World Journal of Pharmaceutical research - WJPR!
World Journal of Pharmaceutical research - WJPR!
World Journal of Pharmaceutical research - WJPR!
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Manish Gunjan <strong>World</strong> <strong>Journal</strong> <strong>of</strong> <strong>Pharmaceutical</strong> <strong>research</strong><br />
hence blocks the absorption <strong>of</strong> fat in the intestines. The most common adverse events <strong>of</strong><br />
Orlistat include oily faecal spotting, abdominal pain, and flatus with discharge, faecal<br />
urgency, fatty/oily stool, increased defecation, and faecal incontinence (8) . Another<br />
pharmacotherapy is the centrally acting antiobesity agent, namely, Sibutramine (Reductil),<br />
which produces unwanted side effects such as trouble sleeping, constipation, and dry mouth<br />
as well as increased heartbeat, increased blood pressure, awareness <strong>of</strong> the heartbeat<br />
(palpitations), headache, anxiety, or dizziness (9–11) . Consequently, the Food and Drug<br />
Administration (FDA) <strong>of</strong> the USA withdrew Sibutramine in October 2010. Surgical<br />
procedures such as gastric bypass operations are generally reserved for people with morbid<br />
obesity (BMI > 40) who instituted but failed an adequate exercise and diet program (with or<br />
without adjunctive drug therapy) or patients presenting with comorbid conditions such as<br />
hypertension, impaired glucose tolerance, diabetes mellitus, hyperlipidaemia, and obstructive<br />
sleep apnoea (12) . In addition to an increase in total body fat, a proportionally greater amount<br />
<strong>of</strong> abdominal fat compared with fat in the lower extremities or hips has been associated with<br />
increased risk for diabetes, hypertension, and risk factors for heart disease in both men and<br />
women. Current guidelines categorize men at increased relative risk for coronary artery<br />
disease, diabetes, and hypertension if they have a waist circumference greater than 40 inches<br />
(102 cm); women are at increased risk if their waist circumference exceeds 35 inches (88<br />
cm). Thus, an overweight person with abnormal fat patterning may be at high risk for these<br />
diseases even if that person is not considered obese by BMI criteria. (13) .<br />
MATERIAL AND METHODS<br />
Respondents were interviewed face- to- face using a survey questionnaire. Respondents<br />
needed to answer questions to test their awareness on the treatment using herbal medicine and<br />
physical activity for obesity.<br />
QUESTIONNAIRE<br />
The questionnaire was developed based on a literature <strong>of</strong> other similar surveys in the region.<br />
The questionnaires were made available in English. The respondents include allopathic<br />
doctor, herbalist, physiotherapist and patients. After we went through the questionnaire we<br />
concluded that major cause <strong>of</strong> obesity is lifestyle and we proposed some treatments by using<br />
herbs and exercise.<br />
www.wjpr.net<br />
BMI = Wt (kg)/Height(m 2 )<br />
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