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World Journal of Pharmaceutical research - WJPR!

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Manish Gunjan <strong>World</strong> <strong>Journal</strong> <strong>of</strong> <strong>Pharmaceutical</strong> <strong>research</strong><br />

2. Do you aware <strong>of</strong> any <strong>of</strong> this herbal medicine which is used for obesity? Tick as much as<br />

you know.<br />

Do you aware <strong>of</strong> any <strong>of</strong> this herbal medicine<br />

which is used for obesity? Tick as much as<br />

you know.<br />

www.wjpr.net<br />

No. <strong>of</strong><br />

Respondents<br />

(A) Aloe vera 5 14<br />

(B) Gymnema 5 14<br />

(C) Parsley 3 8<br />

(D) Kundru 4 11<br />

(E) Cascara 1 3<br />

(F) Commophora mukul/guggul 1 3<br />

(G) Hoordia gordonii 3 8<br />

(H) Zingiber <strong>of</strong>ficinale 4 11<br />

(I) Garcinia cambogia 3 8<br />

(J) Evening primrose oil 1 3<br />

(K) Marijuana/cannabis sativa 1 3<br />

(L) Pananx ginseng 5 14<br />

Percentage (%)<br />

Most herbalist think that Aloe vera, Gymnema, Pananx ginseng, Kundru and Zingiber<br />

<strong>of</strong>ficinale are using for obesity treatment. According to literature review, Aloe vera,<br />

Gymnema, parsley, Kundru, Cascara, Commophora mukul/Guggul, Hoordia gordonii,<br />

Zingiber <strong>of</strong>ficinale, Garcinia cambogia and Pananx ginseng all are the herbal drug which is<br />

used to treat obesity. Juice <strong>of</strong> aloe vera is rich in several vitamins, minerals, trace elements<br />

and amino acids. Internal intake <strong>of</strong> this juice as well as its external application can be used in<br />

treatment <strong>of</strong> many diseases like weight loss, hypertension, diabetes, high cholesterol, acne,<br />

eczema and some other skin disorders. Gymnema is one <strong>of</strong> the plants with potent anti diabetic<br />

properties and used for controlling obesity in the form <strong>of</strong> Gymnema tea. Kundru has<br />

antioxidant property, anti diabetic property and most important is its hypoglycemic action<br />

because <strong>of</strong> which its aqueous and ethanolic extracts can be used for control <strong>of</strong> obesity.<br />

Hydroxycitric acid, the active ingredient in the herbal compound Garcinia cambogia,<br />

competitively inhibits the extramitochondrial enzyme adenosine triphosphate-citrate (pro-<br />

3S)-lyase. As a citrate cleavage enzyme that may play an essential role in de novo lipogenesis<br />

inhibition, G cambogia is claimed to lower body weight and reduce fat mass in humans.<br />

1273

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