PeloBiotech
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www.pelobiotech.com<br />
Starvation<br />
Starvation medium, devoid of serum nutrients or growth factors, is used to synchronize the cell cycle or study cellular<br />
responses under nutrient-deprived conditions. RPMI 1640 Medium without serum serves as an example, providing<br />
controlled conditions for experiments requiring a synchronized cell population.<br />
Customized media<br />
We offer customized media with or without various supplements as the use of media without phenol red, glutamine, and<br />
other supplements has been a subject of interest in various research areas. Phenol red, commonly used as a pH indicator in<br />
tissue culture media, has been found to have significant estrogenic activity, raising concerns about its potential impact on<br />
the study of estrogen-responsive cells in culture. Glutamine, an amino acid, has been studied for its anti-fatigue effects in<br />
sports nutrition, with observations on its impact on plasma glutamine levels and time to exhaustion. The role of common<br />
cell culture media supplements, including phenol red, penicillin/streptomycin, L-glutamine, and β-mercaptoethanol, has<br />
been investigated in the formation of gold nanoparticle protein corona, aggregation state, and cellular uptake, shedding<br />
light on their influence on cellular interactions. The impact of tissue culture components, including phenol red, on energy<br />
loss in cell culture equipment has been studied, validating the use of phenol-red containing media as physiologically relevant<br />
when examining light-culture system interactions.<br />
Glutamine supplementation has been the subject of clinical trials and systematic reviews to evaluate its effects on<br />
cardiometabolic risk factors and inflammatory markers, contributing to the understanding of its potential role in modulating<br />
plasma glutamine concentration and inflammation. Moreover, the formation of low-density plasma in aqueous biological<br />
media without phenol red supplementation has been achieved, demonstrating the influence of media components on<br />
plasma formation. Thereby for your special needs we can offer customized media if you can think it we can make it.<br />
& Cold management<br />
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