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PeloBiotech

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www.pelobiotech.com<br />

Tissues<br />

We provide researchers with high quality human tissue samples sourced from various organs. These samples exhibit<br />

high RIN scores and are available from both healthy and diseased donors. Our extensive donor information includes<br />

details such as gender, age, ethnicity, BMI, cause of death, smoking and alcohol use history, HLA typing, and past<br />

medical records.<br />

Applications<br />

Spinal sections encompass a wide range of uses, including target profiling and engagement, spatial omics analysis,<br />

functional and structural interrogation, and their role in CNS drug discovery. Additionally, they are crucial in studying<br />

neurotoxicity and neuropathy, contributing significantly to the field of neurological research.<br />

Lung sections find application in studying cytokine release, gene expression, immune cell activation, transcriptomics, and<br />

proteomics. They are instrumental in investigating airway contraction and relaxation dynamics and the regulation of blood<br />

vessel constriction and dilation, making them vital tools for respiratory research.<br />

Heart sections play a pivotal role in target expression and localization studies, spatial omics analysis, functional assays,<br />

and action potential measurements. They are essential for understanding proarrhythmia, inotropic effects, force<br />

production, vascular tone regulation, and the assessment of chamber-specific efficacy and safety, thereby contributing to<br />

cardiovascular research and drug development.<br />

Dorsal root ganglia sections are employed in target profiling and engagement, as well as functional and structural<br />

interrogation. They play a crucial role in pain and itch drug discovery, as well as research related to neurotoxicity and<br />

neuropathy, enhancing our understanding of sensory and peripheral nervous systems.<br />

Brain sections offer valuable insights into target expression and localization, spatial omics, immunocytochemistry, and<br />

the application of RNAscope technology. They are indispensable in neuroscientific research, providing a foundation for<br />

understanding neural processes and cellular interactions in the brain.<br />

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