College <strong>of</strong><br />

Pharmacy <strong>and</strong> created the master’s <strong>and</strong><br />

Ph.D. graduate program, a move that<br />

cemented UK as a national leader in<br />

graduate education <strong>and</strong> pharmaceutical<br />

research. His impact on pharmacy<br />

continues today through the achievements<br />

<strong>of</strong> former faculty <strong>and</strong> graduates who now<br />

are national <strong>and</strong> international leaders,<br />

including at least 10 deans at other colleges.<br />

Dr. Swintosky was a Founder <strong>of</strong> AAPS. He<br />

leaves behind his wife Dorothy, nine sons<br />

<strong>and</strong> one daughter.<br />

better discovery, development, access to<br />

<strong>and</strong> safe use <strong>of</strong> appropriate, cost-effective,<br />

<strong>and</strong> quality medicines worldwide.<br />

Together with his counterparts from<br />

the World Medical <strong>Association</strong> <strong>and</strong> the<br />

International Council <strong>of</strong> Nurses, Hoek has<br />

set up the World Health Pr<strong>of</strong>essions Alliance<br />

(WHPA), a strategic alliance between the<br />

global health pr<strong>of</strong>essional associations<br />

representing physicians, nurses, dentists<br />

<strong>and</strong> pharmacists.<br />

In <strong>2012</strong> Hoek was awarded an Officer in<br />

the Orange-Nassau, a Royal declaration<br />

bestowed by the Queen <strong>of</strong> the Netherl<strong>and</strong>s.<br />

During the awards ceremony for this<br />

prestigious designation he was also<br />

recognised with an honorary resolution<br />

from the <strong>American</strong> Pharmacists <strong>Association</strong><br />

(APhA) citing his active dedication to<br />

pharmacy <strong>and</strong> a joint congratulatory letter<br />

from the APhA, the <strong>American</strong> <strong>Association</strong><br />

<strong>of</strong> Colleges <strong>of</strong> Pharmacy (AACP), the<br />

<strong>American</strong> <strong>Association</strong> <strong>of</strong> Pharmaceutical<br />

Scientists (AAPS) <strong>and</strong> the <strong>American</strong> Society<br />

<strong>of</strong> Health-Systems Pharmacists (ASHP).


<strong>aaps</strong> <strong>2012</strong> ExEcuTIVE cOuncIl<br />

david Y. mitchell, ph.d.<br />

PreSident<br />

philip r. mayer, ph.d.<br />

iMMediAte PASt PreSident<br />

anthony J. destefano, ph.d.<br />

PreSident-eleCt<br />

wayne r. gombotz, ph.d.<br />

treASurer<br />

marilyn E. morris, ph.d. (<strong>2012</strong>)<br />

MeMber-At-lArge<br />

James E. polli, ph.d. (2013)<br />

MeMber-At-lArge<br />

raman Venkataramanan, ph.d. (2013)<br />

MeMber-At-lArge<br />

dannette K. doolittle, ph.d. (2014)<br />

MeMber-At-lArge<br />

russell s. weiner, ph.d. (2014)<br />

MeMber-At-lArge<br />

<strong>2012</strong> AAPS Annual Meeting <strong>and</strong> <strong>Exposition</strong> 3


OpEnIng sEssIOn prOgram<br />

wElcOmIng rEmarKs<br />

John lisack, Jr., caE<br />

exeCutive direCtOr<br />

4<br />

Awards Program<br />

david Y. mitchell, ph.d.<br />

AAPS PreSident<br />

prEsEnTaTIOn <strong>and</strong> rEcOgnITIOn Of all awards<br />

david Y. mitchell, ph.d. leslie Z. Benet, ph.d.<br />

AAPS PreSident univerSity Of CAlifOrniA


spEcIal rEcOgnITIOns<br />

IpEc Excipient graduate<br />

student awards<br />

xi Han<br />

new JerSey inStitute Of teChnOlOgy<br />

grace Ilevbare<br />

Purdue univerSity<br />

sumit Kumar<br />

univerSity Of COnneCtiCut<br />

Ting wang<br />

univerSity Of MArylAnd, bAltiMOre<br />

amit wani<br />

wAyne StAte univerSity<br />

phrma pre doctoral fellowships<br />

in the pharmaceutics<br />

sweta modi<br />

univerSity Of KentuCKy<br />

poonam sheth<br />

univerSity Of ArizOnA<br />

matthew Herpin<br />

univerSity Of texAS At AuStin<br />

phrma research starter grants<br />

in pharmaceutics<br />

Oleh Taratula, ph.d.<br />

OregOn StAte univerSity<br />

afpE minority pre-doctoral fellows<br />

in pharmaceutical science<br />

sophia n. Ononye<br />

univerSity Of COnneCtiCut<br />

award rEcIpIEnTs<br />

<strong>aaps</strong>-afpE pre-doctoral fellows<br />

in the pharmaceutical sciences<br />

Vaishali l. chudasama<br />

univerSity At buffAlO, Suny<br />

caroline a. larregieu<br />

univerSity Of CAlifOrniA, SAn frAnCiSCO<br />

afpE pre-doctoral fellows in clinical<br />

pharmaceutical sciences<br />

daniel J. crona<br />

univerSity Of nOrth CArOlinA<br />

melanie r. nicol<br />

univerSity Of nOrth CArOlinA<br />

<strong>aaps</strong> graduate student symposium<br />

in analysis & pharmaceutical Quality<br />

SPOnSOred by u.S. Pharmacopeia<br />

<strong>and</strong> wolfe labs<br />

McCormick Place Convention Center<br />

room w190A<br />

tuesday, October 16, <strong>2012</strong><br />

8:30 am – 11:00 am<br />

cary mcginnis<br />

univerSity Of geOrgiA<br />

Quantification <strong>and</strong> Characterization<br />

<strong>of</strong> siRNA <strong>and</strong> its Metabolites in<br />

Biological Matrices<br />

<strong>2012</strong> AAPS Annual Meeting <strong>and</strong> <strong>Exposition</strong> 5


award recipients<br />

Khushboo Bakul Kothari<br />

univerSity Of MinneSOtA<br />

Investigating the Role <strong>of</strong> Polymer<br />

Concentration on the Physical Stability <strong>of</strong><br />

Nifedipine-PVP Solid Dispersions<br />

lindsay anne wegiel<br />

Purdue univerSity<br />

Assessment <strong>of</strong> Molecular Drug-polymer<br />

Interactions by Mid-infrared Spectroscopy<br />

as a Polymer Selection Tool for Formulating<br />

Amorphous Solid Dispersions with Optimal<br />

Physical Stability<br />

poonam r. delvadia<br />

virginiA COMMOnweAlth univerSity<br />

High Performance Liquid Chromatographic<br />

Method <strong>and</strong> Selectivity Investigation for the<br />

Analysis <strong>of</strong> Nicotine in Biorelevant Release/<br />

Permeation Studies <strong>of</strong> Smokeless Tobacco<br />

6<br />

Awards Program<br />

<strong>aaps</strong> graduate student symposium<br />

in Biotechnology<br />

SPOnSOred by Pfizer global research<br />

<strong>and</strong> development<br />

McCormick Place Convention Center<br />

room w190b<br />

tuesday, October 16, <strong>2012</strong><br />

8:30 am – 11:00 am<br />

david woessner<br />

univerSity Of utAh<br />

Synthetically Lethal Combinations for CML<br />

Therapy—Disrupting Dimerization <strong>of</strong> Bcr-Abl<br />

<strong>and</strong> Secondary Leukemia Specific Pathways<br />

Jin Huk choi<br />

the univerSity Of texAS At AuStin<br />

Modeling Pre-existing Immunity to<br />

Adenovirus as a Method to Identify Novel<br />

Formulations for a Protective Ebola Vaccine<br />

mamta Kapoor<br />

univerSity Of COnneCtiCut<br />

Elucidation <strong>of</strong> Cellular Uptake Mechanism <strong>of</strong><br />

Novel Ternary Anionic-siRNA Lipoplexes


puneet Tyagi<br />

univerSity Of COlOrAdO<br />

A Highly Potent, Choroid-targeted,<br />

Transferrin-tumstatin Fusion Protein<br />

<strong>and</strong> an In Situ Forming Slow-release<br />

Hydrogel for the Treatment <strong>of</strong> Choroidal<br />

Neovascularization<br />

<strong>aaps</strong> graduate student symposium<br />

in drug discovery <strong>and</strong> development<br />

Interface<br />

SPOnSOred by Allergan, wolfe laboratories,<br />

<strong>and</strong> bristol-Myers Squibb Company<br />

McCormick Place Convention Center<br />

room w185<br />

tuesday, October 16, <strong>2012</strong><br />

8:30 am – 11:00 am<br />

Yumna shabaik<br />

univerSity Of SOuthern CAlifOrniA<br />

Mechanistic Evaluation <strong>of</strong> a Mitochondrialtargeted<br />

Small Molecule as a Novel<br />

Treatment for Pancreatic Cancer<br />

sashikanth Banappagari<br />

the univerSity Of lOuiSiAnA At MOnrOe<br />

Modulation <strong>of</strong> EGF-receptors Signaling by<br />

Small Peptidomimetics <strong>and</strong> its Implications in<br />

Breast Cancer Progression<br />

award recipients<br />

lu xu<br />

univerSity Of the PACifiC<br />

Molecular Docking, Synthesis <strong>of</strong> Novel<br />

Quinazolin Analogues as Inhibitors <strong>of</strong><br />

Transcription Factors NF-kappaB Activation<br />

<strong>and</strong> their Anti-cancer Activities<br />

lakshmi prasanna Kolluru<br />

MerCer univerSity<br />

Design <strong>and</strong> Development <strong>of</strong> Albumin Based<br />

Theragnostic Nanoparticles for Tumor<br />

Targeted Drug Delivery<br />

<strong>aaps</strong> graduate student symposium in<br />

formulation design <strong>and</strong> development<br />

SPOnSOred by bristol-Myers<br />

Squibb Company<br />

McCormick Place Convention Center<br />

room w196<br />

tuesday, October 16, <strong>2012</strong><br />

8:30 am – 12:00 pm<br />

apurva r. patel<br />

flOridA A&M univerSity<br />

Theranostic Tumor Homing Pegylated<br />

Nanocarrier Drug Delivery System for<br />

Treatment <strong>of</strong> Cancer<br />

<strong>2012</strong> AAPS Annual Meeting <strong>and</strong> <strong>Exposition</strong> 7


award recipients<br />

grace a. Ilevbare<br />

Purdue univerSity<br />

Underst<strong>and</strong>ing Polymer Properties Important<br />

for Crystal Growth Inhibition—Impact <strong>of</strong><br />

Chemically Diverse Polymers on Solution<br />

Crystal Growth <strong>of</strong> Ritonavir<br />

Jiban Jyoti p<strong>and</strong>a<br />

f.M. univerSity, OriSSA, indiA<br />

Self-assembled Dipeptide Nanotubes,<br />

Nanovesicles <strong>and</strong> Nanogels: Potential<br />

Vehicles for Targeted Tumor Drug Delivery<br />

<strong>aaps</strong> graduate student symposium in<br />

manufacturing science <strong>and</strong> Engineering<br />

SPOnSOred by bristol-Myers<br />

Squibb Company<br />

McCormick Place Convention Center<br />

room w196<br />

tuesday, October 16, <strong>2012</strong><br />

8:30 am – 12:00 pm<br />

Ekneet Kaur sahni<br />

univerSity Of COnneCtiCut<br />

Contact Drying in an Agitated Filter-Dryer:<br />

Experiments <strong>and</strong> Simulations<br />

8<br />

Awards Program<br />

<strong>aaps</strong> graduate student symposium<br />

in physical pharmacy <strong>and</strong><br />

Biopharmaceutics<br />

SPOnSOred by bristol-Myers<br />

Squibb Company<br />

McCormick Place Convention Center<br />

room w196<br />

tuesday, October 16, <strong>2012</strong><br />

8:30 am – 12:00 pm<br />

caleb Brian<br />

univerSity Of wiSCOnSin, MAdiSOn<br />

Surface Diffusion <strong>of</strong> the Organic<br />

Glass Nifedipine<br />

sunny Bhardwaj<br />

univerSity Of MinneSOtA<br />

Molecular Mobility as an Effective Predictor<br />

<strong>of</strong> the Physical Stability <strong>of</strong> Amorphous State<br />

<strong>aaps</strong> graduate student symposium in<br />

pharmacokinetics, pharmacodynamics,<br />

<strong>and</strong> drug metabolism <strong>and</strong> clinical<br />

pharmacology <strong>and</strong> Translational<br />

research<br />

SPOnSOred by eli lilly <strong>and</strong> Company<br />

McCormick Place Convention Center<br />

room w184<br />

tuesday, October 16, <strong>2012</strong><br />

8:30 am – 12:00 pm


ajendra s. Kadam<br />

univerSity Of COlOrAdO<br />

Expression <strong>and</strong> Activity <strong>of</strong> Drug Transporters<br />

in Human Ocular Barriers <strong>and</strong> Disease<br />

Related Changes: Implications for<br />

Transporter Guided Retinal Drug Delivery<br />

nimita dave<br />

univerSity Of CinCinnAti<br />

Brain/Brain Tumor Pharmacokinetics <strong>and</strong><br />

Pharmacodynamics <strong>of</strong> Letrozole<br />

rachel J. Eclov<br />

univerSity Of CAlifOrniA, SAn frAnCiSCO<br />

In Vivo Characterization <strong>of</strong> ABCG2 Enhancers<br />

Bridget morse<br />

univerSity At buffAlO, Suny<br />

Effect <strong>of</strong> Monocarboxylate Transporter<br />

Inhibition on the Oral Toxicokinetics/<br />

Toxicodynamics <strong>of</strong> γ-hydroxybutyrate (GHB)<br />

<strong>and</strong> γ-butyrolactone (GBL)<br />

award recipients<br />

ramola sane<br />

univerSity Of MinneSOtA<br />

Application <strong>of</strong> a Novel Microemulsion<br />

Formulation <strong>of</strong> Elacridar to Improve Drug<br />

Distribution into the Brain for Therapy <strong>of</strong><br />

Glioblastoma<br />

Hoi Kei lon<br />

univerSity At buffAlO, Suny<br />

Modeling Effects <strong>of</strong> Dexamethasone on<br />

Disease Progression <strong>of</strong> Bone Mineral Density<br />

in Collagen-induced Arthritic Rats<br />

<strong>aaps</strong> Outst<strong>and</strong>ing graduate student<br />

research award in pharmaceutical<br />

Technologies<br />

SPOnSOred by Covidien<br />

Qi (Tony) Zhou<br />

MOnASh univerSity, AuStrAliA<br />

Effect <strong>of</strong> Surface Coating with Magnesium<br />

Stearate via Mechanical Dry Powder<br />

Coating Approach on the Aerosol<br />

Performance <strong>of</strong> Micronized Drug Powders<br />

from Dry Powder Inhalers<br />

<strong>2012</strong> AAPS Annual Meeting <strong>and</strong> <strong>Exposition</strong> 9


award recipients<br />

mentor: david a V morton, ph.d.<br />

MOnASh univerSity, AuStrAliA<br />

<strong>aaps</strong> lipid-based drug delivery<br />

graduate student award<br />

SPOnSOred by gattefossé Corporation<br />

McCormick Place Convention Center<br />

room w186<br />

Monday, October 15, <strong>2012</strong><br />

12:15 pm – 1:15 pm<br />

Yan Yan Yeap<br />

MOnASh univerSity, AuStrAliA<br />

<strong>aaps</strong> graduate student award<br />

in Quality by design <strong>and</strong> product<br />

performance<br />

SPOnSOred by Quality by design <strong>and</strong><br />

Product Performance focus group<br />

McCormick Place Convention Center<br />

room w178<br />

Monday, October 15, <strong>2012</strong><br />

4:30 pm – 5:30 pm<br />

rishi Kapil<br />

PAnJAb univerSity (uiPS), indiA<br />

10<br />

Awards Program<br />

<strong>aaps</strong> Ocular drug delivery &<br />

disposition focus group graduate<br />

student poster award<br />

SPOnSOred by bausch <strong>and</strong> lomb<br />

McCormick Place Convention Center<br />

room w185<br />

Monday, October 15, <strong>2012</strong><br />

12:15 pm – 1:15 pm<br />

megha Barot<br />

univerSity Of MiSSOuri, KAnSAS City<br />

<strong>aaps</strong> postdoctoral fellow award<br />

SPOnSOred by Abbott laboratories<br />

<strong>and</strong> Merck<br />

The AAPS Postdoctoral Fellow Award<br />

is given <strong>annual</strong>ly to individuals who<br />

demonstrated excellence in his/her research<br />

work during a postdoctoral training period<br />

<strong>and</strong> shows exceptional promise in future<br />

contributions to pharmaceutical sciences.<br />

courtney sloan, ph.d.<br />

univerSity Of illinOiS At urbAnA-ChAMPAign<br />

Dr. Sloan received her Ph.D. in<br />

Pharmaceutical Chemistry from the<br />

University <strong>of</strong> Kansas under the guidance <strong>of</strong><br />

Dr. Susan Lunte in 2011. While in graduate<br />

school, Dr. Sloan developed analytical<br />

methods for characterizing the metabolism<br />

<strong>of</strong> neuropeptides involved in pain signaling,<br />

neurotoxicity, <strong>and</strong> addiction. Additionally,<br />

she investigated the transport <strong>of</strong> peptide<br />

metabolites at the blood-brain barrier.<br />

utilizing bovine brain microvessel endothelial<br />

cells. Currently at the University <strong>of</strong> Illinois at


Urbana-Champaign (UIUC) she is working<br />

in Dr. Ryan Bailey’s group in a collaborative<br />

effort with Dr. Stephen Sligar’s group,<br />

also at UIUC. Pr<strong>of</strong>essor Bailey’s group has<br />

extensively developed silicon photonics as<br />

an analytical tool to investigate molecular<br />

binding events <strong>and</strong> kinetics with soluble<br />

biomolecules such as DNA <strong>and</strong> antibodies.<br />

Dr. Sloan is demonstrating the utility <strong>of</strong> the<br />

optical microring resonator platform for<br />

studying interactions between membranebound<br />

proteins <strong>and</strong> soluble lig<strong>and</strong>s,<br />

utilizing nanodiscs to solubilize membrane<br />

proteins <strong>and</strong> maintain their structure in a<br />

native-like lipid bilayer. Microrings provide<br />

a highly multiplexed analysis platform<br />

for characterizing these receptor-lig<strong>and</strong><br />

interactions. Dr. Sloan hopes to develop<br />

the platform to investigate the role <strong>of</strong> G<br />

protein coupled receptors (GPCRs) as<br />

pharmaceutical targets <strong>and</strong> monitor G<br />

protein coupling as indicators for potential<br />

<strong>of</strong>f-target drug effects.<br />

sumith a. Kulartne, ph.d.<br />

the SCriPPS reSeArCh inStitute<br />

Dr. Kulartne is the Vice President <strong>of</strong><br />

Research & Development, On Target<br />

Laboratories, LLC, West Lafayette, IN (March<br />

<strong>2012</strong>– present). Under his guidance, On<br />

Target is developing targeted-Near Infra<br />

Red (NIR) imaging agents that detect<br />

tumor margins during surgery for cancers<br />

<strong>and</strong> biologics for inflammatory diseases.<br />

On Target is conducting multiple clinical<br />

trials at Mayo clinics, UPenn, IU Medical<br />

School for cancers such as ovarian, lung,<br />

prostate, <strong>and</strong> kidney. Dr. Kularatne pursued<br />

his postdoctoral studies in biomedicines<br />

to target metastatic cancers, cancer stem<br />

cells, acute myeloid leukemia, <strong>and</strong> ovarian<br />

cancer using anti-CXCR4, IL3, <strong>and</strong> bispecific<br />

antibodies with Dr. Peter G. Schultz, The<br />

Scripps Research Institute, La Jolla, CA<br />

(Dec 2009–Feb <strong>2012</strong>). He earned his<br />

award recipients<br />

Ph.D. in organic/medicinal chemistry from<br />

Purdue University (Dec 2005-Dec 2009),<br />

conducting research under the guidance<br />

<strong>of</strong> Ralph C. Corley Distinguished Pr<strong>of</strong>essor<br />

Philip S. Low. During his doctoral studies,<br />

Dr. Kularatne has developed PSMA-targeted<br />

SPECT, PET, <strong>and</strong> optical imaging <strong>and</strong><br />

therapeutic agents for prostate cancer.<br />

He has also developed folate receptortargeted<br />

PET imaging <strong>and</strong> therapeutic.<br />

PSMA-targeted SPECT imaging agent that<br />

he developed is currently evaluating in<br />

Phase I clinical trials at IU Medical School<br />

<strong>and</strong> PSMA-targeted therapeutic agents are<br />

under clinical development at Endocyte Inc,<br />

West Lafayette, IN.<br />

Innovation in nanotechnology award<br />

SPOnSOred by hospira<br />

McCormick Place Convention Center<br />

room w190b<br />

tuesday, October 16, <strong>2012</strong><br />

4:30 pm – 5:30 pm<br />

This award is intended to recognize <strong>and</strong><br />

promote the achievement <strong>of</strong> an individual<br />

that demonstrates innovation in the area<br />

<strong>of</strong> nanotechnology as applied to drug <strong>and</strong><br />

device development.<br />

arun Kumar upadhyay, ph.d.<br />

univerSity Of COlOrAdO AnSChutz<br />

MediCAl CAMPuS<br />

Dr. Upadhyay has developed protein,<br />

polymer, <strong>and</strong> virus based nanosystems<br />

for enhanced <strong>and</strong>/or sustained delivery <strong>of</strong><br />

therapeutic agents including small molecule<br />

drugs, peptides, <strong>and</strong> proteins. He also<br />

elucidated the mechanisms <strong>of</strong> inclusion<br />

body formation <strong>and</strong> developed approaches<br />

for efficient purification <strong>of</strong> protein drugs.<br />

His long term goals include development <strong>of</strong><br />

new drugs <strong>and</strong> delivery systems for treating<br />

retinal degenerative diseases.<br />

<strong>2012</strong> AAPS Annual Meeting <strong>and</strong> <strong>Exposition</strong> 11


award recipients<br />

Outst<strong>and</strong>ing Educator award<br />

SPOnSOred by biogen idec<br />

The AAPS Outst<strong>and</strong>ing Educator Award<br />

recognizes excellence in education in the<br />

technologies related to pharmaceuticals.<br />

John l. neumeyer, ph.d.<br />

hArvArd MediCAl SChOOl/MCleAn hOSPitAl/<br />

AdArC<br />

Dr. Neumeyer, Matthews Distinguished<br />

Pr<strong>of</strong>essor <strong>of</strong> Medicinal Chemistry (Emeritus)<br />

at Northeastern University, has been<br />

designing <strong>and</strong> synthesizing molecules for<br />

mapping <strong>and</strong> studying dopamine receptors<br />

in the brain. Parkinson’s disease (PD) is<br />

caused by the degeneration <strong>of</strong> a set <strong>of</strong><br />

neurons in the brain that use dopamine as a<br />

neurotransmitter. By modifying the structure<br />

<strong>of</strong> apomorphine, a dopamine receptor<br />

agonist, <strong>and</strong> related aporphines, chemists,<br />

pharmacologists <strong>and</strong> molecular biologists<br />

could infer the 3D arrangement <strong>of</strong> amino<br />

acids at the dopamine-binding site. On the<br />

other h<strong>and</strong>, chemical analogs related to<br />

cocaine as well as cocaine itself, are known<br />

to inhibit dopamine uptake by binding to<br />

cocaine receptor sites. Thus, suitably labeled<br />

cocaine analogs could be used as probes to<br />

investigate the neurochemical mechanism<br />

<strong>of</strong> Parkinson’s disease <strong>and</strong> other disorders<br />

involving dopamine neurotransmitters.<br />

This type <strong>of</strong> thinking led Neumeyer <strong>and</strong> his<br />

co-workers to synthesize a new radiotracer<br />

[¬123I]-¬¬CIT. This tracer can be used<br />

in single-photon emission computed<br />

tomography (SPECT) imaging to pinpoint<br />

sites where dopamine is taken up. Similarly,<br />

the imaging technique known as positron<br />

emission tomography (PET) requires<br />

positron-emitting nuclides such as 18F or 11C.<br />

The radiotracer [¬123I]-FP¬CIT (i<strong>of</strong>lupane,<br />

DATscan ® ) is now a commercially available<br />

imaging agent used for the early diagnosis<br />

<strong>of</strong> PD or to monitor the progression <strong>of</strong> PD<br />

in patients.<br />

12<br />

Awards Program<br />

Dr. Neumeyer has trained over 60 graduate<br />

students <strong>and</strong> post-doctoral fellows in the<br />

pharmaceutical sciences at Northeastern<br />

University <strong>and</strong> continues to train postdoctoral<br />

fellows as Director <strong>of</strong> the Medicinal<br />

Chemistry Program at McLean Hospital,<br />

Harvard Medical School.<br />

new Investigator grant in<br />

pharmaceutics <strong>and</strong> the<br />

pharmaceutical Technologies<br />

SPOnSOred by Pfizer global research<br />

<strong>and</strong> development<br />

The AAPS New Investigator Grant in<br />

Pharmaceutics <strong>and</strong> the Pharmaceutical<br />

Technologies is a one-time grant <strong>of</strong> $25,000<br />

to be used to support the research efforts<br />

<strong>of</strong> an individual actively engaged in training<br />

graduate students <strong>and</strong> carrying out the basic<br />

research in pharmaceutics, drug delivery<br />

<strong>and</strong>/or the pharmaceutical technologies.<br />

seungpyo Hong, ph.d.<br />

univerSity Of illinOiS At ChiCAgO<br />

Dr. Hong is Assistant Pr<strong>of</strong>essor in the<br />

Department <strong>of</strong> Biopharmaceutical Sciences<br />

at the University <strong>of</strong> Illinois at Chicago. He<br />

received his B.S. <strong>and</strong> M.S. degrees from<br />

Polymer Engineering at Hanyang University,<br />

Seoul, Korea in 1999 <strong>and</strong> 2011, respectively.<br />

In 2006, he graduated with his Ph.D. in<br />

Macromolecular Science <strong>and</strong> Engineering at<br />

the University <strong>of</strong> Michigan (advisors: Pr<strong>of</strong>s.<br />

Mark Banaszak Holl <strong>and</strong> James Baker, Jr.)<br />

before he joined Pr<strong>of</strong>. Robert Langer’s lab<br />

at MIT for his postdoctoral training. Since<br />

2008, he has established an independent<br />

research program under the overall theme<br />

<strong>of</strong> “Biomimetic Nanotechnology”, focusing<br />

on three major areas: 1) Nanocarrier systems<br />

for targeted delivery <strong>of</strong> therapeutics<br />

using biomimetic approaches; 2) Topical,<br />

transdermal delivery systems for breast<br />

cancer prevention using nanoparticle-drug


combinations; <strong>and</strong> 3) Biomimetic micr<strong>of</strong>luidic<br />

chips for effective separation <strong>of</strong> circulating<br />

tumor cells. He has published over 35 peerreviewed<br />

articles that have been cited a<br />

combined total <strong>of</strong> over 2,200 times, three<br />

book chapters, <strong>and</strong> nine patents (pending or<br />

awarded) while presenting 33 invited talks<br />

<strong>and</strong> over 80 conference proceedings.<br />

<strong>aaps</strong> community service award<br />

SPOnSOred by the university <strong>of</strong> Colorado/<br />

Center for Pharmaceutical biotechnology<br />

The AAPS Community Service Award is<br />

intended to recognize an AAPS member<br />

for the personal effort that he/she created<br />

<strong>and</strong> managed, preferably as a volunteer <strong>and</strong><br />

not part <strong>of</strong> duties in a paid position, for a<br />

sustained community service effort.<br />

Joseph w. polli, ph.d.<br />

glAxOSMithKline, inC.<br />

Dr. Joseph Polli received the AAPS<br />

Community Service Award for service to Cub<br />

Scout Pack 152, Boy Scout Troop 152 <strong>and</strong><br />

the Crosswinds District <strong>of</strong> the Boys Scouts<br />

<strong>of</strong> America located in Cary, North Carolina.<br />

Over the past 14 years, he has contributed<br />

to the skills <strong>and</strong> leadership development<br />

<strong>of</strong> more than one hundred young men,<br />

provided organizational leadership to the<br />

BSA, developed the high adventure outdoor<br />

camping program, <strong>and</strong> has donated financial<br />

support. One highlight <strong>of</strong> Dr. Polli’s service<br />

includes founding <strong>and</strong> chartering Troop 152<br />

with 6 scouts in 2003. Twenty-five scouts<br />

have since obtained the rank <strong>of</strong> Eagle. Dr.<br />

Polli has held multiple leadership positions,<br />

including being the founding Committee<br />

Chair <strong>of</strong> Troop 152, Charter Organizational<br />

Representative, Assistant Scoutmaster,<br />

Secretary/Treasurer <strong>and</strong> District Eagle<br />

Board <strong>of</strong> Review Member. In addition, Joe<br />

is an avid camper who challenges scouts<br />

to go beyond what they believe they are<br />

capable <strong>of</strong> achieving. Outside <strong>of</strong> scouting,<br />

award recipients<br />

Dr. Polli is an internationally recognized<br />

researcher in membrane transporters <strong>and</strong><br />

drug development. His main research<br />

interests include membrane transporters that<br />

influence drug disposition, prediction <strong>of</strong> drug<br />

interactions, <strong>and</strong> processes to enhance the<br />

development <strong>of</strong> drug c<strong>and</strong>idates.<br />

The IpEc foundation ralph shangraw<br />

memorial award<br />

The Ralph Shangraw Memorial Award is<br />

to be awarded to any person who has<br />

provided outst<strong>and</strong>ing research contributions<br />

in the study <strong>of</strong> excipients or excipientrelated<br />

technology over a number <strong>of</strong> years,<br />

including an underst<strong>and</strong>ing <strong>of</strong> the basic<br />

science underlying excipient functionality<br />

<strong>and</strong> the development <strong>of</strong> new excipients or<br />

noveluse <strong>of</strong> existing excipients.<br />

Hans E. Junginger, ph.d. (retired)<br />

MArbury, gerMAny<br />

Pr<strong>of</strong>essor Junginger received his Ph.D. at<br />

the University <strong>of</strong> Saarl<strong>and</strong> (Germany) in 1971.<br />

He was a Pr<strong>of</strong>essor <strong>of</strong> pharmaceutics <strong>and</strong><br />

the Head <strong>of</strong> the Division <strong>of</strong> Pharmaceutical<br />

Technology at the Leiden/Amsterdam Center<br />

for Drug Research, Leiden University, The<br />

Netherl<strong>and</strong>s, until February 1, 2004 when he<br />

went with early retirement. His main research<br />

areas include the development <strong>of</strong> novelcontrolled<br />

drug delivery systems peroral<br />

routes, utilizing new (bioadhesive) polymers<br />

for the nasal, pulmonary <strong>and</strong> oral route for<br />

peptides, proteins, <strong>and</strong> (DNA) vaccines.<br />

He also was strongly involved in (trans)<br />

dermal drug research <strong>and</strong> has developed<br />

more than 100 cosmetics products based<br />

on aloe vera. He has received several major<br />

awards including the <strong>American</strong> <strong>Association</strong> <strong>of</strong><br />

Pharmaceutical Scientists (AAPS) Dr. Rainer<br />

H<strong>of</strong>fman Product through Science Award, <strong>and</strong><br />

three honorary doctorates (Gent, Belgium, in<br />

1995, Potchefstroom University in South Africa<br />

in 2003, <strong>and</strong> London University, UK in 2004).<br />

<strong>2012</strong> AAPS Annual Meeting <strong>and</strong> <strong>Exposition</strong> 13


award rEcIpIEnTs<br />

The IpEc foundation Industry<br />

research achievement in Excipient<br />

Technology award<br />

The Industry Research Achievement in<br />

Excipient Technology Award is to recognize<br />

individuals working in an industrial setting<br />

who have made significant contributions in<br />

the filed <strong>of</strong> excipient technology.<br />

Brian a c carlin, ph.d.<br />

fMC biOPOlyMer<br />

Pr<strong>of</strong>essor Brian Carlin is Director <strong>of</strong> Open<br />

Innovation (Pharma), at FMC BioPolymer.<br />

He was previously the Global Mgr<br />

Pharmaceutical R&D <strong>and</strong> has been with FMC<br />

for seventeen years. Pr<strong>of</strong>essor Carlin chairs<br />

the IPEC Americas Quality by Design <strong>and</strong><br />

Excipient Composition Committees <strong>and</strong> also<br />

serves on the USP Excipient Committee.<br />

Prior to joining FMC Pr<strong>of</strong>essor Carlin<br />

worked at SmithKline & French/SmithKline<br />

Beecham in new product development<br />

for eleven years. He started in the industry<br />

with Richardson Vicks, working for five<br />

years in commercial product development.<br />

He obtained his doctorate in Interfacial<br />

Rheology from the School <strong>of</strong> Pharmacy,<br />

University <strong>of</strong> London, <strong>and</strong> an Honours<br />

degree in Pharmacy from the University<br />

<strong>of</strong> Aston in Birmingham. He serves on the<br />

distance learning MSc course at Demontfort<br />

University, UK, where he is an honorary<br />

visiting Pr<strong>of</strong>essor. Pr<strong>of</strong>essor Carlin has been<br />

a leading advocate for innovative scientific<br />

approaches to excipients <strong>and</strong> pharmaceutics<br />

in pursuit <strong>of</strong> the QbD vision <strong>of</strong> the 21st<br />

century cGMP initiative.<br />

14<br />

Awards Program<br />

Outst<strong>and</strong>ing manuscript award in<br />

analysis <strong>and</strong> pharmaceutical Quality<br />

SPOnSOred by Celgene<br />

The AAPS Outst<strong>and</strong>ing Manuscript Award<br />

in Analysis <strong>and</strong> Pharmaceutical Quality<br />

is intended to recognize outst<strong>and</strong>ing<br />

achievement in Pharmaceutical Analysis<br />

<strong>and</strong> Quality as demonstrated by author(s)<br />

in a manuscript published in an analytically<br />

focused journal.<br />

raj suryanarayanan, ph.d.<br />

univerSity Of MinneSOtA<br />

Kapildev K. arora, ph.d.<br />

univerSity Of MinneSOtA<br />

nitin g. Tayade, ph.d.<br />

univerSity Of MinneSOtA


Outst<strong>and</strong>ing manuscript award in<br />

modeling <strong>and</strong> simulation<br />

SPOnSOred by Projections research<br />

The AAPS Outst<strong>and</strong>ing Manuscript in<br />

Modeling <strong>and</strong> Simulation Award is intended<br />

to recognize outst<strong>and</strong>ing achievement<br />

in modeling <strong>and</strong> simulation in clinical<br />

pharmacology <strong>and</strong> translational research as<br />

demonstrated by the author in the quality<br />

<strong>and</strong> originality <strong>of</strong> a manuscript published in<br />

any peer-reviewed journal.<br />

paulo paixão, ph.d.<br />

univerSity Of liSbOn, POrtugAl<br />

José a.g. morais, ph.d.<br />

univerSity Of liSbOn, POrtugAl<br />

luís f. gouveia, ph.d.<br />

univerSity Of liSbOn, POrtugAl<br />

award rEcIpIEnTs<br />

Pharmaceutical Research meritorious<br />

manuscript award<br />

SPOnSOred by Pfizer inc.<br />

The AAPS Pharmaceutical Research<br />

Meritorious Manuscript Award recognizes<br />

outst<strong>and</strong>ing achievement in the<br />

pharmaceutical sciences as demonstrated<br />

by the author in the quality <strong>and</strong> originality <strong>of</strong><br />

a manuscript published in the <strong>of</strong>ficial AAPS<br />

journal, Pharmaceutical Research.<br />

Underst<strong>and</strong>ing the Behavior <strong>of</strong> Amorphous<br />

Pharmaceutical Systems during Dissolution<br />

Pharmaceutical Research, 27, Number 4<br />

(2010), DOI: 10.1007/s11095-009-0021-1<br />

lynne s. Taylor, ph.d. david E. alonzo, ph.d.<br />

Purdue univerSity AbbOtt lAbOrAtOrieS<br />

deliang Zhou, ph.d. Yi gao, ph.d.<br />

AbbOtt lAbOrAtOrieS AbbOtt lAbOrAtOrieS<br />

ge<strong>of</strong>f g.Z. Zhang, ph.d.<br />

AbbOtt lAbOrAtOrieS<br />

<strong>2012</strong> AAPS Annual Meeting <strong>and</strong> <strong>Exposition</strong> 15


<strong>aaps</strong> fEllOws<br />

<strong>aaps</strong> fellows<br />

AAPS confers the honor <strong>of</strong> Fellow to recognize individuals for outst<strong>and</strong>ing contributions,<br />

which elevate the stature <strong>of</strong> the pharmaceutical sciences, <strong>and</strong> for pr<strong>of</strong>essional excellence<br />

in the field relevant to the mission <strong>of</strong> AAPS. The primary criterion for selection as an AAPS<br />

Fellow is pr<strong>of</strong>essional competence reflected through scholarly <strong>and</strong> research contributions<br />

to the pharmaceutical sciences such as original articles, scientific presentations at <strong>annual</strong><br />

<strong>meeting</strong>s, <strong>and</strong>/or patents.<br />

Okezie I. aruoma, m.B.a., d. sc., ph.d.<br />

AMeriCAn univerSity Of heAlth SCienCeS<br />

Dr. Aruoma has developed an internationally<br />

recognized program in translational<br />

sciences research with direction focused<br />

on the underst<strong>and</strong>ing the bioefficacy <strong>of</strong><br />

functional nutraceuticals derived from fruits,<br />

vegetables <strong>and</strong> medicinal plants <strong>and</strong> how<br />

these may potentially prevent or reverse<br />

the promotion or progression <strong>of</strong> the chronic<br />

diseases with overt inflammation (such<br />

as diabetes, cancers, rheumatoid arthritis,<br />

Parkinson’s <strong>and</strong> Alzheimer’s). The associated<br />

cognitive functions impairment, movement,<br />

psychopathological <strong>and</strong> behavioral disorders<br />

significantly decreases the quality <strong>of</strong> life. Dr<br />

Aruoma’s research team assessed the effect<br />

<strong>of</strong> black tea on risk factors <strong>of</strong> cardiovascular<br />

disease in patients with diabetes <strong>and</strong><br />

in normal population at risk <strong>of</strong> diabetes<br />

<strong>and</strong> found that black tea consumption<br />

reduces uric acid <strong>and</strong> C-reactive protein<br />

levels <strong>and</strong> decreased the LDL/HDL ratio,<br />

an outcome that may benefit humans<br />

at high risk <strong>of</strong> cardiovascular events <strong>and</strong><br />

may augment prescription drug therapy.<br />

The long term objectives <strong>of</strong> Dr Aruoma’s<br />

research is enshrined in the context <strong>of</strong><br />

the search for functional nutraceuticals<br />

as neuroprotectants, cardioprotectants<br />

<strong>and</strong> cognitive enhancers with proven<br />

bioefficacy that not only meet the public<br />

health concerns but can be responsive to a<br />

comprehensive portfolio <strong>of</strong> biomarkers that<br />

can benefit testing for the complications <strong>of</strong><br />

diabetes <strong>and</strong> neurodegenerative diseases.<br />

16<br />

Awards Program<br />

alekha K. dash, r.ph., ph.d.<br />

CreightOn univerSity<br />

Dr. Alekha K. Dash received his bachelor’s<br />

<strong>and</strong> master’s degrees in Pharmacy from<br />

Jadavpur University, India, <strong>and</strong> a Ph.D.<br />

from the University <strong>of</strong> Minnesota. He is<br />

pr<strong>of</strong>essor <strong>and</strong> chair <strong>of</strong> the Department <strong>of</strong><br />

Pharmacy Sciences, Creighton University,<br />

<strong>and</strong> holds the Gilbert F. Taffe Jr. Endowed<br />

Chair <strong>of</strong> Pharmacy. Dr. Dash’s research<br />

interests include design <strong>and</strong> evaluation <strong>of</strong><br />

novel drug delivery systems, preformulation<br />

studies, solid-state pharmaceutics, <strong>and</strong><br />

pharmaceutical analysis. Dr. Dash has made<br />

unique <strong>and</strong> outst<strong>and</strong>ing contributions to<br />

numerous facets <strong>of</strong> pharmaceutical analysis.<br />

In light <strong>of</strong> his interest in drug delivery,<br />

the analytical methods developed were<br />

applied to the fabrication <strong>and</strong> evaluation <strong>of</strong><br />

novel drug delivery systems. In situ gel for<br />

sustained drug delivery <strong>and</strong> targeting, solidlipid<br />

nanoparticles for tumor localization, <strong>and</strong><br />

nanoparticulate delivery for HIV treatment<br />

are few examples. He has received several<br />

awards for teaching, research, <strong>and</strong> service.<br />

Dr. Dash has more than 50 peer reviewed<br />

publications, 120 poster <strong>and</strong> podium<br />

presentations, <strong>and</strong> several approved patents.<br />

He is a member <strong>of</strong> six pr<strong>of</strong>essional societies,<br />

serves on numerous editorial boards, <strong>and</strong><br />

is a reviewer for 20 peer-reviewed journals.<br />

He has authored chapters in a number <strong>of</strong><br />

texts, <strong>and</strong> has been an invited speaker at the<br />

international, national, <strong>and</strong> local levels.


melgardt m. de Villiers, B. pharm., ph.d.<br />

univerSity Of wiSCOnSin – MAdiSOn<br />

Dr. de Villiers <strong>of</strong> the University <strong>of</strong> Wisconsin,<br />

has developed an internationally recognized<br />

research program in the application<br />

<strong>of</strong> thin coatings to improve the solidstate<br />

properties <strong>of</strong> drugs <strong>and</strong> excipients.<br />

This program has revolved around the<br />

application <strong>of</strong> layer-by-layer self-assembled<br />

nanocoatings on pharmaceutically<br />

important surfaces. His group was the first<br />

to apply this technology to create slow<br />

release nanoparticles (furosemide <strong>and</strong><br />

dexamethasone), protective nanoshells<br />

(photo-protection <strong>of</strong> light sensitive drugs)<br />

around drug particles <strong>and</strong> to produce<br />

improved excipients (directly compressible<br />

lignocellulose). Dr. de Villiers is also an<br />

adjunct-pr<strong>of</strong>essor in the School <strong>of</strong> Pharmacy<br />

at North-West University, South Africa.<br />

With his colleagues from South Africa their<br />

work on the quality <strong>of</strong> drug <strong>and</strong> excipient<br />

raw materials has made several important<br />

contributions. For example, this work has<br />

led to several publications highlighting the<br />

importance <strong>of</strong> recognizing that polymorph<br />

identification plays a role in the quality <strong>of</strong><br />

generic drugs. His work on the effect <strong>of</strong><br />

mebendazole has led to a change in The<br />

International Pharmacopoeia (4th Edition<br />

<strong>of</strong> the International Pharmacopoeia, WHO).<br />

This monograph now clearly states “…<br />

Mebendazole exhibits polymorphism. The<br />

polymorph specified in the monograph<br />

(form C) corresponds to the crystal form <strong>of</strong><br />

mebendazole RS.”<br />

<strong>aaps</strong> fEllOws<br />

glen s. Kwon, ph.d.<br />

univerSity Of wiSCOnSin – MAdiSOn<br />

Dr. Kwon is a pr<strong>of</strong>essor <strong>and</strong> holder <strong>of</strong> the<br />

inaugural Jens T. Carstensen Distinguished<br />

Chair in the School <strong>of</strong> Pharmacy at the<br />

University <strong>of</strong> Wisconsin. His research<br />

program focuses on polymeric assemblies<br />

for drug delivery, non-viral gene delivery<br />

<strong>and</strong> optical imaging. In this context, his<br />

interests in pharmaceutical research include<br />

drug solubilization, controlled release<br />

<strong>and</strong> tumor targeting. His research team<br />

has extensively studied amphiphilic block<br />

copolymer (ABC) micelles as nanoscopic<br />

supramolecular core/shell structures for<br />

drug delivery. The design <strong>and</strong> chemistry<br />

<strong>of</strong> ABC micelles has addressed drug<br />

loading for drug solubilization, safety for<br />

intravenous injection, pharmacokinetics <strong>and</strong><br />

extracellular or intracellular drug release. He<br />

has pioneered multiple drug solubilization<br />

by ABC micelles using physical interactions<br />

<strong>and</strong> chemical pro-drug strategies. In the<br />

former case, simple changes in side chains<br />

<strong>of</strong> a core-forming block have been used to<br />

tune drug loading <strong>and</strong> release. In the latter<br />

case, drug release depends on pH, providing<br />

a strategy for triggered multi-drug release<br />

in endosomes/lysosomes <strong>of</strong> cancer cells. Dr.<br />

Kwon participates in collaborative research<br />

on multi-modal therapeutic strategies that<br />

involve hybrid nanomedicines that are<br />

bio-responsive, synergistic <strong>and</strong> theranostic,<br />

aiming for progress against lung, breast <strong>and</strong><br />

ovarian cancers <strong>and</strong> life-threatening systemic<br />

fungal diseases.<br />

<strong>2012</strong> AAPS Annual Meeting <strong>and</strong> <strong>Exposition</strong> 17


<strong>aaps</strong> fEllOws<br />

Tarun K. m<strong>and</strong>al, m. pharm., ph.d.<br />

xAvier univerSity Of lOuiSiAnA<br />

Dr. M<strong>and</strong>al is an Endowed Pr<strong>of</strong>essor <strong>of</strong><br />

Pharmacy at Xavier University <strong>of</strong> Louisiana.<br />

He has been recognized for his outst<strong>and</strong>ing<br />

contributions in the area <strong>of</strong> novel <strong>and</strong><br />

innovative drug delivery. His research<br />

focuses on the design <strong>and</strong> development <strong>of</strong><br />

commercially viable formulations to improve<br />

the safety, efficacy, <strong>and</strong> patient compliance.<br />

Cutting-edge research in his laboratory has<br />

resulted in controlled release formulations<br />

<strong>of</strong> many therapeutic agents. The<br />

microencapsulation techniques developed<br />

in his lab have resulted in effective control<br />

release formulations for large <strong>and</strong> small<br />

molecules with varying water solubility. His<br />

group has developed a film coating process<br />

that permits a less complex application <strong>of</strong><br />

multiple coats on a substrate to control the<br />

release <strong>of</strong> active ingredients. Working in<br />

the area <strong>of</strong> Nanotechnology, his group has<br />

developed orally active nanoparticles to<br />

treat radiation injury. The use <strong>of</strong> siRNA for<br />

the treatment <strong>of</strong> life threatening diseases<br />

like cancer <strong>and</strong> infectious diseases is another<br />

area <strong>of</strong> interest <strong>of</strong> his group. His group has<br />

developed a novel lipid based non-toxic<br />

siRNA-nanoparticle for the treatment <strong>of</strong><br />

Hepatitis C. He has published close to 200<br />

original research paper, review, abstracts,<br />

<strong>and</strong> monographs <strong>and</strong> filed four patents.<br />

18<br />

Awards Program<br />

mehul u. mehta, ph.d.<br />

u.S. fOOd And drug AdMiniStrAtiOn<br />

Dr. Mehta has been the Director <strong>of</strong> Division<br />

<strong>of</strong> Clinical Pharmacology (CP) I in CDER,<br />

FDA for the last 14 years. During this<br />

period, he has worked tirelessly to bring<br />

out regulatory guidances in the areas <strong>of</strong><br />

Biopharmaceutics <strong>and</strong> CP with the intent to<br />

avoid unnecessary human bioequivalence<br />

studies, based on robust science, <strong>and</strong> to<br />

guide drug development by defining best<br />

practices in CP. Thus, under his leadership,<br />

the Agency issued two guidances with<br />

significant <strong>and</strong> positive impact. The first<br />

one, “SUPAC – MR” guidance provided<br />

regulatory relief to the manufacturers <strong>of</strong><br />

modified release products when faced<br />

with scale-up <strong>and</strong> post-approval changes,<br />

based on judicious in-vitro <strong>and</strong> in-vivo<br />

tests. The second guidance, “PK in Hepatic<br />

Impairment”, st<strong>and</strong>ardized the conduct <strong>and</strong><br />

assessment <strong>of</strong> pharmacokinetic studies in<br />

hepatic impairment for all new drugs <strong>and</strong><br />

has played a pivotal part in proper dosing<br />

recommendations in this important patient<br />

population for hundreds <strong>of</strong> new drugs. Dr.<br />

Mehta is also a leading Agency scientist on<br />

the Biopharmaceutics Classification System<br />

(BCS) <strong>and</strong> has been the co-chair <strong>of</strong> the<br />

CDER BCS Committee for last 8 years where<br />

he has helped the Agency implement the<br />

BCS guidance <strong>and</strong> granting <strong>of</strong> BCS based<br />

biowaivers for nearly 100 drug products.


michael a. repka, d.d.s., ph.d.<br />

univerSity Of MiSSiSSiPPi<br />

Dr. Michael A. Repka’s most important<br />

scientific accomplishments involve the<br />

advancement <strong>of</strong> hot melt extrusion (HME)<br />

technology. He has established himself<br />

as an expert in this major pharmaceutical<br />

processing field, through his numerous<br />

peer-reviewed publications, presentations<br />

<strong>and</strong> scientific talks. Polymeric drug delivery<br />

design <strong>and</strong> stabilization, formulation <strong>and</strong><br />

process development for natural products,<br />

antifungal/antibacterial agents <strong>and</strong><br />

vaccines, are important components <strong>of</strong> his<br />

research. He has contributed significantly<br />

to several drug delivery areas including<br />

oral, transdermal/trans-nail, nose-to-brain,<br />

<strong>and</strong> transcorneal delivery. Dr. Repka is<br />

Chair <strong>and</strong> Pr<strong>of</strong>essor <strong>of</strong> the Department<br />

<strong>of</strong> Pharmaceutics <strong>and</strong> Director <strong>of</strong> the Pii<br />

Center for Pharmaceutical Technology at<br />

The University <strong>of</strong> Mississippi. He joined<br />

The University <strong>of</strong> Mississippi faculty after<br />

receiving his Ph.D. from The University<br />

<strong>of</strong> Texas, College <strong>of</strong> Pharmacy, <strong>and</strong> also<br />

founded a pharmaceutical research/<br />

development company specializing in drug<br />

delivery. Dr. Repka serves on the Editorial<br />

Advisory Boards <strong>of</strong> six prestigious journals,<br />

is Associate Editor for AAPS PharmSciTech<br />

<strong>and</strong> Editor for North America for Journal<br />

<strong>of</strong> Drug Delivery Science <strong>and</strong> Technology.<br />

He served as Chair <strong>of</strong> the Modified Release<br />

Focus Group (2011) <strong>and</strong> was subsequently<br />

elected Vice Chair <strong>of</strong> the Formulation Design<br />

<strong>and</strong> Development Section within AAPS.<br />

Dr. Repka regularly speaks at international<br />

HME symposia <strong>and</strong> workshops.<br />

<strong>aaps</strong> fEllOws<br />

lynne s. Taylor, ph.d.<br />

Purdue univerSity<br />

Dr. Taylor is well known for her research<br />

program in the area <strong>of</strong> the solid-state phase<br />

behavior <strong>of</strong> pharmaceutical materials. In<br />

particular, she has addressed the phase<br />

behavior <strong>of</strong> high energy solids such as<br />

amorphous forms, which are <strong>of</strong> interest<br />

for the delivery <strong>of</strong> poorly water soluble<br />

compounds. Much <strong>of</strong> her research in the<br />

area has revolved around the exploration <strong>of</strong><br />

polymers to inhibit crystallization <strong>of</strong> the drug<br />

from the formulation <strong>and</strong> the supersaturated<br />

solution generated upon dissolution <strong>of</strong><br />

the enabling formulation. Other important<br />

areas <strong>of</strong> research include addressing the<br />

role <strong>of</strong> water-solid interactions in promoting<br />

chemical <strong>and</strong> physical instabilities, as well<br />

as the investigation <strong>and</strong> application <strong>of</strong><br />

advanced analytical techniques for solidstate<br />

characterization. The long term<br />

goal <strong>of</strong> Dr. Taylor’s research is to gain<br />

a comprehensive underst<strong>and</strong>ing <strong>of</strong> the<br />

interplay between solid-state properties<br />

<strong>and</strong> drug performance in vivo.<br />

<strong>2012</strong> AAPS Annual Meeting <strong>and</strong> <strong>Exposition</strong> 19


<strong>aaps</strong> fEllOws<br />

Timothy s. Tracy, ph.d.<br />

univerSity Of KentuCKy<br />

Dr. Tracy has developed an internationally<br />

recognized program in the area <strong>of</strong><br />

human drug metabolism <strong>and</strong> disposition,<br />

centering on the role <strong>of</strong> cytochrome P450<br />

drug metabolizing enzymes, specifically<br />

CYP2C9. This has involved examination<br />

<strong>of</strong> the structure-function relationship <strong>of</strong><br />

CYP2C9 resulting in some <strong>of</strong> the seminal<br />

work on the conformational plasticity <strong>of</strong><br />

the P450 enzymes leading to a better<br />

underst<strong>and</strong>ing <strong>of</strong> not only their broad<br />

substrate specificity but also atypical<br />

enzyme kinetics. The work has exp<strong>and</strong>ed<br />

to examine the role in pharmacogenetics <strong>of</strong><br />

CYP2C9 in altering substrate metabolism<br />

<strong>and</strong> how pharmacogenetics can impact<br />

drug-drug interactions. Work from his<br />

laboratory has demonstrated that reduced<br />

activity allelic variants <strong>of</strong> CYP2C9 can<br />

significantly attenuate drug-drug interaction<br />

potential in humans <strong>and</strong> necessitate<br />

differential alterations in drug dose based<br />

on an individual’s genotype in cases where<br />

interacting drugs must be co-administered.<br />

More recently, this research has examined<br />

the role <strong>of</strong> protein-protein interactions<br />

among the cytochrome P450 enzymes<br />

<strong>and</strong> how these interactions may alter<br />

drug metabolism capacity. The long term<br />

objective <strong>of</strong> Dr. Tracy’s research is to develop<br />

predictive models <strong>of</strong> in vivo human drug<br />

metabolism <strong>and</strong> drug-drug interactions from<br />

in vitro data to improve therapeutic efficacy<br />

<strong>and</strong> minimize toxicity.<br />

20<br />

Awards Program<br />

Jeffry g. weers, ph.d.<br />

nOvArtiS PhArMACeutiCAl COrPOrAtiOn<br />

Evans <strong>and</strong> Wennerström noted that the<br />

colloidal domain is where biology, chemistry,<br />

physics, <strong>and</strong> technology meet. Nowhere is<br />

this more important than in the field <strong>of</strong> drug<br />

delivery. Dr. Weers’ career has focused on<br />

the development <strong>of</strong> engineered particles<br />

for biomedical <strong>and</strong> consumer products.<br />

He is an inventor <strong>of</strong> 40 patents with an<br />

additional 45 published patents pending.<br />

Among his inventions are a blood substitute<br />

formulation based on nanoemulsion droplets<br />

<strong>of</strong> perfluorooctyl bromide (Oxygent),<br />

<strong>and</strong> an ultrasound contrast agent based<br />

on microbubbles <strong>of</strong> perfluorohexane<br />

(Imagent®). More recently, his research has<br />

focused on finding better ways to deliver<br />

drugs via inhalation. In this regard, Dr. Weers<br />

designed aerosol formulations comprising<br />

hollow porous particles (PulmoSphere<br />

technology) for use in portable inhalers.<br />

The PulmoSphere technology was utilized<br />

in the development <strong>of</strong> the TOBI ® Podhaler,<br />

a dry powder formulation <strong>of</strong> tobramycin<br />

for the treatment <strong>of</strong> chronic Pseudomonas<br />

aeruginosa infections in cystic<br />

fibrosis patients.


spEcIal<br />

rEcOgnITIOns<br />

philip r. mayer, ph.d.<br />

AAPS PASt PreSident<br />

wayne r. gombotz, ph.d.<br />

AAPS treASurer<br />

marilyn E. morris, ph.d.<br />

AAPS MeMber-At-lArge<br />

spEcIal rEcOgnITIOns<br />

rEpOrT Of<br />

THE prEsIdEnT<br />

david Y. mitchell, ph.d.<br />

AAPS PreSident<br />

<strong>2012</strong> AAPS Annual Meeting <strong>and</strong> <strong>Exposition</strong> 21


award rEcIpIEnTs<br />

<strong>aaps</strong> research achievement awards<br />

The AAPS Research Achievement Awards are intended to recognize outst<strong>and</strong>ing scientists<br />

who have conducted fundamental research that has had significant impact in the fields <strong>of</strong><br />

Drug Discovery <strong>and</strong> Development Interface (DDDI), Formulation Design <strong>and</strong> Development<br />

(FDD), <strong>and</strong> Pharmacokinetics, Pharmacodynamics <strong>and</strong> Drug Metabolism (PPDM).<br />

<strong>aaps</strong> research achievement<br />

award in drug discovery <strong>and</strong><br />

development Interface<br />

SPOnSOred by Allergan<br />

aleem gangjee, ph.d.<br />

duQueSne univerSity<br />

Some <strong>of</strong> the most important strides against<br />

cancer in the past few years have come from<br />

combination chemotherapy. However, the<br />

use <strong>of</strong> two or more separate agents have<br />

disadvantages such as pharmacokinetic<br />

differences <strong>of</strong> the drugs that may preclude<br />

the concept <strong>of</strong> combination chemotherapy,<br />

cost <strong>of</strong> two or more drugs <strong>and</strong> patient<br />

compliance among others. In an attempt<br />

to circumvent such drawbacks, Dr. Gangjee<br />

<strong>and</strong> co-workers designed, synthesized <strong>and</strong><br />

evaluated single agents with “combination<br />

chemotherapy” attributes. These single<br />

agents target cancer cells at two or more<br />

different sites. The dual <strong>and</strong> multitargeting<br />

single agents that Dr. Gangjee <strong>and</strong><br />

co-workers have developed include<br />

dihydr<strong>of</strong>olate reductase <strong>and</strong> thymidylate<br />

synthase targeting agents; antiangiogenic<br />

<strong>and</strong> thymidylate synthase targeting agents;<br />

antimitotic <strong>and</strong> antiangiogenic agents;<br />

P13K, mTOR <strong>and</strong> purine synthesis inhibitors;<br />

tumor selective folate transport <strong>and</strong> purine<br />

synthesis inhibitors. A number <strong>of</strong> these<br />

rationally designed drugs are in preclinical<br />

development <strong>and</strong> show remarkable efficacy<br />

in in vivo animal tumor xenograft models<br />

<strong>and</strong> are poised for possible clinical trials.<br />

22<br />

Awards Program<br />

Dr. Gangjee will be speaking on Tuesday,<br />

October 16, from 8:30 am – 11:00 am<br />

in Room W185 at the McCormick Place<br />

Convention Center.<br />

<strong>aaps</strong> research achievement award in<br />

formulation design <strong>and</strong> development<br />

SPOnSOred by Pfizer inc.<br />

mansoor a. Khan, r.ph., ph.d.<br />

u.S. fOOd And drug AdMiniStrAtiOn<br />

Dr. Khan is a Senior Biomedical Research<br />

Scientist (SBRS) <strong>and</strong> serves as the Director<br />

<strong>of</strong> Product Quality Research in the Center<br />

for Drug Evaluation <strong>and</strong> Research (CDER)<br />

in FDA. Prior to joining FDA in 2004, Dr.<br />

Khan was a Pr<strong>of</strong>essor <strong>of</strong> Pharmaceutics<br />

<strong>and</strong> Director <strong>of</strong> Graduate Program in the<br />

School <strong>of</strong> Pharmacy at Texas Tech University.<br />

He earned his Ph.D. in Industrial Pharmacy<br />

from the St. John’s University School <strong>of</strong><br />

Pharmacy in 1992. He has published over<br />

210 peer-reviewed manuscripts, four texts,<br />

15 book chapters, <strong>and</strong> has been invited to<br />

give more than 150 presentations worldwide.<br />

Dr. Khan’s research focuses primarily<br />

in the area <strong>of</strong> drug formulations design <strong>and</strong><br />

development <strong>of</strong> “challenging molecules.”<br />

It encompasses pediatric dosage forms,<br />

nanoparticles, modified release dosage<br />

forms, biosimilar characterization, particulate<br />

engineering, <strong>and</strong> scientific underpinnings<br />

<strong>of</strong> Quality by Design utilizing novel Process<br />

Analytical Technologies. As the Director


<strong>of</strong> Product Quality Research, Dr. Khan<br />

serves as CDER’s principal advisor on all<br />

matters related to planning <strong>and</strong> conducting<br />

research to study the impact on product<br />

quality, changes in bulk drug substances,<br />

formulation component <strong>and</strong> composition,<br />

<strong>and</strong> manu-facturing equipment <strong>and</strong><br />

processes.<br />

As a recognized expert, Dr. Khan participates<br />

fully in policy formulation; planning <strong>and</strong><br />

evaluating programs, including oversight<br />

<strong>of</strong> pharmaceutical science activities to<br />

insure that basic <strong>and</strong> original research are<br />

considered in major CDER decisions. He<br />

maintains contact with “state <strong>of</strong> the science”<br />

in order to integrate the most advanced<br />

research theory or practice in the field <strong>of</strong><br />

pharmaceutical science into the Center’s<br />

new, generic, <strong>and</strong> biotech drug programs.<br />

Dr. Khan is an AAPS Fellow, <strong>and</strong> serves<br />

on the editorial board <strong>of</strong> several leading<br />

journals.<br />

Dr. Khan will be speaking on Tuesday,<br />

October 16, from 8:30 am – 12:00 pm<br />

in Room W196 at the McCormick Place<br />

Convention Center.<br />

<strong>aaps</strong> research achievement award in<br />

pharmacokinetics, pharmacodynamics,<br />

<strong>and</strong> drug metabolism<br />

SPOnSOred by Aptalis Pharmaceutical<br />

technologies<br />

Jashvant d. unadkat, ph.d.<br />

univerSity Of wAShingtOn<br />

Dr. Jashvant (Jash) Unadkat’s laboratory has<br />

established an international reputation in<br />

the area <strong>of</strong> mechanisms <strong>of</strong> drug transport,<br />

metabolism <strong>and</strong> drug interactions (DDI)<br />

<strong>and</strong> in the impact <strong>of</strong> physiological <strong>and</strong><br />

pathological changes on these processes.<br />

Translating findings from the bench to<br />

the bedside is a hallmark <strong>of</strong> his laboratory.<br />

award rEcIpIEnTs<br />

His laboratory was the first to measure<br />

P-glycoprotein activity <strong>and</strong> its inhibition at<br />

the human blood-brain barrier (BBB) using<br />

a novel PET imaging technique. Based on<br />

these studies, it is now widely accepted that<br />

inadvertent P-gp DDI at the human BBB are<br />

unlikely to occur except when the drug is<br />

predominately excluded from the brain by<br />

P-gp. In addition, his laboratory has found<br />

that the activity <strong>of</strong> P-gp at the BBB, which<br />

transports beta-amyloid out <strong>of</strong> the brain, is<br />

compromised in Alzheimer’s disease. This<br />

finding could result in novel ways to treat<br />

this disease. Further, Dr. Unadkat’s work has<br />

the potential to increase the effectiveness<br />

<strong>of</strong> drugs in the treatment <strong>of</strong> diseases such<br />

as hepatitis C. Specifically, he has found<br />

that the dosing regimens <strong>of</strong> ribavirin as it<br />

is typically used to treat hepatitis C may<br />

not be optimal because the distribution <strong>of</strong><br />

ribavirin into hepatocytes (the target site)<br />

is saturated.<br />

Dr. Unadkat will be speaking on Tuesday,<br />

October 16, from 8:30 am – 12:00 pm<br />

in Room W184 at the McCormick Place<br />

Convention Center.<br />

<strong>2012</strong> AAPS Annual Meeting <strong>and</strong> <strong>Exposition</strong> 23


award recipients<br />

<strong>aaps</strong> regulatory sciences<br />

achievement award<br />

SPOnSOred by novartis vaccines <strong>and</strong><br />

diagnostics, inc.<br />

Vijay Kumar Tammara, ph.d.<br />

nurOn biOteCh inC.<br />

Dr. Tammara previously served as a Director,<br />

Regulatory Affairs at Merck & Co., Inc., Senior<br />

Associate Director at Wyeth Pharmaceuticals<br />

<strong>and</strong> as an Assistant Director at San<strong>of</strong>i-<br />

Synthelabo in Worldwide Regulatory Affairs.<br />

Prior to his industrial positions, Dr. Tammara<br />

held increasingly responsible positions<br />

in the Office <strong>of</strong> Clinical Pharmacology<br />

<strong>and</strong> Biopharmaceutics at the FDA <strong>and</strong><br />

received several FDA awards including the<br />

CDER Outst<strong>and</strong>ing Reviewer Award, FDA<br />

Outst<strong>and</strong>ing Achievement Award, Group<br />

Recognition Awards, Center Director’s<br />

Special Citation Awards, CDER Team<br />

Excellence Awards, Team Spirit Awards, <strong>and</strong><br />

Awards <strong>of</strong> Excellence. His industrial awards<br />

include Merck’s Awards <strong>of</strong> Excellence in<br />

2004, 2005, 2007, 2009, <strong>and</strong> 2010 <strong>and</strong><br />

Special Recognition Awards in 2007, 2008,<br />

2009, <strong>and</strong> 2010. He is also the recipient <strong>of</strong><br />

the AAPS RS Section Recognition Awards<br />

in 2004, 2007 <strong>and</strong> 2008. He also received<br />

the 2009 Distinguished Scientist Award<br />

from the <strong>American</strong> <strong>Association</strong> <strong>of</strong> Indian<br />

Pharmaceutical Scientists.<br />

24<br />

Awards Program<br />

dale E. wurster research award<br />

in pharmaceutics<br />

SPOnSOred by dale eric <strong>and</strong> Pamela A.<br />

wurster/Susan wurster biel<br />

The purpose <strong>of</strong> this award is to recognize<br />

individuals who have made significant<br />

research contributions to the pharmaceutical<br />

sciences in the specific field <strong>of</strong><br />

pharmaceutics.<br />

Bradley d. <strong>and</strong>erson, ph.d.<br />

univerSity Of KentuCKy<br />

Dr. Anderson focuses on mechanismbased<br />

predictive relationships linking<br />

drug molecular structure, speciation,<br />

<strong>and</strong> intermolecular interactions to<br />

pharmaceutically relevant physical<br />

properties such as solubility <strong>and</strong><br />

solubilization in formulations, chemical<br />

& physical stability <strong>of</strong> solutions <strong>and</strong><br />

amorphous solids, <strong>and</strong> membrane<br />

transport/drug delivery. His research<br />

combines experimental studies, molecular<br />

dynamics computer simulations, <strong>and</strong><br />

mathematical model development<br />

founded on physical <strong>and</strong> physical organic<br />

chemistry to underst<strong>and</strong> <strong>and</strong> optimize<br />

drug developability, formulation quality,<br />

<strong>and</strong> delivery system performance. Several<br />

prodrugs or delivery systems designed or<br />

explored in Dr. Anderson’s laboratories have<br />

been patented <strong>and</strong> some have advanced<br />

to clinical studies or commercialization.<br />

Biophysical insights <strong>and</strong> quantitative<br />

relationships between passive membrane<br />

transport <strong>and</strong> structure stemming from his<br />

investigations <strong>of</strong> drug permeability across<br />

lipid bilayer membranes have advanced<br />

underst<strong>and</strong>ing <strong>of</strong> drug transport across<br />

biomembrane barriers including the skin,<br />

oral mucosa, <strong>and</strong> blood-brain barrier <strong>and</strong> led<br />

to the design <strong>of</strong> lipid-based drug delivery<br />

systems with tunable drug release kinetics<br />

for cancer chemotherapy. Recently, he has


contributed to a mechanistic underst<strong>and</strong>ing<br />

<strong>of</strong> the chemical <strong>and</strong> physical stability <strong>of</strong><br />

amorphous solid formulations by taking<br />

into account mobility effects on competing<br />

pathways governing the fate <strong>of</strong> reactive<br />

intermediates during chemical degradation<br />

<strong>and</strong> utilizing molecular dynamics computer<br />

simulations to explore specific drugexcipient<br />

interactions governing physical<br />

stability <strong>and</strong> performance.<br />

distinguished service award<br />

SPOnSOred by San<strong>of</strong>i<br />

The AAPS Distinguished Service Award<br />

is intended to recognize distinguished<br />

service in advancing the pharmaceutical<br />

sciences <strong>and</strong> the <strong>American</strong> <strong>Association</strong> <strong>of</strong><br />

Pharmaceutical Scientists.<br />

larry l. augsburger, ph.d.<br />

university <strong>of</strong> Maryl<strong>and</strong><br />

Dr. Augsburger is an internationally<br />

recognized researcher in pharmaceutics, the<br />

broad pharmaceutical science community,<br />

as well as in the fields <strong>of</strong> process engineering<br />

<strong>and</strong> the formulation <strong>and</strong> control <strong>of</strong> dietary<br />

supplements. His research has contributed<br />

to the basic science underpinning oral solid<br />

dosage form fabrication <strong>and</strong> quality, <strong>and</strong> to<br />

the practice <strong>of</strong> manufacture <strong>and</strong> regulation<br />

<strong>of</strong> these products. His research thus deals<br />

with a highly important aspect <strong>of</strong> material<br />

sciences that has direct relevance to public<br />

health with respect to both drugs <strong>and</strong> dietary<br />

supplements. Supported by more than $13.5<br />

million in grants <strong>and</strong> contracts from the NIH,<br />

FDA <strong>and</strong> private industry, his work has been<br />

recognized by a number <strong>of</strong> awards, among<br />

which are the Federation Internationale<br />

Pharmaceutique (FIP) Industrial Pharmacy<br />

Medal, the AAPS Dale E. Wurster Research<br />

Award in Pharmaceutics, <strong>and</strong> the Dr. Patricia<br />

award recipients<br />

Sokolove Outst<strong>and</strong>ing Mentor Award for<br />

his work with graduate students. A charter<br />

member <strong>of</strong> AAPS, Dr. Augsburger has a<br />

long <strong>and</strong> distinguished record <strong>of</strong> service to<br />

AAPS <strong>and</strong> was the 1999 AAPS president. His<br />

research achievements combined with his<br />

dedicated service to AAPS have significantly<br />

<strong>and</strong> meaningfully advanced both the<br />

pharmaceutical sciences <strong>and</strong> the <strong>American</strong><br />

<strong>Association</strong> <strong>of</strong> Pharmaceutical Scientists.<br />

<strong>2012</strong> AAPS Annual Meeting <strong>and</strong> <strong>Exposition</strong> 25


OpEnIng sEssIOn<br />

IncOmIng prEsIdEnT’s<br />

rEmarKs<br />

anthony J. destefano, ph.d.<br />

AAPS PreSident-eleCt<br />

spEcIal rEcOgnITIOn<br />

colin m. minchom, ph.d.<br />

<strong>2012</strong> AnnuAl Meeting PrOgrAM ChAir<br />

Introduction <strong>of</strong> <strong>2012</strong> <strong>annual</strong> <strong>meeting</strong><br />

program committee<br />

Colin M. Minchom, Ph.D. (Chair)<br />

Christopher R. McCurdy, Ph.D. (Chair-elect)<br />

Elizabeth de Lange, Ph.D. (2013 Chair-elect)<br />

Anthony J. DeStefano, Ph.D. (Past Chair)<br />

Stephen T. Colgan, Ph.D. (APQ Section)<br />

William Nowatzke, Ph.D. (BIOTEC Section)<br />

Thaddeus H. Grasela, Pharm. D., Ph.D.<br />

(CPTR Section)<br />

Annette Bak, Ph.D., MBA (DDDI Section)<br />

Lavinia Marina Lewis, Ph.D. (FDD Section)<br />

Cynthia A. Oksanen, Ph.D. (MSE Section)<br />

Ping Gao, Ph.D. (PPB Section)<br />

Joseph W. Polli, Ph.D. (PPDM Section)<br />

Ganapathy Mohan, Ph.D. (RS Section)<br />

Russell S. Weiner, Ph.D. (EC Liaison)<br />

26<br />

Awards Program<br />

KEYnOTE addrEss<br />

rebecca skloot<br />

AuthOr; fOunder And PreSident Of the<br />

henriettA lACKS fOundAtiOn<br />

Bestselling author Rebecca Skloot spent<br />

over ten years doggedly uncovering the<br />

truth about the life, death, <strong>and</strong> ultimate<br />

“immortality” <strong>of</strong> a poor black tobacco<br />

farmer named Henrietta Lacks. In The<br />

Immortal Life <strong>of</strong> Henrietta Lacks, Skloot<br />

tells the narrative <strong>of</strong> a young black<br />

woman who died <strong>of</strong> cervical cancer in<br />

1951—<strong>and</strong> left behind an inexplicably<br />

immortal line <strong>of</strong> cells known as HeLa.<br />

Henrietta Lacks, whose cells—harvested<br />

without her knowledge or consent—<br />

contributed to scientific advancements as<br />

varied as the polio vaccine, treatments for<br />

cancers <strong>and</strong> viruses, in vitro fertilization,<br />

<strong>and</strong> the impact <strong>of</strong> space travel on human<br />

cells. Part detective story, part scientific<br />

odyssey, <strong>and</strong> part family saga, the book’s<br />

multi-layered approach raises fascinating<br />

questions about race, class, <strong>and</strong> bioethics<br />

in America.<br />

Though best-known for The Immortal<br />

Life <strong>of</strong> Henrietta Lacks, Rebecca Skloot<br />

has written more than 200 feature<br />

articles, personal essays, book reviews,<br />

<strong>and</strong> news stories for The New York<br />

Times Magazine; O, The Oprah Magazine;<br />

Discover; Columbia Journalism Review;<br />

Seed; New Yorker Magazine; Slate;<br />

Popular Science; Chicago Tribune; <strong>and</strong><br />

other publications.<br />

Rebecca Skloot has a B.S. in biological<br />

sciences <strong>and</strong> a MFA in creative<br />

nonfiction. She has taught creative<br />

writing <strong>and</strong> science journalism at the<br />

University <strong>of</strong> Memphis, the University <strong>of</strong><br />

Pittsburgh, <strong>and</strong> New York University. She<br />

is founder <strong>and</strong> president <strong>of</strong> the Henrietta<br />

Lacks Foundation.


InTrOducTIOn Of THE<br />

2013 <strong>aaps</strong> ExEcuTIVE cOuncIl<br />

anthony J. destefano, ph.d.<br />

PreSident<br />

marilyn E. morris, ph.d.<br />

PreSident-eleCt<br />

david Y. mitchell, ph.d.<br />

iMMediAte PASt PreSident<br />

phillip ramsey, m.B.a., r.a.c.<br />

treASurer<br />

James E. polli, ph.d. (2013)<br />

MeMber-At-lArge<br />

raman Venkataramanan, ph.d. (2013)<br />

MeMber-At-lArge<br />

dannette K. doolittle, ph.d. (2014)<br />

MeMber-At-lArge<br />

russell s. weiner, ph.d. (2014)<br />

MeMber-At-lArge<br />

Binodh s. desilva, ph.d. (2015)<br />

MeMber-At-lArge<br />

<strong>2012</strong> AAPS Annual Meeting <strong>and</strong> <strong>Exposition</strong> 27


<strong>aaps</strong> awards HIsTOrY<br />

<strong>aaps</strong> distinguished pharmaceutical<br />

scientist award<br />

1989 Leslie Z. Benet, Ph.D.<br />

1991 Dale E. Wurster, Ph.D.<br />

1993 Robert S. Langer, Sc.D.<br />

1995 George Zografi, Ph.D.<br />

1997 Ronald T. Borchardt, Ph.D.<br />

1999 Joseph R. Robinson, Ph.D.<br />

2001 Wolfgang Sadée, Ph.D.<br />

2003 Yuichi Sugiyama, Ph.D.<br />

2005 Gordon L. Amidon, Ph.D.<br />

2007 Nicholas S. Bodor, Ph.D.<br />

2009 Michael J. Pikal, Ph.D.<br />

2011 Valentino J. Stella, Ph.D.<br />

<strong>aaps</strong> dale E. wurster research award<br />

1990 George Zografi, Ph.D.<br />

1992 Gerhard Levy, Pharm.D.<br />

1994 William I. Higuchi, Ph.D.<br />

1996 Joseph R. Robinson, Ph.D.<br />

1998 Sung Wan Kim, Ph.D.<br />

2000 Leslie Z. Benet, Ph.D.<br />

2002 Nicholas A. Peppas, Sc.D., D.Eng.<br />

2004 David J. W. Grant, Ph.D.<br />

2006 Patrick P. DeLuca, Ph.D.<br />

2008 Larry Augsburger, Ph.D.<br />

2010 Theodore W. R<strong>and</strong>olph, Ph.D.<br />

<strong>2012</strong> Brad Anderson, Ph.D.<br />

<strong>aaps</strong> distinguished service award<br />

1990 Klaus G. Florey, Ph.D.<br />

1992 Karl A. DeSante, Ph.D.<br />

1994 Wolfgang Sadée, Ph.D.<br />

1996 Leslie Z. Benet, Ph.D.<br />

1998 Vincent H.L. Lee, Ph.D.<br />

2000 Vinod P. Shah, Ph.D.<br />

2002 Jerome P. Skelly, Ph.D.<br />

2004 Richard F. Bergstrom, Ph.D.<br />

2006 Mario L. Rocci, Jr., Ph.D.<br />

2008 Sathyanarayana (Satyam) M.<br />

Upadrashta, Ph.D., RAC<br />

2010 Ho-Leung Fung, Ph.D.<br />

<strong>2012</strong> Larry L. Augsburger, Ph.D.<br />

research achievement award in analysis<br />

<strong>and</strong> pharmaceutical Quality<br />

1988 John C. Craig, Ph.D.<br />

1990 James T. Stewart, Ph.D.<br />

1992 Kamal K. Midha, Ph.D.<br />

1994 William D. Mason, Ph.D.<br />

1996 H. Thomas Karnes, Ph.D.<br />

1998 Harry G. Brittain, Ph.D.<br />

2000 Peter Kissinger, Ph.D.<br />

2003 Bogdan Matuszewski, Ph.D.<br />

2004 Susan M. Lunte, Ph.D.<br />

2006 Mohammed Jemal, Ph.D.<br />

2008 Craig Lunte, Ph.D.<br />

2010 Michael G. Bartlett, Ph.D.<br />

28<br />

Awards Program<br />

<strong>aaps</strong> research achievement award<br />

in Biotechnology<br />

1991 Wolfgang Sadée, Ph.D.<br />

1993 Ronald T. Borchardt, Ph.D.<br />

1997 Mark C. Manning, Ph.D.<br />

1999 Charles R. Middaugh, Ph.D.<br />

2001 Francis C. Szoka, Ph.D.<br />

2003 Victor C. Yang, Ph.D.<br />

2005 Richard D. DiMarchi, Ph.D.<br />

2007 John F. Carpenter, Ph.D.<br />

2009 David Scott, Ph.D.<br />

<strong>aaps</strong> research achievement award in<br />

clinical pharmacology <strong>and</strong> Translational<br />

research (formerly clinical sciences)<br />

1991 Jerome J. Schentag, Pharm.D.<br />

1995 Daniel L. Azarn<strong>of</strong>f, M.D.<br />

1997 Roger Jelliffe, Ph.D.<br />

1998 Milap C. Nahata, MS, Pharm.D.<br />

2004 Hartmut Derendorf, Ph.D.<br />

2005 David J. Greenblatt, M.D.<br />

2007 Nick Holford, M.D., M.B., Ch.B.<br />

2009 Mark J. Ratain, MD<br />

2011 Jeffrey Barrett, Ph.D., FCP<br />

<strong>aaps</strong> research achievement<br />

award in Economic, marketing <strong>and</strong><br />

management sciences<br />

1990 Mickey C. Smith, Ph.D.<br />

1992 Charles D. Hepler, Ph.D.<br />

1994 Andy S. Stergachis, Ph.D.<br />

1996 J. Lyle Bootman, Ph.D.<br />

1998 Jeffrey A. Kotzan, Ph.D.<br />

2000 Dev S. Pathak, DBA<br />

<strong>aaps</strong> research achievement award in<br />

drug discovery <strong>and</strong> development Interface<br />

(formerly drug design <strong>and</strong> discovery)<br />

1988 Nicholas S. Bodor, Ph.D.<br />

1990 Philip S. Portoghese, Ph.D.<br />

1992 Daniel H. Rich, Ph.D.<br />

1994 Ronald T. Borchardt, Ph.D.<br />

1996 Ralph F. Hirschmann, Ph.D.<br />

1998 Kenner C. Rice, Ph.D.<br />

2000 Peter W. Schiller, Ph.D.<br />

2002 Alex<strong>and</strong>ros Makriyannis, Ph.D.<br />

2004 Rao S. Rapaka, Ph.D.<br />

2006 F. Ivy Carroll, Ph.D.<br />

2008 Lemont B. Kier, Ph.D.<br />

2010 Peter A. Crooks, Ph.D.<br />

<strong>2012</strong> Aleem Gangjee, Ph.D.<br />

<strong>aaps</strong> research achievement award in<br />

formulation design <strong>and</strong> development<br />

2010 Abu T. M. Serajuddin, Ph.D.<br />

<strong>2012</strong> Mansoor A. Khan, R.Ph., Ph.D.


<strong>aaps</strong> research achievement award in<br />

manufacturing science & Engineering<br />

2009 Dale Eric Wurster, Ph.D.<br />

2011 Ahmed Adel Sakr, Ph.D.<br />

<strong>aaps</strong> research achievement award in<br />

pharmaceutics <strong>and</strong> drug delivery<br />

1988 William I. Higuchi, Ph.D.<br />

1989 Arm<strong>and</strong>o J. Aguiar, Ph.D.<br />

1991 Joseph R. Robinson, Ph.D.<br />

1993 Felix Theeuwes, D.Sc.<br />

1995 Sung Wan Kim, Ph.D.<br />

1997 Valentino J. Stella, Ph.D.<br />

1999 Tsuneji Nagai, Ph.D.<br />

2001 Kinam Park, Ph.D.<br />

2003 Vincent H.L. Lee, Ph.D.<br />

2005 Vladimir P. Torchilin, Ph.D.<br />

2007 Mitsuru Hashida, Ph.D.<br />

<strong>aaps</strong> research achievement award<br />

in pharmacokinetics, pharmacodynamics<br />

<strong>and</strong> drug metabolism<br />

1988 Ho-Leung Fung, Ph.D.<br />

1990 Edward R. Garrett, Ph.D.<br />

1992 John G. Wagner, Ph.D.<br />

1994 Malcolm Rowl<strong>and</strong>, Ph.D.<br />

1996 Milo Gibaldi, Ph.D.<br />

1998 William J. Jusko, Ph.D.<br />

2000 Grant R. Wilkinson, Ph.D.<br />

2002 K. S<strong>and</strong>y Pang, Ph.D.<br />

2004 Jessie L-S. Au, Ph.D.<br />

2006 Kathleen Giacomini, Ph.D.<br />

2008 Ken-ichi Inui, Ph.D.<br />

2010 Meindert Danh<strong>of</strong>, Ph.D<br />

<strong>2012</strong> Jashvant D. Unadkat, Ph.D.<br />

<strong>aaps</strong> research achievement award in<br />

pharmaceutical Technologies<br />

1988 Patrick P. DeLuca, Ph.D.<br />

1989 Ralph F. Shangraw, Ph.D.<br />

1991 Stanley L. Hem, Ph.D.<br />

1993 Hans Leuenberger, Ph.D.<br />

1995 Eugene L. Parrott, Ph.D.<br />

1997 J. Keith Guillory, Ph.D.<br />

1999 Nicholas A. Peppas, Sc.D., D.Eng.<br />

2001 Michael J. Pikal, Ph.D.<br />

2003 Larry L. Augsburger, Ph.D.<br />

2005 James W. McGinity, Ph.D.<br />

2007 Steven L. Nail, Ph.D.<br />

<strong>aaps</strong> regulatory sciences<br />

achievement award<br />

2004 Jerome P. Skelly, Ph.D.<br />

2006 Ajaz S. Hussain, Ph.D.<br />

2008 Moheb M. Nasr, Ph.D.<br />

2010 Sathyanarayana (Satyam) Upadrashta,<br />

Ph.D., RAC<br />

<strong>2012</strong> Vijay Tammara, Ph.D.<br />

<strong>aaps</strong> awards HIsTOrY<br />

<strong>aaps</strong> lipid-based drug delivery<br />

Outst<strong>and</strong>ing research award<br />

2005 Anette Müllertz, Ph.D.<br />

2006 Russell J. Mumper, Ph.D.<br />

2007 Kishor M. Wasan, Ph.D.<br />

2008 Hayat Onyuksel, Ph.D.<br />

2009 Christopher J.H. Porter, Ph.D.<br />

2011 Ben Boyd, Ph.D.<br />

<strong>aaps</strong> Excellence in lig<strong>and</strong> Binding assays<br />

2004 Jason Pennucci<br />

Steven Swanson, Ph.D.<br />

Shalini Gupta, Ph.D.<br />

2005 Lin Yang<br />

Stephanie Sidobre, Ph.D.<br />

L. Kelly<br />

C. Cooper<br />

M. Khan<br />

2006 F. Nabbie<br />

S. Chang<br />

G. Schieven<br />

R. Zhang<br />

J. Kelsey<br />

R. Weiner<br />

Y. Barrett<br />

2007 Joan Kelsey<br />

2008 Daniel J. Baltrukonis<br />

Thomas Kawabata<br />

Deborah Finco-Kent<br />

2009 Susan Jacques<br />

Shalini Gupta<br />

Steve Swanson<br />

Arunan Kaliyaperumal<br />

2010 Ray Yin<br />

Yli Vallejo<br />

Jing Pan<br />

Thomas Small<br />

Dujie Qin<br />

Dave Chen<br />

2011 Murli Krishna<br />

Alex<strong>and</strong>er Kozhich<br />

Suk Kwok<br />

Zhen Lou<br />

Paul Rhyne<br />

<strong>2012</strong> Jay Wustner<br />

MaryLou Dula<br />

Shawn Fern<strong>and</strong>o<br />

Katie Bendas<br />

Yun Liu<br />

Danielle Horgan<br />

Dan Hanrahan<br />

Megan Kuc<br />

Dongzhao Chen<br />

Michael Deitrich<br />

Estie VanVolkenburgh<br />

Reannon Holl<strong>and</strong><br />

Wolfgang Ebel<br />

Philip Sass<br />

Nicholas Niclaides<br />

<strong>2012</strong> AAPS Annual Meeting <strong>and</strong> <strong>Exposition</strong> 29


<strong>aaps</strong> awards HIsTOrY<br />

<strong>aaps</strong> meritorious manuscript award<br />

1990 Bradley D. Anderson, Ph.D.<br />

Prakash V. Raykar, Ph.D.<br />

Man-Cheong Fung, Ph.D.<br />

1991 Ronald T. Borchardt, Ph.D.<br />

Kevin R. Smith<br />

1992 Noboru Yata, Ph.D.<br />

Toshihiko Toyoda, Ph.D.<br />

Teruo Murakami, Ph.D.<br />

Akio Nishiura, Ph.D.<br />

Yutaka Higashi, Ph.D.<br />

1994 Philip S. Burton, Ph.D.<br />

Robert A. Conradi, Ph.D.<br />

Allen R. Hilgers<br />

Norman F.H. Ho, Ph.D.<br />

1995 P.K. Tsai, Ph.D.<br />

David B. Volkin, Ph.D.<br />

Jonathan M. Dabora<br />

Karen C. Thompson, Ph.D.<br />

Mark W. Bruner<br />

Jacqueline O. Gress<br />

Bozena Matuszewska, Ph.D.<br />

Martina Keogan<br />

Joseph V. Bondi, Ph.D.<br />

C. Russell Middaugh, Ph.D.<br />

1996 Akira Tsuji, Ph.D.<br />

Tetsuya Terasaki, Ph.D.<br />

Ikumi Tamai, Ph.D.<br />

Hitomi Takanaga, Ph.D.<br />

1997 William M. Pardridge, M.D.<br />

Young Sook Kang, Ph.D.<br />

Jody L. Buciak<br />

Jing Yang<br />

1998 Manoj M. Nerurkar, Ph.D.<br />

Philip S. Burton, Ph.D.<br />

Ronald T. Borchardt, Ph.D.<br />

1999 Zheng Yang, Ph.D.<br />

Richard C. Brundage, Ph.D., Pharm.D.<br />

Rashmi H. Barbhaiya, Ph.D.<br />

Ronald J. Sawchuk, Ph.D.<br />

2000 Ahmed El-Tahtawy<br />

Thomas Tozer, Ph.D.<br />

Ferrin Harrison<br />

Larry Lesko, Ph.D.<br />

Roger Williams, M.D.<br />

2001 Neville M. Concessio<br />

Michiel M. Van Oort, Ph.D.<br />

Michael R. Knowles<br />

Anthony J. Hickey, Ph.D.<br />

2002 Cynthia Brimer Cline<br />

James T. Dalton, Ph.D.<br />

Zixon Zhu<br />

John Schuetz, Ph.D.<br />

Kazuto Yasuda<br />

Elio Vanin<br />

Mary V. Relling, Pharm.D.<br />

Yi Lu<br />

Erin G. Schuetz<br />

2003 Wiliam M. Pardridge, M.D.<br />

Ruben J. Boado<br />

Ningya Shi<br />

30<br />

Awards Program<br />

2004 Duxin Sun<br />

Hans Lennernäs, Ph.D.<br />

Lynda S. Welage, Pharm D., FCCP<br />

Jeffery L. Barnett<br />

Christopher P. L<strong>and</strong>owski<br />

David Foster<br />

David Fleisher, Ph.D.<br />

Kyung-Dall Lee, Ph.D.<br />

Gordon L. Amidon, Ph.D.<br />

2005 Per Artusson, Ph.D.<br />

Saeho Chong, Ph.D.<br />

Rick Morrison, Ph.D.<br />

Lauri Söderberg<br />

Jan Taipalensuu<br />

Staffan Tavelin<br />

2006 Jennifer Smith<br />

Edward Wood<br />

Michael Dornish<br />

2007 Goldie Kaul<br />

Mansoor M. Amiji, Ph.D.<br />

2008 William J. Jusko<br />

Zhenling Yao<br />

Debra C. DuBois<br />

Richard R. Almon<br />

<strong>aaps</strong> pharmaceutical research meritorious<br />

manuscript award (formerly <strong>aaps</strong><br />

meritorious manuscript award)<br />

2009 Gary M. Pollack, Ph.D.<br />

John C. Kalvass<br />

2010 Tetsuya Terasaki<br />

Junichi Kamiie<br />

Sumio Ohtsuki<br />

Ryo Iwase<br />

Ken Ohmine<br />

Yuki Katsukura<br />

Kazunari Yanai<br />

Yumi Sekine<br />

Yasuo Uchida<br />

Shingo Ito<br />

2011 Par Matsson<br />

Jenny M. Pedersen<br />

Ulf Norinder<br />

Christel A.S. Bergstrom<br />

Per Artursson<br />

<strong>2012</strong> David E. Alonzo, Ph.D.<br />

Ge<strong>of</strong>f G.Z. Zhang, Ph.D.<br />

Deliang Zhou, Ph.D.<br />

Yi Gao, Ph.D.<br />

Lynne S. Taylor, Ph.D.<br />

<strong>aaps</strong> Outst<strong>and</strong>ing Educator award<br />

2000 Patrick P. DeLuca, Ph.D.<br />

2002 George Zografi, Ph.D.<br />

2004 Larry L. Augsburger, Ph.D.<br />

2006 Joseph B. Schwartz, Ph.D.<br />

2008 Adel Sakr, Ph.D.<br />

2010 Raj Suryanarayanan (Sury), Ph.D.<br />

<strong>2012</strong> John L. Neumeyer, Ph.D.


<strong>aaps</strong> Outst<strong>and</strong>ing manuscript award in<br />

analysis <strong>and</strong> pharmaceutical Quality<br />

1997 Perry A. Hailey, Ph.D.<br />

Phil Doherty<br />

Paul Tapsell<br />

Timothy Oliver<br />

Paul K. Aldridge<br />

1998 Keith K. Burton<br />

Jeremy R. Everett<br />

Michael J. Newman<br />

Frank S. Pullen<br />

Don S. Richards<br />

Alistair G. Swanson<br />

1999 Shewan M. Aziz, R.Ph., Ph.D.<br />

Mustafa Yatin, Ph.D.<br />

David R Worthen, R.Ph., MS, DRW<br />

David W. Lipke, Ph.D.<br />

Peter A. Crooks, Ph.D.<br />

2000 Sean X. Peng, Ph.D.<br />

Babul Borah, Ph.D.<br />

Roy L.M. Dobson, Ph.D.<br />

Y. Diana Liu, Ph.D.<br />

Stanislaw Pikul, Ph.D.<br />

2001 Jacob Bongers, Ph.D.<br />

John J. Cummings<br />

Mary Beth Ebert<br />

M. Marcia Federici, Ph.D.<br />

Linden Gledhill, Ph.D.<br />

Dipti Gulati, Ph.D.<br />

George M. Hilliard, Ph.D.<br />

Brian H. Jones<br />

Kwan R. Lee, Ph.D.<br />

Jacek Mozdzanowski, Ph.D.<br />

Michael Naimoli<br />

Sudhir Burman, Ph.D.<br />

2002 Tim Schenk<br />

H. Irth<br />

György Marko-Varga, Ph.D.<br />

L-E. Edholm<br />

U.R. Tjaden<br />

Jan van der Greef<br />

2003 Dannette Hansen-Doolittle, Ph.D.<br />

Dennis O. Scott, Ph.D.<br />

Kenneth W. Otis<br />

Susan M. Lunte, Ph.D.<br />

2004 Ute Gerhard, Ph.D.<br />

Steven Thomas<br />

Russell Mortishire-Smith<br />

2005 Eva Lenz, Ph.D.<br />

Jonathan D. Bright, Ph.D.<br />

Ian D. Wilson, Ph.D.<br />

Andrew Hughes, Ph.D.<br />

Henrik Lindberg, Ph.D.<br />

Andrew J. Locton, Ph.D.<br />

2006 Peter L.D. Wildfong<br />

Nicole A. Morley<br />

Michael D. Moore<br />

Kenneth R. Morris, Ph.D.<br />

<strong>aaps</strong> awards HIsTOrY<br />

2007 Bryan H. Huynh<br />

Barbara A. Fogarty<br />

Prady<strong>of</strong> N<strong>and</strong>i<br />

Susan M. Lunte, Ph.D.<br />

2008 Yuerong Hu<br />

Håkan Wikström<br />

Stephen R. Byrn<br />

Lynne S. Taylor<br />

2009 Kyung H. Gahm<br />

Helming Tan<br />

Jodi Liu<br />

Wesley Barnhart<br />

John Eschelbach<br />

Steve Notari<br />

Samuel Thomas<br />

David Semin<br />

Janet Cheetham<br />

<strong>2012</strong> Raj Suryanarayanan, Ph.D.<br />

Kapildev K. Arora, Ph.D.<br />

Nitin G. Tayade, Ph.D.<br />

<strong>aaps</strong> Outst<strong>and</strong>ing manuscript award<br />

in PharmSciTech (formerly Outst<strong>and</strong>ing<br />

manuscript in pharmaceutical development<br />

<strong>and</strong> Technology)<br />

1998 Srinivas S. Duggirala, Ph.D.<br />

Rahul C. Mehta, Ph.D.<br />

Patrick P. DeLuca, Ph.D.<br />

2000 Wei-Qin (Tony)Tong<br />

Graham Whitsell<br />

2002 Janusz W. Kostanski, Ph.D.<br />

Patrick P. DeLuca, Ph.D.<br />

2004 Ch<strong>and</strong>ra Vemavarapu, Ph.D.<br />

Matthew J. Mollan, Ph.D.<br />

Thomas E. Needham, Ph.D.<br />

2006 Susan D’Souza<br />

Jabar Faraj, Ph.D.<br />

Patrick P. DeLuca, Ph.D.<br />

2008 Ambikan<strong>and</strong>an Misra (Lead Author)<br />

Tushar K. Vyas<br />

A.K. Babbar<br />

Rakesh K. Sharma<br />

Shashi Singh<br />

2010 Svetlana Lyapustina<br />

Steven Novick<br />

David Christopher<br />

Monisha Dey<br />

Michael Golden<br />

Stefan Leiner<br />

Bruce Wyka<br />

Hans-Joachim Delzeit<br />

Chris Novack<br />

Gregory Larner<br />

<strong>2012</strong> AAPS Annual Meeting <strong>and</strong> <strong>Exposition</strong> 31


<strong>aaps</strong> awards HIsTOrY<br />

<strong>aaps</strong> Journal manuscript award (formerly<br />

<strong>aaps</strong> PharmSci manuscript award)<br />

2003 Michael H. Qvist<br />

Ulla Hoeck<br />

Bo Kreilgaard, Ph.D.<br />

Flemming Madsen, Ph.D.<br />

Lars Hovgaard, Ph.D.<br />

Sven Frokjaer, Ph.D.<br />

2005 James D. Andya<br />

Chung C. Hsu, Ph.D.<br />

Steven J. Shire, Ph.D.<br />

2007 Siddhesh D. Patil, Ph.D.<br />

David G. Rhodes, Ph.D.<br />

Diane J. Burgess, Ph.D.<br />

2009 Vladimir P. Torchilin, Ph.D.<br />

2011 Ayman El-Sayed<br />

Shiroh Futaki<br />

Hideyoshi Harashima<br />

<strong>aaps</strong> Outst<strong>and</strong>ing manuscript in modeling<br />

<strong>and</strong> simulation award<br />

2008 Kaori Ito<br />

Matt M Hutmacher<br />

Jing Liu<br />

Ruolun Qiu<br />

Bill Frame<br />

Raymond Miller<br />

2009 Dhaval K. Shah<br />

Beom Soo Shin<br />

Jean Veith<br />

Karoly Toth<br />

Ralph J. Bernacki<br />

Joseph P. Balthasar<br />

2010 Eric Snoeck<br />

Karin Jorga<br />

Pascal Chanu<br />

Mark Lavielle<br />

Philippe Jacqmin<br />

E Niclas Jonsson<br />

Timothy Goggin<br />

Joseph Grippo<br />

N. L’ntshotshole Shasha Jumbe<br />

Nicolas Frey<br />

<strong>2012</strong> Paulo Paixão<br />

José A.G. Morais<br />

Luís F. Gouveia<br />

<strong>aaps</strong> PharmSci & <strong>aaps</strong> PharmSciTech<br />

Outst<strong>and</strong>ing use <strong>of</strong> Technology award<br />

2003 Keith D. Jensen<br />

Pavla Kopecková<br />

John H.B. Bridge<br />

Jindrich Kopecek<br />

32<br />

Awards Program<br />

<strong>aaps</strong> new Investigator grant in<br />

pharmaceutics <strong>and</strong> the pharmaceutical<br />

Technologies<br />

1987 Ronald A. Siegel, Sc.D.<br />

1988 Elizabeth Topp, Ph.D.<br />

1989 Ashim K. Mitra, Ph.D.<br />

1990 Anthony J. Hickey, Ph.D.<br />

1991 Timothy S. Wiedmann, Ph.D.<br />

1992 Yongyut Rojanasakul, Ph.D.<br />

1993 Patrick J. Sinko, Ph.D.<br />

1994 Jane Pei-Fan Bai, Ph.D.<br />

1995 Paul M. Bummer, Ph.D.<br />

1996 Susanna Wu-Pong, Ph.D.<br />

1997 Uday B. Kompella, Ph.D.<br />

1998 James E. Polli, Ph.D.<br />

1999 Jeffrey Hughes, Ph.D.<br />

2000 Peter W. Swaan, Ph.D.<br />

2001 Kishor M. Wasan, Ph.D.<br />

2002 Tonglei Li, Ph.D.<br />

2003 Lynne S. Taylor, Ph.D.<br />

2004 Abdul W. Basit, Ph.D.<br />

2005 Christopher J. Roberts<br />

2006 Karen Hapgood, Ph.D.<br />

2007 Hugh D. Smyth, Ph.D.<br />

2008 Changquan (Calvin) Sun, Ph.D.<br />

2009 Yoon Yeo, Ph.D.<br />

2010 Jerry Y. Y. Heng, Ph.D.<br />

2011 Kun Cheng, Ph.D.<br />

<strong>2012</strong> Seungpyo Hong, Ph.D.<br />

<strong>aaps</strong> new Investigator grant in<br />

pharmacokinetics, pharmacodynamics<br />

<strong>and</strong> drug metabolism<br />

1992 Kathleen M. Boje, Ph.D.<br />

1994 An-Ng (Tony) Kong, Ph.D.<br />

1996 Deanna L. Kroetz, Ph.D.<br />

1998 David R. Taft, Ph.D.<br />

2000 Bernd Meibohm, Ph.D.<br />

2002 Lane J. Brunner, Ph.D.<br />

2005 Carolyn A. Fairbanks<br />

2007 Donald E. Mager, Ph.D.<br />

2009 Swati V. Nagar<br />

2011 Patrick Thomas Ronaldson, Ph.D.<br />

<strong>aaps</strong> new Investigator grant in Oral<br />

lipids-based drug delivery systems<br />

1999 Christopher J. H. Porter, Ph.D.<br />

2001 Ijeoma F. Uchegbu, Ph.D.<br />

2002 Xiaochen Gu


<strong>aaps</strong> postdoctoral fellow<br />

1999 Sheri L. Shamblin, Ph.D.<br />

2000 Wolfgang Jacobsen, Ph.D.<br />

2002 Yurong Lai, Ph.D.<br />

2003 Ramapuram Jayach<strong>and</strong>ra Babu<br />

2004 Siddhesh D. Patil, Ph.D.<br />

2005 Vanessa M. D’Souza<br />

2006 Mo Yun<br />

2007 Carolyn Cummins, Ph.D.<br />

Heidi M. Mansour, Ph.D., R.Ph.<br />

2008 Udaya Toti, Ph.D.<br />

2009 Ch<strong>and</strong>rasekar Durairaj, Ph.D.<br />

Christina Kriegel, Ph.D.<br />

2010 Bernard Van Eerdenbrugh, Ph.D.<br />

2011 Limin Shi, Ph.D.<br />

<strong>2012</strong> Courtney Sloan, Ph.D.<br />

<strong>aaps</strong> drug delivery Technology award<br />

2008 John T. Santini, Jr., Ph.D.(Lead<br />

researcher)<br />

Elizabeth Proos<br />

James Prescott, Ph.D.<br />

<strong>aaps</strong> dr. rainer H<strong>of</strong>fman product Through<br />

science award<br />

2008 Gary W. Cleary, Ph.D.<br />

2009 Eugene R. Cooper, Ph.D.<br />

2010 Pr<strong>of</strong>essor Hans E. Junginger, Ph.D.<br />

2011 Francis C. Szoka, Ph.D.<br />

lipid-Based drug delivery graduate<br />

student award<br />

2008 Annalisa Mercuri<br />

Caroline Goddeeris<br />

2009 Mrs. Harisun Yaakob<br />

2010 Hazem Ali<br />

Perrine Pivette<br />

2011 Anne Tungelund Larsen<br />

<strong>2012</strong> Yan Yan Yeap<br />

Outst<strong>and</strong>ing graduate student research<br />

award in pT<br />

2001 Jukka Rantanen<br />

Sian Tiong Lim<br />

Bhas A. Dani<br />

2002 Ch<strong>and</strong>ra S. Vemavarapu<br />

Ge Jiang<br />

Vasu Venkat Sethuraman<br />

2003 Niklas Laitinen<br />

Santos B. Murty<br />

Yong Qiu<br />

2004 Stefano Giovagnoli<br />

Sinjan De<br />

Yoon Yeo<br />

2005 Loice Kikwai-Mutua<br />

Susan D’Souza<br />

Pankaj P. Dayal<br />

<strong>aaps</strong> awards HIsTOrY<br />

2006 Jerry Yong Yew Heng<br />

Preetanshu P<strong>and</strong>ey<br />

2007 Robert J. Garmise<br />

2008 Sabiruddin Mirza<br />

2009 Maike Windbergs<br />

2011 Zhe Wang<br />

<strong>2012</strong> Qi (Tony) Zhou<br />

<strong>aaps</strong> david J.w. grant research award in<br />

physical pharmacy<br />

2009 Stephen R. Byrn, Ph.D.<br />

2011 Lian Yu, Ph.D.<br />

Innovation in nanotechnology<br />

2011 Fu Chen<br />

<strong>2012</strong> Arun Kumar Upadhyay<br />

Innovation in Biotechnology awards<br />

2010 Todd Hager<br />

Hongwei Zhang<br />

Ajit Sharma<br />

Annie De Groot<br />

2011 Kaila Bennett<br />

Matthew R. Durk<br />

Diwakar Shukla<br />

Suzanna Taterewicz<br />

Chenguang Zhou<br />

<strong>2012</strong> Mark Spengler<br />

Payal Agarwal<br />

Sathy V. Balu-Iyer<br />

Shraddha Thakkar<br />

Steven Jay<br />

community service award<br />

2010 Patrick P. DeLuca, Ph.D.<br />

<strong>2012</strong> Joseph W. Polli, Ph.D.<br />

<strong>2012</strong> AAPS Annual Meeting <strong>and</strong> <strong>Exposition</strong> 33


<strong>aaps</strong> fEllOws<br />

a<br />

Moji Christianah Adeyeye, Ph.D.<br />

Akwete Lex Adjei, Ph.D.<br />

Kevin D. Altria, Ph.D.<br />

Arm<strong>and</strong>o J. Aguiar, Ph.D.<br />

Michael J. Akers, Ph.D.<br />

Kenneth S. Albert, Ph.D.<br />

S<strong>and</strong>ra R.B. Allerheiligen, Ph.D.<br />

Gordon L. Amidon, Ph.D.<br />

Gregory E. Amidon, Ph.D.<br />

Mansoor M. Amiji, Ph.D.<br />

Bradley D. Anderson, Ph.D.<br />

James B. Appino, Ph.D.<br />

Daniel W. Armstrong, Ph.D.<br />

Per Artursson, M Sci Pharm,<br />

Ph.D.<br />

Okezie I. Aruoma, Ph.D., DSc<br />

Jessie L-S. Au, Ph.D.<br />

Kenneth L. Audus, Ph.D.<br />

Larry L. Augsburger, Ph.D.<br />

Patrick Augustijns, Ph.D.<br />

Michael E. Aulton, Ph.D.<br />

Bruce Aungst, Ph.D.<br />

Kenneth E. Avis, D.Sc.<br />

James W. Ayres, Ph.D.<br />

Daniel L. Azarn<strong>of</strong>f, M.D.<br />

B<br />

You Bae, Ph.D<br />

Steven W. Baertschi, Ph.D.<br />

Marcel Bally, Ph.D.<br />

Joseph P. Balthasar, Ph.D.<br />

Ajay K. Banga, Ph.D.<br />

Gilbert S. Banker, Ph.D.<br />

Rashmi H. Barbhaiya, Ph.D.<br />

Thomas J. Bardos, Ph.D.<br />

William H. Barr, Ph.D.<br />

Jeffrey S. Barrett, Ph.D.<br />

Brian W. Barry, Ph.D.<br />

Herbert Barry, III, Ph.D.<br />

Michael G. Bartlett, Ph.D.<br />

Theodore R. Bates, Ph.D.<br />

Vijay K. Batra, Ph.D.<br />

Charan R. Behl, Ph.D.<br />

Ihor Bekersky, Ph.D.<br />

Reina Bendayan, Pharm.D.<br />

Leslie Z. Benet, Ph.D.<br />

Simon Benita, Ph.D.<br />

Terry L. Benney, Ph.D.<br />

Jean Pierre Benoit, Ph.D.<br />

Richard F. Bergstrom, Ph.D.<br />

William F. Beyer<br />

Meir Bialer, Ph.D.<br />

John A. Biles, Ph.D.<br />

Ian A. Blair, Ph.D.<br />

James Blanchard, Ph.D.<br />

34<br />

Awards Program<br />

Lawrence H. Block, Ph.D.<br />

Robert A. Blouin, Pharm.D.<br />

Nicholas S. Bodor, Ph.D.<br />

Judy P. Boehlert, Ph.D.<br />

Sanford M. Bolton, Ph.D.<br />

Peter L. Bonate, Ph.D., FCP<br />

J. Lyle Bootman, Ph.D.<br />

Ronald T. Borchardt, Ph.D.<br />

F. Douglas Boudinot, Ph.D.<br />

Ronald R. Bowsher, Ph.D<br />

Harold G. Boxenbaum, Ph.D.<br />

James C. Boylan, Ph.D.<br />

Douwe D. Breimer, Ph.D.<br />

Marcus E. Brewster, III, Ph.D.<br />

Harry G. Brittain, Ph.D.<br />

Marvin A. Brooks, Ph.D.<br />

Kim L.R. Brouwer, Ph.D.<br />

Robert W. Brueggemier, Ph.D.<br />

Graham Buckton, Ph.D.<br />

David E. Bugay, Ph.D.<br />

Hans Bundgaard<br />

Diane J. Burgess, Ph.D.<br />

Philip S. Burton, Ph.D.<br />

Louis Busse, Ph.D.<br />

Stephen R. Byrn, Ph.D.<br />

Peter R. Byron, Ph.D.<br />

c<br />

Donald E. Cadwallader, Ph.D.<br />

Henry C. Caldwell, Ph.D.<br />

Carla M. Caramella, Pharm. D.<br />

John R. Cardinal, Ph.D.<br />

David P. Carew, Ph.D.<br />

John F. Carpenter, Ph.D.<br />

C. Jelleff Carr, Ph.D.<br />

Frank I. Carroll, Ph.D.<br />

Jens T. Carstensen, Ph.D.<br />

John M. Cassady, Ph.D.<br />

Lindley A. Cates, Ph.D.<br />

Mitchell N. Cayen, Ph.D.<br />

Lester Chafetz, Ph.D.<br />

Hak-Kim Chan, Ph.D.<br />

Keith K.H. Chan, Ph.D.<br />

Kenneth K. Chan, Ph.D.<br />

William N. Charman, Ph.D.<br />

Mei-Ling Chen, Ph.D.<br />

Yie W. Chien, Ph.D.<br />

Win L. Chiou, Ph.D.<br />

Zak T. Chowhan, Ph.D.<br />

Alex<strong>and</strong>er H.C. Chun, Ph.D.<br />

Alice M. Clark, Ph.D.<br />

Gary W. Cleary, Ph.D.<br />

Jeffrey L. Clel<strong>and</strong>, Ph.D.<br />

Jordan L. Cohen, Ph.D.<br />

Wayne A. Colburn, Ph.D.<br />

Paolo Colombo, Pharm.D.<br />

Kenneth A. Connors, Ph.D.<br />

Panayiotis P. Constantinides,<br />

Ph.D.<br />

Ubaldo Conte, Pharm.D.<br />

Chyung S. Cook, Ph.D.<br />

Stephen J. Coons, Ph.D.<br />

Ge<strong>of</strong>frey A. Cordell, Ph.D.<br />

Raymond E. Counsell, Ph.D.<br />

Ronald T. Coutts, Ph.D.<br />

John C. Craig, Ph.D.<br />

Daan J.A. Crommelin, Ph.D.<br />

Peter A. Crooks, Ph.D.<br />

William G. Crouthamel, Ph.D.<br />

William Curatolo, Ph.D.<br />

Robert W. Curley, Jr., Ph.D.<br />

d<br />

David Z. D’Argenio, Ph.D.<br />

Richard N. Dalby, Ph.D.<br />

James T. Dalton, Ph.D.<br />

Meindert Danh<strong>of</strong>, Ph.D.<br />

Alekha K. Dash<br />

Stanley S. Davis, Ph.D.<br />

Patrick P. DeLuca, Ph.D.<br />

Hartmut Derendorf, Ph.D.<br />

Karl A. DeSante, Ph.D.<br />

J. Arthur de Silva, Ph.D.<br />

Melgardt M. de Villiers, Ph.D.<br />

George A. Digenis, Ph.D.<br />

Shrikant V. Dighe, Ph.D.<br />

Lewis W. Dittert, Ph.D.<br />

James T. Doluisio, Ph.D.<br />

Thomas D. Doyle, Ph.D.<br />

Jennifer B. Dressman, Ph.D.<br />

Dominique Duchêne, Ph.D.<br />

Robert N. Duvall, Ph.D.<br />

E<br />

Natalie D. Eddington, Ph.D.<br />

Gertrude B. Elion, M.S.<br />

William F. Elmquist, Ph.D.<br />

Laszlo Endrenyi, Ph.D.<br />

Ene Ette, Ph.D.<br />

William E. Evans, Pharm.D.<br />

f<br />

Stephen J. Farr, Ph.D.<br />

Reza Fassihi, Ph.D.<br />

Richard E. Faust, Ph.D.<br />

Stuart Feldman, Ph.D.<br />

Edward G. Feldmann, Ph.D.<br />

Anthony F. Fell, Ph.D.<br />

Bobbe L. Ferraiolo, Ph.D.<br />

John W.A. Findlay, Ph.D.<br />

Kenneth Finger, Ph.D.<br />

Joseph A. Fix, Ph.D.


Douglas Flanagan, Jr., Ph.D.<br />

Joseph C. Fleishaker, Ph.D<br />

Alex<strong>and</strong>er T. Florence, Ph.D.,<br />

D.Sc.<br />

Klaus G. Florey, Ph.D.<br />

Gordon L. Flynn, Ph.D.<br />

Dale E. Fonner, Ph.D.<br />

Arlington A. Forist, Ph.D.<br />

William O. Foye, Ph.D.<br />

Sylvan G. Frank, Ph.D.<br />

Ho-Leung Fung, Ph.D.<br />

g<br />

Jean P. Gagnon, Ph.D.<br />

Ping Gao, Ph.D.<br />

Andrea Gazzaniga, Ph.D.<br />

Hamid Gh<strong>and</strong>ehari, Ph.D.<br />

Kathleen M. Giacomini, Ph.D.<br />

Milo Gibaldi, Ph.D.<br />

Carol A. Gl<strong>of</strong>f, Ph.D.<br />

Morton E. Goldberg, Ph.D.<br />

Wayne R. Gombotz, Ph.D.<br />

Igor Gonda, Ph.D.<br />

Frank W. Goodhart, Ph.D.<br />

Jere E. Goyan, Ph.D.<br />

Lee T. Grady, Ph.D.<br />

G. Richard Granneman, Ph.D.<br />

David J. W. Grant, D.Phil.<br />

Thaddeus Grasela, Pharm.D,<br />

Ph.D.<br />

Gregory Gregoriadis, Ph.D.<br />

Michael J. Groves, Ph.D.<br />

Gary L. Grunewald, Ph.D.<br />

J. Keith Guillory, Ph.D.<br />

Robert Gurny, Ph.D.<br />

Richard H. Guy, Ph.D.<br />

H<br />

Jonathan Hadgraft, D.Sc.<br />

Michael J. Hageman, Ph.D.<br />

Jerome A. Halperin, M.S.<br />

Margareta Hammarlund-<br />

Udenaes, Ph.D.<br />

Robert W. Hammel, Ph.D.<br />

Manabu Hanano, Ph.D.<br />

Bruno C. Hancock, Ph.D.<br />

Justin Hanes, Ph.D.<br />

Mitsuru Hashida, Ph.D.<br />

William L. Hayton, Ph.D.<br />

Kenneth R. Heimlich, Ph.D.<br />

Jorge Heller, Ph.D.<br />

William M. Heller, Ph.D.<br />

Stanley L. Hem, Ph.D.<br />

Jack D. Henion, Ph.D.<br />

Piet Herdewijn, Ph.D.<br />

Anthony J. Hickey, Ph.D.<br />

Everett N. Hiest<strong>and</strong>, Ph.D.<br />

Takeru Higuchi, Ph.D.<br />

William I. Higuchi, Ph.D.<br />

A. Atilla Hincal, Ph.D.<br />

Gilbert J. Hite, Ph.D.<br />

Norman F.H. Ho, Ph.D.<br />

Rodney J.Y. Ho. Ph.D.<br />

Stephen W. Hoag, Ph.D.<br />

Guenther Hochhaus, Ph.D.<br />

Irwin L. Honigberg, Ph.D.<br />

Ryohei Hori, Ph.D.<br />

Zola P. Horovitz, Ph.D.<br />

Ken-ichi Hosoya, Ph.D.<br />

Richard A. Houghten, Ph.D.<br />

Oliver Hu, Ph.D.<br />

Jin-Ding Huang, Ph.D.<br />

Leaf Huang, Ph.D.<br />

Shiew-Mei Huang, Ph.D.<br />

Charles D. Hufford, Ph.D.<br />

C. Anthony Hunt, Ph.D.<br />

Ajaz Hussain, Ph.D.<br />

Anwar Hussain, Ph.D.<br />

Munir A. Hussain, Ph.D.<br />

I<br />

Lisbeth Illum, Ph.D., D.Sc.<br />

Ken-ichi Inui, Ph.D.<br />

J<br />

Fakhreddin Jamali, Ph.D.<br />

Bhaskara R. Jasti, Ph.D.<br />

Michael Jay, Ph.D.<br />

Roger Jelliffe, Ph.D.<br />

Mohammed Jemal, Ph.D.<br />

Lee Jia, Ph.D.<br />

Jan H.G. Jonkman, Ph.D.<br />

Robert S. Joslin, Ph.D.<br />

Hans E. Junginger, Ph.D.<br />

William J. Jusko, Ph.D.<br />

K<br />

Peter F. Kador<br />

James J. Kaminski, Ph.D.<br />

Isadore Kanfer, Ph.D.<br />

Stanley A. Kaplan, Ph.D.<br />

Aziz Karim, Ph.D.<br />

Howard T. Karnes, Ph.D.<br />

Martin Katz, Ph.D.<br />

Yoshiaki Kawashima, Ph.D.<br />

Ian W. Kellaway, D.Sc.<br />

Richard A. Kenley, Ph.D.<br />

Mansoor A. Khan, Ph.D.<br />

Lemont B. Kier, Ph.D.<br />

Dane O. Kildsig, Ph.D.<br />

Peter Kleinebudde, Ph.D.<br />

<strong>aaps</strong> fEllOws<br />

Chong-Kook Kim, Ph.D.<br />

Richard B. Kim, M.D.<br />

Sung W. Kim, Ph.D.<br />

A. Douglas Kinghorn, Ph.D.<br />

Arlyn W. Kinkel, Ph.D.<br />

William J. Kinnard, Ph.D.<br />

Peter T. Kissinger, Ph.D.<br />

David A. Knapp, Ph.D.<br />

Joseph E. Knapp, Ph.D.<br />

Adelbert M. Knevel, Ph.D.<br />

Edwin L. Knoechel, Ph.D<br />

Bozena (Bo) Michniak-Kohn,<br />

Ph.D.<br />

Ah-Ng Kong, Ph.D.<br />

Uday Kompella, Ph.D.<br />

Jindrich Kopecek, Ph.D.<br />

Harry B. Kostenbauder, Ph.D.<br />

Jeffrey Kotzan, Ph.D.<br />

Jorg W.R. Kreuter, Ph.D.<br />

Rajesh Krishna, Ph.D., FCP<br />

Patricia D. Kroboth, Ph.D.<br />

Deanna Kroetz, Ph.D.<br />

Roy Kuramoto, Ph.D.<br />

King Chiu Kwan, Ph.D.<br />

Glen S. Kwon, Ph.D.<br />

l<br />

Vinod Labhasetwar, Ph.D.<br />

Leon Lachman, Ph.D.<br />

Richard L. LaLonde, Pharm.D.<br />

Robert S. Langer, Sc.D.<br />

Peter R. Langguth, Ph.D.<br />

Andrew Lasslo, Ph.D.<br />

Thomas P. Layl<strong>of</strong>f, Ph.D.<br />

Jean W. Lee, Ph.D.<br />

Kang Choon Lee, Ph.D.<br />

Vincent H.L. Lee, Ph.D.<br />

Kuo-Hsiung Lee, Ph.D.<br />

Lewis J. Leeson, Ph.D.<br />

Claus-Michael Lehr, Ph.D.<br />

August P. Lemberger, Ph.D.<br />

Hans Lennernäs, Ph.D.<br />

Lawrence J. Lesko, Ph.D.<br />

Hans Leuenberger, Ph.D.<br />

Ralph S. Levi, Ph.D.<br />

Gerhard Levy, Pharm.D.<br />

Rene H. Levy, Ph.D.<br />

Xiaoling Li, Ph.D.<br />

Jiunn Huei Lin, Ph.D.<br />

Thorsteinn L<strong>of</strong>tsson, Ph.D.<br />

Ti Li Loo, D.Sc.<br />

Nicholas G. Lordi, Ph.D.<br />

Ole J. Lorenzetti, Ph.D.<br />

Donghao Robert Lu, Ph.D.<br />

Thomas M. Ludden, Ph.D.<br />

Craig Lunte, Ph.D.<br />

<strong>2012</strong> AAPS Annual Meeting <strong>and</strong> <strong>Exposition</strong> 35


<strong>aaps</strong> fEllOws<br />

Susan M. Lunte, Ph.D.<br />

Louis A. Luzzi, Ph.D.<br />

m<br />

Thomas J. Macek, Ph.D.<br />

Panos E. Macheras, Ph.D.<br />

Ram I. Mahato, Ph.D.<br />

Alex<strong>and</strong>ros Makriyannis, Ph.D.<br />

A. Waseem Malick, Ph.D.<br />

Louis Malspeis, Ph.D.<br />

Tarun K. M<strong>and</strong>al, Ph.D.<br />

Mark C. Manning, Ph.D.<br />

Arnold D. Marcus, Ph.D.<br />

Keith Marshall, Ph.D.<br />

Tobias Massa, Ph.D.<br />

Bogdan K. Matuszewski, Ph.D.<br />

Michael Mayersohn, Ph.D.<br />

William F. McGhan, Ph.D.<br />

Iain J. McGilveray, Ph.D.<br />

James W. McGinity, Ph.D.<br />

Gordon McKay, Ph.D.<br />

Jerry L. McLaughlin, Ph.D.<br />

Patrick J. McNamara, Ph.D.<br />

Thomas Medwick, Ph.D.<br />

Mehul U. Mehta, Ph.D.<br />

Bernd Meibohm, Ph.D.<br />

Srikumaran K. Melethil, Ph.D.,<br />

J.D.<br />

Hans Peter Merkle, Ph.D.<br />

Carl M. Metzler, Ph.D.<br />

Marvin C. Meyer, Ph.D.<br />

C. Russell Middaugh, Ph.D.<br />

Kamal K. Midha, D.Sc.<br />

Duane D. Miller, Ph.D.<br />

Raymond Miller, D.Sc.<br />

Tamara Minko, Ph.D.<br />

Hyman Mitchner, Ph.D.<br />

Ashim K. Mitra, Ph.D.<br />

Tom S. Miya, Ph.D.<br />

Arthur R. Mlodozeniec, Ph.D.<br />

Marilyn M. Martinez, Ph.D.<br />

Henry I. Mosberg<br />

Anthony C. M<strong>of</strong>fat, Ph.D.<br />

Joyce J. Mordenti, Ph.D.<br />

Kenneth R. Morris, Ph.D.<br />

Marilyn E. Morris, Ph.D.<br />

Daniel Mufson, Ph.D.<br />

Pasupati Mukerjee, Ph.D.<br />

Russell J. Mumper, Ph.D.<br />

Eric J. Munson, Ph.D.<br />

Ram B. Murty, Ph.D.<br />

36<br />

Awards Program<br />

n<br />

Tsuneji Nagai, Ph.D.<br />

Steven L. Nail, Ph.D.<br />

Masahiro Nakano, Ph.D.<br />

Moheb M. Nasr, Ph.D.<br />

Kenneth G. Nelson, Ph.D.<br />

Wendel L. Nelson, Ph.D.<br />

John L. Neumeyer, Ph.D.<br />

Tue H. Nguyen, Ph.D.<br />

David E. Nichols, Ph.D.<br />

G. Joseph Norwood, Ph.D.<br />

Robert E. Notari, Ph.D.<br />

O<br />

Derek T. O’Hagan, Ph.D.<br />

Bernard A. Olsen, Ph.D.<br />

Hayat Onyuksel, Ph.D.<br />

Masaki Otagiri, Ph.D.<br />

p<br />

Kim-Ching (S<strong>and</strong>y) Pang, Ph.D.<br />

Gerald J. Papariello, Ph.D.<br />

Kinam Park, Ph.D.<br />

Eugene L. Parrott, Ph.D.<br />

Dev S. Pathak, D.B.A.<br />

Thomas F. Patton, Ph.D.<br />

Rodney Pearlman, Ph.D.<br />

Carl C. Peck, M.D.<br />

Garnet E. Peck, Ph.D.<br />

Nicholas A. Peppas, Sc.D.<br />

Bengt-Arne Persson, Ph.D.<br />

Claude Piantadosi, Ph.D.<br />

Henry J. Pieniaszek, Jr., Ph.D.<br />

Michael J. Pikal, Ph.D.<br />

Ian H. Pitman, Ph.D.<br />

Fridrun Podczeck, Dr. sc. nat.<br />

habil.<br />

Gary M. Pollack, Ph.D.<br />

James E. Polli, Ph.D.<br />

Joseph W. Polli, Ph.D<br />

John W. Poole, Ph.D.<br />

Emil Pop, Ph.D.<br />

David G. Pope, Ph.D.<br />

Philip S. Portoghese, Ph.D.<br />

Russell O. Potts, Ph.D.<br />

Boyd J. Poulsen, Ph.D.<br />

Colin W. Pouton, Ph.D.<br />

J. Robert Powell, Ph.D.<br />

Michael F. Powell, Ph.D.<br />

Vadlamani K. Prasad, Ph.D.<br />

Thomayant Prueksaritanont,<br />

Ph.D.<br />

William P. Purcell, Ph.D.<br />

Q<br />

Yihong Qiu, Ph.D.<br />

r<br />

Galen W. Radebaugh, Ph.D.<br />

Yueh-Erh Rahman, M.D.<br />

Theodore R<strong>and</strong>olph, Ph.D.<br />

Rao S. Rapaka, Ph.D.<br />

Louis J. Ravin, Ph.D.<br />

Indra K. Reddy, Ph.D.<br />

Robert A. Reed, Ph.D.<br />

Gurvinder Singh Rekhi, Ph.D.<br />

Jean Paul Remon, Ph.D.<br />

Michael A. Repka, Ph.D.<br />

A.J. Repta, Ph.D.<br />

Richard H. Reuning, Ph.D.<br />

Christopher T. Rhodes, Ph.D.<br />

Kenner C. Rice, Ph.D.<br />

Christopher M. Riley, Ph.D.<br />

Edward G. Rippie, Ph.D.<br />

Wolfgang A. Ritschel, M.D.,<br />

Ph.D.<br />

Joseph R. Robinson, Ph.D.<br />

Christopher A. Rodowskas<br />

A. David Rodrigues, Ph.D.<br />

Yongyut Rojanasakul, Ph.D<br />

Alain Roll<strong>and</strong>, Ph.D.<br />

Theodore J. Roseman, Ph.D.<br />

Amy Rosenberg, M.D.<br />

Carlo Rossi, Pharm.D.<br />

Malcolm Rowl<strong>and</strong>, Ph.D.<br />

Frans G.M. Russel, Ph.D.<br />

Emanuel J. Russo, Ph.D.<br />

Charles O. Rutledge, Ph.D.<br />

J. Howard Rytting, Ph.D.<br />

s<br />

M<strong>and</strong>ip S. Sachdeva, Ph.D.<br />

Wolfgang Sadée, Ph.D.<br />

A. Adel Sakr, Ph.D.<br />

Lynda M. S<strong>and</strong>ers, Ph.D.<br />

Ronald J. Sawchuk, Ph.D.<br />

Jerome J. Schentag, Pharm.D.<br />

Jean-Michel G. Scherrmann,<br />

Pharm.D., Ph.D.<br />

Paul L. Schiff, Jr., Ph.D.<br />

Peter Wilhelm Schiller, Ph.D.<br />

George Schneller, Ph.D.<br />

Christian Schöneich, Ph.D.<br />

Joseph B. Schwartz, Ph.D.<br />

Michael A. Schwartz, Ph.D.<br />

John J. Sciarra, Ph.D.<br />

James A. Seitz, Ph.D.<br />

Bernard Z. Senkowski, Ph.D.


Cosette J. Serabjit-Singh, Ph.D.<br />

Abu Serajuddin, Ph.D.<br />

Hitoshi Sezaki, Ph.D.<br />

Ashok C. Shah, Ph.D.<br />

Navnit H. Shah, Ph.D.<br />

Vinod P. Shah, Ph.D.<br />

Evgenyi Shalaev, Ph.D.<br />

Jane E. Shaw, Ph.D.<br />

Eli Shefter, Ph.D.<br />

Eric B. Sheinin, Ph.D.<br />

John W. Shell, Ph.D.<br />

Danny D. Shen, Ph.D.<br />

Wei-Chiang Shen, Ph.D.<br />

Chang-Koo Shim, Ph.D.<br />

Steven J. Shire, Ph.D.<br />

Teruna Siahaan, Ph.D.<br />

Ronald A. Siegel, Sc.D.<br />

Jeffrey A. Silverman, Ph.D.<br />

Anthony P. Simonelli, Ph.D.<br />

Jagdish Singh, Ph.D.<br />

Manmohan Singh, Ph.D.<br />

Sampat M. Singhvi, Ph.D.<br />

Patrick J. Sinko, Ph.D.<br />

Anthony A. Sinkula, Ph.D.<br />

John A. Sjögren, Ph.D.<br />

Jerome P. Skelly, Ph.D.<br />

John T. Slattery, Ph.D.<br />

David E. Smith, Ph.D.<br />

Edward Smith, Ph.D.<br />

Mickey C. Smith, Ph.D.<br />

Philip L. Smith, Ph.D.<br />

R<strong>and</strong>all B. Smith, Ph.D.<br />

Quentin Smith, Ph.D.<br />

Robert V. Smith, Ph.D.<br />

Theodore D. Sokoloski, Ph.D.<br />

Albert H. Soloway, Ph.D.<br />

Marilyn K. Speedie, Ph.D.<br />

John Staniforth, Ph.D.<br />

Salomon A. Stavchansky, Ph.D.<br />

Valentino J. Stella, Ph.D.<br />

Larry A. Sternson, Ph.D.<br />

James T. Stewart, Ph.D.<br />

Clinton Fields Stewart,<br />

Pharm.D.<br />

Audra Stinchcomb, Ph.D.<br />

John F. Stobaugh, Ph.D.<br />

Robert M. Straubinger, Ph.D.<br />

Heinz B. Sucker, Ph.D.<br />

Yuichi Sugiyama, Ph.D.<br />

Raj Suryanaryanan, Ph.D.<br />

Steven C. Sutton, Ph.D.<br />

Hiroshi Suzuki, Ph.D.<br />

Craig K. Svensson, Ph.D.<br />

Peter W. Swaan, Ph.D.<br />

Steven J. Swanson, Ph.D.<br />

James Swarbrick, Ph.D.<br />

Joseph V. Swintosky, Ph.D.<br />

Francis C. Szoka, Jr., Ph.D.<br />

T<br />

Yoshinobu Takakura, Ph.D.<br />

Vijay K. Tamarra, Ph.D.<br />

Diane D-S. Tang-Liu, Ph.D.<br />

Rashad Tawashi, Ph.D.<br />

Lynne S. Taylor, Ph.D.<br />

David H. Tedeschi, Ph.D.<br />

Tetsuya Terasaki, Ph.D.<br />

Bernard J. Testa, Ph.D.<br />

Dhiren R. Thakker, Ph.D.<br />

Felix Theeuwes, Ph.D.<br />

Gary A. Thompson, Ph.D.<br />

Kenneth E. Thummel, Ph.D.<br />

Alice E. Till, Ph.D.<br />

William J. Tillman, Ph.D.<br />

James E. Tingstad, Ph.D.<br />

Eric Tomlinson, Ph.D.<br />

Elizabeth M. Topp, Ph.D.<br />

Vladimir P. Torchilin, Ph.D.,<br />

D.Sc.<br />

Thomas N. Tozer, Ph.D.<br />

Timothy S. Tracy, Ph.D.<br />

Francis L.S. Tse, Ph.D.<br />

Akira Tsuji, Ph.D.<br />

Varro E. Tyler, Ph.D.<br />

u<br />

Kaneto Uekama, Ph.D.<br />

Jashvant D. Unadkat, Ph.D.<br />

Sathyanarayana M.<br />

Upadrashta, Ph.D.<br />

John Urquhart, M.D.<br />

Arto O. Urtti, Ph.D.<br />

V<br />

Elizabeth B. Vadas, Ph.D.<br />

Glen A. Van Buskirk, Ph.D.<br />

Peter Veng-Pedersen, Ph.D.<br />

Jurgen Venitz, Ph.D.<br />

Raman Venkataramanan, Ph.D.<br />

S. Jorgen Vessman, Pharm.D.,<br />

Ph.D.<br />

Paolo Vicini, Ph.D.<br />

C. T. Viswanathan, Ph.D.<br />

w<br />

John A. Wagner, M.D., Ph.D<br />

John G. Wagner, Ph.D.<br />

Irving W. Wainer, Ph.D.<br />

Walter D. Walkling, Ph.D.<br />

<strong>aaps</strong> fEllOws<br />

Jesse W. Wallace<br />

Y. John Wang, Ph.D.<br />

Kishor M. Wasan, Ph.D.<br />

Kenneth Waterman, Ph.D.<br />

Lawrence C. Weaver, Ph.D.<br />

Jeffry G. Weers, Ph.D.<br />

Norman D. Weiner, Ph.D.<br />

Peter G. Welling, Ph.D.<br />

Albert I. Wertheimer, Ph.D.<br />

Joseph Wiederholt, Ph.D.<br />

M. Guillaume Wientjes, Ph.D.<br />

Grant R. Wilkinson, Ph.D.<br />

Roger L. Williams, M.D.<br />

Robert O. Williams, Ph.D.<br />

Robert J. Wills, Ph.D.<br />

Donald T. Witiak, Ph.D.<br />

Manfred E. Wolff, Ph.D.<br />

Hal N. Wolk<strong>of</strong>f, Ph.D.<br />

John H. Wood, Ph.D.<br />

Paul E. Wray, Ph.D.<br />

George Wright, Ph.D.<br />

Dale E. Wurster, Ph.D.<br />

Dale Eric Wurster, Ph.D.<br />

Y<br />

Avraham Yacobi, Ph.D.<br />

Gerald J. Yakatan, Ph.D.<br />

Samuel H. Yalkowsky, Ph.D.<br />

Shinji Yamashita, Ph.D.<br />

Victor C. Yang, Ph.D.<br />

Peter York, Ph.D.<br />

Sumie Yoshioka, Ph.D.<br />

Lawrence X. Yu, Ph.D.<br />

Lian Yu, Ph.D.<br />

Su Il Yum, Ph.D.<br />

Z<br />

Alej<strong>and</strong>ro A. Zaffaroni, Ph.D.<br />

Gaylen M. Zentner, Ph.D.<br />

Ge<strong>of</strong>f G.Z. Zhang, Ph.D.<br />

Chang-Guo Zhan, Ph.D.<br />

Cheryl L. Zimmerman, Ph.D.<br />

George Zografi, Ph.D.<br />

<strong>2012</strong> AAPS Annual Meeting <strong>and</strong> <strong>Exposition</strong> 37


38<br />

Awards Program

Hooray! Your file is uploaded and ready to be published.

Saved successfully!

Ooh no, something went wrong!