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PeloBiotech

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www.pelobiotech.com<br />

HydroSeev<br />

HydroSeev is a hydrogel supplement to overcome disadvantages of hydrogels like low stability and mechanical properties.<br />

HydroSeev is a biopolymer providing mechanical support to hydrogels like Alginate, Matrigel ® or Silica Extragel Matrix.<br />

Just adding 0,02% HydroSeev will improve viscosity, promotes a better porosity and mechanical stability. The distribution<br />

of cells within hydrogels is improved as well.<br />

Addition of 0.02% HydroSeev to cell cultures improves: A. Cell distribution in alginate (3.5%) hydrogel (green - HydroSeev, blue- cell<br />

clusters). B. Hydrogel viscosity is improved upon addition of HydroSeev. C. Mechanical properties of cell-seeded alginate hydrogel are<br />

significantly improved when HydroSeev is added (left). Stress-strain curve of compressed cell-seeded alginatehydrogel (right). Pic:<br />

SEEVIX<br />

Phenodrive<br />

Phenodrive, introduced by our partner Tissue Click, represents a revolutionary class of specialized substrates meticulously<br />

designed for organotypic tissue cultures and organoids. This synthetic biomaterial serves as a versatile platform for<br />

culturing and testing various cell phenotypes, manifesting as spheroids and co-culture models. Its design closely mimics<br />

tissue microenvironments, encompassing stem cell niches, epithelia, cancer masses, hepatocyte spheroids, and hypoxic<br />

conditions. Phenodrive's biomimetics seamlessly adapt to both 2D and 3D culture conditions, effortlessly accommodating<br />

commonly used plasticware.<br />

Key Features:<br />

• Composed of hyperbranched molecules presenting a range of bioligands.<br />

• Ordered presentation of cell-binding molecules at high density.<br />

• Suitable for 2D and 3D culture conditions.<br />

Cell Phenotypes:<br />

Individual ECMs are tailored for various cell phenotypes, including Stem Cells, Endothelial, Neural, Epithelial, Osteoblasts,<br />

Chondrocytes, Hepatocytes, Fibroblasts, Keratinocytes, Pancreatic beta cells, and Cancer cells. Different formulations<br />

cater to specific cell types.<br />

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