33 Special Types of Invasive Breast Carcinoma: Diagnostic Criteria ...
33 Special Types of Invasive Breast Carcinoma: Diagnostic Criteria ... 33 Special Types of Invasive Breast Carcinoma: Diagnostic Criteria ...
Illustrative Case #2 Carcinoma + sarcoma = carcinosarcoma 10/8/2011 80
Osseous Differentiation (Osteosarcoma) Dx: Carcinosarcoma with OOsseous Differentiation Diff ti ti (Osteogenic Sarcoma) Prognosis of Metaplastic Carcinoma Rayson, et al. (Mayo Clinic). Annals of Oncology 10:413-419, 1999. • 3-year DFS was 40%. • 3-year OS was 71%. • 87% of MBC patients were node negative. • 10 chemo regimens used for metastatic disease - one partial response. • NNo responses tto tamoxifen t if in i 4 patients ti t with ith metastatic t t ti disease. di • Median survival after development of metastases was 8 mos. • Conclusions: Despite presenting more commonly as nodenegative disease, DFS and OS in MBC is decreased compared to typical adeno-carcinomas. Systemic therapy also appears to be less effective. • 5-year OS for matrix-producing carcinoma roughly 68%. • 5-year OS for invasive breast carcinoma (all types) roughly 75% 10/8/2011 81
- Page 31 and 32: Literature Summary: Correlation of
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- Page 35 and 36: CD10 SMA MIB-1 10/8/2011 33
- Page 37 and 38: Carter et al. Cancer 1977 & 1983
- Page 39 and 40: Differential Diagnosis: 1. Invasive
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- Page 43 and 44: SYNAPTOPHYSIN SMA 10/8/2011 41
- Page 45 and 46: Nassar et al. (AJSP 2006;30:501-7.)
- Page 47 and 48: Special Types of Invasive Breast Ca
- Page 49 and 50: Tubular carcinoma • It has been d
- Page 51 and 52: Tubular carcinoma Histopathology
- Page 53 and 54: Flat Epithelial Atypia When should
- Page 55 and 56: Microglandular adenosis + reticulin
- Page 57 and 58: mitosis ductal ductal, NST tubular
- Page 59 and 60: Treatment • Breast conservation t
- Page 61 and 62: Cribriform carcinoma Histopathology
- Page 63 and 64: Cribriform carcinoma Prognosis •
- Page 65 and 66: Cribriform Carcinoma Pearls of Path
- Page 67 and 68: Clinicopathological features Mucino
- Page 69 and 70: Case 4 Mucinous carcinoma Mixed muc
- Page 71 and 72: Treatment • Breast conservation a
- Page 73 and 74: Incipient mucocele-like lesion Cyst
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- Page 79 and 80: SMA Dx: Spindle-cell Breast Carcino
- Page 81: Dx: Pure Squamous Carcinoma 10/8/20
- Page 85 and 86: Spindle-cell Carcinoma of the Breas
- Page 87 and 88: Phyllodes y Tumors Phyllodes Tumor
- Page 89 and 90: Diagnosis: Benign g (Low-grade) Phy
- Page 91 and 92: Diagnosis: Malignant (High-grade) P
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- Page 97 and 98: Illustrative Case 10/8/2011 95
- Page 99 and 100: SMA Calponin 10/8/2011 97
- Page 101 and 102: Dx: Mixed Spindle-cell & Cl Classic
- Page 103 and 104: Dx: Adenomyoepithelioma, Epithelioi
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- Page 109 and 110: Case 1 • 40 year old female • B
- Page 111 and 112: What is your diagnosis? 1. Invasive
- Page 113 and 114: Case 4 • Irregular large breast m
- Page 115 and 116: Case 6 • Needle core biopsy of a
- Page 117 and 118: 343 What is your best diagnosis? 1.
- Page 119 and 120: 349 Case 9 What is your diagnosis?
- Page 121 and 122: Case 11 Case 11 Case 12 • A 68 ye
- Page 123 and 124: Case 13 • Needle core biopsy of a
- Page 125 and 126: What is your diagnosis? 1. Intracys
- Page 127 and 128: What is your best interpretation? 1
- Page 129 and 130: Case 18 What is your best interpret
- Page 131 and 132: Case 20 • 35 year old female with
Illustrative<br />
Case #2<br />
<strong>Carcinoma</strong> + sarcoma = carcinosarcoma<br />
10/8/2011<br />
80
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