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33 Special Types of Invasive Breast Carcinoma: Diagnostic Criteria ...

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43. Green I, McCormick B, Cranor M, et al. A comparateve study <strong>of</strong> pure tubular<br />

and tubulolobular carcinoma <strong>of</strong> breast. Am J Surg Pathol 1997;21:653-657<br />

44. Wheeler DT, Tai LH, Bratthauer GL, et al. Tubulolobular carcinoma <strong>of</strong> breast.<br />

An analysis <strong>of</strong> 27 cases <strong>of</strong> tumor with a hybrid morphology and<br />

immunopr<strong>of</strong>ile. Am J Surg Pathol 2004;28:1587-1593.<br />

Case 4:<br />

History: 57 y/o female with palpable breast mass. Patient was participating in<br />

the breast cancer awareness month function when she examined her own<br />

breasts and noticed the left breast mass. Mammogram found 2 cm suspicious<br />

mass at 5 o'clock position <strong>of</strong> the left breast<br />

Submitted diagnosis: <strong>Invasive</strong> mucinous carcinoma, "pure” (welldifferentiated<br />

invasive breast carcinoma, overall mBR grade 1; nuclear grade 1,<br />

tubular grade “1", mitotic grade 1).<br />

MUCINOUS CARCINOMA<br />

Background: Mucinous carcinoma contains large amounts <strong>of</strong> extracellular epithelial<br />

mucin, sufficient to be visible grossly, and recognizable microscopically surrounding<br />

and, sometimes, within tumor cells. These tumors have blunt, rather irregular borders.<br />

Mucin can be found in most carcinomas <strong>of</strong> the breast, but the term mucinous<br />

54

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