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PeloBiotech

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www.pelobiotech.com<br />

3D Hydrogel-based<br />

Organotypic Hydrogels - TissueSpec® Matrix Hydrogel<br />

TissueSpec ® Hydrogel Kits are acellular matrix products derived from a<br />

variety of porcine organs and tissues. Versatile<br />

in format, hydrogel matrix kits offer the matrix components present in<br />

natural tissues and recreates a physiological substrate for 3D cell culture.<br />

TissueSpec® Hydrogel Kits have been shown to enhance cell attachment,<br />

growth, and function in stem cell research. These<br />

kits are designed for easy application in cell culture and provide structural,<br />

mechanical, and compositional cues of the native tissue<br />

microenvironment.<br />

TissueSpec ® Liver Hydrogel contains liver specific matrix components.<br />

• Compatible with standard cell culture programs<br />

• Lot to lot Consistency<br />

• Easy to Use<br />

Hydrogel can be applied as a thin gel. Liver cells migrate into<br />

hydrogel, enabling migration and invasion assays.<br />

Low-density lipoprotein uptake<br />

TissueSpec® Liver Hydrogel. liver cells show higher expression of LDL<br />

receptor and secretion of fibrinogen. pics: Xylyx Bio<br />

For optimal results: Combine Microvascular Endothelial Cell Growth Medium Kit enhanced (PB-MH 100-4099) with<br />

PELOBiotech-Cells. Ask for our human and animal cell list.<br />

Natural Hydrogels – Collagen & Fibronectin<br />

MatriMix<br />

The first MatriMix product, MatriMix (511), is composed of fibrillar collagen, recombinant human laminin-511 E8<br />

fragment, and hyaluronic acid. The types of collagen, isoforms of laminin, and the concentration of each component have<br />

been customized to provide the optimal extracellular environment for your target cells. Gelation takes advantage of<br />

collagen's ability to form fibers at a physiological temperature and solvent environment.<br />

52<br />

Figure 1 Cells derived from<br />

tissues during mouse<br />

development were cultured<br />

in 3D using MatriMix. Cell<br />

organization occurred by day<br />

7 of culture.

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