World Journal of Pharmaceutical research - WJPR!
World Journal of Pharmaceutical research - WJPR!
World Journal of Pharmaceutical research - WJPR!
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Manish Gunjan <strong>World</strong> <strong>Journal</strong> <strong>of</strong> <strong>Pharmaceutical</strong> <strong>research</strong><br />
13 Coleus<br />
forskohlii (26)<br />
14 Hemidesmus<br />
indicus (27)<br />
www.wjpr.net<br />
Lamiaceae whole<br />
plant<br />
Asclepiadaceae Cell<br />
culture<br />
extract<br />
both triglycerides and<br />
serum cholesterol were<br />
brought back to the<br />
baseline.<br />
- This plant extract (10%<br />
forskolin) at a dose <strong>of</strong> 500<br />
mg showed significant<br />
decrease in body weight<br />
(66.33 ± 3.00 to 63.96 ±<br />
3.10, p=0.0038), fat<br />
content (29.64 ± 2.19 to<br />
27.77 ± 2.27, p=0.0038),<br />
lean body mass (44.34 ±<br />
2.98 to 43.93 ± 3.01,<br />
p=0.0044) and basal<br />
metabolic rate (1379.1 ±<br />
74.4 to 1363.9 ± 77.5,<br />
p=0.0254) when given to<br />
fifteen volunteers twice a<br />
day with meals in an 8-<br />
weeks open-label study.<br />
This indicates that C.<br />
forskohlii extract has<br />
potential effect as an<br />
adjunct therapy in the<br />
treatment <strong>of</strong> obesity.<br />
- Cell culture extract<br />
<strong>of</strong> H.indicus (2, 4 and 16<br />
mg/kg, p.o) showed<br />
significant treatment<br />
reduction (p
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