33 Special Types of Invasive Breast Carcinoma: Diagnostic Criteria ...

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Apocrine differentiation in lobular carcinoma of the breast. A morphologic, immunologic, and ultrastructural study. Hum Pathol 1984;15:134-140. 12. Walford N, Velden JT. Histiocytoid breast carcinoma: an apocrine variant of lobular carcinoma. Histopathology 1989;14:515-522. 13. Marino MJ, Livolsi VA. Signet-ring carcinoma of the female breast; a clinicopathologic analysis of 24 cases. Cancer 1981;48:1830-1837. 14. Steinbrecher JS, Silverberg SG. Signet-ring cell carcinoma of the breast. The mucinous variant of infiltrating lobular carcinoma? Cancer 1976;37:828-840. 15. Page DL, Anderson TJ, Sakamoto G. "Infiltrating lobular carcinoma." In: Page DL, Anderson TJ (eds), Diagnostic Histopathology of the Breast, pp. 219-226. Churchill Livingstone, New York, 1987. 16. Eusebi V, Magalhaes F, Azzopardi JG. Pleomorphic lobular carcinoma of the breast: an aggressive tumor showing apocrine differentiation Hum Pathol 1992;23:655-662. 17. Mazoujian G, Pinkus GS, Davis S, Haagensen DE. Immunohistochemistry of a gross cystic disease fluid protein (GCDFP-15) of the breast. A marker of apocrine epithelium and breast carcinomas with apocrine features. Am J Pathol 1983; 110:105-112. 18. Weidner N, Semple JP. Pleomorphic variant of invasive lobular carcinoma of the breast. Hum Pathol 1992;23:1167-1171. 19. Eusebi V, Foschini MP, Bussolati G, Rosen PP. Myoblastomatoid (histiocytoid) carcinoma of the breast. A type of apocrine carcinoma. Am J Surg Pathol 1995;19:553-562. 20. Frost AR, Terahata S, Yeh I-T, Siegel RS, Overmoyer B, Silverberg SG. The significance of signet-ring cells in infiltrating lobular carcinoma of the breast. Arch Pathol Lab Med 1995;119:64-68. 21. Cha I, Weidner N. Correlation of prognostic factors and survival with classical and pleomorphic variants of invasive lobular carcinoma. The Breast J 1996;2:385-393. 22. Silverstein MJ, Lewinsky BS, Waisman JR, Gierson ED, Colburn WJ, Senofsky GM, Gamagami P. Infiltrating lobular carcinoma. Is it different from infiltrating ductal carcinoma? Cancer 1994;73:1673-1677. 23. Henson D, Tarone R. A study of lobular carcinoma of the breast based on the Third National Cancer Survey in the United States of America. Tumori 1979;65:133-42. 24. Newman W. Lobular carcinoma of the female breast. Report of 73 cases. Ann Surg 1966;164:305-14. -27-
25. Richter GO, Dockerty MB, Clagett OT. Diffuse infiltrating scirrhous carcinoma of the breast. Special consideration of the single-filing phenomenon. Cancer 1967;20:363-70. 26. Ashikari R, Huvos AG, Urban JA. Robbins GF. Infiltrating lobular carcinoma of the breast. Cancer 1973;31:110-6. 27. Fechner RE. Histologic variants of infiltrating lobular carcinoma of the breast. Hum Pathol 1975;6:373-8. 28. Fechner RE. Infiltrating lobular carcinoma without lobular carcinoma in situ. Cancer 1972:29:1539-45. 29. Rosen PP. Lesser ML, Kinne DW Breast carcinoma at the extremes of age: a comparison of patients younger than 35 years and older than 75 years. J Surg Oncol 1985;28:90-6. 30. Oertel YC. Fine needle aspiration of the breast. Stoneham, Mass: Butterworth, 1987:145-9. 31. Borst MJ, Ingold JA. Metastatic patterns of invasive lobular versus invasive ductal carcinoma of the breast. Surgery 1993;114:637-641. 32. Harris M, Howell A, Chrissohou M, Swindell RI, Hudson M, Sellwood RA. A comparison of the metastatic pattern of infiltrating lobular carcinoma and infiltrating duct carcinoma of the breast. Br J Cancer 1984;50:23-30. 33. Smith DB, Howell A, Harris M, Bramwell VH, Sellwood RA. Carcinomatous meningitis associated with infiltrating lobular carcinoma of the breast. Eur J Surg Oncol 1985;11:33-6. 34. Klein MS, Sherlock R Gastric & colonic metastases from breast cancer. Am J Dig Dis 1972;17:881-6. 35. Gagnon Y, Tëtu B. Ovarian metastases of breast carcinoma. A clinicopathologic study of 59 cases. Cancer 1989;64:892-8. 36. Raju U, Ma CK, Shaw A. Signet ring variant of lobular carcinoma of the breast: a clinicopathologic and immunohistochemical study. Mod Pathol 1993;6:516- 520. 37. Hartmann WH, Sherlock R Gastroduodenal metastases from carcinoma of the breast. An adrenal steroid induced phenomenon. Cancer 1961;14:426-31. 38. Yoshida Y. Metastases and primary neoplasms of the stomach in patients with breast cancer. Am J Surg 1973:125:738-43. 39. Doglioni C; Dei Tos AP; Laurino L; Chiarelli C; Barbareschi M; Viale G. The prevalence of BCL-2 immunoreactivity in breast carcinomas and its clinicopathological correlates, with particular reference to oestrogen receptor status. Virchows Arch Pathol 1994;424:47-51. -28-
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33 Special Types of Invasive Breast
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Special Types of Invasive Breast Ca
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INVASIVE BREAST CARCINOMAS CONSIDER
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ER Neg. PR Neg. HER2 Neg. CK 5/6 Po
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Triple-negative Breast Carcinomas
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E-cadherin E-cadherin EGFR ++ ER ne
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ER/PR Positive HER2 Negative INVASI
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Tubulolobular Signet-ring Histiocyt
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Illustrative Example: 61 y/o female
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E-Cadherin ER PR 10/8/2011 17
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LCIS vs DCIS • Patients with lobu
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Examples of E-cadherin staining in
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Classic Low-grade DCIS - E-cadherin
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E-cadherin IHC CASE D 10/8/2011 25
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E-cadherin IHC CASE E 10/8/2011 27
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Literature Summary: Correlation of
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10/8/2011 31
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CD10 SMA MIB-1 10/8/2011 33
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Carter et al. Cancer 1977 & 1983
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Differential Diagnosis: 1. Invasive
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10/8/2011 39
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SYNAPTOPHYSIN SMA 10/8/2011 41
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Nassar et al. (AJSP 2006;30:501-7.)
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Special Types of Invasive Breast Ca
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Tubular carcinoma • It has been d
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Tubular carcinoma Histopathology
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Flat Epithelial Atypia When should
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Microglandular adenosis + reticulin
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mitosis ductal ductal, NST tubular
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Treatment • Breast conservation t
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Cribriform carcinoma Histopathology
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Cribriform carcinoma Prognosis •
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Cribriform Carcinoma Pearls of Path
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Clinicopathological features Mucino
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Case 4 Mucinous carcinoma Mixed muc
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Treatment • Breast conservation a
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Incipient mucocele-like lesion Cyst
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SMA Dx: Spindle-cell Breast Carcino
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Dx: Pure Squamous Carcinoma 10/8/20
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Osseous Differentiation (Osteosarco
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Spindle-cell Carcinoma of the Breas
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Phyllodes y Tumors Phyllodes Tumor
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Diagnosis: Benign g (Low-grade) Phy
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Diagnosis: Malignant (High-grade) P
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10/8/2011 91
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10/8/2011 93
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Illustrative Case 10/8/2011 95
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SMA Calponin 10/8/2011 97
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Dx: Mixed Spindle-cell & Cl Classic
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Dx: Adenomyoepithelioma, Epithelioi
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10/8/2011 103
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10/8/2011 105
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Case 1 • 40 year old female • B
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What is your diagnosis? 1. Invasive
Page 113 and 114: Case 4 • Irregular large breast m
Page 115 and 116: Case 6 • Needle core biopsy of a
Page 117 and 118: 343 What is your best diagnosis? 1.
Page 119 and 120: 349 Case 9 What is your diagnosis?
Page 121 and 122: Case 11 Case 11 Case 12 • A 68 ye
Page 123 and 124: Case 13 • Needle core biopsy of a
Page 125 and 126: What is your diagnosis? 1. Intracys
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Page 129 and 130: Case 18 What is your best interpret
Page 131 and 132: Case 20 • 35 year old female with
Page 133 and 134: Negative ER stain NEG ER Case 22
Page 135 and 136: What is your best interpretation? 1
Page 137 and 138: What is your diagnosis? 1. Secretor
Page 139 and 140: American Soiety of Clinical Patholo
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Page 143 and 144: INVASIVE BREAST CARCINOMAS THAT ARE
Page 145 and 146: of lymphoid cells between sheets of
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Page 149 and 150: molecular subtypes. Indeed, the pea
Page 151 and 152: In summary, basal-like breast cance
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Page 179 and 180: outcome of patients with intracysti
Page 181 and 182: Case 3: History: A 73 year old fema
Page 183 and 184: cases. In this small tubular carcin
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Page 189 and 190: 9. Bondeson L, Lindholm K. Aspirati
Page 191 and 192: 43. Green I, McCormick B, Cranor M,
Page 193 and 194: mucinous carcinoma (7,11,12,14). In
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Page 205 and 206: Case 6: History: 66 year old female
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cases: review of the literature and
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Case 7 the breast associated with l
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size (14). Metaplastic breast carci
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adenoma by others who prefer to avo
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survival rate than is usually repor
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it arises in other soft tissue site
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implies a relative risk for develop
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sclerosing adenosis wherein the str
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overgrowth (136). While acknowledgi
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As noted above, any soft-tissue sar
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J Med 73:1078-1082, 1973. 11. Barne
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40. Thorner PS, Kahn HJ, Baumal R,
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75. Fekete P, Petrek J, Majmudar B,
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microscopic, ultrastructural, and i
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2006 Apr;30(4):450-6 143. Liberman
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Case 8 Case history: A 50 year old
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secondary peripheral tumor nodules
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Definitive diagnosis of medullary c
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Pathol 1988;19:1340-6. 12. Rosen PP
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40. Di Bonito; Royen PM, Ziter FMH.
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Am J Clin Pathol 1979;72:383-389. 1
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