PeloBiotech
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www.pelobiotech.com<br />
Proteins<br />
Proteins, essential building blocks of life, are pivotal in diverse scientific applications. Their structural intricacies, unveiled<br />
through techniques like X-ray crystallography, inform drug design and targeted therapies. Serving as enzymatic catalysts,<br />
proteins drive biochemical reactions crucial for biotechnology, medicine, and environmental science. In cell signaling,<br />
proteins regulate physiological responses and are targets for therapeutic interventions, especially in diseases like cancer.<br />
Biotechnological advancements leverage proteins for synthesizing therapeutic agents and engineering novel functions in<br />
synthetic biology. Additionally, proteins are indispensable in diagnostics, with biomarkers aiding disease detection and<br />
monitoring. In essence, proteins are the linchpin of scientific progress, contributing to our understanding of life and<br />
propelling innovations across various disciplines.<br />
Recombinant Proteins<br />
Our extensive offering includes a diverse range of recombinant proteins targeting CD73, GPC3, Siglec-15, FGL1,<br />
and more. Available in formats like Fc-fusion, 6His-tag, and Fc-tag, these proteins are sourced from various<br />
entities—human, mice, rat, rhesus, rabbit, and even viruses like SARS-CoV-2. Biotinylated versions add flexibility<br />
to your research. Essential proteins like immunoglobulins and VEGFR further empower investigations across<br />
scientific domains.<br />
Human Proteins<br />
Recombinant human proteins play vital roles in medicine and biotechnology. Insulin manages diabetes, PDGFs aid<br />
wound healing, and growth factors like SCF, bFGF, and EGF contribute to cell proliferation and tissue<br />
regeneration. TGF-beta 1 regulates growth and differentiation, ensuring high-quality standards through cGMP.<br />
Proteins like GM-CSF stimulate white blood cell production, and cGMP-produced EPO is vital for treating anemia.<br />
Enzymes<br />
Anti-lysozyme, anti-cystatin C, and anti-gelsolin serve as valuable tools in research and diagnostics, detecting and<br />
quantifying specific proteins. Amylase detection kits (amY-Kit) assess amylase activity for insights into pancreatic<br />
and salivary gland function. The animal-free nature of these proteins ensures ethical production methods, setting<br />
them apart from cGMP-produced counterparts.<br />
Growth Factors<br />
Animal-free growth factors play pivotal roles in cell growth, proliferation, and differentiation. PDGFs aid wound<br />
healing, FLT-3L stimulates immune cell production, and M-CSF regulates macrophage development. Oncostatin<br />
M and TGF beta 3 find applications in inflammation, tissue regeneration, and embryonic development. VEGFs are<br />
key players in angiogenesis, RANK Ligand is essential for bone remodeling, and beta NGF is involved in the nervous<br />
system. Animal-free versions ensure ethical and controlled applications.<br />
Chemokines<br />
Among the diverse offerings, chemokines play a crucial role in immune responses and inflammation. Chemokines<br />
guide the movement of immune cells to specific sites in the body. Examples include CCL2 (Monocyte<br />
Chemoattractant Protein-1) and CXCL8 (Interleukin-8), which attract monocytes and neutrophils, respectively.<br />
These chemokines are valuable tools in research, particularly in studying diseases involving immune cell<br />
recruitment. Their application extends to diagnostics, aiding in the detection and quantification of specific proteins.<br />
The ethical and controlled production of these chemokines distinguishes them from cGMP-produced counterparts.<br />
Cytokines<br />
Cytokines have diverse applications in immunotherapy, cancer treatment, and research. ILs modulate immune<br />
responses, with IL-2 used in cancer immunotherapy. TNF-alpha is employed in cancer treatment and autoimmune<br />
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