PeloBiotech
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www.pelobiotech.com<br />
HydroSeev<br />
HydroSeev is a hydrogel supplement to overcome disadvantages of hydrogels like low stability and mechanical properties.<br />
HydroSeev is a biopolymer providing mechanical support to hydrogels like Alginate, Matrigel ® or Silica Extragel Matrix.<br />
Just adding 0,02% HydroSeev will improve viscosity, promotes a better porosity and mechanical stability. The distribution<br />
of cells within hydrogels is improved as well.<br />
Addition of 0.02% HydroSeev to cell cultures improves: A. Cell distribution in alginate (3.5%) hydrogel (green - HydroSeev, blue- cell<br />
clusters). B. Hydrogel viscosity is improved upon addition of HydroSeev. C. Mechanical properties of cell-seeded alginate hydrogel are<br />
significantly improved when HydroSeev is added (left). Stress-strain curve of compressed cell-seeded alginatehydrogel (right). Pic:<br />
SEEVIX<br />
Phenodrive<br />
Phenodrive, introduced by our partner Tissue Click, represents a revolutionary class of specialized substrates meticulously<br />
designed for organotypic tissue cultures and organoids. This synthetic biomaterial serves as a versatile platform for<br />
culturing and testing various cell phenotypes, manifesting as spheroids and co-culture models. Its design closely mimics<br />
tissue microenvironments, encompassing stem cell niches, epithelia, cancer masses, hepatocyte spheroids, and hypoxic<br />
conditions. Phenodrive's biomimetics seamlessly adapt to both 2D and 3D culture conditions, effortlessly accommodating<br />
commonly used plasticware.<br />
Key Features:<br />
• Composed of hyperbranched molecules presenting a range of bioligands.<br />
• Ordered presentation of cell-binding molecules at high density.<br />
• Suitable for 2D and 3D culture conditions.<br />
Cell Phenotypes:<br />
Individual ECMs are tailored for various cell phenotypes, including Stem Cells, Endothelial, Neural, Epithelial, Osteoblasts,<br />
Chondrocytes, Hepatocytes, Fibroblasts, Keratinocytes, Pancreatic beta cells, and Cancer cells. Different formulations<br />
cater to specific cell types.<br />
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