33 Special Types of Invasive Breast Carcinoma: Diagnostic Criteria ...

• 17% recurred with recurrence rates equal
in both pure LCIS and LCIS+DCIS cases.
• All recurrences were IPSILATERAL.
• 50% of recurrences invasive carcinomas.
• Recurrence related to extent and cell type type.
• Recurrence Rate Among LCIS Types:
(10 lobules LCIS + large nuclei) = 41%
• I believe, CIS having mixed ductal & lobular
features, should be (at least in part) called DCIS -
this encourages complete excision.
• YET, I mention the concomitant LCIS pattern to
emphasize somewhat greater risk of bilateral
carcinoma (e (e.g., g “mixed mixed ductal & lobular CIS”) CIS ).
• This encourages adequate follow-up studies of
the contra-lateral breast.
WHO 2003
“The current recommended management
for lobular neoplasia is life long followup
with or without tamoxifen rx. Re-
excision i i should h ld bbe considered id d iin
cases
of massive acinar distention, and when
pleomorphic, signet ring, or necrotic
variants are identified at or close to the
margin.”
10/8/2011
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