PeloBiotech

www.pelobiotech.com
Applications:
• PhenoDrive-Y induces the formation of human bone marrow stromal cells (MSC) spheroids and angiogenic
sprouting of endothelial cells.
• PhenoDrive-I promotes the differentiation of induced pluripotent stem cells (iPSC) in brain cortical neuron
networks and facilitates axonal growth in various neural cells.
• PhenoDrive-R is suitable for most tissue cell phenotypes and supports the adhesion of
monocytes/macrophages, mimicking their location in connective tissues.
• PhenoDrive-PS induces osteoblast differentiation and is effective for MSC differentiation into osteoblasts.
• PhenoDrive-U is versatile for most tissue cells and ensures adhesion through weak interactions with the cell
glycocalyx, facilitating spheroid formation.
• PhenoDrive-Q continuously consumes oxygen, creating localized low oxygen tension, and is recommended for
cancer cell micro-masses and chondrocytes induction.
User-Friendly and Flexible:
• Provided as lyophilized powder.
• Easily reconstituted in ethanol or aqueous media.
• Compatible with various plasticware and 3D scaffolds.
• Gamma- and UV-stable, maintaining optical and physicochemical properties.
3-in-1 Plate
Introducing the 3-in-1 Plate, a revolutionary hydrogel insert
seamlessly designed to fit within each well of a standard sixwell
plate. This innovative insert offers a comprehensive platform for spheroid/organoid
formation, extracellular matrix integration, and drug testing, all in one. The hydrogel
comes pre-inserted within each well, with each insert featuring four quadrants capable of
accommodating six spheroids/organoids per quadrant, enabling a total of 144 formations
per plate. Notably, the quadrants are independent, allowing researchers to run four
different experimental conditions concurrently on a single insert. The hydrogel itself is
non-cell-adhesive, offering numerous benefits and ensuring disturbance-free experimentation. The 3-in-1 Plate
revolutionizes spheroid/organoid culture, drug testing, and downstream analysis, all while maintaining optimal
experimental consistency and reducing cell requirements. Explore the advantages of this groundbreaking platform below:
• Integrated Platform: Cultivate, embed in an extracellular matrix, test drugs, and perform downstream analysis
without the need to remove spheroids/organoids from the platform.
• Consistent Results: Low spheroid/organoid size variance enhances experimental consistency.
• Isolated Conditions: One spheroid/organoid per microwell eliminates the possibility of inter-model crosstalk,
ensuring accurate and isolated experimental conditions.
• Disturbance-Free Media Changes: Safely change media without
the risk of aspirating or disrupting spheroids.
• Reduced Cell Requirements: Low cell requirements reduce the
necessity to passage cells before experimentation.
• Compatibility with Imaging Techniques: The platform
compatible with in situ immunostaining and imaging.
• Comprehensive IHC Analysis: Researchers can perform all steps
of in situ IHC analysis without removing spheroids from the platform, from dehydration to wax embedding
and slicing.
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