PeloBiotech

www.pelobiotech.com
IPSCs have been investigated for their use in dentistry, immunotherapy, and as a tool for personalized autologous body
organ transplant, showcasing their expanding role in different medical fields (Hynes et al., 2015; Jiang et al., 2013; Palomo
et al., 2014). Moreover, iPSCs have been utilized for modeling inherited cardiomyopathies, bone regeneration, and as a
platform for drug screening and disease modeling, further emphasizing their broad applications in medicine (Karakikes et
al., 2014; Tang et al., 2014; Hwang et al., 2021). The potential of iPSCs in regenerative medicine has also been recognized
through the development of liver buds and clinical-grade neural stem cells, highlighting the ongoing efforts to harness
iPSCs for clinical applicability (Sekine et al., 2020; Cai et al., 2021).
We offer:
• Around 10,000 human disease models for preclinical drug development
• Diverse models, including spheroid and organoid models, physiological barrier models, and more.
• An extensive selection of iPSC derivative cell types, from pericytes to cardiomyocytes, for a wide range of
research applications
Below is a summary of the cell types we provide. Please note that this list is not exhaustive. To explore our complete cell
offerings, we encourage you to request our detailed cell list or visit pelobiotech.com for additional information.
iPSC-Derived Cardiomyocytes (Heart):
Cardiotoxicity screening for drug development.
Studying heart diseases and genetic disorders.
Regenerative medicine for cardiac tissue repair.
iPSC-Derived Hepatocytes (Liver):
Drug metabolism and toxicity testing.
Modeling liver diseases and viral infections.
Development of bioartificial liver devices.
iPSC-Derived Hepatic Stellate Cells and Kupffer Cells (Liver):
Investigating liver fibrosis and cirrhosis.
Testing anti-fibrotic drugs for liver disease treatment.
Understanding hepatic stellate cell biology.
iPSC-Derived Neurons (Brain):
Modeling neurodegenerative diseases like Alzheimer's
Drug discovery and testing for neurological disorders.
Studying neural development and function.
iPSC-Derived Keratinocytes (Skin):
Skin disease modeling, such as epidermolysis bullosa.
Wound healing and tissue regeneration studies.
Drug testing for dermatological conditions.
iPSC-Derived Endothelial Cells:
Investigating cardiovascular diseases and vascular disorders.
Testing anti-angiogenic drugs for cancer therapy.
Vascular tissue engineering and regenerative medicine.
iPSC-Derived Kidney Cells:
Investigating renal diseases and disorders.
Testing personalized medicaments for kidney health.
Studying drug responses specific to kidney function
iPSC-Derived Hematopoietic Stem Cells (HSCs):
Studying blood disorders like anemia and leukemia.
Personalized therapies for hematological disorders
Drug screening for hematological conditions.
iPSC-Derived Hematopoietic Stem Cells (HSCs):
Studying blood disorders like anemia and leukemia.
Developing personalized cell therapies
for blood-related diseases.
Drug screening for hematological conditions.
iPSC-Derived Immune Cells:
Modeling autoimmune diseases and immunodeficiencies.
Developing immunotherapies and vaccines.
Screening for immunomodulatory drugs and treatments.
10