PeloBiotech

www.pelobiotech.com
Cells & Tissues
iPS Cells
Induced Pluripotent Stem Cells (iPSCs) have revolutionized the field of regenerative medicine and scientific research by
offering a versatile platform for studying and harnessing the potential of stem cells. These remarkable cells, pioneered
by Dr. Shinya Yamanaka, are capable of differentiating into a wide range of cell types, mirroring the attributes of
embryonic stem cells. We offer a wide range of reprogramming tools, recombinant proteins and small molecules for this
application. Recombinant proteins, synthetic transcription factors, enhance targeted reprogramming, while small
molecules, such as valproic acid, optimize efficiency and maintain pluripotency. Additionally, the choice of an appropriate
coating for culture vessels such as recombinant Laminin is crucial in supporting iPSC attachment, proliferation, and
differentiation.
Every cell type will have a variant of integrin and thereby you will require a specific laminin for each cell type, we
recommend you check out our ECM solutions i-Matrix 211, 411, 511. This integrated approach, including proper
coating considerations, streamlines iPSC generation, addressing safety concerns and making them a valuable resource
for scientific and regenerative applications.
• Ready-to-use iPSCs crafted from different techniques such as footprint-free StemRNA 3rd Gen Reprogramming
Technology, Retrovirus & Sendai virus.
• No need for specialized reprogramming expertise.
• Available from both males and females, complete with donor clinical status.
• Sourced from skin fibroblasts and blood endothelial progenitor cells.
We would like to point out to you as an interested party in genetically modified cells (e.g. iPS cells, GFP/RFP
tagged cells) that you have a corresponding authorized genetic engineering facility for the storage, use and
disposal in which this organism is processed.
iPS cells and/or GFP/RFP expressing cells produced by infection using viruses are deemed potential hazards
and are graded Biosafety Level 1.
Restrictions are placed on the distribution of Biosafety Level 2 cells. Cells infected with human pathogenic
viruses, or known to release human pathogenic viruses may be distributed only to customers who provide
evidence that they have the necessary authorization to work with pathogens. In Germany, a permit according
to §44 Infektionsschutzgesetz (IfSG) must be provided. For exceptions, see §45 IfSG. Customers from outside
Germany must show a valid permit provided by their competent authorities. PELOBiotech GmbH reserves the
right to decline the shipment of Biosafety Level 2 cells.
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