PeloBiotech

www.pelobiotech.com
Additionally, endothelial cells have been implicated in the development of intestinal fibrosis and have been shown to
contribute to the pathogenesis of necrotizing enterocolitis. Epithelial cells have been investigated for their involvement
in intestinal inflammation, barrier function, and the response to radiation-induced injury. Studies have shown that
epithelial cells are involved in radiation-induced intestinal injury, with the epithelial cells being the most important target
of radiation damage, which may subsequently induce apoptosis in endothelial cells.
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Urethra
We provide primarily epithelial cells from the urethra,
and the RNA of these cells as well. The primarily
epithelial cells from the urethra have been studied for
their role in the development, function, and
regeneration of the urethra. These cells have been
shown to express androgen receptors, and their
differentiation has been observed in the urothelium
of the prostatic urethra and prostatic luminal
epithelial cells. Single-cell RNA sequencing has been
used to obtain a complete transcriptomic profile of all
epithelial cells in the mouse prostate and urethra to
identify cellular subtypes. The expression of
cytokeratin 7, uroplakin, and FoxA1 has been
observed in the urethral plate and developing urethra
of the penile glans, indicating the presence of
proteins of epithelial cells of endodermal origin.
The urethral luminal epithelia have been identified as castration-insensitive cells of the proximal prostate, and they have
been shown to undergo a prostate luminal to club cell transition in benign prostatic hyperplasia. Additionally, the urethral
epithelial cells have been used in the fabrication of tissue-engineered bionic urethras using cell sheet technology for fullthickness
urethral reconstruction. These studies collectively demonstrate the diverse applications of primarily epithelial
cells from the urethra in understanding urethral development, function, and regeneration.
Stomach
We extract epithelial cells, smooth muscle cells, and primary stomach cells from the stomach, sourcing them from
various species. Epithelial cells from the stomach have been investigated for their role in the development and function
of the stomach. Studies have shown that the completeness of the stomach development is marked by the appearance of
non-specific esterase activity in the stomach epithelial cells. Additionally, the adherence of lactic acid bacteria to the
columnar epithelial cells of the stomach has been studied, providing insights into the microbial colonization of the
stomach. Smooth muscle cells from the stomach have been studied for their involvement in gastric motility and the
pathogenesis of stomach diseases. These cells play a crucial role in the regulation of gastric motility and peristalsis,
contributing to the digestive function of the stomach.
Umbilical cord
We isolate a range of cell types, including human umbilical vein endothelial cells,
various shRNA-stable transfected HUVECs, HUVECs with GFP tags in the
mitochondria and plasma membrane, conditionally immortalized umbilical cord
MSCs, HUVECs from arteries and veins, and whole cell RNAs.
The uses of human umbilical vein endothelial cells (HUVECs) are diverse and
significant in various research areas. HUVECs have been utilized in studying
cytoprotective pathways, modeling atherosclerosis, investigating protective effects
against injury, analyzing angiogenesis and lymphangiogenesis, and exploring
autophagy induction. HUVECs have been employed in the study of lactateinduced
pathways in endothelial cells, as well as in investigating the effects of
activated protein C on endoplasmic reticulum stress and apoptosis.
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