2012 aaps annual meeting and Exposition - American Association of ...
2012 aaps annual meeting and Exposition - American Association of ...
2012 aaps annual meeting and Exposition - American Association of ...
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<strong>2012</strong> awards<br />
prOgram<br />
October 14–18, <strong>2012</strong><br />
McCormick Place, Chicago
<strong>2012</strong> <strong>aaps</strong> <strong>annual</strong> <strong>meeting</strong> <strong>and</strong> <strong>Exposition</strong><br />
Sunday, October 14<br />
4:30 pm – 6:30 pm<br />
McCormick Place, Chicago<br />
david Y. mitchell, ph.d.<br />
PreSiding AAPS PreSident<br />
In mEmOrIum<br />
OpEnIng sEssIOn prOgram<br />
The <strong>American</strong><br />
<strong>Association</strong> <strong>of</strong><br />
Pharmaceutical<br />
Scientists (AAPS)<br />
is sad to report the<br />
loss <strong>of</strong> a dear friend<br />
<strong>and</strong> colleague.<br />
AAPS’ fourth<br />
president, James<br />
(Jim) E. Tingstad,<br />
passed away on<br />
November 9, 2011, after a long struggle with<br />
Alzheimer’s disease. Raised in Cook, MN,<br />
<strong>and</strong> Milwaukee, Tingstad served in the U.S.<br />
Army in Korea <strong>and</strong> attended the University<br />
<strong>of</strong> Wisconsin, Madison, where he received<br />
his doctorate in pharmaceutical sciences in<br />
1958. Over the course <strong>of</strong> his life, Tingstad<br />
You are cordially invited to<br />
attend the AAPS Welcome<br />
Reception immediately<br />
following this ceremony. The<br />
reception will take place at the<br />
McCormick Place Convention<br />
Center. Shuttle buses will be<br />
available to transport attendees<br />
to their hotels following the<br />
Opening Session <strong>and</strong> the<br />
Welcome Reception.<br />
held positions at various companies <strong>and</strong><br />
educational institutions including 3M, Abbott<br />
Laboratories, <strong>and</strong> the University <strong>of</strong> California<br />
San Francisco School <strong>of</strong> Pharmacy.<br />
Tingstad’s term as AAPS president was<br />
characterized by growth. The association<br />
saw a huge increase in membership, staff<br />
size, <strong>and</strong> <strong>of</strong>fice facilities during his tenure,<br />
as well as the number <strong>of</strong> sections <strong>and</strong><br />
growth in assets <strong>and</strong> financial security.<br />
Tingstad is survived by his wife Phyllis,<br />
four children, <strong>and</strong> a host <strong>of</strong> gr<strong>and</strong>children,<br />
great-gr<strong>and</strong>children, <strong>and</strong> other family<br />
<strong>and</strong> friends. AAPS remembers Tingstad<br />
<strong>and</strong> will forever remember his contributions<br />
to the association.<br />
<strong>2012</strong> AAPS Annual Meeting <strong>and</strong> <strong>Exposition</strong> 1
OpEnIng sEssIOn prOgram<br />
In mEmOrIum (continued)<br />
dean Emeritus<br />
Joseph V.<br />
swintosky, a<br />
legendary educator<br />
<strong>and</strong> scientist<br />
who helped lead<br />
the University <strong>of</strong><br />
Kentucky College<br />
<strong>of</strong> Pharmacy<br />
to national <strong>and</strong><br />
international<br />
prominence during his tenure as dean from<br />
1967 to 1987, passed away on September 14,<br />
<strong>2012</strong>. He was 90 years old.<br />
Dr. Swintosky, a native <strong>of</strong> Kewaunee County,<br />
Wisconsin, received his bachelor <strong>of</strong> science<br />
degree <strong>and</strong> Ph.D. in pharmacy from the<br />
University <strong>of</strong> Wisconsin. An accomplished<br />
educator, product formulation scientist,<br />
<strong>and</strong> recipient <strong>of</strong> numerous national honors,<br />
a.J.m. (Ton) Hoek<br />
was born in The<br />
Hague, in 1955 <strong>and</strong><br />
studied Pharmacy at<br />
the State University<br />
<strong>of</strong> Leiden in the<br />
Netherl<strong>and</strong>s.<br />
He obtained his<br />
Master <strong>of</strong> Science<br />
degree in 1983 <strong>and</strong><br />
graduated as a pharmacist in 1984. He had<br />
training periods in both the pharmaceutical<br />
practice <strong>and</strong> the hospital pharmacy.<br />
After university Ton Hoek joined the<br />
pharmaceutical industry <strong>and</strong> worked at<br />
several management positions both in R&D<br />
as well as in marketing.<br />
From 1999, Ton Hoek was the General<br />
Secretary <strong>and</strong> Chief Executive Officer <strong>of</strong> FIP,<br />
the International Pharmaceutical Federation.<br />
The FIP is the global federation <strong>of</strong> 127<br />
national organizations <strong>of</strong> pharmacists <strong>and</strong><br />
pharmaceutical scientists, with its mission<br />
to improve global health by: advancing<br />
pharmacy practice <strong>and</strong> science, to enable<br />
2<br />
Awards Program<br />
Dr. Swintosky is probably best known for<br />
his innovative work to transform pharmacy<br />
education <strong>and</strong> the pharmacy pr<strong>of</strong>ession<br />
while at UK.<br />
On January 1, 1967, Dr. Swintosky became<br />
the fourth Dean <strong>of</strong> the UK College <strong>of</strong><br />
Pharmacy <strong>and</strong> created the master’s <strong>and</strong><br />
Ph.D. graduate program, a move that<br />
cemented UK as a national leader in<br />
graduate education <strong>and</strong> pharmaceutical<br />
research. His impact on pharmacy<br />
continues today through the achievements<br />
<strong>of</strong> former faculty <strong>and</strong> graduates who now<br />
are national <strong>and</strong> international leaders,<br />
including at least 10 deans at other colleges.<br />
Dr. Swintosky was a Founder <strong>of</strong> AAPS. He<br />
leaves behind his wife Dorothy, nine sons<br />
<strong>and</strong> one daughter.<br />
better discovery, development, access to<br />
<strong>and</strong> safe use <strong>of</strong> appropriate, cost-effective,<br />
<strong>and</strong> quality medicines worldwide.<br />
Together with his counterparts from<br />
the World Medical <strong>Association</strong> <strong>and</strong> the<br />
International Council <strong>of</strong> Nurses, Hoek has<br />
set up the World Health Pr<strong>of</strong>essions Alliance<br />
(WHPA), a strategic alliance between the<br />
global health pr<strong>of</strong>essional associations<br />
representing physicians, nurses, dentists<br />
<strong>and</strong> pharmacists.<br />
In <strong>2012</strong> Hoek was awarded an Officer in<br />
the Orange-Nassau, a Royal declaration<br />
bestowed by the Queen <strong>of</strong> the Netherl<strong>and</strong>s.<br />
During the awards ceremony for this<br />
prestigious designation he was also<br />
recognised with an honorary resolution<br />
from the <strong>American</strong> Pharmacists <strong>Association</strong><br />
(APhA) citing his active dedication to<br />
pharmacy <strong>and</strong> a joint congratulatory letter<br />
from the APhA, the <strong>American</strong> <strong>Association</strong><br />
<strong>of</strong> Colleges <strong>of</strong> Pharmacy (AACP), the<br />
<strong>American</strong> <strong>Association</strong> <strong>of</strong> Pharmaceutical<br />
Scientists (AAPS) <strong>and</strong> the <strong>American</strong> Society<br />
<strong>of</strong> Health-Systems Pharmacists (ASHP).
<strong>aaps</strong> <strong>2012</strong> ExEcuTIVE cOuncIl<br />
david Y. mitchell, ph.d.<br />
PreSident<br />
philip r. mayer, ph.d.<br />
iMMediAte PASt PreSident<br />
anthony J. destefano, ph.d.<br />
PreSident-eleCt<br />
wayne r. gombotz, ph.d.<br />
treASurer<br />
marilyn E. morris, ph.d. (<strong>2012</strong>)<br />
MeMber-At-lArge<br />
James E. polli, ph.d. (2013)<br />
MeMber-At-lArge<br />
raman Venkataramanan, ph.d. (2013)<br />
MeMber-At-lArge<br />
dannette K. doolittle, ph.d. (2014)<br />
MeMber-At-lArge<br />
russell s. weiner, ph.d. (2014)<br />
MeMber-At-lArge<br />
<strong>2012</strong> AAPS Annual Meeting <strong>and</strong> <strong>Exposition</strong> 3
OpEnIng sEssIOn prOgram<br />
wElcOmIng rEmarKs<br />
John lisack, Jr., caE<br />
exeCutive direCtOr<br />
4<br />
Awards Program<br />
david Y. mitchell, ph.d.<br />
AAPS PreSident<br />
prEsEnTaTIOn <strong>and</strong> rEcOgnITIOn Of all awards<br />
david Y. mitchell, ph.d. leslie Z. Benet, ph.d.<br />
AAPS PreSident univerSity Of CAlifOrniA
spEcIal rEcOgnITIOns<br />
IpEc Excipient graduate<br />
student awards<br />
xi Han<br />
new JerSey inStitute Of teChnOlOgy<br />
grace Ilevbare<br />
Purdue univerSity<br />
sumit Kumar<br />
univerSity Of COnneCtiCut<br />
Ting wang<br />
univerSity Of MArylAnd, bAltiMOre<br />
amit wani<br />
wAyne StAte univerSity<br />
phrma pre doctoral fellowships<br />
in the pharmaceutics<br />
sweta modi<br />
univerSity Of KentuCKy<br />
poonam sheth<br />
univerSity Of ArizOnA<br />
matthew Herpin<br />
univerSity Of texAS At AuStin<br />
phrma research starter grants<br />
in pharmaceutics<br />
Oleh Taratula, ph.d.<br />
OregOn StAte univerSity<br />
afpE minority pre-doctoral fellows<br />
in pharmaceutical science<br />
sophia n. Ononye<br />
univerSity Of COnneCtiCut<br />
award rEcIpIEnTs<br />
<strong>aaps</strong>-afpE pre-doctoral fellows<br />
in the pharmaceutical sciences<br />
Vaishali l. chudasama<br />
univerSity At buffAlO, Suny<br />
caroline a. larregieu<br />
univerSity Of CAlifOrniA, SAn frAnCiSCO<br />
afpE pre-doctoral fellows in clinical<br />
pharmaceutical sciences<br />
daniel J. crona<br />
univerSity Of nOrth CArOlinA<br />
melanie r. nicol<br />
univerSity Of nOrth CArOlinA<br />
<strong>aaps</strong> graduate student symposium<br />
in analysis & pharmaceutical Quality<br />
SPOnSOred by u.S. Pharmacopeia<br />
<strong>and</strong> wolfe labs<br />
McCormick Place Convention Center<br />
room w190A<br />
tuesday, October 16, <strong>2012</strong><br />
8:30 am – 11:00 am<br />
cary mcginnis<br />
univerSity Of geOrgiA<br />
Quantification <strong>and</strong> Characterization<br />
<strong>of</strong> siRNA <strong>and</strong> its Metabolites in<br />
Biological Matrices<br />
<strong>2012</strong> AAPS Annual Meeting <strong>and</strong> <strong>Exposition</strong> 5
award recipients<br />
Khushboo Bakul Kothari<br />
univerSity Of MinneSOtA<br />
Investigating the Role <strong>of</strong> Polymer<br />
Concentration on the Physical Stability <strong>of</strong><br />
Nifedipine-PVP Solid Dispersions<br />
lindsay anne wegiel<br />
Purdue univerSity<br />
Assessment <strong>of</strong> Molecular Drug-polymer<br />
Interactions by Mid-infrared Spectroscopy<br />
as a Polymer Selection Tool for Formulating<br />
Amorphous Solid Dispersions with Optimal<br />
Physical Stability<br />
poonam r. delvadia<br />
virginiA COMMOnweAlth univerSity<br />
High Performance Liquid Chromatographic<br />
Method <strong>and</strong> Selectivity Investigation for the<br />
Analysis <strong>of</strong> Nicotine in Biorelevant Release/<br />
Permeation Studies <strong>of</strong> Smokeless Tobacco<br />
6<br />
Awards Program<br />
<strong>aaps</strong> graduate student symposium<br />
in Biotechnology<br />
SPOnSOred by Pfizer global research<br />
<strong>and</strong> development<br />
McCormick Place Convention Center<br />
room w190b<br />
tuesday, October 16, <strong>2012</strong><br />
8:30 am – 11:00 am<br />
david woessner<br />
univerSity Of utAh<br />
Synthetically Lethal Combinations for CML<br />
Therapy—Disrupting Dimerization <strong>of</strong> Bcr-Abl<br />
<strong>and</strong> Secondary Leukemia Specific Pathways<br />
Jin Huk choi<br />
the univerSity Of texAS At AuStin<br />
Modeling Pre-existing Immunity to<br />
Adenovirus as a Method to Identify Novel<br />
Formulations for a Protective Ebola Vaccine<br />
mamta Kapoor<br />
univerSity Of COnneCtiCut<br />
Elucidation <strong>of</strong> Cellular Uptake Mechanism <strong>of</strong><br />
Novel Ternary Anionic-siRNA Lipoplexes
puneet Tyagi<br />
univerSity Of COlOrAdO<br />
A Highly Potent, Choroid-targeted,<br />
Transferrin-tumstatin Fusion Protein<br />
<strong>and</strong> an In Situ Forming Slow-release<br />
Hydrogel for the Treatment <strong>of</strong> Choroidal<br />
Neovascularization<br />
<strong>aaps</strong> graduate student symposium<br />
in drug discovery <strong>and</strong> development<br />
Interface<br />
SPOnSOred by Allergan, wolfe laboratories,<br />
<strong>and</strong> bristol-Myers Squibb Company<br />
McCormick Place Convention Center<br />
room w185<br />
tuesday, October 16, <strong>2012</strong><br />
8:30 am – 11:00 am<br />
Yumna shabaik<br />
univerSity Of SOuthern CAlifOrniA<br />
Mechanistic Evaluation <strong>of</strong> a Mitochondrialtargeted<br />
Small Molecule as a Novel<br />
Treatment for Pancreatic Cancer<br />
sashikanth Banappagari<br />
the univerSity Of lOuiSiAnA At MOnrOe<br />
Modulation <strong>of</strong> EGF-receptors Signaling by<br />
Small Peptidomimetics <strong>and</strong> its Implications in<br />
Breast Cancer Progression<br />
award recipients<br />
lu xu<br />
univerSity Of the PACifiC<br />
Molecular Docking, Synthesis <strong>of</strong> Novel<br />
Quinazolin Analogues as Inhibitors <strong>of</strong><br />
Transcription Factors NF-kappaB Activation<br />
<strong>and</strong> their Anti-cancer Activities<br />
lakshmi prasanna Kolluru<br />
MerCer univerSity<br />
Design <strong>and</strong> Development <strong>of</strong> Albumin Based<br />
Theragnostic Nanoparticles for Tumor<br />
Targeted Drug Delivery<br />
<strong>aaps</strong> graduate student symposium in<br />
formulation design <strong>and</strong> development<br />
SPOnSOred by bristol-Myers<br />
Squibb Company<br />
McCormick Place Convention Center<br />
room w196<br />
tuesday, October 16, <strong>2012</strong><br />
8:30 am – 12:00 pm<br />
apurva r. patel<br />
flOridA A&M univerSity<br />
Theranostic Tumor Homing Pegylated<br />
Nanocarrier Drug Delivery System for<br />
Treatment <strong>of</strong> Cancer<br />
<strong>2012</strong> AAPS Annual Meeting <strong>and</strong> <strong>Exposition</strong> 7
award recipients<br />
grace a. Ilevbare<br />
Purdue univerSity<br />
Underst<strong>and</strong>ing Polymer Properties Important<br />
for Crystal Growth Inhibition—Impact <strong>of</strong><br />
Chemically Diverse Polymers on Solution<br />
Crystal Growth <strong>of</strong> Ritonavir<br />
Jiban Jyoti p<strong>and</strong>a<br />
f.M. univerSity, OriSSA, indiA<br />
Self-assembled Dipeptide Nanotubes,<br />
Nanovesicles <strong>and</strong> Nanogels: Potential<br />
Vehicles for Targeted Tumor Drug Delivery<br />
<strong>aaps</strong> graduate student symposium in<br />
manufacturing science <strong>and</strong> Engineering<br />
SPOnSOred by bristol-Myers<br />
Squibb Company<br />
McCormick Place Convention Center<br />
room w196<br />
tuesday, October 16, <strong>2012</strong><br />
8:30 am – 12:00 pm<br />
Ekneet Kaur sahni<br />
univerSity Of COnneCtiCut<br />
Contact Drying in an Agitated Filter-Dryer:<br />
Experiments <strong>and</strong> Simulations<br />
8<br />
Awards Program<br />
<strong>aaps</strong> graduate student symposium<br />
in physical pharmacy <strong>and</strong><br />
Biopharmaceutics<br />
SPOnSOred by bristol-Myers<br />
Squibb Company<br />
McCormick Place Convention Center<br />
room w196<br />
tuesday, October 16, <strong>2012</strong><br />
8:30 am – 12:00 pm<br />
caleb Brian<br />
univerSity Of wiSCOnSin, MAdiSOn<br />
Surface Diffusion <strong>of</strong> the Organic<br />
Glass Nifedipine<br />
sunny Bhardwaj<br />
univerSity Of MinneSOtA<br />
Molecular Mobility as an Effective Predictor<br />
<strong>of</strong> the Physical Stability <strong>of</strong> Amorphous State<br />
<strong>aaps</strong> graduate student symposium in<br />
pharmacokinetics, pharmacodynamics,<br />
<strong>and</strong> drug metabolism <strong>and</strong> clinical<br />
pharmacology <strong>and</strong> Translational<br />
research<br />
SPOnSOred by eli lilly <strong>and</strong> Company<br />
McCormick Place Convention Center<br />
room w184<br />
tuesday, October 16, <strong>2012</strong><br />
8:30 am – 12:00 pm
ajendra s. Kadam<br />
univerSity Of COlOrAdO<br />
Expression <strong>and</strong> Activity <strong>of</strong> Drug Transporters<br />
in Human Ocular Barriers <strong>and</strong> Disease<br />
Related Changes: Implications for<br />
Transporter Guided Retinal Drug Delivery<br />
nimita dave<br />
univerSity Of CinCinnAti<br />
Brain/Brain Tumor Pharmacokinetics <strong>and</strong><br />
Pharmacodynamics <strong>of</strong> Letrozole<br />
rachel J. Eclov<br />
univerSity Of CAlifOrniA, SAn frAnCiSCO<br />
In Vivo Characterization <strong>of</strong> ABCG2 Enhancers<br />
Bridget morse<br />
univerSity At buffAlO, Suny<br />
Effect <strong>of</strong> Monocarboxylate Transporter<br />
Inhibition on the Oral Toxicokinetics/<br />
Toxicodynamics <strong>of</strong> γ-hydroxybutyrate (GHB)<br />
<strong>and</strong> γ-butyrolactone (GBL)<br />
award recipients<br />
ramola sane<br />
univerSity Of MinneSOtA<br />
Application <strong>of</strong> a Novel Microemulsion<br />
Formulation <strong>of</strong> Elacridar to Improve Drug<br />
Distribution into the Brain for Therapy <strong>of</strong><br />
Glioblastoma<br />
Hoi Kei lon<br />
univerSity At buffAlO, Suny<br />
Modeling Effects <strong>of</strong> Dexamethasone on<br />
Disease Progression <strong>of</strong> Bone Mineral Density<br />
in Collagen-induced Arthritic Rats<br />
<strong>aaps</strong> Outst<strong>and</strong>ing graduate student<br />
research award in pharmaceutical<br />
Technologies<br />
SPOnSOred by Covidien<br />
Qi (Tony) Zhou<br />
MOnASh univerSity, AuStrAliA<br />
Effect <strong>of</strong> Surface Coating with Magnesium<br />
Stearate via Mechanical Dry Powder<br />
Coating Approach on the Aerosol<br />
Performance <strong>of</strong> Micronized Drug Powders<br />
from Dry Powder Inhalers<br />
<strong>2012</strong> AAPS Annual Meeting <strong>and</strong> <strong>Exposition</strong> 9
award recipients<br />
mentor: david a V morton, ph.d.<br />
MOnASh univerSity, AuStrAliA<br />
<strong>aaps</strong> lipid-based drug delivery<br />
graduate student award<br />
SPOnSOred by gattefossé Corporation<br />
McCormick Place Convention Center<br />
room w186<br />
Monday, October 15, <strong>2012</strong><br />
12:15 pm – 1:15 pm<br />
Yan Yan Yeap<br />
MOnASh univerSity, AuStrAliA<br />
<strong>aaps</strong> graduate student award<br />
in Quality by design <strong>and</strong> product<br />
performance<br />
SPOnSOred by Quality by design <strong>and</strong><br />
Product Performance focus group<br />
McCormick Place Convention Center<br />
room w178<br />
Monday, October 15, <strong>2012</strong><br />
4:30 pm – 5:30 pm<br />
rishi Kapil<br />
PAnJAb univerSity (uiPS), indiA<br />
10<br />
Awards Program<br />
<strong>aaps</strong> Ocular drug delivery &<br />
disposition focus group graduate<br />
student poster award<br />
SPOnSOred by bausch <strong>and</strong> lomb<br />
McCormick Place Convention Center<br />
room w185<br />
Monday, October 15, <strong>2012</strong><br />
12:15 pm – 1:15 pm<br />
megha Barot<br />
univerSity Of MiSSOuri, KAnSAS City<br />
<strong>aaps</strong> postdoctoral fellow award<br />
SPOnSOred by Abbott laboratories<br />
<strong>and</strong> Merck<br />
The AAPS Postdoctoral Fellow Award<br />
is given <strong>annual</strong>ly to individuals who<br />
demonstrated excellence in his/her research<br />
work during a postdoctoral training period<br />
<strong>and</strong> shows exceptional promise in future<br />
contributions to pharmaceutical sciences.<br />
courtney sloan, ph.d.<br />
univerSity Of illinOiS At urbAnA-ChAMPAign<br />
Dr. Sloan received her Ph.D. in<br />
Pharmaceutical Chemistry from the<br />
University <strong>of</strong> Kansas under the guidance <strong>of</strong><br />
Dr. Susan Lunte in 2011. While in graduate<br />
school, Dr. Sloan developed analytical<br />
methods for characterizing the metabolism<br />
<strong>of</strong> neuropeptides involved in pain signaling,<br />
neurotoxicity, <strong>and</strong> addiction. Additionally,<br />
she investigated the transport <strong>of</strong> peptide<br />
metabolites at the blood-brain barrier.<br />
utilizing bovine brain microvessel endothelial<br />
cells. Currently at the University <strong>of</strong> Illinois at
Urbana-Champaign (UIUC) she is working<br />
in Dr. Ryan Bailey’s group in a collaborative<br />
effort with Dr. Stephen Sligar’s group,<br />
also at UIUC. Pr<strong>of</strong>essor Bailey’s group has<br />
extensively developed silicon photonics as<br />
an analytical tool to investigate molecular<br />
binding events <strong>and</strong> kinetics with soluble<br />
biomolecules such as DNA <strong>and</strong> antibodies.<br />
Dr. Sloan is demonstrating the utility <strong>of</strong> the<br />
optical microring resonator platform for<br />
studying interactions between membranebound<br />
proteins <strong>and</strong> soluble lig<strong>and</strong>s,<br />
utilizing nanodiscs to solubilize membrane<br />
proteins <strong>and</strong> maintain their structure in a<br />
native-like lipid bilayer. Microrings provide<br />
a highly multiplexed analysis platform<br />
for characterizing these receptor-lig<strong>and</strong><br />
interactions. Dr. Sloan hopes to develop<br />
the platform to investigate the role <strong>of</strong> G<br />
protein coupled receptors (GPCRs) as<br />
pharmaceutical targets <strong>and</strong> monitor G<br />
protein coupling as indicators for potential<br />
<strong>of</strong>f-target drug effects.<br />
sumith a. Kulartne, ph.d.<br />
the SCriPPS reSeArCh inStitute<br />
Dr. Kulartne is the Vice President <strong>of</strong><br />
Research & Development, On Target<br />
Laboratories, LLC, West Lafayette, IN (March<br />
<strong>2012</strong>– present). Under his guidance, On<br />
Target is developing targeted-Near Infra<br />
Red (NIR) imaging agents that detect<br />
tumor margins during surgery for cancers<br />
<strong>and</strong> biologics for inflammatory diseases.<br />
On Target is conducting multiple clinical<br />
trials at Mayo clinics, UPenn, IU Medical<br />
School for cancers such as ovarian, lung,<br />
prostate, <strong>and</strong> kidney. Dr. Kularatne pursued<br />
his postdoctoral studies in biomedicines<br />
to target metastatic cancers, cancer stem<br />
cells, acute myeloid leukemia, <strong>and</strong> ovarian<br />
cancer using anti-CXCR4, IL3, <strong>and</strong> bispecific<br />
antibodies with Dr. Peter G. Schultz, The<br />
Scripps Research Institute, La Jolla, CA<br />
(Dec 2009–Feb <strong>2012</strong>). He earned his<br />
award recipients<br />
Ph.D. in organic/medicinal chemistry from<br />
Purdue University (Dec 2005-Dec 2009),<br />
conducting research under the guidance<br />
<strong>of</strong> Ralph C. Corley Distinguished Pr<strong>of</strong>essor<br />
Philip S. Low. During his doctoral studies,<br />
Dr. Kularatne has developed PSMA-targeted<br />
SPECT, PET, <strong>and</strong> optical imaging <strong>and</strong><br />
therapeutic agents for prostate cancer.<br />
He has also developed folate receptortargeted<br />
PET imaging <strong>and</strong> therapeutic.<br />
PSMA-targeted SPECT imaging agent that<br />
he developed is currently evaluating in<br />
Phase I clinical trials at IU Medical School<br />
<strong>and</strong> PSMA-targeted therapeutic agents are<br />
under clinical development at Endocyte Inc,<br />
West Lafayette, IN.<br />
Innovation in nanotechnology award<br />
SPOnSOred by hospira<br />
McCormick Place Convention Center<br />
room w190b<br />
tuesday, October 16, <strong>2012</strong><br />
4:30 pm – 5:30 pm<br />
This award is intended to recognize <strong>and</strong><br />
promote the achievement <strong>of</strong> an individual<br />
that demonstrates innovation in the area<br />
<strong>of</strong> nanotechnology as applied to drug <strong>and</strong><br />
device development.<br />
arun Kumar upadhyay, ph.d.<br />
univerSity Of COlOrAdO AnSChutz<br />
MediCAl CAMPuS<br />
Dr. Upadhyay has developed protein,<br />
polymer, <strong>and</strong> virus based nanosystems<br />
for enhanced <strong>and</strong>/or sustained delivery <strong>of</strong><br />
therapeutic agents including small molecule<br />
drugs, peptides, <strong>and</strong> proteins. He also<br />
elucidated the mechanisms <strong>of</strong> inclusion<br />
body formation <strong>and</strong> developed approaches<br />
for efficient purification <strong>of</strong> protein drugs.<br />
His long term goals include development <strong>of</strong><br />
new drugs <strong>and</strong> delivery systems for treating<br />
retinal degenerative diseases.<br />
<strong>2012</strong> AAPS Annual Meeting <strong>and</strong> <strong>Exposition</strong> 11
award recipients<br />
Outst<strong>and</strong>ing Educator award<br />
SPOnSOred by biogen idec<br />
The AAPS Outst<strong>and</strong>ing Educator Award<br />
recognizes excellence in education in the<br />
technologies related to pharmaceuticals.<br />
John l. neumeyer, ph.d.<br />
hArvArd MediCAl SChOOl/MCleAn hOSPitAl/<br />
AdArC<br />
Dr. Neumeyer, Matthews Distinguished<br />
Pr<strong>of</strong>essor <strong>of</strong> Medicinal Chemistry (Emeritus)<br />
at Northeastern University, has been<br />
designing <strong>and</strong> synthesizing molecules for<br />
mapping <strong>and</strong> studying dopamine receptors<br />
in the brain. Parkinson’s disease (PD) is<br />
caused by the degeneration <strong>of</strong> a set <strong>of</strong><br />
neurons in the brain that use dopamine as a<br />
neurotransmitter. By modifying the structure<br />
<strong>of</strong> apomorphine, a dopamine receptor<br />
agonist, <strong>and</strong> related aporphines, chemists,<br />
pharmacologists <strong>and</strong> molecular biologists<br />
could infer the 3D arrangement <strong>of</strong> amino<br />
acids at the dopamine-binding site. On the<br />
other h<strong>and</strong>, chemical analogs related to<br />
cocaine as well as cocaine itself, are known<br />
to inhibit dopamine uptake by binding to<br />
cocaine receptor sites. Thus, suitably labeled<br />
cocaine analogs could be used as probes to<br />
investigate the neurochemical mechanism<br />
<strong>of</strong> Parkinson’s disease <strong>and</strong> other disorders<br />
involving dopamine neurotransmitters.<br />
This type <strong>of</strong> thinking led Neumeyer <strong>and</strong> his<br />
co-workers to synthesize a new radiotracer<br />
[¬123I]-¬¬CIT. This tracer can be used<br />
in single-photon emission computed<br />
tomography (SPECT) imaging to pinpoint<br />
sites where dopamine is taken up. Similarly,<br />
the imaging technique known as positron<br />
emission tomography (PET) requires<br />
positron-emitting nuclides such as 18F or 11C.<br />
The radiotracer [¬123I]-FP¬CIT (i<strong>of</strong>lupane,<br />
DATscan ® ) is now a commercially available<br />
imaging agent used for the early diagnosis<br />
<strong>of</strong> PD or to monitor the progression <strong>of</strong> PD<br />
in patients.<br />
12<br />
Awards Program<br />
Dr. Neumeyer has trained over 60 graduate<br />
students <strong>and</strong> post-doctoral fellows in the<br />
pharmaceutical sciences at Northeastern<br />
University <strong>and</strong> continues to train postdoctoral<br />
fellows as Director <strong>of</strong> the Medicinal<br />
Chemistry Program at McLean Hospital,<br />
Harvard Medical School.<br />
new Investigator grant in<br />
pharmaceutics <strong>and</strong> the<br />
pharmaceutical Technologies<br />
SPOnSOred by Pfizer global research<br />
<strong>and</strong> development<br />
The AAPS New Investigator Grant in<br />
Pharmaceutics <strong>and</strong> the Pharmaceutical<br />
Technologies is a one-time grant <strong>of</strong> $25,000<br />
to be used to support the research efforts<br />
<strong>of</strong> an individual actively engaged in training<br />
graduate students <strong>and</strong> carrying out the basic<br />
research in pharmaceutics, drug delivery<br />
<strong>and</strong>/or the pharmaceutical technologies.<br />
seungpyo Hong, ph.d.<br />
univerSity Of illinOiS At ChiCAgO<br />
Dr. Hong is Assistant Pr<strong>of</strong>essor in the<br />
Department <strong>of</strong> Biopharmaceutical Sciences<br />
at the University <strong>of</strong> Illinois at Chicago. He<br />
received his B.S. <strong>and</strong> M.S. degrees from<br />
Polymer Engineering at Hanyang University,<br />
Seoul, Korea in 1999 <strong>and</strong> 2011, respectively.<br />
In 2006, he graduated with his Ph.D. in<br />
Macromolecular Science <strong>and</strong> Engineering at<br />
the University <strong>of</strong> Michigan (advisors: Pr<strong>of</strong>s.<br />
Mark Banaszak Holl <strong>and</strong> James Baker, Jr.)<br />
before he joined Pr<strong>of</strong>. Robert Langer’s lab<br />
at MIT for his postdoctoral training. Since<br />
2008, he has established an independent<br />
research program under the overall theme<br />
<strong>of</strong> “Biomimetic Nanotechnology”, focusing<br />
on three major areas: 1) Nanocarrier systems<br />
for targeted delivery <strong>of</strong> therapeutics<br />
using biomimetic approaches; 2) Topical,<br />
transdermal delivery systems for breast<br />
cancer prevention using nanoparticle-drug
combinations; <strong>and</strong> 3) Biomimetic micr<strong>of</strong>luidic<br />
chips for effective separation <strong>of</strong> circulating<br />
tumor cells. He has published over 35 peerreviewed<br />
articles that have been cited a<br />
combined total <strong>of</strong> over 2,200 times, three<br />
book chapters, <strong>and</strong> nine patents (pending or<br />
awarded) while presenting 33 invited talks<br />
<strong>and</strong> over 80 conference proceedings.<br />
<strong>aaps</strong> community service award<br />
SPOnSOred by the university <strong>of</strong> Colorado/<br />
Center for Pharmaceutical biotechnology<br />
The AAPS Community Service Award is<br />
intended to recognize an AAPS member<br />
for the personal effort that he/she created<br />
<strong>and</strong> managed, preferably as a volunteer <strong>and</strong><br />
not part <strong>of</strong> duties in a paid position, for a<br />
sustained community service effort.<br />
Joseph w. polli, ph.d.<br />
glAxOSMithKline, inC.<br />
Dr. Joseph Polli received the AAPS<br />
Community Service Award for service to Cub<br />
Scout Pack 152, Boy Scout Troop 152 <strong>and</strong><br />
the Crosswinds District <strong>of</strong> the Boys Scouts<br />
<strong>of</strong> America located in Cary, North Carolina.<br />
Over the past 14 years, he has contributed<br />
to the skills <strong>and</strong> leadership development<br />
<strong>of</strong> more than one hundred young men,<br />
provided organizational leadership to the<br />
BSA, developed the high adventure outdoor<br />
camping program, <strong>and</strong> has donated financial<br />
support. One highlight <strong>of</strong> Dr. Polli’s service<br />
includes founding <strong>and</strong> chartering Troop 152<br />
with 6 scouts in 2003. Twenty-five scouts<br />
have since obtained the rank <strong>of</strong> Eagle. Dr.<br />
Polli has held multiple leadership positions,<br />
including being the founding Committee<br />
Chair <strong>of</strong> Troop 152, Charter Organizational<br />
Representative, Assistant Scoutmaster,<br />
Secretary/Treasurer <strong>and</strong> District Eagle<br />
Board <strong>of</strong> Review Member. In addition, Joe<br />
is an avid camper who challenges scouts<br />
to go beyond what they believe they are<br />
capable <strong>of</strong> achieving. Outside <strong>of</strong> scouting,<br />
award recipients<br />
Dr. Polli is an internationally recognized<br />
researcher in membrane transporters <strong>and</strong><br />
drug development. His main research<br />
interests include membrane transporters that<br />
influence drug disposition, prediction <strong>of</strong> drug<br />
interactions, <strong>and</strong> processes to enhance the<br />
development <strong>of</strong> drug c<strong>and</strong>idates.<br />
The IpEc foundation ralph shangraw<br />
memorial award<br />
The Ralph Shangraw Memorial Award is<br />
to be awarded to any person who has<br />
provided outst<strong>and</strong>ing research contributions<br />
in the study <strong>of</strong> excipients or excipientrelated<br />
technology over a number <strong>of</strong> years,<br />
including an underst<strong>and</strong>ing <strong>of</strong> the basic<br />
science underlying excipient functionality<br />
<strong>and</strong> the development <strong>of</strong> new excipients or<br />
noveluse <strong>of</strong> existing excipients.<br />
Hans E. Junginger, ph.d. (retired)<br />
MArbury, gerMAny<br />
Pr<strong>of</strong>essor Junginger received his Ph.D. at<br />
the University <strong>of</strong> Saarl<strong>and</strong> (Germany) in 1971.<br />
He was a Pr<strong>of</strong>essor <strong>of</strong> pharmaceutics <strong>and</strong><br />
the Head <strong>of</strong> the Division <strong>of</strong> Pharmaceutical<br />
Technology at the Leiden/Amsterdam Center<br />
for Drug Research, Leiden University, The<br />
Netherl<strong>and</strong>s, until February 1, 2004 when he<br />
went with early retirement. His main research<br />
areas include the development <strong>of</strong> novelcontrolled<br />
drug delivery systems peroral<br />
routes, utilizing new (bioadhesive) polymers<br />
for the nasal, pulmonary <strong>and</strong> oral route for<br />
peptides, proteins, <strong>and</strong> (DNA) vaccines.<br />
He also was strongly involved in (trans)<br />
dermal drug research <strong>and</strong> has developed<br />
more than 100 cosmetics products based<br />
on aloe vera. He has received several major<br />
awards including the <strong>American</strong> <strong>Association</strong> <strong>of</strong><br />
Pharmaceutical Scientists (AAPS) Dr. Rainer<br />
H<strong>of</strong>fman Product through Science Award, <strong>and</strong><br />
three honorary doctorates (Gent, Belgium, in<br />
1995, Potchefstroom University in South Africa<br />
in 2003, <strong>and</strong> London University, UK in 2004).<br />
<strong>2012</strong> AAPS Annual Meeting <strong>and</strong> <strong>Exposition</strong> 13
award rEcIpIEnTs<br />
The IpEc foundation Industry<br />
research achievement in Excipient<br />
Technology award<br />
The Industry Research Achievement in<br />
Excipient Technology Award is to recognize<br />
individuals working in an industrial setting<br />
who have made significant contributions in<br />
the filed <strong>of</strong> excipient technology.<br />
Brian a c carlin, ph.d.<br />
fMC biOPOlyMer<br />
Pr<strong>of</strong>essor Brian Carlin is Director <strong>of</strong> Open<br />
Innovation (Pharma), at FMC BioPolymer.<br />
He was previously the Global Mgr<br />
Pharmaceutical R&D <strong>and</strong> has been with FMC<br />
for seventeen years. Pr<strong>of</strong>essor Carlin chairs<br />
the IPEC Americas Quality by Design <strong>and</strong><br />
Excipient Composition Committees <strong>and</strong> also<br />
serves on the USP Excipient Committee.<br />
Prior to joining FMC Pr<strong>of</strong>essor Carlin<br />
worked at SmithKline & French/SmithKline<br />
Beecham in new product development<br />
for eleven years. He started in the industry<br />
with Richardson Vicks, working for five<br />
years in commercial product development.<br />
He obtained his doctorate in Interfacial<br />
Rheology from the School <strong>of</strong> Pharmacy,<br />
University <strong>of</strong> London, <strong>and</strong> an Honours<br />
degree in Pharmacy from the University<br />
<strong>of</strong> Aston in Birmingham. He serves on the<br />
distance learning MSc course at Demontfort<br />
University, UK, where he is an honorary<br />
visiting Pr<strong>of</strong>essor. Pr<strong>of</strong>essor Carlin has been<br />
a leading advocate for innovative scientific<br />
approaches to excipients <strong>and</strong> pharmaceutics<br />
in pursuit <strong>of</strong> the QbD vision <strong>of</strong> the 21st<br />
century cGMP initiative.<br />
14<br />
Awards Program<br />
Outst<strong>and</strong>ing manuscript award in<br />
analysis <strong>and</strong> pharmaceutical Quality<br />
SPOnSOred by Celgene<br />
The AAPS Outst<strong>and</strong>ing Manuscript Award<br />
in Analysis <strong>and</strong> Pharmaceutical Quality<br />
is intended to recognize outst<strong>and</strong>ing<br />
achievement in Pharmaceutical Analysis<br />
<strong>and</strong> Quality as demonstrated by author(s)<br />
in a manuscript published in an analytically<br />
focused journal.<br />
raj suryanarayanan, ph.d.<br />
univerSity Of MinneSOtA<br />
Kapildev K. arora, ph.d.<br />
univerSity Of MinneSOtA<br />
nitin g. Tayade, ph.d.<br />
univerSity Of MinneSOtA
Outst<strong>and</strong>ing manuscript award in<br />
modeling <strong>and</strong> simulation<br />
SPOnSOred by Projections research<br />
The AAPS Outst<strong>and</strong>ing Manuscript in<br />
Modeling <strong>and</strong> Simulation Award is intended<br />
to recognize outst<strong>and</strong>ing achievement<br />
in modeling <strong>and</strong> simulation in clinical<br />
pharmacology <strong>and</strong> translational research as<br />
demonstrated by the author in the quality<br />
<strong>and</strong> originality <strong>of</strong> a manuscript published in<br />
any peer-reviewed journal.<br />
paulo paixão, ph.d.<br />
univerSity Of liSbOn, POrtugAl<br />
José a.g. morais, ph.d.<br />
univerSity Of liSbOn, POrtugAl<br />
luís f. gouveia, ph.d.<br />
univerSity Of liSbOn, POrtugAl<br />
award rEcIpIEnTs<br />
Pharmaceutical Research meritorious<br />
manuscript award<br />
SPOnSOred by Pfizer inc.<br />
The AAPS Pharmaceutical Research<br />
Meritorious Manuscript Award recognizes<br />
outst<strong>and</strong>ing achievement in the<br />
pharmaceutical sciences as demonstrated<br />
by the author in the quality <strong>and</strong> originality <strong>of</strong><br />
a manuscript published in the <strong>of</strong>ficial AAPS<br />
journal, Pharmaceutical Research.<br />
Underst<strong>and</strong>ing the Behavior <strong>of</strong> Amorphous<br />
Pharmaceutical Systems during Dissolution<br />
Pharmaceutical Research, 27, Number 4<br />
(2010), DOI: 10.1007/s11095-009-0021-1<br />
lynne s. Taylor, ph.d. david E. alonzo, ph.d.<br />
Purdue univerSity AbbOtt lAbOrAtOrieS<br />
deliang Zhou, ph.d. Yi gao, ph.d.<br />
AbbOtt lAbOrAtOrieS AbbOtt lAbOrAtOrieS<br />
ge<strong>of</strong>f g.Z. Zhang, ph.d.<br />
AbbOtt lAbOrAtOrieS<br />
<strong>2012</strong> AAPS Annual Meeting <strong>and</strong> <strong>Exposition</strong> 15
<strong>aaps</strong> fEllOws<br />
<strong>aaps</strong> fellows<br />
AAPS confers the honor <strong>of</strong> Fellow to recognize individuals for outst<strong>and</strong>ing contributions,<br />
which elevate the stature <strong>of</strong> the pharmaceutical sciences, <strong>and</strong> for pr<strong>of</strong>essional excellence<br />
in the field relevant to the mission <strong>of</strong> AAPS. The primary criterion for selection as an AAPS<br />
Fellow is pr<strong>of</strong>essional competence reflected through scholarly <strong>and</strong> research contributions<br />
to the pharmaceutical sciences such as original articles, scientific presentations at <strong>annual</strong><br />
<strong>meeting</strong>s, <strong>and</strong>/or patents.<br />
Okezie I. aruoma, m.B.a., d. sc., ph.d.<br />
AMeriCAn univerSity Of heAlth SCienCeS<br />
Dr. Aruoma has developed an internationally<br />
recognized program in translational<br />
sciences research with direction focused<br />
on the underst<strong>and</strong>ing the bioefficacy <strong>of</strong><br />
functional nutraceuticals derived from fruits,<br />
vegetables <strong>and</strong> medicinal plants <strong>and</strong> how<br />
these may potentially prevent or reverse<br />
the promotion or progression <strong>of</strong> the chronic<br />
diseases with overt inflammation (such<br />
as diabetes, cancers, rheumatoid arthritis,<br />
Parkinson’s <strong>and</strong> Alzheimer’s). The associated<br />
cognitive functions impairment, movement,<br />
psychopathological <strong>and</strong> behavioral disorders<br />
significantly decreases the quality <strong>of</strong> life. Dr<br />
Aruoma’s research team assessed the effect<br />
<strong>of</strong> black tea on risk factors <strong>of</strong> cardiovascular<br />
disease in patients with diabetes <strong>and</strong><br />
in normal population at risk <strong>of</strong> diabetes<br />
<strong>and</strong> found that black tea consumption<br />
reduces uric acid <strong>and</strong> C-reactive protein<br />
levels <strong>and</strong> decreased the LDL/HDL ratio,<br />
an outcome that may benefit humans<br />
at high risk <strong>of</strong> cardiovascular events <strong>and</strong><br />
may augment prescription drug therapy.<br />
The long term objectives <strong>of</strong> Dr Aruoma’s<br />
research is enshrined in the context <strong>of</strong><br />
the search for functional nutraceuticals<br />
as neuroprotectants, cardioprotectants<br />
<strong>and</strong> cognitive enhancers with proven<br />
bioefficacy that not only meet the public<br />
health concerns but can be responsive to a<br />
comprehensive portfolio <strong>of</strong> biomarkers that<br />
can benefit testing for the complications <strong>of</strong><br />
diabetes <strong>and</strong> neurodegenerative diseases.<br />
16<br />
Awards Program<br />
alekha K. dash, r.ph., ph.d.<br />
CreightOn univerSity<br />
Dr. Alekha K. Dash received his bachelor’s<br />
<strong>and</strong> master’s degrees in Pharmacy from<br />
Jadavpur University, India, <strong>and</strong> a Ph.D.<br />
from the University <strong>of</strong> Minnesota. He is<br />
pr<strong>of</strong>essor <strong>and</strong> chair <strong>of</strong> the Department <strong>of</strong><br />
Pharmacy Sciences, Creighton University,<br />
<strong>and</strong> holds the Gilbert F. Taffe Jr. Endowed<br />
Chair <strong>of</strong> Pharmacy. Dr. Dash’s research<br />
interests include design <strong>and</strong> evaluation <strong>of</strong><br />
novel drug delivery systems, preformulation<br />
studies, solid-state pharmaceutics, <strong>and</strong><br />
pharmaceutical analysis. Dr. Dash has made<br />
unique <strong>and</strong> outst<strong>and</strong>ing contributions to<br />
numerous facets <strong>of</strong> pharmaceutical analysis.<br />
In light <strong>of</strong> his interest in drug delivery,<br />
the analytical methods developed were<br />
applied to the fabrication <strong>and</strong> evaluation <strong>of</strong><br />
novel drug delivery systems. In situ gel for<br />
sustained drug delivery <strong>and</strong> targeting, solidlipid<br />
nanoparticles for tumor localization, <strong>and</strong><br />
nanoparticulate delivery for HIV treatment<br />
are few examples. He has received several<br />
awards for teaching, research, <strong>and</strong> service.<br />
Dr. Dash has more than 50 peer reviewed<br />
publications, 120 poster <strong>and</strong> podium<br />
presentations, <strong>and</strong> several approved patents.<br />
He is a member <strong>of</strong> six pr<strong>of</strong>essional societies,<br />
serves on numerous editorial boards, <strong>and</strong><br />
is a reviewer for 20 peer-reviewed journals.<br />
He has authored chapters in a number <strong>of</strong><br />
texts, <strong>and</strong> has been an invited speaker at the<br />
international, national, <strong>and</strong> local levels.
melgardt m. de Villiers, B. pharm., ph.d.<br />
univerSity Of wiSCOnSin – MAdiSOn<br />
Dr. de Villiers <strong>of</strong> the University <strong>of</strong> Wisconsin,<br />
has developed an internationally recognized<br />
research program in the application<br />
<strong>of</strong> thin coatings to improve the solidstate<br />
properties <strong>of</strong> drugs <strong>and</strong> excipients.<br />
This program has revolved around the<br />
application <strong>of</strong> layer-by-layer self-assembled<br />
nanocoatings on pharmaceutically<br />
important surfaces. His group was the first<br />
to apply this technology to create slow<br />
release nanoparticles (furosemide <strong>and</strong><br />
dexamethasone), protective nanoshells<br />
(photo-protection <strong>of</strong> light sensitive drugs)<br />
around drug particles <strong>and</strong> to produce<br />
improved excipients (directly compressible<br />
lignocellulose). Dr. de Villiers is also an<br />
adjunct-pr<strong>of</strong>essor in the School <strong>of</strong> Pharmacy<br />
at North-West University, South Africa.<br />
With his colleagues from South Africa their<br />
work on the quality <strong>of</strong> drug <strong>and</strong> excipient<br />
raw materials has made several important<br />
contributions. For example, this work has<br />
led to several publications highlighting the<br />
importance <strong>of</strong> recognizing that polymorph<br />
identification plays a role in the quality <strong>of</strong><br />
generic drugs. His work on the effect <strong>of</strong><br />
mebendazole has led to a change in The<br />
International Pharmacopoeia (4th Edition<br />
<strong>of</strong> the International Pharmacopoeia, WHO).<br />
This monograph now clearly states “…<br />
Mebendazole exhibits polymorphism. The<br />
polymorph specified in the monograph<br />
(form C) corresponds to the crystal form <strong>of</strong><br />
mebendazole RS.”<br />
<strong>aaps</strong> fEllOws<br />
glen s. Kwon, ph.d.<br />
univerSity Of wiSCOnSin – MAdiSOn<br />
Dr. Kwon is a pr<strong>of</strong>essor <strong>and</strong> holder <strong>of</strong> the<br />
inaugural Jens T. Carstensen Distinguished<br />
Chair in the School <strong>of</strong> Pharmacy at the<br />
University <strong>of</strong> Wisconsin. His research<br />
program focuses on polymeric assemblies<br />
for drug delivery, non-viral gene delivery<br />
<strong>and</strong> optical imaging. In this context, his<br />
interests in pharmaceutical research include<br />
drug solubilization, controlled release<br />
<strong>and</strong> tumor targeting. His research team<br />
has extensively studied amphiphilic block<br />
copolymer (ABC) micelles as nanoscopic<br />
supramolecular core/shell structures for<br />
drug delivery. The design <strong>and</strong> chemistry<br />
<strong>of</strong> ABC micelles has addressed drug<br />
loading for drug solubilization, safety for<br />
intravenous injection, pharmacokinetics <strong>and</strong><br />
extracellular or intracellular drug release. He<br />
has pioneered multiple drug solubilization<br />
by ABC micelles using physical interactions<br />
<strong>and</strong> chemical pro-drug strategies. In the<br />
former case, simple changes in side chains<br />
<strong>of</strong> a core-forming block have been used to<br />
tune drug loading <strong>and</strong> release. In the latter<br />
case, drug release depends on pH, providing<br />
a strategy for triggered multi-drug release<br />
in endosomes/lysosomes <strong>of</strong> cancer cells. Dr.<br />
Kwon participates in collaborative research<br />
on multi-modal therapeutic strategies that<br />
involve hybrid nanomedicines that are<br />
bio-responsive, synergistic <strong>and</strong> theranostic,<br />
aiming for progress against lung, breast <strong>and</strong><br />
ovarian cancers <strong>and</strong> life-threatening systemic<br />
fungal diseases.<br />
<strong>2012</strong> AAPS Annual Meeting <strong>and</strong> <strong>Exposition</strong> 17
<strong>aaps</strong> fEllOws<br />
Tarun K. m<strong>and</strong>al, m. pharm., ph.d.<br />
xAvier univerSity Of lOuiSiAnA<br />
Dr. M<strong>and</strong>al is an Endowed Pr<strong>of</strong>essor <strong>of</strong><br />
Pharmacy at Xavier University <strong>of</strong> Louisiana.<br />
He has been recognized for his outst<strong>and</strong>ing<br />
contributions in the area <strong>of</strong> novel <strong>and</strong><br />
innovative drug delivery. His research<br />
focuses on the design <strong>and</strong> development <strong>of</strong><br />
commercially viable formulations to improve<br />
the safety, efficacy, <strong>and</strong> patient compliance.<br />
Cutting-edge research in his laboratory has<br />
resulted in controlled release formulations<br />
<strong>of</strong> many therapeutic agents. The<br />
microencapsulation techniques developed<br />
in his lab have resulted in effective control<br />
release formulations for large <strong>and</strong> small<br />
molecules with varying water solubility. His<br />
group has developed a film coating process<br />
that permits a less complex application <strong>of</strong><br />
multiple coats on a substrate to control the<br />
release <strong>of</strong> active ingredients. Working in<br />
the area <strong>of</strong> Nanotechnology, his group has<br />
developed orally active nanoparticles to<br />
treat radiation injury. The use <strong>of</strong> siRNA for<br />
the treatment <strong>of</strong> life threatening diseases<br />
like cancer <strong>and</strong> infectious diseases is another<br />
area <strong>of</strong> interest <strong>of</strong> his group. His group has<br />
developed a novel lipid based non-toxic<br />
siRNA-nanoparticle for the treatment <strong>of</strong><br />
Hepatitis C. He has published close to 200<br />
original research paper, review, abstracts,<br />
<strong>and</strong> monographs <strong>and</strong> filed four patents.<br />
18<br />
Awards Program<br />
mehul u. mehta, ph.d.<br />
u.S. fOOd And drug AdMiniStrAtiOn<br />
Dr. Mehta has been the Director <strong>of</strong> Division<br />
<strong>of</strong> Clinical Pharmacology (CP) I in CDER,<br />
FDA for the last 14 years. During this<br />
period, he has worked tirelessly to bring<br />
out regulatory guidances in the areas <strong>of</strong><br />
Biopharmaceutics <strong>and</strong> CP with the intent to<br />
avoid unnecessary human bioequivalence<br />
studies, based on robust science, <strong>and</strong> to<br />
guide drug development by defining best<br />
practices in CP. Thus, under his leadership,<br />
the Agency issued two guidances with<br />
significant <strong>and</strong> positive impact. The first<br />
one, “SUPAC – MR” guidance provided<br />
regulatory relief to the manufacturers <strong>of</strong><br />
modified release products when faced<br />
with scale-up <strong>and</strong> post-approval changes,<br />
based on judicious in-vitro <strong>and</strong> in-vivo<br />
tests. The second guidance, “PK in Hepatic<br />
Impairment”, st<strong>and</strong>ardized the conduct <strong>and</strong><br />
assessment <strong>of</strong> pharmacokinetic studies in<br />
hepatic impairment for all new drugs <strong>and</strong><br />
has played a pivotal part in proper dosing<br />
recommendations in this important patient<br />
population for hundreds <strong>of</strong> new drugs. Dr.<br />
Mehta is also a leading Agency scientist on<br />
the Biopharmaceutics Classification System<br />
(BCS) <strong>and</strong> has been the co-chair <strong>of</strong> the<br />
CDER BCS Committee for last 8 years where<br />
he has helped the Agency implement the<br />
BCS guidance <strong>and</strong> granting <strong>of</strong> BCS based<br />
biowaivers for nearly 100 drug products.
michael a. repka, d.d.s., ph.d.<br />
univerSity Of MiSSiSSiPPi<br />
Dr. Michael A. Repka’s most important<br />
scientific accomplishments involve the<br />
advancement <strong>of</strong> hot melt extrusion (HME)<br />
technology. He has established himself<br />
as an expert in this major pharmaceutical<br />
processing field, through his numerous<br />
peer-reviewed publications, presentations<br />
<strong>and</strong> scientific talks. Polymeric drug delivery<br />
design <strong>and</strong> stabilization, formulation <strong>and</strong><br />
process development for natural products,<br />
antifungal/antibacterial agents <strong>and</strong><br />
vaccines, are important components <strong>of</strong> his<br />
research. He has contributed significantly<br />
to several drug delivery areas including<br />
oral, transdermal/trans-nail, nose-to-brain,<br />
<strong>and</strong> transcorneal delivery. Dr. Repka is<br />
Chair <strong>and</strong> Pr<strong>of</strong>essor <strong>of</strong> the Department<br />
<strong>of</strong> Pharmaceutics <strong>and</strong> Director <strong>of</strong> the Pii<br />
Center for Pharmaceutical Technology at<br />
The University <strong>of</strong> Mississippi. He joined<br />
The University <strong>of</strong> Mississippi faculty after<br />
receiving his Ph.D. from The University<br />
<strong>of</strong> Texas, College <strong>of</strong> Pharmacy, <strong>and</strong> also<br />
founded a pharmaceutical research/<br />
development company specializing in drug<br />
delivery. Dr. Repka serves on the Editorial<br />
Advisory Boards <strong>of</strong> six prestigious journals,<br />
is Associate Editor for AAPS PharmSciTech<br />
<strong>and</strong> Editor for North America for Journal<br />
<strong>of</strong> Drug Delivery Science <strong>and</strong> Technology.<br />
He served as Chair <strong>of</strong> the Modified Release<br />
Focus Group (2011) <strong>and</strong> was subsequently<br />
elected Vice Chair <strong>of</strong> the Formulation Design<br />
<strong>and</strong> Development Section within AAPS.<br />
Dr. Repka regularly speaks at international<br />
HME symposia <strong>and</strong> workshops.<br />
<strong>aaps</strong> fEllOws<br />
lynne s. Taylor, ph.d.<br />
Purdue univerSity<br />
Dr. Taylor is well known for her research<br />
program in the area <strong>of</strong> the solid-state phase<br />
behavior <strong>of</strong> pharmaceutical materials. In<br />
particular, she has addressed the phase<br />
behavior <strong>of</strong> high energy solids such as<br />
amorphous forms, which are <strong>of</strong> interest<br />
for the delivery <strong>of</strong> poorly water soluble<br />
compounds. Much <strong>of</strong> her research in the<br />
area has revolved around the exploration <strong>of</strong><br />
polymers to inhibit crystallization <strong>of</strong> the drug<br />
from the formulation <strong>and</strong> the supersaturated<br />
solution generated upon dissolution <strong>of</strong><br />
the enabling formulation. Other important<br />
areas <strong>of</strong> research include addressing the<br />
role <strong>of</strong> water-solid interactions in promoting<br />
chemical <strong>and</strong> physical instabilities, as well<br />
as the investigation <strong>and</strong> application <strong>of</strong><br />
advanced analytical techniques for solidstate<br />
characterization. The long term<br />
goal <strong>of</strong> Dr. Taylor’s research is to gain<br />
a comprehensive underst<strong>and</strong>ing <strong>of</strong> the<br />
interplay between solid-state properties<br />
<strong>and</strong> drug performance in vivo.<br />
<strong>2012</strong> AAPS Annual Meeting <strong>and</strong> <strong>Exposition</strong> 19
<strong>aaps</strong> fEllOws<br />
Timothy s. Tracy, ph.d.<br />
univerSity Of KentuCKy<br />
Dr. Tracy has developed an internationally<br />
recognized program in the area <strong>of</strong><br />
human drug metabolism <strong>and</strong> disposition,<br />
centering on the role <strong>of</strong> cytochrome P450<br />
drug metabolizing enzymes, specifically<br />
CYP2C9. This has involved examination<br />
<strong>of</strong> the structure-function relationship <strong>of</strong><br />
CYP2C9 resulting in some <strong>of</strong> the seminal<br />
work on the conformational plasticity <strong>of</strong><br />
the P450 enzymes leading to a better<br />
underst<strong>and</strong>ing <strong>of</strong> not only their broad<br />
substrate specificity but also atypical<br />
enzyme kinetics. The work has exp<strong>and</strong>ed<br />
to examine the role in pharmacogenetics <strong>of</strong><br />
CYP2C9 in altering substrate metabolism<br />
<strong>and</strong> how pharmacogenetics can impact<br />
drug-drug interactions. Work from his<br />
laboratory has demonstrated that reduced<br />
activity allelic variants <strong>of</strong> CYP2C9 can<br />
significantly attenuate drug-drug interaction<br />
potential in humans <strong>and</strong> necessitate<br />
differential alterations in drug dose based<br />
on an individual’s genotype in cases where<br />
interacting drugs must be co-administered.<br />
More recently, this research has examined<br />
the role <strong>of</strong> protein-protein interactions<br />
among the cytochrome P450 enzymes<br />
<strong>and</strong> how these interactions may alter<br />
drug metabolism capacity. The long term<br />
objective <strong>of</strong> Dr. Tracy’s research is to develop<br />
predictive models <strong>of</strong> in vivo human drug<br />
metabolism <strong>and</strong> drug-drug interactions from<br />
in vitro data to improve therapeutic efficacy<br />
<strong>and</strong> minimize toxicity.<br />
20<br />
Awards Program<br />
Jeffry g. weers, ph.d.<br />
nOvArtiS PhArMACeutiCAl COrPOrAtiOn<br />
Evans <strong>and</strong> Wennerström noted that the<br />
colloidal domain is where biology, chemistry,<br />
physics, <strong>and</strong> technology meet. Nowhere is<br />
this more important than in the field <strong>of</strong> drug<br />
delivery. Dr. Weers’ career has focused on<br />
the development <strong>of</strong> engineered particles<br />
for biomedical <strong>and</strong> consumer products.<br />
He is an inventor <strong>of</strong> 40 patents with an<br />
additional 45 published patents pending.<br />
Among his inventions are a blood substitute<br />
formulation based on nanoemulsion droplets<br />
<strong>of</strong> perfluorooctyl bromide (Oxygent),<br />
<strong>and</strong> an ultrasound contrast agent based<br />
on microbubbles <strong>of</strong> perfluorohexane<br />
(Imagent®). More recently, his research has<br />
focused on finding better ways to deliver<br />
drugs via inhalation. In this regard, Dr. Weers<br />
designed aerosol formulations comprising<br />
hollow porous particles (PulmoSphere<br />
technology) for use in portable inhalers.<br />
The PulmoSphere technology was utilized<br />
in the development <strong>of</strong> the TOBI ® Podhaler,<br />
a dry powder formulation <strong>of</strong> tobramycin<br />
for the treatment <strong>of</strong> chronic Pseudomonas<br />
aeruginosa infections in cystic<br />
fibrosis patients.
spEcIal<br />
rEcOgnITIOns<br />
philip r. mayer, ph.d.<br />
AAPS PASt PreSident<br />
wayne r. gombotz, ph.d.<br />
AAPS treASurer<br />
marilyn E. morris, ph.d.<br />
AAPS MeMber-At-lArge<br />
spEcIal rEcOgnITIOns<br />
rEpOrT Of<br />
THE prEsIdEnT<br />
david Y. mitchell, ph.d.<br />
AAPS PreSident<br />
<strong>2012</strong> AAPS Annual Meeting <strong>and</strong> <strong>Exposition</strong> 21
award rEcIpIEnTs<br />
<strong>aaps</strong> research achievement awards<br />
The AAPS Research Achievement Awards are intended to recognize outst<strong>and</strong>ing scientists<br />
who have conducted fundamental research that has had significant impact in the fields <strong>of</strong><br />
Drug Discovery <strong>and</strong> Development Interface (DDDI), Formulation Design <strong>and</strong> Development<br />
(FDD), <strong>and</strong> Pharmacokinetics, Pharmacodynamics <strong>and</strong> Drug Metabolism (PPDM).<br />
<strong>aaps</strong> research achievement<br />
award in drug discovery <strong>and</strong><br />
development Interface<br />
SPOnSOred by Allergan<br />
aleem gangjee, ph.d.<br />
duQueSne univerSity<br />
Some <strong>of</strong> the most important strides against<br />
cancer in the past few years have come from<br />
combination chemotherapy. However, the<br />
use <strong>of</strong> two or more separate agents have<br />
disadvantages such as pharmacokinetic<br />
differences <strong>of</strong> the drugs that may preclude<br />
the concept <strong>of</strong> combination chemotherapy,<br />
cost <strong>of</strong> two or more drugs <strong>and</strong> patient<br />
compliance among others. In an attempt<br />
to circumvent such drawbacks, Dr. Gangjee<br />
<strong>and</strong> co-workers designed, synthesized <strong>and</strong><br />
evaluated single agents with “combination<br />
chemotherapy” attributes. These single<br />
agents target cancer cells at two or more<br />
different sites. The dual <strong>and</strong> multitargeting<br />
single agents that Dr. Gangjee <strong>and</strong><br />
co-workers have developed include<br />
dihydr<strong>of</strong>olate reductase <strong>and</strong> thymidylate<br />
synthase targeting agents; antiangiogenic<br />
<strong>and</strong> thymidylate synthase targeting agents;<br />
antimitotic <strong>and</strong> antiangiogenic agents;<br />
P13K, mTOR <strong>and</strong> purine synthesis inhibitors;<br />
tumor selective folate transport <strong>and</strong> purine<br />
synthesis inhibitors. A number <strong>of</strong> these<br />
rationally designed drugs are in preclinical<br />
development <strong>and</strong> show remarkable efficacy<br />
in in vivo animal tumor xenograft models<br />
<strong>and</strong> are poised for possible clinical trials.<br />
22<br />
Awards Program<br />
Dr. Gangjee will be speaking on Tuesday,<br />
October 16, from 8:30 am – 11:00 am<br />
in Room W185 at the McCormick Place<br />
Convention Center.<br />
<strong>aaps</strong> research achievement award in<br />
formulation design <strong>and</strong> development<br />
SPOnSOred by Pfizer inc.<br />
mansoor a. Khan, r.ph., ph.d.<br />
u.S. fOOd And drug AdMiniStrAtiOn<br />
Dr. Khan is a Senior Biomedical Research<br />
Scientist (SBRS) <strong>and</strong> serves as the Director<br />
<strong>of</strong> Product Quality Research in the Center<br />
for Drug Evaluation <strong>and</strong> Research (CDER)<br />
in FDA. Prior to joining FDA in 2004, Dr.<br />
Khan was a Pr<strong>of</strong>essor <strong>of</strong> Pharmaceutics<br />
<strong>and</strong> Director <strong>of</strong> Graduate Program in the<br />
School <strong>of</strong> Pharmacy at Texas Tech University.<br />
He earned his Ph.D. in Industrial Pharmacy<br />
from the St. John’s University School <strong>of</strong><br />
Pharmacy in 1992. He has published over<br />
210 peer-reviewed manuscripts, four texts,<br />
15 book chapters, <strong>and</strong> has been invited to<br />
give more than 150 presentations worldwide.<br />
Dr. Khan’s research focuses primarily<br />
in the area <strong>of</strong> drug formulations design <strong>and</strong><br />
development <strong>of</strong> “challenging molecules.”<br />
It encompasses pediatric dosage forms,<br />
nanoparticles, modified release dosage<br />
forms, biosimilar characterization, particulate<br />
engineering, <strong>and</strong> scientific underpinnings<br />
<strong>of</strong> Quality by Design utilizing novel Process<br />
Analytical Technologies. As the Director
<strong>of</strong> Product Quality Research, Dr. Khan<br />
serves as CDER’s principal advisor on all<br />
matters related to planning <strong>and</strong> conducting<br />
research to study the impact on product<br />
quality, changes in bulk drug substances,<br />
formulation component <strong>and</strong> composition,<br />
<strong>and</strong> manu-facturing equipment <strong>and</strong><br />
processes.<br />
As a recognized expert, Dr. Khan participates<br />
fully in policy formulation; planning <strong>and</strong><br />
evaluating programs, including oversight<br />
<strong>of</strong> pharmaceutical science activities to<br />
insure that basic <strong>and</strong> original research are<br />
considered in major CDER decisions. He<br />
maintains contact with “state <strong>of</strong> the science”<br />
in order to integrate the most advanced<br />
research theory or practice in the field <strong>of</strong><br />
pharmaceutical science into the Center’s<br />
new, generic, <strong>and</strong> biotech drug programs.<br />
Dr. Khan is an AAPS Fellow, <strong>and</strong> serves<br />
on the editorial board <strong>of</strong> several leading<br />
journals.<br />
Dr. Khan will be speaking on Tuesday,<br />
October 16, from 8:30 am – 12:00 pm<br />
in Room W196 at the McCormick Place<br />
Convention Center.<br />
<strong>aaps</strong> research achievement award in<br />
pharmacokinetics, pharmacodynamics,<br />
<strong>and</strong> drug metabolism<br />
SPOnSOred by Aptalis Pharmaceutical<br />
technologies<br />
Jashvant d. unadkat, ph.d.<br />
univerSity Of wAShingtOn<br />
Dr. Jashvant (Jash) Unadkat’s laboratory has<br />
established an international reputation in<br />
the area <strong>of</strong> mechanisms <strong>of</strong> drug transport,<br />
metabolism <strong>and</strong> drug interactions (DDI)<br />
<strong>and</strong> in the impact <strong>of</strong> physiological <strong>and</strong><br />
pathological changes on these processes.<br />
Translating findings from the bench to<br />
the bedside is a hallmark <strong>of</strong> his laboratory.<br />
award rEcIpIEnTs<br />
His laboratory was the first to measure<br />
P-glycoprotein activity <strong>and</strong> its inhibition at<br />
the human blood-brain barrier (BBB) using<br />
a novel PET imaging technique. Based on<br />
these studies, it is now widely accepted that<br />
inadvertent P-gp DDI at the human BBB are<br />
unlikely to occur except when the drug is<br />
predominately excluded from the brain by<br />
P-gp. In addition, his laboratory has found<br />
that the activity <strong>of</strong> P-gp at the BBB, which<br />
transports beta-amyloid out <strong>of</strong> the brain, is<br />
compromised in Alzheimer’s disease. This<br />
finding could result in novel ways to treat<br />
this disease. Further, Dr. Unadkat’s work has<br />
the potential to increase the effectiveness<br />
<strong>of</strong> drugs in the treatment <strong>of</strong> diseases such<br />
as hepatitis C. Specifically, he has found<br />
that the dosing regimens <strong>of</strong> ribavirin as it<br />
is typically used to treat hepatitis C may<br />
not be optimal because the distribution <strong>of</strong><br />
ribavirin into hepatocytes (the target site)<br />
is saturated.<br />
Dr. Unadkat will be speaking on Tuesday,<br />
October 16, from 8:30 am – 12:00 pm<br />
in Room W184 at the McCormick Place<br />
Convention Center.<br />
<strong>2012</strong> AAPS Annual Meeting <strong>and</strong> <strong>Exposition</strong> 23
award recipients<br />
<strong>aaps</strong> regulatory sciences<br />
achievement award<br />
SPOnSOred by novartis vaccines <strong>and</strong><br />
diagnostics, inc.<br />
Vijay Kumar Tammara, ph.d.<br />
nurOn biOteCh inC.<br />
Dr. Tammara previously served as a Director,<br />
Regulatory Affairs at Merck & Co., Inc., Senior<br />
Associate Director at Wyeth Pharmaceuticals<br />
<strong>and</strong> as an Assistant Director at San<strong>of</strong>i-<br />
Synthelabo in Worldwide Regulatory Affairs.<br />
Prior to his industrial positions, Dr. Tammara<br />
held increasingly responsible positions<br />
in the Office <strong>of</strong> Clinical Pharmacology<br />
<strong>and</strong> Biopharmaceutics at the FDA <strong>and</strong><br />
received several FDA awards including the<br />
CDER Outst<strong>and</strong>ing Reviewer Award, FDA<br />
Outst<strong>and</strong>ing Achievement Award, Group<br />
Recognition Awards, Center Director’s<br />
Special Citation Awards, CDER Team<br />
Excellence Awards, Team Spirit Awards, <strong>and</strong><br />
Awards <strong>of</strong> Excellence. His industrial awards<br />
include Merck’s Awards <strong>of</strong> Excellence in<br />
2004, 2005, 2007, 2009, <strong>and</strong> 2010 <strong>and</strong><br />
Special Recognition Awards in 2007, 2008,<br />
2009, <strong>and</strong> 2010. He is also the recipient <strong>of</strong><br />
the AAPS RS Section Recognition Awards<br />
in 2004, 2007 <strong>and</strong> 2008. He also received<br />
the 2009 Distinguished Scientist Award<br />
from the <strong>American</strong> <strong>Association</strong> <strong>of</strong> Indian<br />
Pharmaceutical Scientists.<br />
24<br />
Awards Program<br />
dale E. wurster research award<br />
in pharmaceutics<br />
SPOnSOred by dale eric <strong>and</strong> Pamela A.<br />
wurster/Susan wurster biel<br />
The purpose <strong>of</strong> this award is to recognize<br />
individuals who have made significant<br />
research contributions to the pharmaceutical<br />
sciences in the specific field <strong>of</strong><br />
pharmaceutics.<br />
Bradley d. <strong>and</strong>erson, ph.d.<br />
univerSity Of KentuCKy<br />
Dr. Anderson focuses on mechanismbased<br />
predictive relationships linking<br />
drug molecular structure, speciation,<br />
<strong>and</strong> intermolecular interactions to<br />
pharmaceutically relevant physical<br />
properties such as solubility <strong>and</strong><br />
solubilization in formulations, chemical<br />
& physical stability <strong>of</strong> solutions <strong>and</strong><br />
amorphous solids, <strong>and</strong> membrane<br />
transport/drug delivery. His research<br />
combines experimental studies, molecular<br />
dynamics computer simulations, <strong>and</strong><br />
mathematical model development<br />
founded on physical <strong>and</strong> physical organic<br />
chemistry to underst<strong>and</strong> <strong>and</strong> optimize<br />
drug developability, formulation quality,<br />
<strong>and</strong> delivery system performance. Several<br />
prodrugs or delivery systems designed or<br />
explored in Dr. Anderson’s laboratories have<br />
been patented <strong>and</strong> some have advanced<br />
to clinical studies or commercialization.<br />
Biophysical insights <strong>and</strong> quantitative<br />
relationships between passive membrane<br />
transport <strong>and</strong> structure stemming from his<br />
investigations <strong>of</strong> drug permeability across<br />
lipid bilayer membranes have advanced<br />
underst<strong>and</strong>ing <strong>of</strong> drug transport across<br />
biomembrane barriers including the skin,<br />
oral mucosa, <strong>and</strong> blood-brain barrier <strong>and</strong> led<br />
to the design <strong>of</strong> lipid-based drug delivery<br />
systems with tunable drug release kinetics<br />
for cancer chemotherapy. Recently, he has
contributed to a mechanistic underst<strong>and</strong>ing<br />
<strong>of</strong> the chemical <strong>and</strong> physical stability <strong>of</strong><br />
amorphous solid formulations by taking<br />
into account mobility effects on competing<br />
pathways governing the fate <strong>of</strong> reactive<br />
intermediates during chemical degradation<br />
<strong>and</strong> utilizing molecular dynamics computer<br />
simulations to explore specific drugexcipient<br />
interactions governing physical<br />
stability <strong>and</strong> performance.<br />
distinguished service award<br />
SPOnSOred by San<strong>of</strong>i<br />
The AAPS Distinguished Service Award<br />
is intended to recognize distinguished<br />
service in advancing the pharmaceutical<br />
sciences <strong>and</strong> the <strong>American</strong> <strong>Association</strong> <strong>of</strong><br />
Pharmaceutical Scientists.<br />
larry l. augsburger, ph.d.<br />
university <strong>of</strong> Maryl<strong>and</strong><br />
Dr. Augsburger is an internationally<br />
recognized researcher in pharmaceutics, the<br />
broad pharmaceutical science community,<br />
as well as in the fields <strong>of</strong> process engineering<br />
<strong>and</strong> the formulation <strong>and</strong> control <strong>of</strong> dietary<br />
supplements. His research has contributed<br />
to the basic science underpinning oral solid<br />
dosage form fabrication <strong>and</strong> quality, <strong>and</strong> to<br />
the practice <strong>of</strong> manufacture <strong>and</strong> regulation<br />
<strong>of</strong> these products. His research thus deals<br />
with a highly important aspect <strong>of</strong> material<br />
sciences that has direct relevance to public<br />
health with respect to both drugs <strong>and</strong> dietary<br />
supplements. Supported by more than $13.5<br />
million in grants <strong>and</strong> contracts from the NIH,<br />
FDA <strong>and</strong> private industry, his work has been<br />
recognized by a number <strong>of</strong> awards, among<br />
which are the Federation Internationale<br />
Pharmaceutique (FIP) Industrial Pharmacy<br />
Medal, the AAPS Dale E. Wurster Research<br />
Award in Pharmaceutics, <strong>and</strong> the Dr. Patricia<br />
award recipients<br />
Sokolove Outst<strong>and</strong>ing Mentor Award for<br />
his work with graduate students. A charter<br />
member <strong>of</strong> AAPS, Dr. Augsburger has a<br />
long <strong>and</strong> distinguished record <strong>of</strong> service to<br />
AAPS <strong>and</strong> was the 1999 AAPS president. His<br />
research achievements combined with his<br />
dedicated service to AAPS have significantly<br />
<strong>and</strong> meaningfully advanced both the<br />
pharmaceutical sciences <strong>and</strong> the <strong>American</strong><br />
<strong>Association</strong> <strong>of</strong> Pharmaceutical Scientists.<br />
<strong>2012</strong> AAPS Annual Meeting <strong>and</strong> <strong>Exposition</strong> 25
OpEnIng sEssIOn<br />
IncOmIng prEsIdEnT’s<br />
rEmarKs<br />
anthony J. destefano, ph.d.<br />
AAPS PreSident-eleCt<br />
spEcIal rEcOgnITIOn<br />
colin m. minchom, ph.d.<br />
<strong>2012</strong> AnnuAl Meeting PrOgrAM ChAir<br />
Introduction <strong>of</strong> <strong>2012</strong> <strong>annual</strong> <strong>meeting</strong><br />
program committee<br />
Colin M. Minchom, Ph.D. (Chair)<br />
Christopher R. McCurdy, Ph.D. (Chair-elect)<br />
Elizabeth de Lange, Ph.D. (2013 Chair-elect)<br />
Anthony J. DeStefano, Ph.D. (Past Chair)<br />
Stephen T. Colgan, Ph.D. (APQ Section)<br />
William Nowatzke, Ph.D. (BIOTEC Section)<br />
Thaddeus H. Grasela, Pharm. D., Ph.D.<br />
(CPTR Section)<br />
Annette Bak, Ph.D., MBA (DDDI Section)<br />
Lavinia Marina Lewis, Ph.D. (FDD Section)<br />
Cynthia A. Oksanen, Ph.D. (MSE Section)<br />
Ping Gao, Ph.D. (PPB Section)<br />
Joseph W. Polli, Ph.D. (PPDM Section)<br />
Ganapathy Mohan, Ph.D. (RS Section)<br />
Russell S. Weiner, Ph.D. (EC Liaison)<br />
26<br />
Awards Program<br />
KEYnOTE addrEss<br />
rebecca skloot<br />
AuthOr; fOunder And PreSident Of the<br />
henriettA lACKS fOundAtiOn<br />
Bestselling author Rebecca Skloot spent<br />
over ten years doggedly uncovering the<br />
truth about the life, death, <strong>and</strong> ultimate<br />
“immortality” <strong>of</strong> a poor black tobacco<br />
farmer named Henrietta Lacks. In The<br />
Immortal Life <strong>of</strong> Henrietta Lacks, Skloot<br />
tells the narrative <strong>of</strong> a young black<br />
woman who died <strong>of</strong> cervical cancer in<br />
1951—<strong>and</strong> left behind an inexplicably<br />
immortal line <strong>of</strong> cells known as HeLa.<br />
Henrietta Lacks, whose cells—harvested<br />
without her knowledge or consent—<br />
contributed to scientific advancements as<br />
varied as the polio vaccine, treatments for<br />
cancers <strong>and</strong> viruses, in vitro fertilization,<br />
<strong>and</strong> the impact <strong>of</strong> space travel on human<br />
cells. Part detective story, part scientific<br />
odyssey, <strong>and</strong> part family saga, the book’s<br />
multi-layered approach raises fascinating<br />
questions about race, class, <strong>and</strong> bioethics<br />
in America.<br />
Though best-known for The Immortal<br />
Life <strong>of</strong> Henrietta Lacks, Rebecca Skloot<br />
has written more than 200 feature<br />
articles, personal essays, book reviews,<br />
<strong>and</strong> news stories for The New York<br />
Times Magazine; O, The Oprah Magazine;<br />
Discover; Columbia Journalism Review;<br />
Seed; New Yorker Magazine; Slate;<br />
Popular Science; Chicago Tribune; <strong>and</strong><br />
other publications.<br />
Rebecca Skloot has a B.S. in biological<br />
sciences <strong>and</strong> a MFA in creative<br />
nonfiction. She has taught creative<br />
writing <strong>and</strong> science journalism at the<br />
University <strong>of</strong> Memphis, the University <strong>of</strong><br />
Pittsburgh, <strong>and</strong> New York University. She<br />
is founder <strong>and</strong> president <strong>of</strong> the Henrietta<br />
Lacks Foundation.
InTrOducTIOn Of THE<br />
2013 <strong>aaps</strong> ExEcuTIVE cOuncIl<br />
anthony J. destefano, ph.d.<br />
PreSident<br />
marilyn E. morris, ph.d.<br />
PreSident-eleCt<br />
david Y. mitchell, ph.d.<br />
iMMediAte PASt PreSident<br />
phillip ramsey, m.B.a., r.a.c.<br />
treASurer<br />
James E. polli, ph.d. (2013)<br />
MeMber-At-lArge<br />
raman Venkataramanan, ph.d. (2013)<br />
MeMber-At-lArge<br />
dannette K. doolittle, ph.d. (2014)<br />
MeMber-At-lArge<br />
russell s. weiner, ph.d. (2014)<br />
MeMber-At-lArge<br />
Binodh s. desilva, ph.d. (2015)<br />
MeMber-At-lArge<br />
<strong>2012</strong> AAPS Annual Meeting <strong>and</strong> <strong>Exposition</strong> 27
<strong>aaps</strong> awards HIsTOrY<br />
<strong>aaps</strong> distinguished pharmaceutical<br />
scientist award<br />
1989 Leslie Z. Benet, Ph.D.<br />
1991 Dale E. Wurster, Ph.D.<br />
1993 Robert S. Langer, Sc.D.<br />
1995 George Zografi, Ph.D.<br />
1997 Ronald T. Borchardt, Ph.D.<br />
1999 Joseph R. Robinson, Ph.D.<br />
2001 Wolfgang Sadée, Ph.D.<br />
2003 Yuichi Sugiyama, Ph.D.<br />
2005 Gordon L. Amidon, Ph.D.<br />
2007 Nicholas S. Bodor, Ph.D.<br />
2009 Michael J. Pikal, Ph.D.<br />
2011 Valentino J. Stella, Ph.D.<br />
<strong>aaps</strong> dale E. wurster research award<br />
1990 George Zografi, Ph.D.<br />
1992 Gerhard Levy, Pharm.D.<br />
1994 William I. Higuchi, Ph.D.<br />
1996 Joseph R. Robinson, Ph.D.<br />
1998 Sung Wan Kim, Ph.D.<br />
2000 Leslie Z. Benet, Ph.D.<br />
2002 Nicholas A. Peppas, Sc.D., D.Eng.<br />
2004 David J. W. Grant, Ph.D.<br />
2006 Patrick P. DeLuca, Ph.D.<br />
2008 Larry Augsburger, Ph.D.<br />
2010 Theodore W. R<strong>and</strong>olph, Ph.D.<br />
<strong>2012</strong> Brad Anderson, Ph.D.<br />
<strong>aaps</strong> distinguished service award<br />
1990 Klaus G. Florey, Ph.D.<br />
1992 Karl A. DeSante, Ph.D.<br />
1994 Wolfgang Sadée, Ph.D.<br />
1996 Leslie Z. Benet, Ph.D.<br />
1998 Vincent H.L. Lee, Ph.D.<br />
2000 Vinod P. Shah, Ph.D.<br />
2002 Jerome P. Skelly, Ph.D.<br />
2004 Richard F. Bergstrom, Ph.D.<br />
2006 Mario L. Rocci, Jr., Ph.D.<br />
2008 Sathyanarayana (Satyam) M.<br />
Upadrashta, Ph.D., RAC<br />
2010 Ho-Leung Fung, Ph.D.<br />
<strong>2012</strong> Larry L. Augsburger, Ph.D.<br />
research achievement award in analysis<br />
<strong>and</strong> pharmaceutical Quality<br />
1988 John C. Craig, Ph.D.<br />
1990 James T. Stewart, Ph.D.<br />
1992 Kamal K. Midha, Ph.D.<br />
1994 William D. Mason, Ph.D.<br />
1996 H. Thomas Karnes, Ph.D.<br />
1998 Harry G. Brittain, Ph.D.<br />
2000 Peter Kissinger, Ph.D.<br />
2003 Bogdan Matuszewski, Ph.D.<br />
2004 Susan M. Lunte, Ph.D.<br />
2006 Mohammed Jemal, Ph.D.<br />
2008 Craig Lunte, Ph.D.<br />
2010 Michael G. Bartlett, Ph.D.<br />
28<br />
Awards Program<br />
<strong>aaps</strong> research achievement award<br />
in Biotechnology<br />
1991 Wolfgang Sadée, Ph.D.<br />
1993 Ronald T. Borchardt, Ph.D.<br />
1997 Mark C. Manning, Ph.D.<br />
1999 Charles R. Middaugh, Ph.D.<br />
2001 Francis C. Szoka, Ph.D.<br />
2003 Victor C. Yang, Ph.D.<br />
2005 Richard D. DiMarchi, Ph.D.<br />
2007 John F. Carpenter, Ph.D.<br />
2009 David Scott, Ph.D.<br />
<strong>aaps</strong> research achievement award in<br />
clinical pharmacology <strong>and</strong> Translational<br />
research (formerly clinical sciences)<br />
1991 Jerome J. Schentag, Pharm.D.<br />
1995 Daniel L. Azarn<strong>of</strong>f, M.D.<br />
1997 Roger Jelliffe, Ph.D.<br />
1998 Milap C. Nahata, MS, Pharm.D.<br />
2004 Hartmut Derendorf, Ph.D.<br />
2005 David J. Greenblatt, M.D.<br />
2007 Nick Holford, M.D., M.B., Ch.B.<br />
2009 Mark J. Ratain, MD<br />
2011 Jeffrey Barrett, Ph.D., FCP<br />
<strong>aaps</strong> research achievement<br />
award in Economic, marketing <strong>and</strong><br />
management sciences<br />
1990 Mickey C. Smith, Ph.D.<br />
1992 Charles D. Hepler, Ph.D.<br />
1994 Andy S. Stergachis, Ph.D.<br />
1996 J. Lyle Bootman, Ph.D.<br />
1998 Jeffrey A. Kotzan, Ph.D.<br />
2000 Dev S. Pathak, DBA<br />
<strong>aaps</strong> research achievement award in<br />
drug discovery <strong>and</strong> development Interface<br />
(formerly drug design <strong>and</strong> discovery)<br />
1988 Nicholas S. Bodor, Ph.D.<br />
1990 Philip S. Portoghese, Ph.D.<br />
1992 Daniel H. Rich, Ph.D.<br />
1994 Ronald T. Borchardt, Ph.D.<br />
1996 Ralph F. Hirschmann, Ph.D.<br />
1998 Kenner C. Rice, Ph.D.<br />
2000 Peter W. Schiller, Ph.D.<br />
2002 Alex<strong>and</strong>ros Makriyannis, Ph.D.<br />
2004 Rao S. Rapaka, Ph.D.<br />
2006 F. Ivy Carroll, Ph.D.<br />
2008 Lemont B. Kier, Ph.D.<br />
2010 Peter A. Crooks, Ph.D.<br />
<strong>2012</strong> Aleem Gangjee, Ph.D.<br />
<strong>aaps</strong> research achievement award in<br />
formulation design <strong>and</strong> development<br />
2010 Abu T. M. Serajuddin, Ph.D.<br />
<strong>2012</strong> Mansoor A. Khan, R.Ph., Ph.D.
<strong>aaps</strong> research achievement award in<br />
manufacturing science & Engineering<br />
2009 Dale Eric Wurster, Ph.D.<br />
2011 Ahmed Adel Sakr, Ph.D.<br />
<strong>aaps</strong> research achievement award in<br />
pharmaceutics <strong>and</strong> drug delivery<br />
1988 William I. Higuchi, Ph.D.<br />
1989 Arm<strong>and</strong>o J. Aguiar, Ph.D.<br />
1991 Joseph R. Robinson, Ph.D.<br />
1993 Felix Theeuwes, D.Sc.<br />
1995 Sung Wan Kim, Ph.D.<br />
1997 Valentino J. Stella, Ph.D.<br />
1999 Tsuneji Nagai, Ph.D.<br />
2001 Kinam Park, Ph.D.<br />
2003 Vincent H.L. Lee, Ph.D.<br />
2005 Vladimir P. Torchilin, Ph.D.<br />
2007 Mitsuru Hashida, Ph.D.<br />
<strong>aaps</strong> research achievement award<br />
in pharmacokinetics, pharmacodynamics<br />
<strong>and</strong> drug metabolism<br />
1988 Ho-Leung Fung, Ph.D.<br />
1990 Edward R. Garrett, Ph.D.<br />
1992 John G. Wagner, Ph.D.<br />
1994 Malcolm Rowl<strong>and</strong>, Ph.D.<br />
1996 Milo Gibaldi, Ph.D.<br />
1998 William J. Jusko, Ph.D.<br />
2000 Grant R. Wilkinson, Ph.D.<br />
2002 K. S<strong>and</strong>y Pang, Ph.D.<br />
2004 Jessie L-S. Au, Ph.D.<br />
2006 Kathleen Giacomini, Ph.D.<br />
2008 Ken-ichi Inui, Ph.D.<br />
2010 Meindert Danh<strong>of</strong>, Ph.D<br />
<strong>2012</strong> Jashvant D. Unadkat, Ph.D.<br />
<strong>aaps</strong> research achievement award in<br />
pharmaceutical Technologies<br />
1988 Patrick P. DeLuca, Ph.D.<br />
1989 Ralph F. Shangraw, Ph.D.<br />
1991 Stanley L. Hem, Ph.D.<br />
1993 Hans Leuenberger, Ph.D.<br />
1995 Eugene L. Parrott, Ph.D.<br />
1997 J. Keith Guillory, Ph.D.<br />
1999 Nicholas A. Peppas, Sc.D., D.Eng.<br />
2001 Michael J. Pikal, Ph.D.<br />
2003 Larry L. Augsburger, Ph.D.<br />
2005 James W. McGinity, Ph.D.<br />
2007 Steven L. Nail, Ph.D.<br />
<strong>aaps</strong> regulatory sciences<br />
achievement award<br />
2004 Jerome P. Skelly, Ph.D.<br />
2006 Ajaz S. Hussain, Ph.D.<br />
2008 Moheb M. Nasr, Ph.D.<br />
2010 Sathyanarayana (Satyam) Upadrashta,<br />
Ph.D., RAC<br />
<strong>2012</strong> Vijay Tammara, Ph.D.<br />
<strong>aaps</strong> awards HIsTOrY<br />
<strong>aaps</strong> lipid-based drug delivery<br />
Outst<strong>and</strong>ing research award<br />
2005 Anette Müllertz, Ph.D.<br />
2006 Russell J. Mumper, Ph.D.<br />
2007 Kishor M. Wasan, Ph.D.<br />
2008 Hayat Onyuksel, Ph.D.<br />
2009 Christopher J.H. Porter, Ph.D.<br />
2011 Ben Boyd, Ph.D.<br />
<strong>aaps</strong> Excellence in lig<strong>and</strong> Binding assays<br />
2004 Jason Pennucci<br />
Steven Swanson, Ph.D.<br />
Shalini Gupta, Ph.D.<br />
2005 Lin Yang<br />
Stephanie Sidobre, Ph.D.<br />
L. Kelly<br />
C. Cooper<br />
M. Khan<br />
2006 F. Nabbie<br />
S. Chang<br />
G. Schieven<br />
R. Zhang<br />
J. Kelsey<br />
R. Weiner<br />
Y. Barrett<br />
2007 Joan Kelsey<br />
2008 Daniel J. Baltrukonis<br />
Thomas Kawabata<br />
Deborah Finco-Kent<br />
2009 Susan Jacques<br />
Shalini Gupta<br />
Steve Swanson<br />
Arunan Kaliyaperumal<br />
2010 Ray Yin<br />
Yli Vallejo<br />
Jing Pan<br />
Thomas Small<br />
Dujie Qin<br />
Dave Chen<br />
2011 Murli Krishna<br />
Alex<strong>and</strong>er Kozhich<br />
Suk Kwok<br />
Zhen Lou<br />
Paul Rhyne<br />
<strong>2012</strong> Jay Wustner<br />
MaryLou Dula<br />
Shawn Fern<strong>and</strong>o<br />
Katie Bendas<br />
Yun Liu<br />
Danielle Horgan<br />
Dan Hanrahan<br />
Megan Kuc<br />
Dongzhao Chen<br />
Michael Deitrich<br />
Estie VanVolkenburgh<br />
Reannon Holl<strong>and</strong><br />
Wolfgang Ebel<br />
Philip Sass<br />
Nicholas Niclaides<br />
<strong>2012</strong> AAPS Annual Meeting <strong>and</strong> <strong>Exposition</strong> 29
<strong>aaps</strong> awards HIsTOrY<br />
<strong>aaps</strong> meritorious manuscript award<br />
1990 Bradley D. Anderson, Ph.D.<br />
Prakash V. Raykar, Ph.D.<br />
Man-Cheong Fung, Ph.D.<br />
1991 Ronald T. Borchardt, Ph.D.<br />
Kevin R. Smith<br />
1992 Noboru Yata, Ph.D.<br />
Toshihiko Toyoda, Ph.D.<br />
Teruo Murakami, Ph.D.<br />
Akio Nishiura, Ph.D.<br />
Yutaka Higashi, Ph.D.<br />
1994 Philip S. Burton, Ph.D.<br />
Robert A. Conradi, Ph.D.<br />
Allen R. Hilgers<br />
Norman F.H. Ho, Ph.D.<br />
1995 P.K. Tsai, Ph.D.<br />
David B. Volkin, Ph.D.<br />
Jonathan M. Dabora<br />
Karen C. Thompson, Ph.D.<br />
Mark W. Bruner<br />
Jacqueline O. Gress<br />
Bozena Matuszewska, Ph.D.<br />
Martina Keogan<br />
Joseph V. Bondi, Ph.D.<br />
C. Russell Middaugh, Ph.D.<br />
1996 Akira Tsuji, Ph.D.<br />
Tetsuya Terasaki, Ph.D.<br />
Ikumi Tamai, Ph.D.<br />
Hitomi Takanaga, Ph.D.<br />
1997 William M. Pardridge, M.D.<br />
Young Sook Kang, Ph.D.<br />
Jody L. Buciak<br />
Jing Yang<br />
1998 Manoj M. Nerurkar, Ph.D.<br />
Philip S. Burton, Ph.D.<br />
Ronald T. Borchardt, Ph.D.<br />
1999 Zheng Yang, Ph.D.<br />
Richard C. Brundage, Ph.D., Pharm.D.<br />
Rashmi H. Barbhaiya, Ph.D.<br />
Ronald J. Sawchuk, Ph.D.<br />
2000 Ahmed El-Tahtawy<br />
Thomas Tozer, Ph.D.<br />
Ferrin Harrison<br />
Larry Lesko, Ph.D.<br />
Roger Williams, M.D.<br />
2001 Neville M. Concessio<br />
Michiel M. Van Oort, Ph.D.<br />
Michael R. Knowles<br />
Anthony J. Hickey, Ph.D.<br />
2002 Cynthia Brimer Cline<br />
James T. Dalton, Ph.D.<br />
Zixon Zhu<br />
John Schuetz, Ph.D.<br />
Kazuto Yasuda<br />
Elio Vanin<br />
Mary V. Relling, Pharm.D.<br />
Yi Lu<br />
Erin G. Schuetz<br />
2003 Wiliam M. Pardridge, M.D.<br />
Ruben J. Boado<br />
Ningya Shi<br />
30<br />
Awards Program<br />
2004 Duxin Sun<br />
Hans Lennernäs, Ph.D.<br />
Lynda S. Welage, Pharm D., FCCP<br />
Jeffery L. Barnett<br />
Christopher P. L<strong>and</strong>owski<br />
David Foster<br />
David Fleisher, Ph.D.<br />
Kyung-Dall Lee, Ph.D.<br />
Gordon L. Amidon, Ph.D.<br />
2005 Per Artusson, Ph.D.<br />
Saeho Chong, Ph.D.<br />
Rick Morrison, Ph.D.<br />
Lauri Söderberg<br />
Jan Taipalensuu<br />
Staffan Tavelin<br />
2006 Jennifer Smith<br />
Edward Wood<br />
Michael Dornish<br />
2007 Goldie Kaul<br />
Mansoor M. Amiji, Ph.D.<br />
2008 William J. Jusko<br />
Zhenling Yao<br />
Debra C. DuBois<br />
Richard R. Almon<br />
<strong>aaps</strong> pharmaceutical research meritorious<br />
manuscript award (formerly <strong>aaps</strong><br />
meritorious manuscript award)<br />
2009 Gary M. Pollack, Ph.D.<br />
John C. Kalvass<br />
2010 Tetsuya Terasaki<br />
Junichi Kamiie<br />
Sumio Ohtsuki<br />
Ryo Iwase<br />
Ken Ohmine<br />
Yuki Katsukura<br />
Kazunari Yanai<br />
Yumi Sekine<br />
Yasuo Uchida<br />
Shingo Ito<br />
2011 Par Matsson<br />
Jenny M. Pedersen<br />
Ulf Norinder<br />
Christel A.S. Bergstrom<br />
Per Artursson<br />
<strong>2012</strong> David E. Alonzo, Ph.D.<br />
Ge<strong>of</strong>f G.Z. Zhang, Ph.D.<br />
Deliang Zhou, Ph.D.<br />
Yi Gao, Ph.D.<br />
Lynne S. Taylor, Ph.D.<br />
<strong>aaps</strong> Outst<strong>and</strong>ing Educator award<br />
2000 Patrick P. DeLuca, Ph.D.<br />
2002 George Zografi, Ph.D.<br />
2004 Larry L. Augsburger, Ph.D.<br />
2006 Joseph B. Schwartz, Ph.D.<br />
2008 Adel Sakr, Ph.D.<br />
2010 Raj Suryanarayanan (Sury), Ph.D.<br />
<strong>2012</strong> John L. Neumeyer, Ph.D.
<strong>aaps</strong> Outst<strong>and</strong>ing manuscript award in<br />
analysis <strong>and</strong> pharmaceutical Quality<br />
1997 Perry A. Hailey, Ph.D.<br />
Phil Doherty<br />
Paul Tapsell<br />
Timothy Oliver<br />
Paul K. Aldridge<br />
1998 Keith K. Burton<br />
Jeremy R. Everett<br />
Michael J. Newman<br />
Frank S. Pullen<br />
Don S. Richards<br />
Alistair G. Swanson<br />
1999 Shewan M. Aziz, R.Ph., Ph.D.<br />
Mustafa Yatin, Ph.D.<br />
David R Worthen, R.Ph., MS, DRW<br />
David W. Lipke, Ph.D.<br />
Peter A. Crooks, Ph.D.<br />
2000 Sean X. Peng, Ph.D.<br />
Babul Borah, Ph.D.<br />
Roy L.M. Dobson, Ph.D.<br />
Y. Diana Liu, Ph.D.<br />
Stanislaw Pikul, Ph.D.<br />
2001 Jacob Bongers, Ph.D.<br />
John J. Cummings<br />
Mary Beth Ebert<br />
M. Marcia Federici, Ph.D.<br />
Linden Gledhill, Ph.D.<br />
Dipti Gulati, Ph.D.<br />
George M. Hilliard, Ph.D.<br />
Brian H. Jones<br />
Kwan R. Lee, Ph.D.<br />
Jacek Mozdzanowski, Ph.D.<br />
Michael Naimoli<br />
Sudhir Burman, Ph.D.<br />
2002 Tim Schenk<br />
H. Irth<br />
György Marko-Varga, Ph.D.<br />
L-E. Edholm<br />
U.R. Tjaden<br />
Jan van der Greef<br />
2003 Dannette Hansen-Doolittle, Ph.D.<br />
Dennis O. Scott, Ph.D.<br />
Kenneth W. Otis<br />
Susan M. Lunte, Ph.D.<br />
2004 Ute Gerhard, Ph.D.<br />
Steven Thomas<br />
Russell Mortishire-Smith<br />
2005 Eva Lenz, Ph.D.<br />
Jonathan D. Bright, Ph.D.<br />
Ian D. Wilson, Ph.D.<br />
Andrew Hughes, Ph.D.<br />
Henrik Lindberg, Ph.D.<br />
Andrew J. Locton, Ph.D.<br />
2006 Peter L.D. Wildfong<br />
Nicole A. Morley<br />
Michael D. Moore<br />
Kenneth R. Morris, Ph.D.<br />
<strong>aaps</strong> awards HIsTOrY<br />
2007 Bryan H. Huynh<br />
Barbara A. Fogarty<br />
Prady<strong>of</strong> N<strong>and</strong>i<br />
Susan M. Lunte, Ph.D.<br />
2008 Yuerong Hu<br />
Håkan Wikström<br />
Stephen R. Byrn<br />
Lynne S. Taylor<br />
2009 Kyung H. Gahm<br />
Helming Tan<br />
Jodi Liu<br />
Wesley Barnhart<br />
John Eschelbach<br />
Steve Notari<br />
Samuel Thomas<br />
David Semin<br />
Janet Cheetham<br />
<strong>2012</strong> Raj Suryanarayanan, Ph.D.<br />
Kapildev K. Arora, Ph.D.<br />
Nitin G. Tayade, Ph.D.<br />
<strong>aaps</strong> Outst<strong>and</strong>ing manuscript award<br />
in PharmSciTech (formerly Outst<strong>and</strong>ing<br />
manuscript in pharmaceutical development<br />
<strong>and</strong> Technology)<br />
1998 Srinivas S. Duggirala, Ph.D.<br />
Rahul C. Mehta, Ph.D.<br />
Patrick P. DeLuca, Ph.D.<br />
2000 Wei-Qin (Tony)Tong<br />
Graham Whitsell<br />
2002 Janusz W. Kostanski, Ph.D.<br />
Patrick P. DeLuca, Ph.D.<br />
2004 Ch<strong>and</strong>ra Vemavarapu, Ph.D.<br />
Matthew J. Mollan, Ph.D.<br />
Thomas E. Needham, Ph.D.<br />
2006 Susan D’Souza<br />
Jabar Faraj, Ph.D.<br />
Patrick P. DeLuca, Ph.D.<br />
2008 Ambikan<strong>and</strong>an Misra (Lead Author)<br />
Tushar K. Vyas<br />
A.K. Babbar<br />
Rakesh K. Sharma<br />
Shashi Singh<br />
2010 Svetlana Lyapustina<br />
Steven Novick<br />
David Christopher<br />
Monisha Dey<br />
Michael Golden<br />
Stefan Leiner<br />
Bruce Wyka<br />
Hans-Joachim Delzeit<br />
Chris Novack<br />
Gregory Larner<br />
<strong>2012</strong> AAPS Annual Meeting <strong>and</strong> <strong>Exposition</strong> 31
<strong>aaps</strong> awards HIsTOrY<br />
<strong>aaps</strong> Journal manuscript award (formerly<br />
<strong>aaps</strong> PharmSci manuscript award)<br />
2003 Michael H. Qvist<br />
Ulla Hoeck<br />
Bo Kreilgaard, Ph.D.<br />
Flemming Madsen, Ph.D.<br />
Lars Hovgaard, Ph.D.<br />
Sven Frokjaer, Ph.D.<br />
2005 James D. Andya<br />
Chung C. Hsu, Ph.D.<br />
Steven J. Shire, Ph.D.<br />
2007 Siddhesh D. Patil, Ph.D.<br />
David G. Rhodes, Ph.D.<br />
Diane J. Burgess, Ph.D.<br />
2009 Vladimir P. Torchilin, Ph.D.<br />
2011 Ayman El-Sayed<br />
Shiroh Futaki<br />
Hideyoshi Harashima<br />
<strong>aaps</strong> Outst<strong>and</strong>ing manuscript in modeling<br />
<strong>and</strong> simulation award<br />
2008 Kaori Ito<br />
Matt M Hutmacher<br />
Jing Liu<br />
Ruolun Qiu<br />
Bill Frame<br />
Raymond Miller<br />
2009 Dhaval K. Shah<br />
Beom Soo Shin<br />
Jean Veith<br />
Karoly Toth<br />
Ralph J. Bernacki<br />
Joseph P. Balthasar<br />
2010 Eric Snoeck<br />
Karin Jorga<br />
Pascal Chanu<br />
Mark Lavielle<br />
Philippe Jacqmin<br />
E Niclas Jonsson<br />
Timothy Goggin<br />
Joseph Grippo<br />
N. L’ntshotshole Shasha Jumbe<br />
Nicolas Frey<br />
<strong>2012</strong> Paulo Paixão<br />
José A.G. Morais<br />
Luís F. Gouveia<br />
<strong>aaps</strong> PharmSci & <strong>aaps</strong> PharmSciTech<br />
Outst<strong>and</strong>ing use <strong>of</strong> Technology award<br />
2003 Keith D. Jensen<br />
Pavla Kopecková<br />
John H.B. Bridge<br />
Jindrich Kopecek<br />
32<br />
Awards Program<br />
<strong>aaps</strong> new Investigator grant in<br />
pharmaceutics <strong>and</strong> the pharmaceutical<br />
Technologies<br />
1987 Ronald A. Siegel, Sc.D.<br />
1988 Elizabeth Topp, Ph.D.<br />
1989 Ashim K. Mitra, Ph.D.<br />
1990 Anthony J. Hickey, Ph.D.<br />
1991 Timothy S. Wiedmann, Ph.D.<br />
1992 Yongyut Rojanasakul, Ph.D.<br />
1993 Patrick J. Sinko, Ph.D.<br />
1994 Jane Pei-Fan Bai, Ph.D.<br />
1995 Paul M. Bummer, Ph.D.<br />
1996 Susanna Wu-Pong, Ph.D.<br />
1997 Uday B. Kompella, Ph.D.<br />
1998 James E. Polli, Ph.D.<br />
1999 Jeffrey Hughes, Ph.D.<br />
2000 Peter W. Swaan, Ph.D.<br />
2001 Kishor M. Wasan, Ph.D.<br />
2002 Tonglei Li, Ph.D.<br />
2003 Lynne S. Taylor, Ph.D.<br />
2004 Abdul W. Basit, Ph.D.<br />
2005 Christopher J. Roberts<br />
2006 Karen Hapgood, Ph.D.<br />
2007 Hugh D. Smyth, Ph.D.<br />
2008 Changquan (Calvin) Sun, Ph.D.<br />
2009 Yoon Yeo, Ph.D.<br />
2010 Jerry Y. Y. Heng, Ph.D.<br />
2011 Kun Cheng, Ph.D.<br />
<strong>2012</strong> Seungpyo Hong, Ph.D.<br />
<strong>aaps</strong> new Investigator grant in<br />
pharmacokinetics, pharmacodynamics<br />
<strong>and</strong> drug metabolism<br />
1992 Kathleen M. Boje, Ph.D.<br />
1994 An-Ng (Tony) Kong, Ph.D.<br />
1996 Deanna L. Kroetz, Ph.D.<br />
1998 David R. Taft, Ph.D.<br />
2000 Bernd Meibohm, Ph.D.<br />
2002 Lane J. Brunner, Ph.D.<br />
2005 Carolyn A. Fairbanks<br />
2007 Donald E. Mager, Ph.D.<br />
2009 Swati V. Nagar<br />
2011 Patrick Thomas Ronaldson, Ph.D.<br />
<strong>aaps</strong> new Investigator grant in Oral<br />
lipids-based drug delivery systems<br />
1999 Christopher J. H. Porter, Ph.D.<br />
2001 Ijeoma F. Uchegbu, Ph.D.<br />
2002 Xiaochen Gu
<strong>aaps</strong> postdoctoral fellow<br />
1999 Sheri L. Shamblin, Ph.D.<br />
2000 Wolfgang Jacobsen, Ph.D.<br />
2002 Yurong Lai, Ph.D.<br />
2003 Ramapuram Jayach<strong>and</strong>ra Babu<br />
2004 Siddhesh D. Patil, Ph.D.<br />
2005 Vanessa M. D’Souza<br />
2006 Mo Yun<br />
2007 Carolyn Cummins, Ph.D.<br />
Heidi M. Mansour, Ph.D., R.Ph.<br />
2008 Udaya Toti, Ph.D.<br />
2009 Ch<strong>and</strong>rasekar Durairaj, Ph.D.<br />
Christina Kriegel, Ph.D.<br />
2010 Bernard Van Eerdenbrugh, Ph.D.<br />
2011 Limin Shi, Ph.D.<br />
<strong>2012</strong> Courtney Sloan, Ph.D.<br />
<strong>aaps</strong> drug delivery Technology award<br />
2008 John T. Santini, Jr., Ph.D.(Lead<br />
researcher)<br />
Elizabeth Proos<br />
James Prescott, Ph.D.<br />
<strong>aaps</strong> dr. rainer H<strong>of</strong>fman product Through<br />
science award<br />
2008 Gary W. Cleary, Ph.D.<br />
2009 Eugene R. Cooper, Ph.D.<br />
2010 Pr<strong>of</strong>essor Hans E. Junginger, Ph.D.<br />
2011 Francis C. Szoka, Ph.D.<br />
lipid-Based drug delivery graduate<br />
student award<br />
2008 Annalisa Mercuri<br />
Caroline Goddeeris<br />
2009 Mrs. Harisun Yaakob<br />
2010 Hazem Ali<br />
Perrine Pivette<br />
2011 Anne Tungelund Larsen<br />
<strong>2012</strong> Yan Yan Yeap<br />
Outst<strong>and</strong>ing graduate student research<br />
award in pT<br />
2001 Jukka Rantanen<br />
Sian Tiong Lim<br />
Bhas A. Dani<br />
2002 Ch<strong>and</strong>ra S. Vemavarapu<br />
Ge Jiang<br />
Vasu Venkat Sethuraman<br />
2003 Niklas Laitinen<br />
Santos B. Murty<br />
Yong Qiu<br />
2004 Stefano Giovagnoli<br />
Sinjan De<br />
Yoon Yeo<br />
2005 Loice Kikwai-Mutua<br />
Susan D’Souza<br />
Pankaj P. Dayal<br />
<strong>aaps</strong> awards HIsTOrY<br />
2006 Jerry Yong Yew Heng<br />
Preetanshu P<strong>and</strong>ey<br />
2007 Robert J. Garmise<br />
2008 Sabiruddin Mirza<br />
2009 Maike Windbergs<br />
2011 Zhe Wang<br />
<strong>2012</strong> Qi (Tony) Zhou<br />
<strong>aaps</strong> david J.w. grant research award in<br />
physical pharmacy<br />
2009 Stephen R. Byrn, Ph.D.<br />
2011 Lian Yu, Ph.D.<br />
Innovation in nanotechnology<br />
2011 Fu Chen<br />
<strong>2012</strong> Arun Kumar Upadhyay<br />
Innovation in Biotechnology awards<br />
2010 Todd Hager<br />
Hongwei Zhang<br />
Ajit Sharma<br />
Annie De Groot<br />
2011 Kaila Bennett<br />
Matthew R. Durk<br />
Diwakar Shukla<br />
Suzanna Taterewicz<br />
Chenguang Zhou<br />
<strong>2012</strong> Mark Spengler<br />
Payal Agarwal<br />
Sathy V. Balu-Iyer<br />
Shraddha Thakkar<br />
Steven Jay<br />
community service award<br />
2010 Patrick P. DeLuca, Ph.D.<br />
<strong>2012</strong> Joseph W. Polli, Ph.D.<br />
<strong>2012</strong> AAPS Annual Meeting <strong>and</strong> <strong>Exposition</strong> 33
<strong>aaps</strong> fEllOws<br />
a<br />
Moji Christianah Adeyeye, Ph.D.<br />
Akwete Lex Adjei, Ph.D.<br />
Kevin D. Altria, Ph.D.<br />
Arm<strong>and</strong>o J. Aguiar, Ph.D.<br />
Michael J. Akers, Ph.D.<br />
Kenneth S. Albert, Ph.D.<br />
S<strong>and</strong>ra R.B. Allerheiligen, Ph.D.<br />
Gordon L. Amidon, Ph.D.<br />
Gregory E. Amidon, Ph.D.<br />
Mansoor M. Amiji, Ph.D.<br />
Bradley D. Anderson, Ph.D.<br />
James B. Appino, Ph.D.<br />
Daniel W. Armstrong, Ph.D.<br />
Per Artursson, M Sci Pharm,<br />
Ph.D.<br />
Okezie I. Aruoma, Ph.D., DSc<br />
Jessie L-S. Au, Ph.D.<br />
Kenneth L. Audus, Ph.D.<br />
Larry L. Augsburger, Ph.D.<br />
Patrick Augustijns, Ph.D.<br />
Michael E. Aulton, Ph.D.<br />
Bruce Aungst, Ph.D.<br />
Kenneth E. Avis, D.Sc.<br />
James W. Ayres, Ph.D.<br />
Daniel L. Azarn<strong>of</strong>f, M.D.<br />
B<br />
You Bae, Ph.D<br />
Steven W. Baertschi, Ph.D.<br />
Marcel Bally, Ph.D.<br />
Joseph P. Balthasar, Ph.D.<br />
Ajay K. Banga, Ph.D.<br />
Gilbert S. Banker, Ph.D.<br />
Rashmi H. Barbhaiya, Ph.D.<br />
Thomas J. Bardos, Ph.D.<br />
William H. Barr, Ph.D.<br />
Jeffrey S. Barrett, Ph.D.<br />
Brian W. Barry, Ph.D.<br />
Herbert Barry, III, Ph.D.<br />
Michael G. Bartlett, Ph.D.<br />
Theodore R. Bates, Ph.D.<br />
Vijay K. Batra, Ph.D.<br />
Charan R. Behl, Ph.D.<br />
Ihor Bekersky, Ph.D.<br />
Reina Bendayan, Pharm.D.<br />
Leslie Z. Benet, Ph.D.<br />
Simon Benita, Ph.D.<br />
Terry L. Benney, Ph.D.<br />
Jean Pierre Benoit, Ph.D.<br />
Richard F. Bergstrom, Ph.D.<br />
William F. Beyer<br />
Meir Bialer, Ph.D.<br />
John A. Biles, Ph.D.<br />
Ian A. Blair, Ph.D.<br />
James Blanchard, Ph.D.<br />
34<br />
Awards Program<br />
Lawrence H. Block, Ph.D.<br />
Robert A. Blouin, Pharm.D.<br />
Nicholas S. Bodor, Ph.D.<br />
Judy P. Boehlert, Ph.D.<br />
Sanford M. Bolton, Ph.D.<br />
Peter L. Bonate, Ph.D., FCP<br />
J. Lyle Bootman, Ph.D.<br />
Ronald T. Borchardt, Ph.D.<br />
F. Douglas Boudinot, Ph.D.<br />
Ronald R. Bowsher, Ph.D<br />
Harold G. Boxenbaum, Ph.D.<br />
James C. Boylan, Ph.D.<br />
Douwe D. Breimer, Ph.D.<br />
Marcus E. Brewster, III, Ph.D.<br />
Harry G. Brittain, Ph.D.<br />
Marvin A. Brooks, Ph.D.<br />
Kim L.R. Brouwer, Ph.D.<br />
Robert W. Brueggemier, Ph.D.<br />
Graham Buckton, Ph.D.<br />
David E. Bugay, Ph.D.<br />
Hans Bundgaard<br />
Diane J. Burgess, Ph.D.<br />
Philip S. Burton, Ph.D.<br />
Louis Busse, Ph.D.<br />
Stephen R. Byrn, Ph.D.<br />
Peter R. Byron, Ph.D.<br />
c<br />
Donald E. Cadwallader, Ph.D.<br />
Henry C. Caldwell, Ph.D.<br />
Carla M. Caramella, Pharm. D.<br />
John R. Cardinal, Ph.D.<br />
David P. Carew, Ph.D.<br />
John F. Carpenter, Ph.D.<br />
C. Jelleff Carr, Ph.D.<br />
Frank I. Carroll, Ph.D.<br />
Jens T. Carstensen, Ph.D.<br />
John M. Cassady, Ph.D.<br />
Lindley A. Cates, Ph.D.<br />
Mitchell N. Cayen, Ph.D.<br />
Lester Chafetz, Ph.D.<br />
Hak-Kim Chan, Ph.D.<br />
Keith K.H. Chan, Ph.D.<br />
Kenneth K. Chan, Ph.D.<br />
William N. Charman, Ph.D.<br />
Mei-Ling Chen, Ph.D.<br />
Yie W. Chien, Ph.D.<br />
Win L. Chiou, Ph.D.<br />
Zak T. Chowhan, Ph.D.<br />
Alex<strong>and</strong>er H.C. Chun, Ph.D.<br />
Alice M. Clark, Ph.D.<br />
Gary W. Cleary, Ph.D.<br />
Jeffrey L. Clel<strong>and</strong>, Ph.D.<br />
Jordan L. Cohen, Ph.D.<br />
Wayne A. Colburn, Ph.D.<br />
Paolo Colombo, Pharm.D.<br />
Kenneth A. Connors, Ph.D.<br />
Panayiotis P. Constantinides,<br />
Ph.D.<br />
Ubaldo Conte, Pharm.D.<br />
Chyung S. Cook, Ph.D.<br />
Stephen J. Coons, Ph.D.<br />
Ge<strong>of</strong>frey A. Cordell, Ph.D.<br />
Raymond E. Counsell, Ph.D.<br />
Ronald T. Coutts, Ph.D.<br />
John C. Craig, Ph.D.<br />
Daan J.A. Crommelin, Ph.D.<br />
Peter A. Crooks, Ph.D.<br />
William G. Crouthamel, Ph.D.<br />
William Curatolo, Ph.D.<br />
Robert W. Curley, Jr., Ph.D.<br />
d<br />
David Z. D’Argenio, Ph.D.<br />
Richard N. Dalby, Ph.D.<br />
James T. Dalton, Ph.D.<br />
Meindert Danh<strong>of</strong>, Ph.D.<br />
Alekha K. Dash<br />
Stanley S. Davis, Ph.D.<br />
Patrick P. DeLuca, Ph.D.<br />
Hartmut Derendorf, Ph.D.<br />
Karl A. DeSante, Ph.D.<br />
J. Arthur de Silva, Ph.D.<br />
Melgardt M. de Villiers, Ph.D.<br />
George A. Digenis, Ph.D.<br />
Shrikant V. Dighe, Ph.D.<br />
Lewis W. Dittert, Ph.D.<br />
James T. Doluisio, Ph.D.<br />
Thomas D. Doyle, Ph.D.<br />
Jennifer B. Dressman, Ph.D.<br />
Dominique Duchêne, Ph.D.<br />
Robert N. Duvall, Ph.D.<br />
E<br />
Natalie D. Eddington, Ph.D.<br />
Gertrude B. Elion, M.S.<br />
William F. Elmquist, Ph.D.<br />
Laszlo Endrenyi, Ph.D.<br />
Ene Ette, Ph.D.<br />
William E. Evans, Pharm.D.<br />
f<br />
Stephen J. Farr, Ph.D.<br />
Reza Fassihi, Ph.D.<br />
Richard E. Faust, Ph.D.<br />
Stuart Feldman, Ph.D.<br />
Edward G. Feldmann, Ph.D.<br />
Anthony F. Fell, Ph.D.<br />
Bobbe L. Ferraiolo, Ph.D.<br />
John W.A. Findlay, Ph.D.<br />
Kenneth Finger, Ph.D.<br />
Joseph A. Fix, Ph.D.
Douglas Flanagan, Jr., Ph.D.<br />
Joseph C. Fleishaker, Ph.D<br />
Alex<strong>and</strong>er T. Florence, Ph.D.,<br />
D.Sc.<br />
Klaus G. Florey, Ph.D.<br />
Gordon L. Flynn, Ph.D.<br />
Dale E. Fonner, Ph.D.<br />
Arlington A. Forist, Ph.D.<br />
William O. Foye, Ph.D.<br />
Sylvan G. Frank, Ph.D.<br />
Ho-Leung Fung, Ph.D.<br />
g<br />
Jean P. Gagnon, Ph.D.<br />
Ping Gao, Ph.D.<br />
Andrea Gazzaniga, Ph.D.<br />
Hamid Gh<strong>and</strong>ehari, Ph.D.<br />
Kathleen M. Giacomini, Ph.D.<br />
Milo Gibaldi, Ph.D.<br />
Carol A. Gl<strong>of</strong>f, Ph.D.<br />
Morton E. Goldberg, Ph.D.<br />
Wayne R. Gombotz, Ph.D.<br />
Igor Gonda, Ph.D.<br />
Frank W. Goodhart, Ph.D.<br />
Jere E. Goyan, Ph.D.<br />
Lee T. Grady, Ph.D.<br />
G. Richard Granneman, Ph.D.<br />
David J. W. Grant, D.Phil.<br />
Thaddeus Grasela, Pharm.D,<br />
Ph.D.<br />
Gregory Gregoriadis, Ph.D.<br />
Michael J. Groves, Ph.D.<br />
Gary L. Grunewald, Ph.D.<br />
J. Keith Guillory, Ph.D.<br />
Robert Gurny, Ph.D.<br />
Richard H. Guy, Ph.D.<br />
H<br />
Jonathan Hadgraft, D.Sc.<br />
Michael J. Hageman, Ph.D.<br />
Jerome A. Halperin, M.S.<br />
Margareta Hammarlund-<br />
Udenaes, Ph.D.<br />
Robert W. Hammel, Ph.D.<br />
Manabu Hanano, Ph.D.<br />
Bruno C. Hancock, Ph.D.<br />
Justin Hanes, Ph.D.<br />
Mitsuru Hashida, Ph.D.<br />
William L. Hayton, Ph.D.<br />
Kenneth R. Heimlich, Ph.D.<br />
Jorge Heller, Ph.D.<br />
William M. Heller, Ph.D.<br />
Stanley L. Hem, Ph.D.<br />
Jack D. Henion, Ph.D.<br />
Piet Herdewijn, Ph.D.<br />
Anthony J. Hickey, Ph.D.<br />
Everett N. Hiest<strong>and</strong>, Ph.D.<br />
Takeru Higuchi, Ph.D.<br />
William I. Higuchi, Ph.D.<br />
A. Atilla Hincal, Ph.D.<br />
Gilbert J. Hite, Ph.D.<br />
Norman F.H. Ho, Ph.D.<br />
Rodney J.Y. Ho. Ph.D.<br />
Stephen W. Hoag, Ph.D.<br />
Guenther Hochhaus, Ph.D.<br />
Irwin L. Honigberg, Ph.D.<br />
Ryohei Hori, Ph.D.<br />
Zola P. Horovitz, Ph.D.<br />
Ken-ichi Hosoya, Ph.D.<br />
Richard A. Houghten, Ph.D.<br />
Oliver Hu, Ph.D.<br />
Jin-Ding Huang, Ph.D.<br />
Leaf Huang, Ph.D.<br />
Shiew-Mei Huang, Ph.D.<br />
Charles D. Hufford, Ph.D.<br />
C. Anthony Hunt, Ph.D.<br />
Ajaz Hussain, Ph.D.<br />
Anwar Hussain, Ph.D.<br />
Munir A. Hussain, Ph.D.<br />
I<br />
Lisbeth Illum, Ph.D., D.Sc.<br />
Ken-ichi Inui, Ph.D.<br />
J<br />
Fakhreddin Jamali, Ph.D.<br />
Bhaskara R. Jasti, Ph.D.<br />
Michael Jay, Ph.D.<br />
Roger Jelliffe, Ph.D.<br />
Mohammed Jemal, Ph.D.<br />
Lee Jia, Ph.D.<br />
Jan H.G. Jonkman, Ph.D.<br />
Robert S. Joslin, Ph.D.<br />
Hans E. Junginger, Ph.D.<br />
William J. Jusko, Ph.D.<br />
K<br />
Peter F. Kador<br />
James J. Kaminski, Ph.D.<br />
Isadore Kanfer, Ph.D.<br />
Stanley A. Kaplan, Ph.D.<br />
Aziz Karim, Ph.D.<br />
Howard T. Karnes, Ph.D.<br />
Martin Katz, Ph.D.<br />
Yoshiaki Kawashima, Ph.D.<br />
Ian W. Kellaway, D.Sc.<br />
Richard A. Kenley, Ph.D.<br />
Mansoor A. Khan, Ph.D.<br />
Lemont B. Kier, Ph.D.<br />
Dane O. Kildsig, Ph.D.<br />
Peter Kleinebudde, Ph.D.<br />
<strong>aaps</strong> fEllOws<br />
Chong-Kook Kim, Ph.D.<br />
Richard B. Kim, M.D.<br />
Sung W. Kim, Ph.D.<br />
A. Douglas Kinghorn, Ph.D.<br />
Arlyn W. Kinkel, Ph.D.<br />
William J. Kinnard, Ph.D.<br />
Peter T. Kissinger, Ph.D.<br />
David A. Knapp, Ph.D.<br />
Joseph E. Knapp, Ph.D.<br />
Adelbert M. Knevel, Ph.D.<br />
Edwin L. Knoechel, Ph.D<br />
Bozena (Bo) Michniak-Kohn,<br />
Ph.D.<br />
Ah-Ng Kong, Ph.D.<br />
Uday Kompella, Ph.D.<br />
Jindrich Kopecek, Ph.D.<br />
Harry B. Kostenbauder, Ph.D.<br />
Jeffrey Kotzan, Ph.D.<br />
Jorg W.R. Kreuter, Ph.D.<br />
Rajesh Krishna, Ph.D., FCP<br />
Patricia D. Kroboth, Ph.D.<br />
Deanna Kroetz, Ph.D.<br />
Roy Kuramoto, Ph.D.<br />
King Chiu Kwan, Ph.D.<br />
Glen S. Kwon, Ph.D.<br />
l<br />
Vinod Labhasetwar, Ph.D.<br />
Leon Lachman, Ph.D.<br />
Richard L. LaLonde, Pharm.D.<br />
Robert S. Langer, Sc.D.<br />
Peter R. Langguth, Ph.D.<br />
Andrew Lasslo, Ph.D.<br />
Thomas P. Layl<strong>of</strong>f, Ph.D.<br />
Jean W. Lee, Ph.D.<br />
Kang Choon Lee, Ph.D.<br />
Vincent H.L. Lee, Ph.D.<br />
Kuo-Hsiung Lee, Ph.D.<br />
Lewis J. Leeson, Ph.D.<br />
Claus-Michael Lehr, Ph.D.<br />
August P. Lemberger, Ph.D.<br />
Hans Lennernäs, Ph.D.<br />
Lawrence J. Lesko, Ph.D.<br />
Hans Leuenberger, Ph.D.<br />
Ralph S. Levi, Ph.D.<br />
Gerhard Levy, Pharm.D.<br />
Rene H. Levy, Ph.D.<br />
Xiaoling Li, Ph.D.<br />
Jiunn Huei Lin, Ph.D.<br />
Thorsteinn L<strong>of</strong>tsson, Ph.D.<br />
Ti Li Loo, D.Sc.<br />
Nicholas G. Lordi, Ph.D.<br />
Ole J. Lorenzetti, Ph.D.<br />
Donghao Robert Lu, Ph.D.<br />
Thomas M. Ludden, Ph.D.<br />
Craig Lunte, Ph.D.<br />
<strong>2012</strong> AAPS Annual Meeting <strong>and</strong> <strong>Exposition</strong> 35
<strong>aaps</strong> fEllOws<br />
Susan M. Lunte, Ph.D.<br />
Louis A. Luzzi, Ph.D.<br />
m<br />
Thomas J. Macek, Ph.D.<br />
Panos E. Macheras, Ph.D.<br />
Ram I. Mahato, Ph.D.<br />
Alex<strong>and</strong>ros Makriyannis, Ph.D.<br />
A. Waseem Malick, Ph.D.<br />
Louis Malspeis, Ph.D.<br />
Tarun K. M<strong>and</strong>al, Ph.D.<br />
Mark C. Manning, Ph.D.<br />
Arnold D. Marcus, Ph.D.<br />
Keith Marshall, Ph.D.<br />
Tobias Massa, Ph.D.<br />
Bogdan K. Matuszewski, Ph.D.<br />
Michael Mayersohn, Ph.D.<br />
William F. McGhan, Ph.D.<br />
Iain J. McGilveray, Ph.D.<br />
James W. McGinity, Ph.D.<br />
Gordon McKay, Ph.D.<br />
Jerry L. McLaughlin, Ph.D.<br />
Patrick J. McNamara, Ph.D.<br />
Thomas Medwick, Ph.D.<br />
Mehul U. Mehta, Ph.D.<br />
Bernd Meibohm, Ph.D.<br />
Srikumaran K. Melethil, Ph.D.,<br />
J.D.<br />
Hans Peter Merkle, Ph.D.<br />
Carl M. Metzler, Ph.D.<br />
Marvin C. Meyer, Ph.D.<br />
C. Russell Middaugh, Ph.D.<br />
Kamal K. Midha, D.Sc.<br />
Duane D. Miller, Ph.D.<br />
Raymond Miller, D.Sc.<br />
Tamara Minko, Ph.D.<br />
Hyman Mitchner, Ph.D.<br />
Ashim K. Mitra, Ph.D.<br />
Tom S. Miya, Ph.D.<br />
Arthur R. Mlodozeniec, Ph.D.<br />
Marilyn M. Martinez, Ph.D.<br />
Henry I. Mosberg<br />
Anthony C. M<strong>of</strong>fat, Ph.D.<br />
Joyce J. Mordenti, Ph.D.<br />
Kenneth R. Morris, Ph.D.<br />
Marilyn E. Morris, Ph.D.<br />
Daniel Mufson, Ph.D.<br />
Pasupati Mukerjee, Ph.D.<br />
Russell J. Mumper, Ph.D.<br />
Eric J. Munson, Ph.D.<br />
Ram B. Murty, Ph.D.<br />
36<br />
Awards Program<br />
n<br />
Tsuneji Nagai, Ph.D.<br />
Steven L. Nail, Ph.D.<br />
Masahiro Nakano, Ph.D.<br />
Moheb M. Nasr, Ph.D.<br />
Kenneth G. Nelson, Ph.D.<br />
Wendel L. Nelson, Ph.D.<br />
John L. Neumeyer, Ph.D.<br />
Tue H. Nguyen, Ph.D.<br />
David E. Nichols, Ph.D.<br />
G. Joseph Norwood, Ph.D.<br />
Robert E. Notari, Ph.D.<br />
O<br />
Derek T. O’Hagan, Ph.D.<br />
Bernard A. Olsen, Ph.D.<br />
Hayat Onyuksel, Ph.D.<br />
Masaki Otagiri, Ph.D.<br />
p<br />
Kim-Ching (S<strong>and</strong>y) Pang, Ph.D.<br />
Gerald J. Papariello, Ph.D.<br />
Kinam Park, Ph.D.<br />
Eugene L. Parrott, Ph.D.<br />
Dev S. Pathak, D.B.A.<br />
Thomas F. Patton, Ph.D.<br />
Rodney Pearlman, Ph.D.<br />
Carl C. Peck, M.D.<br />
Garnet E. Peck, Ph.D.<br />
Nicholas A. Peppas, Sc.D.<br />
Bengt-Arne Persson, Ph.D.<br />
Claude Piantadosi, Ph.D.<br />
Henry J. Pieniaszek, Jr., Ph.D.<br />
Michael J. Pikal, Ph.D.<br />
Ian H. Pitman, Ph.D.<br />
Fridrun Podczeck, Dr. sc. nat.<br />
habil.<br />
Gary M. Pollack, Ph.D.<br />
James E. Polli, Ph.D.<br />
Joseph W. Polli, Ph.D<br />
John W. Poole, Ph.D.<br />
Emil Pop, Ph.D.<br />
David G. Pope, Ph.D.<br />
Philip S. Portoghese, Ph.D.<br />
Russell O. Potts, Ph.D.<br />
Boyd J. Poulsen, Ph.D.<br />
Colin W. Pouton, Ph.D.<br />
J. Robert Powell, Ph.D.<br />
Michael F. Powell, Ph.D.<br />
Vadlamani K. Prasad, Ph.D.<br />
Thomayant Prueksaritanont,<br />
Ph.D.<br />
William P. Purcell, Ph.D.<br />
Q<br />
Yihong Qiu, Ph.D.<br />
r<br />
Galen W. Radebaugh, Ph.D.<br />
Yueh-Erh Rahman, M.D.<br />
Theodore R<strong>and</strong>olph, Ph.D.<br />
Rao S. Rapaka, Ph.D.<br />
Louis J. Ravin, Ph.D.<br />
Indra K. Reddy, Ph.D.<br />
Robert A. Reed, Ph.D.<br />
Gurvinder Singh Rekhi, Ph.D.<br />
Jean Paul Remon, Ph.D.<br />
Michael A. Repka, Ph.D.<br />
A.J. Repta, Ph.D.<br />
Richard H. Reuning, Ph.D.<br />
Christopher T. Rhodes, Ph.D.<br />
Kenner C. Rice, Ph.D.<br />
Christopher M. Riley, Ph.D.<br />
Edward G. Rippie, Ph.D.<br />
Wolfgang A. Ritschel, M.D.,<br />
Ph.D.<br />
Joseph R. Robinson, Ph.D.<br />
Christopher A. Rodowskas<br />
A. David Rodrigues, Ph.D.<br />
Yongyut Rojanasakul, Ph.D<br />
Alain Roll<strong>and</strong>, Ph.D.<br />
Theodore J. Roseman, Ph.D.<br />
Amy Rosenberg, M.D.<br />
Carlo Rossi, Pharm.D.<br />
Malcolm Rowl<strong>and</strong>, Ph.D.<br />
Frans G.M. Russel, Ph.D.<br />
Emanuel J. Russo, Ph.D.<br />
Charles O. Rutledge, Ph.D.<br />
J. Howard Rytting, Ph.D.<br />
s<br />
M<strong>and</strong>ip S. Sachdeva, Ph.D.<br />
Wolfgang Sadée, Ph.D.<br />
A. Adel Sakr, Ph.D.<br />
Lynda M. S<strong>and</strong>ers, Ph.D.<br />
Ronald J. Sawchuk, Ph.D.<br />
Jerome J. Schentag, Pharm.D.<br />
Jean-Michel G. Scherrmann,<br />
Pharm.D., Ph.D.<br />
Paul L. Schiff, Jr., Ph.D.<br />
Peter Wilhelm Schiller, Ph.D.<br />
George Schneller, Ph.D.<br />
Christian Schöneich, Ph.D.<br />
Joseph B. Schwartz, Ph.D.<br />
Michael A. Schwartz, Ph.D.<br />
John J. Sciarra, Ph.D.<br />
James A. Seitz, Ph.D.<br />
Bernard Z. Senkowski, Ph.D.
Cosette J. Serabjit-Singh, Ph.D.<br />
Abu Serajuddin, Ph.D.<br />
Hitoshi Sezaki, Ph.D.<br />
Ashok C. Shah, Ph.D.<br />
Navnit H. Shah, Ph.D.<br />
Vinod P. Shah, Ph.D.<br />
Evgenyi Shalaev, Ph.D.<br />
Jane E. Shaw, Ph.D.<br />
Eli Shefter, Ph.D.<br />
Eric B. Sheinin, Ph.D.<br />
John W. Shell, Ph.D.<br />
Danny D. Shen, Ph.D.<br />
Wei-Chiang Shen, Ph.D.<br />
Chang-Koo Shim, Ph.D.<br />
Steven J. Shire, Ph.D.<br />
Teruna Siahaan, Ph.D.<br />
Ronald A. Siegel, Sc.D.<br />
Jeffrey A. Silverman, Ph.D.<br />
Anthony P. Simonelli, Ph.D.<br />
Jagdish Singh, Ph.D.<br />
Manmohan Singh, Ph.D.<br />
Sampat M. Singhvi, Ph.D.<br />
Patrick J. Sinko, Ph.D.<br />
Anthony A. Sinkula, Ph.D.<br />
John A. Sjögren, Ph.D.<br />
Jerome P. Skelly, Ph.D.<br />
John T. Slattery, Ph.D.<br />
David E. Smith, Ph.D.<br />
Edward Smith, Ph.D.<br />
Mickey C. Smith, Ph.D.<br />
Philip L. Smith, Ph.D.<br />
R<strong>and</strong>all B. Smith, Ph.D.<br />
Quentin Smith, Ph.D.<br />
Robert V. Smith, Ph.D.<br />
Theodore D. Sokoloski, Ph.D.<br />
Albert H. Soloway, Ph.D.<br />
Marilyn K. Speedie, Ph.D.<br />
John Staniforth, Ph.D.<br />
Salomon A. Stavchansky, Ph.D.<br />
Valentino J. Stella, Ph.D.<br />
Larry A. Sternson, Ph.D.<br />
James T. Stewart, Ph.D.<br />
Clinton Fields Stewart,<br />
Pharm.D.<br />
Audra Stinchcomb, Ph.D.<br />
John F. Stobaugh, Ph.D.<br />
Robert M. Straubinger, Ph.D.<br />
Heinz B. Sucker, Ph.D.<br />
Yuichi Sugiyama, Ph.D.<br />
Raj Suryanaryanan, Ph.D.<br />
Steven C. Sutton, Ph.D.<br />
Hiroshi Suzuki, Ph.D.<br />
Craig K. Svensson, Ph.D.<br />
Peter W. Swaan, Ph.D.<br />
Steven J. Swanson, Ph.D.<br />
James Swarbrick, Ph.D.<br />
Joseph V. Swintosky, Ph.D.<br />
Francis C. Szoka, Jr., Ph.D.<br />
T<br />
Yoshinobu Takakura, Ph.D.<br />
Vijay K. Tamarra, Ph.D.<br />
Diane D-S. Tang-Liu, Ph.D.<br />
Rashad Tawashi, Ph.D.<br />
Lynne S. Taylor, Ph.D.<br />
David H. Tedeschi, Ph.D.<br />
Tetsuya Terasaki, Ph.D.<br />
Bernard J. Testa, Ph.D.<br />
Dhiren R. Thakker, Ph.D.<br />
Felix Theeuwes, Ph.D.<br />
Gary A. Thompson, Ph.D.<br />
Kenneth E. Thummel, Ph.D.<br />
Alice E. Till, Ph.D.<br />
William J. Tillman, Ph.D.<br />
James E. Tingstad, Ph.D.<br />
Eric Tomlinson, Ph.D.<br />
Elizabeth M. Topp, Ph.D.<br />
Vladimir P. Torchilin, Ph.D.,<br />
D.Sc.<br />
Thomas N. Tozer, Ph.D.<br />
Timothy S. Tracy, Ph.D.<br />
Francis L.S. Tse, Ph.D.<br />
Akira Tsuji, Ph.D.<br />
Varro E. Tyler, Ph.D.<br />
u<br />
Kaneto Uekama, Ph.D.<br />
Jashvant D. Unadkat, Ph.D.<br />
Sathyanarayana M.<br />
Upadrashta, Ph.D.<br />
John Urquhart, M.D.<br />
Arto O. Urtti, Ph.D.<br />
V<br />
Elizabeth B. Vadas, Ph.D.<br />
Glen A. Van Buskirk, Ph.D.<br />
Peter Veng-Pedersen, Ph.D.<br />
Jurgen Venitz, Ph.D.<br />
Raman Venkataramanan, Ph.D.<br />
S. Jorgen Vessman, Pharm.D.,<br />
Ph.D.<br />
Paolo Vicini, Ph.D.<br />
C. T. Viswanathan, Ph.D.<br />
w<br />
John A. Wagner, M.D., Ph.D<br />
John G. Wagner, Ph.D.<br />
Irving W. Wainer, Ph.D.<br />
Walter D. Walkling, Ph.D.<br />
<strong>aaps</strong> fEllOws<br />
Jesse W. Wallace<br />
Y. John Wang, Ph.D.<br />
Kishor M. Wasan, Ph.D.<br />
Kenneth Waterman, Ph.D.<br />
Lawrence C. Weaver, Ph.D.<br />
Jeffry G. Weers, Ph.D.<br />
Norman D. Weiner, Ph.D.<br />
Peter G. Welling, Ph.D.<br />
Albert I. Wertheimer, Ph.D.<br />
Joseph Wiederholt, Ph.D.<br />
M. Guillaume Wientjes, Ph.D.<br />
Grant R. Wilkinson, Ph.D.<br />
Roger L. Williams, M.D.<br />
Robert O. Williams, Ph.D.<br />
Robert J. Wills, Ph.D.<br />
Donald T. Witiak, Ph.D.<br />
Manfred E. Wolff, Ph.D.<br />
Hal N. Wolk<strong>of</strong>f, Ph.D.<br />
John H. Wood, Ph.D.<br />
Paul E. Wray, Ph.D.<br />
George Wright, Ph.D.<br />
Dale E. Wurster, Ph.D.<br />
Dale Eric Wurster, Ph.D.<br />
Y<br />
Avraham Yacobi, Ph.D.<br />
Gerald J. Yakatan, Ph.D.<br />
Samuel H. Yalkowsky, Ph.D.<br />
Shinji Yamashita, Ph.D.<br />
Victor C. Yang, Ph.D.<br />
Peter York, Ph.D.<br />
Sumie Yoshioka, Ph.D.<br />
Lawrence X. Yu, Ph.D.<br />
Lian Yu, Ph.D.<br />
Su Il Yum, Ph.D.<br />
Z<br />
Alej<strong>and</strong>ro A. Zaffaroni, Ph.D.<br />
Gaylen M. Zentner, Ph.D.<br />
Ge<strong>of</strong>f G.Z. Zhang, Ph.D.<br />
Chang-Guo Zhan, Ph.D.<br />
Cheryl L. Zimmerman, Ph.D.<br />
George Zografi, Ph.D.<br />
<strong>2012</strong> AAPS Annual Meeting <strong>and</strong> <strong>Exposition</strong> 37
38<br />
Awards Program