World Journal of Pharmaceutical research - WJPR!
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Manish Gunjan <strong>World</strong> <strong>Journal</strong> <strong>of</strong> <strong>Pharmaceutical</strong> <strong>research</strong><br />
Article Received on<br />
02 October 2012,<br />
THE ROLE OF HERBAL MEDICINE AND EXERCISE IN THE<br />
www.wjpr.net<br />
MANAGEMENT OF OBESITY<br />
* Manish Gunjan, Tarun Amalnerkar, Shobananair, Toh Su Fen, Hindran Kumar, Asif<br />
Revised on 15 October 2012,<br />
Accepted on 26 October 2012<br />
*Correspondence for<br />
Author:<br />
* Manish Gunjan<br />
Masterskill global college<br />
Ipoh,Malaysia .<br />
manish_14us@yahoo.com<br />
<strong>World</strong> <strong>Journal</strong> <strong>of</strong> <strong>Pharmaceutical</strong> <strong>research</strong><br />
Iqbal Chittur Mohammed and Vanitha<br />
Masterskill global college, Malaysia.<br />
ABSTRACT<br />
Obesity is the most prevalent, fatal, chronic, relapsing disorder <strong>of</strong> the<br />
21st century. It is likely that the increase in obesity will strain our<br />
healthcare system with millions <strong>of</strong> additional cases <strong>of</strong> diabetes, heart<br />
disease and disability. The aim <strong>of</strong> this study is to evaluate the efficacy<br />
and side effect by using herbal formulation and exercise together to<br />
promote weight loss as compared to placebo or herbal or exercise<br />
separately to give awareness among people for use <strong>of</strong> herbal medicine<br />
and exercise in the management <strong>of</strong> obesity. We went through<br />
questionnaire based survey and personal interview with patients,<br />
doctors, herbalists as well as Physiotherapist. After compiling and<br />
statistical analysis, we found that improper lifestyle such as lack <strong>of</strong><br />
exercise, unhealthy food intake is the major cause for obesity and herbal medicine together<br />
with exercise will be a better substitute in the management <strong>of</strong> obesity instead <strong>of</strong> taking herbal<br />
medicine alone.<br />
Volume 1, Issue 5, 1250-1280. Review Article ISSN 2277 – 7105<br />
Key words: Diabetes, Folk medicine, Physiotherapy, BMI.<br />
INTRODUCTION<br />
Obesity is now recognized as the most prevalent metabolic disease world-wide, reaching<br />
epidemic proportions in both developed and developing countries and affecting not only<br />
adults but also children and adolescents. The WHO has already declared obesity a global<br />
epidemic that constitutes one <strong>of</strong> the biggest current health problems. (1) This abnormality has<br />
persisted throughout the centuries, which have been characterized by markedly different<br />
environmental stresses and dietary habits .(2) Obesity is the most common metabolic disorder<br />
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<strong>of</strong> human and onc <strong>of</strong> the oldest documented diseases. An estimated 35 to45 percent <strong>of</strong> all<br />
U.S. women and 20 to 30 percent <strong>of</strong> all U.S. men are trying to lose weight at any given time,<br />
spending up to $40 billion each year to do so. Some <strong>of</strong> these people do not even need to lose<br />
weight. Others need to lose weight but not successful. Still others are successful. Weight- loss<br />
advice, then, does not apply equally to all overweight people. Some people may risk more in<br />
the process <strong>of</strong> losing weight than in remaining overweight. Others may reap significant health<br />
benefits with just modest weight loss. (4) The overweight problem is due to an actual increase<br />
in the fat component, or it can be due to malfunctioning glands. Today, it is estimated that<br />
there are more than 250 million obese people worldwide, equivalent to seven percent <strong>of</strong> the<br />
adult population. (5) In the United States, data from the second National Health and Nutrition<br />
Examination Survey (NHANES II) were used to define obesity in adults as a BMI <strong>of</strong> 27.3<br />
kg/m2 or more for women and 27.8 kg/m2 or more for men. These definitions were based on<br />
the gender-specific 85th-percentile values <strong>of</strong> BMI for persons 20 to 29 years <strong>of</strong> age. The<br />
WHO classification assigns an increasing risk for comorbid conditions—including<br />
hypertension, type 2 (non-insulin-dependent) diabetes mellitus, and cardiovascular disease--<br />
to persons with higher BMIs (see Table 1) relative to persons <strong>of</strong> normal weight (i.e., those<br />
with a BMI between 18.5 kg/m2 and 25 kg/m2).The WHO criteria for overweight is (BMI<br />
25 kg/m 2 ) and obesity ( 30 kg/m2), 67% <strong>of</strong> men and 62% <strong>of</strong> women are overweight . (6)<br />
Food intake is modified by a multitude <strong>of</strong> factors – physiological, psychological, and social,<br />
etc. Meal size seems to be controlled by a feedback loop in which signals from the<br />
gastrointestinal tract are transmitted to the hypothalamus after relay in the brainstem. An<br />
important afferent signal is cholecystokinin – a peptide secreted by the duodenum in response<br />
to mechanical and chemical stimuli. Cholecysokinin acts locally on cholecystokinin receptors<br />
in the gastrointestinal tract, the signal being transmitted to the brainstem by the vagus. The<br />
effect is to decrease food intake. Circulating cholecystokinin does not cross the blood-brain<br />
barrier but the peptide is also a neurotransmitter and acts on cholecystokinin B receptors in<br />
the brain to function as a satiety factor. Insulin stimulates leptin release from fat cells and it<br />
enters the CNS where it can decrease food intake by affecting the actions <strong>of</strong> NPY. However,<br />
insulin may also, in some circumstances, increase food intake, presumably indirectly, by an<br />
effect on blood glucose. Thus patients with type 2 diabetes mellitus usually gain weight when<br />
treated with insulin or sulfonylureas – an effect that is clinically important. (7) Current<br />
management <strong>of</strong> obesity by pharmacotherapy includes noncentrally acting antiobesity agents<br />
such as Orlistat (Xenical), which inhibits the action <strong>of</strong> the intestinal lipase enzymes and<br />
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hence blocks the absorption <strong>of</strong> fat in the intestines. The most common adverse events <strong>of</strong><br />
Orlistat include oily faecal spotting, abdominal pain, and flatus with discharge, faecal<br />
urgency, fatty/oily stool, increased defecation, and faecal incontinence (8) . Another<br />
pharmacotherapy is the centrally acting antiobesity agent, namely, Sibutramine (Reductil),<br />
which produces unwanted side effects such as trouble sleeping, constipation, and dry mouth<br />
as well as increased heartbeat, increased blood pressure, awareness <strong>of</strong> the heartbeat<br />
(palpitations), headache, anxiety, or dizziness (9–11) . Consequently, the Food and Drug<br />
Administration (FDA) <strong>of</strong> the USA withdrew Sibutramine in October 2010. Surgical<br />
procedures such as gastric bypass operations are generally reserved for people with morbid<br />
obesity (BMI > 40) who instituted but failed an adequate exercise and diet program (with or<br />
without adjunctive drug therapy) or patients presenting with comorbid conditions such as<br />
hypertension, impaired glucose tolerance, diabetes mellitus, hyperlipidaemia, and obstructive<br />
sleep apnoea (12) . In addition to an increase in total body fat, a proportionally greater amount<br />
<strong>of</strong> abdominal fat compared with fat in the lower extremities or hips has been associated with<br />
increased risk for diabetes, hypertension, and risk factors for heart disease in both men and<br />
women. Current guidelines categorize men at increased relative risk for coronary artery<br />
disease, diabetes, and hypertension if they have a waist circumference greater than 40 inches<br />
(102 cm); women are at increased risk if their waist circumference exceeds 35 inches (88<br />
cm). Thus, an overweight person with abnormal fat patterning may be at high risk for these<br />
diseases even if that person is not considered obese by BMI criteria. (13) .<br />
MATERIAL AND METHODS<br />
Respondents were interviewed face- to- face using a survey questionnaire. Respondents<br />
needed to answer questions to test their awareness on the treatment using herbal medicine and<br />
physical activity for obesity.<br />
QUESTIONNAIRE<br />
The questionnaire was developed based on a literature <strong>of</strong> other similar surveys in the region.<br />
The questionnaires were made available in English. The respondents include allopathic<br />
doctor, herbalist, physiotherapist and patients. After we went through the questionnaire we<br />
concluded that major cause <strong>of</strong> obesity is lifestyle and we proposed some treatments by using<br />
herbs and exercise.<br />
www.wjpr.net<br />
BMI = Wt (kg)/Height(m 2 )<br />
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STATISTICAL ANALYSIS<br />
After getting the answer, we followed the typical statistical analysis (bar graph) for proper<br />
analysis <strong>of</strong> data. Data was analyzed on the basis <strong>of</strong> MCQ`s.<br />
RESULT AND DISCUSSION<br />
TREATMENT<br />
HERBAL MEDICINE<br />
Sr.NO. BOTANICAL<br />
NAME<br />
1 Commiphora<br />
mukul (14)<br />
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FAMILY<br />
NAME<br />
PART<br />
USED<br />
Burseraceae Whole<br />
Plant.<br />
MOA FIGURE<br />
Guggul possesses strong<br />
disinfecting properties and<br />
is a weight loss and fat<br />
burning agent. It lowers<br />
elevated serum cholesterol<br />
and triglycerides, while<br />
maintaining or improving<br />
the HDL to LDL ratio.<br />
Studies report that it<br />
increases the production<br />
<strong>of</strong> thyroid hormone. Since<br />
this hormone breaks down<br />
cells <strong>of</strong> protein, fat and<br />
carbohydrates, this herb is<br />
believed to be promoting<br />
weight loss.<br />
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2 Garcinia<br />
cambogia (15)<br />
3 Panax ginseng<br />
(16)<br />
4 Cissus<br />
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(17)<br />
quadrangularis<br />
Guttiferae Gum resin - Garcinia<br />
Cambogia is a natural<br />
suppressor for appetite. It<br />
helps to suppress the<br />
Appetite and boost up the<br />
metabolism naturally. It<br />
acts on elimination <strong>of</strong><br />
excess fat from the body<br />
as it does not allow body<br />
to store excess <strong>of</strong> fat.<br />
Araliaceae Root - panax ginseng may<br />
encourage the body to rely<br />
on energy stores and burn<br />
calories more efficiently<br />
during exercise<br />
Vitaceae Stem - They also brought<br />
significant reductions in<br />
weight, body fat, total<br />
cholesterol,<br />
LDLcholesterol,<br />
triglycerides, and fasting<br />
blood glucose levels over<br />
the respective study<br />
periods in a double-blind<br />
placebo controlleddesign,<br />
involving initially 168<br />
overweight and obese<br />
persons<br />
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5 Gymnema<br />
sylvestre (18)<br />
6. Zingiber<br />
7. Radix<br />
8.<br />
<strong>of</strong>ficinale (19)<br />
platycodi<br />
(20,21)<br />
Erythrina<br />
vareigata (22)<br />
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Asclepiadaceae leaves and<br />
roots<br />
Zingiberaceae Ginger<br />
extract<br />
lowers triglycerides and<br />
“bad cholesterol<br />
- The<br />
phytochemical, gingerol<br />
and shogaol increase the<br />
metabolic rate and thus<br />
help to “burn <strong>of</strong>f”<br />
excessive fat and also<br />
suppress the<br />
absorption <strong>of</strong> calorie-<br />
dense dietary fats from the<br />
intestines.<br />
Campanulaceae dried root The aqueous extract <strong>of</strong><br />
Fabaceae<br />
Leaf<br />
extract<br />
Platycodi radix may<br />
inhibit the intestinal<br />
absorption <strong>of</strong> dietary fat<br />
by inhibiting its<br />
hydrolysis<br />
- hypolipidaemic,<br />
anti obesity effect in<br />
Siddha system <strong>of</strong><br />
medicine<br />
- Leaf extract has a<br />
high total phenol content,<br />
beneficially altered lipid<br />
parameters and reduced<br />
body weight.<br />
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9. Nigella sativa<br />
Linn<br />
10. Achyranthes<br />
aspera (23)<br />
11. Allium<br />
sativum (24)<br />
12. Acorus<br />
calamus (25)<br />
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Ranunculaceae Seeds - reduce cholesterol,<br />
Amaranthaceae Whole<br />
plant<br />
Alliaceae Whole<br />
plant<br />
triglyceride and glucose<br />
levels<br />
- The alcoholic<br />
extract <strong>of</strong> this plant at<br />
100mg/kg dose, lowered<br />
total serum cholesterol<br />
(TC) and phospholipid<br />
(PL), triglyceride (TG)<br />
and total. lipid (TL) levels<br />
by 60, 51, 33 and 53<br />
percent, respectively in<br />
triton-induced<br />
hyperlipidemic rats.<br />
- Lower blood<br />
cholesterol (fat) levels<br />
Araceae Tannins - Tannins from this<br />
plant at 10mg/kg dose<br />
decreased the serum<br />
cholesterol and<br />
triglyceride levels in rats<br />
fed with atherogenic<br />
diet.At a dose <strong>of</strong> 20mg/kg<br />
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13 Coleus<br />
forskohlii (26)<br />
14 Hemidesmus<br />
indicus (27)<br />
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Lamiaceae whole<br />
plant<br />
Asclepiadaceae Cell<br />
culture<br />
extract<br />
both triglycerides and<br />
serum cholesterol were<br />
brought back to the<br />
baseline.<br />
- This plant extract (10%<br />
forskolin) at a dose <strong>of</strong> 500<br />
mg showed significant<br />
decrease in body weight<br />
(66.33 ± 3.00 to 63.96 ±<br />
3.10, p=0.0038), fat<br />
content (29.64 ± 2.19 to<br />
27.77 ± 2.27, p=0.0038),<br />
lean body mass (44.34 ±<br />
2.98 to 43.93 ± 3.01,<br />
p=0.0044) and basal<br />
metabolic rate (1379.1 ±<br />
74.4 to 1363.9 ± 77.5,<br />
p=0.0254) when given to<br />
fifteen volunteers twice a<br />
day with meals in an 8-<br />
weeks open-label study.<br />
This indicates that C.<br />
forskohlii extract has<br />
potential effect as an<br />
adjunct therapy in the<br />
treatment <strong>of</strong> obesity.<br />
- Cell culture extract<br />
<strong>of</strong> H.indicus (2, 4 and 16<br />
mg/kg, p.o) showed<br />
significant treatment<br />
reduction (p
Manish Gunjan <strong>World</strong> <strong>Journal</strong> <strong>of</strong> <strong>Pharmaceutical</strong> <strong>research</strong><br />
15 Hibiscus<br />
sabdariffa (28)<br />
16 Lagerstroemia<br />
speciosa (29)<br />
17 Momordica<br />
charantia (30)<br />
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Malvaceae Hibiscus<br />
extract<br />
atherogenic diet for first<br />
30 (l-30) days. When<br />
atherogenic diet and cell<br />
culture extract were given<br />
together for 60 (l-60) days<br />
there was significant<br />
(p
Manish Gunjan <strong>World</strong> <strong>Journal</strong> <strong>of</strong> <strong>Pharmaceutical</strong> <strong>research</strong><br />
18 Myristica<br />
fragrans (31)<br />
19 Panax<br />
20 Piper<br />
(32, 33)<br />
japonicus<br />
nigrum (34)<br />
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and VLDL-CH levels in<br />
serum samples.<br />
Myristicaceae Seed - It lowered the<br />
lipoprotein lipid levels,<br />
total cholesterol, LDL<br />
cholesterol and<br />
triglycerides. HDL<br />
cholesterol was not<br />
significantly affected.<br />
Total cholesterol, HDL<br />
and LDL: HDL ratios<br />
were also significantly<br />
lowered. It lowered the<br />
level <strong>of</strong> total cholesterol<br />
in the heart and liver.<br />
Aralioideae Rhizomes They inhibit intestinal<br />
Piperaceae Seed<br />
absorption <strong>of</strong> dietary fat<br />
through the inhibition <strong>of</strong><br />
pancreatic lipase activity.<br />
-<br />
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21 Plumbago<br />
zeylanica (35)<br />
22 Solanum<br />
melongena &<br />
Solanum<br />
gilo (36)<br />
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Plumbaginaceae Root - Antihyperlipidemic<br />
Solanaceae Whole<br />
fruit<br />
- The aqueous extract at all<br />
doses demonstrated a<br />
significant (p
Manish Gunjan <strong>World</strong> <strong>Journal</strong> <strong>of</strong> <strong>Pharmaceutical</strong> <strong>research</strong><br />
24 Hoodia<br />
gordonii<br />
(38)<br />
25 Coccinia<br />
grandis or<br />
kundru (39)<br />
26 Triphala (40)<br />
27 Cabbage<br />
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Apocynaceae<br />
Cucurbitaceae<br />
Stems and<br />
roots<br />
Combretaceae Fruit taken<br />
digestion and assimilation<br />
<strong>of</strong> foods.<br />
- appetite suppressant<br />
- This active ingredient<br />
is a steroidal glycoside,<br />
due to which the brain<br />
does not sense hunger.<br />
Fruit - Increasing Energy,<br />
without<br />
seed<br />
Improving Digestion, and<br />
weight loss and are non-<br />
FDA reviewed or<br />
approved, natural<br />
alternatives, to use for<br />
Obesity.<br />
- Help in proper<br />
distribution <strong>of</strong> fat.<br />
Brassicaceae Leafy head - Inhibits the<br />
conversion <strong>of</strong> sugar and<br />
other carbohydrates into<br />
fat.<br />
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28 Tomato<br />
29 Rhamnus<br />
30 Aloe<br />
purshlanus /<br />
cascara (41)<br />
barbadensis /<br />
aloe vera (42)<br />
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Solanaceae Fruit - Fruit pectin and<br />
other edible fibers in<br />
tomato are easy to<br />
produce satiety feel,<br />
helping to absorb<br />
redundant fat and excrete<br />
together, and so reducing<br />
food fat intake. Edible<br />
fibers also help to<br />
promote motility <strong>of</strong><br />
stomach and intestine,<br />
reducing constipation.<br />
Rhamnaceae Bark - Works as a laxative<br />
Asphodelaceae Central<br />
part<br />
- Increase bowel<br />
movement<br />
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31 Allium cepa /<br />
onion<br />
32 Zea may’s /<br />
corn<br />
33 Ma huang (43)<br />
34 Dandelion (44)<br />
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Lilliaceae Bulb - lowers blood<br />
Poaceae Whole<br />
corn<br />
Ephedraceae Stem and<br />
branches<br />
cholesterol level<br />
- provides low<br />
calorie<br />
- Boost your<br />
metabolism<br />
- Suppress your<br />
appetite<br />
- Increase your<br />
energy<br />
- Turn your body<br />
into a calorie burning<br />
furnace through<br />
thermogenics<br />
Asteraceae Roots - It is an excellent<br />
diuretic leads to weight<br />
loss by reducing the water<br />
content <strong>of</strong><br />
the body<br />
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35 Green tea (45)<br />
36 Grape seed (46)<br />
EXERCISE FOR OBESITY (47)<br />
1. Pranamasana - salute.<br />
2. Hastauttanasana<br />
3. Padhastasana<br />
4. Ashwa Sanchalnasana.<br />
5. Parvatasana - mountain pose.<br />
6. Sashtang dandawat - lie down.<br />
7. Bhujangaasan - cobra pose.<br />
8. Parvatasana.<br />
9. Ashwa Sanchalasana<br />
10. Padhastasana<br />
11. Hastuttanasana<br />
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Theaceae Leaf - This means that<br />
these leaves, when<br />
consumed, can raise the<br />
body’s metabolism.<br />
Clinical studies show that<br />
green tea can boost your<br />
energy levels, increase the<br />
metabolism, and thereby<br />
promote weight loss.<br />
Vitaceae. Seed - grapes and grape<br />
seed extracts contain<br />
potent antioxidant and<br />
anti-inflammatory<br />
properties that may<br />
improve overall health<br />
and also prove to be an<br />
effective tool in fighting<br />
obesity and assisting in<br />
weight loss.<br />
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12. Pranamasana<br />
13. Garudasana (Eagle pose)<br />
14. Gamukhasana (Cow's face pose)<br />
15. Parighasana (Gate pose)<br />
16. Pavanmuktasana (Gas releasing pose)<br />
17. Aerobic dance (48)<br />
18. Fitness walking (49)<br />
19. Jumping rope<br />
20.Types <strong>of</strong> Exercises (50)<br />
Walking<br />
Running/Jogging<br />
Swimming<br />
Cycling<br />
SURVEY BASED RESULTS<br />
PATIENT<br />
1. Which is your favorite snack?<br />
What are you favourite snack? No. <strong>of</strong><br />
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Respondents<br />
(A) Salty snack: chips, cracker 3 14.5<br />
(B) Baked food: cookies, donuts 6 28.5<br />
(C) Other sweet: candy, chocolate 6 28.5<br />
(D) All <strong>of</strong> the above 6 28.5<br />
Percentage (%)<br />
Based on the above data it is clear that most <strong>of</strong> the patients like snacks, chips, cookies,<br />
crackers, sweet, candy and so on. 28.5% patients said that these are their favorite food.<br />
According to the literatures these foods contain more fat and carbohydrate which can lead to<br />
obesity, hence should consume in little amount.<br />
2. Do you take any <strong>of</strong> the following steps when you feel your weight goes beyond a certain<br />
threshold?<br />
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Do you take any <strong>of</strong> the following steps when<br />
you feel your weight goes beyond a certain<br />
threshold?<br />
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No. <strong>of</strong><br />
Respondents<br />
(A) Reduce food intake 11 55<br />
(B) Increase physical activity 4 20<br />
(C) Take medication 0 0<br />
(D) My weight does not change 5 25<br />
Percentage (%)<br />
55% students said that they reduce food intake when they feel their weight goes beyond a<br />
certain threshold. whereas 20% students feel that they should increase their physical activity.<br />
According to the literature review, we found that an obese patient should reduce the food<br />
intake and increase their physical activity. Reduce food intake should be the first step an<br />
obese patient should do.<br />
3. Do you know what obesity is and how it affects human health?<br />
Do you know what obesity is and how is<br />
affects human health?<br />
No. <strong>of</strong><br />
Respondents<br />
(A) Yes 12 60<br />
(B) Something I know about obesity 8 40<br />
(C) I don’t know about obesity 0 0<br />
Percentage (%)<br />
most patients are aware about obesity.60% patients answered that they know very well about<br />
obesity and 40% <strong>of</strong> patient knows something about obesity. From this bar graph we can<br />
discuss that most patients have the knowledge on what is obesity.<br />
4. What is the main cause <strong>of</strong> obesity?<br />
What is the main cause <strong>of</strong> obesity?<br />
No. <strong>of</strong><br />
Respondents<br />
(A) Lack <strong>of</strong> exercise 6 28.5<br />
(B) Unhealthy food 3 14.5<br />
(C) Stress 0 0<br />
(D)All <strong>of</strong> the above 12 57.0<br />
Percentage (%)<br />
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28.5% patient answered lack <strong>of</strong> exercise, 14.5% patient answered unhealthy food and 57.0%<br />
patient answered all <strong>of</strong> the above. To avoid that the students should eat healthy food like<br />
vegetable, fruit and cereal and increase physical activity like aerobic, running, cycling. Thus,<br />
exercise will also reduce stress. Based on the literature, all the above three answer is the<br />
cause <strong>of</strong> obesity. Hence,most <strong>of</strong> the patient answered correctly that cause <strong>of</strong> obesity is lack <strong>of</strong><br />
exercise, unhealthy food and stress.<br />
5. How to get good healthy lifestyle?<br />
How to get good healthy lifestyle?<br />
www.wjpr.net<br />
No. <strong>of</strong><br />
Respondents<br />
(A) Visit doctor to monitor your health 17 85<br />
(B) Smoking 1 5<br />
(C) Drinking Alcohol 0 0<br />
(D) Just eat the food that you like 2 10<br />
Percentage (%)<br />
Most <strong>of</strong> the patients choose visit doctor to monitor your health from the data we can conclude<br />
that the patients have knowledge about their healthy lifestyle and aware about their health.<br />
6. Do you think weight management is important in healthy lifestyle?<br />
Do you think weight management is important<br />
in healthy lifestyle?<br />
No. <strong>of</strong><br />
Respondents<br />
(A) Yes 16 80<br />
(B) No 4 20<br />
Percentage (%)<br />
80% patients answered yes and 20% patients answered no. Most <strong>of</strong> patients answered yes<br />
because they are aware that obesity can lead to many diseases. That shows that patients are<br />
aware <strong>of</strong> disease concern to obesity.<br />
7. What are the disease caused by obesity?<br />
What are the disease caused by obesity? No. <strong>of</strong><br />
Respondents<br />
(A) Diabetes 10 45.5<br />
(B) Hypertension 7 31.8<br />
Percentage (%)<br />
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(C) Cancer 0 0<br />
(D) All <strong>of</strong> the above 5 22.7<br />
45.5% patients answered diabetes, 31.8% patients answered hypertension and 22.7% patients<br />
answered all <strong>of</strong> the above. According to literature review, we found that the main disease that<br />
causes obesity is diabetes. From the above data we can conclude that most <strong>of</strong> the patient<br />
answered correctly that diabetes is the disease caused by obesity.<br />
8. Do you think that physical activity is lacking among Malaysians?<br />
Do you think that physical activity is lacking<br />
among Malaysians<br />
www.wjpr.net<br />
No. <strong>of</strong><br />
Respondents<br />
(A) Yes 16 80<br />
(B) No 4 20<br />
Percentage (%)<br />
80% <strong>of</strong> patients think that physical activity is lacking among Malaysians, whereas 20% <strong>of</strong><br />
patient answered no. According to the literature, physical activity is lacking among<br />
Malaysians because <strong>of</strong> their stressful work and less time. They suggested that physical<br />
activity like walking, cycling, swimming for about 30 minutes can reduce weight.<br />
9. How <strong>of</strong>ten do you exercise?<br />
How <strong>of</strong>ten do you exercise? No. <strong>of</strong><br />
Respondents<br />
(A) Everyday 2 10<br />
(B) Weekly once 9 45<br />
(C) Monthly once 0 0<br />
(D) None 9 45<br />
Percentage (%)<br />
45% <strong>of</strong> patient do exercise weekly once and the equal amount <strong>of</strong> patient do not do exercise at<br />
all. According to the literature, we should do exercise three times a week for 30-60 minutes.<br />
This is one <strong>of</strong> the vital factor which can lead to obesity.<br />
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10. What type <strong>of</strong> exercise you do daily?<br />
What type <strong>of</strong> exercise you do daily?<br />
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No. <strong>of</strong><br />
Respondents<br />
(A) Walking 10 43.5<br />
(B) Jogging 5 21.7<br />
(C) Gym exercise 1 4.5<br />
(D) None 3 13.0<br />
(E)Other 4 17.3<br />
Percentage (%)<br />
43.5 % students choose walking, 21.7% students choose jogging, 4.5% students choose gym<br />
exercise, 13% students choose none and 17.3% students choose other. There are many<br />
physical activities one can do like swimming, yoga, aerobic, skipping, handball, basketball,<br />
golf etc. we can conclude that most <strong>of</strong> the students like to walking as a exercise. According<br />
to the literature survey, we should do exercised three times a week for 12 weeks for duration<br />
30-60 minutes.<br />
11. Do you think herbal medicine is good in the management <strong>of</strong> obesity?<br />
Do you think herbal medicine is good in the<br />
management <strong>of</strong> obesity?<br />
No. <strong>of</strong><br />
Respondents<br />
(A) Yes 15 75<br />
(B) No 5 25<br />
Percentage (%)<br />
75% students answered yes and 25% students answered no. Herbal medicine is good because<br />
it doesn’t have much side effect to our body. We can use herbal medicine as a supplement to<br />
reduce body weight. From the data obtained we can conclude that herbal medicine is good in<br />
the management <strong>of</strong> obesity.<br />
12. Have you tried any modern medicine in your weight management?<br />
Have you tried any modern medicine in your<br />
weight management?<br />
No. <strong>of</strong><br />
Respondents<br />
(A) Yes 7 35<br />
(B) No 13 56.5<br />
Percentage (%)<br />
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35% students answered yes and 56.5% students answered no. This data shows that some <strong>of</strong><br />
the students did not tried modern medicine because they are aware <strong>of</strong> side effects <strong>of</strong> modern<br />
medicine. Some <strong>of</strong> the students answered that they use the herbal life product.<br />
13. Do you agree that exercise and herbal medicine together in management <strong>of</strong> obesity will<br />
be better and effective than using only exercise or herbal medicine separately?<br />
Do you agree that exercise and herbal<br />
medicine together in management <strong>of</strong> obesity<br />
will be better and effective than using only<br />
exercise or herbal medicine separately?<br />
www.wjpr.net<br />
No. <strong>of</strong><br />
Respondents<br />
(A) Yes, I agree 16 70<br />
(B) No, I am not agree 4 30<br />
Percentage (%)<br />
exercise and herbal medicine together in management <strong>of</strong> obesity will be better and effective<br />
than using only exercise or herbal medicine separately. 70% students answered yes, I agree<br />
and 30% students answered no, I am not agree. According to <strong>research</strong> published in scientific<br />
esteemed journals, combination <strong>of</strong> the both is more effective than using only exercise or<br />
herbal medicine separately.<br />
DOCTOR<br />
1. Which one <strong>of</strong> BMI range is consider obesity?<br />
Which one <strong>of</strong> BMI range is consider obesity? No. <strong>of</strong><br />
Respondents<br />
(A) < 18.5 0 0<br />
(B) 18.5 -25.0 0 0<br />
(C) 25.0- 30.0 4 31<br />
(D) >30.0 9 69<br />
Percentage (%)<br />
69% doctors answered correctly which is >30.0. 31% <strong>of</strong> doctors’ answer 25.0- 30.0. Body<br />
mass index should be expressed as weight (kg) divided by height (m 2 ), according to this<br />
formula we can calculate a person`s BMI. The correct answer for obesity according to BMI<br />
table in literature is > 30.0<br />
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2. What is the common reason for obesity?<br />
What is the common reason for obesity? No. <strong>of</strong><br />
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Respondents<br />
(A) Unhealthy eating 9 56<br />
(B) Lack <strong>of</strong> physical activity 7 44<br />
(C) Starvation 0 0<br />
(D) Other 0 0<br />
Percentage (%)<br />
56% doctors consider unhealthy eating is the common reason for obesity but 44% doctors<br />
answer that common reason for obesity is lack <strong>of</strong> physical activity. According to literature<br />
review, common reason for obesity are genetic factors, over consumption, sedentary lifestyle,<br />
stress, health factor. Obesity is a silent killer. From the graft we know that answer given by<br />
doctors is accurately.<br />
3. What do you suggest your patient to do to reduce weight?<br />
What do you suggest your patient to do to<br />
reduce weight?<br />
No. <strong>of</strong><br />
Respondents<br />
(A) Diet 11 48<br />
(B) Exercise 7 30<br />
(C) Take herbal medicine 4 18<br />
(D) Take modern medicine 1 4<br />
(E) Other 0 0<br />
Percentage (%)<br />
doctors suggest diet for their patient to reduce weight. 30% doctors suggest exercise, 18%<br />
doctors suggest taking herbal medicine and 4% doctors suggest take modern medicine. Diet is<br />
deliberate selection <strong>of</strong> food to control body weight or nutrient intake. Exercise is any bodily<br />
activity that maintains physical fitness , overall health and wellness. Conclusion is most <strong>of</strong><br />
the doctors will suggest diet and exercise to their patient to reduce weight.<br />
4. In your opinion which medicine will give more side effect in the treatment <strong>of</strong> obesity?<br />
In your opinion which medicine will give<br />
more side effect in the treatment <strong>of</strong> obesity?<br />
No. <strong>of</strong><br />
Respondents<br />
Percentage (%)<br />
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(A) Herbal medicine 4 25<br />
(B) Modern medicine 6 38<br />
(C) Combination <strong>of</strong> both 2 12<br />
(D) Combination with exercise 4 25<br />
25 % doctors answer herbal medicine and combination with exercise(herbal medicine +<br />
modern medicine + exercise) give more side effect. 38% doctors consider that modern<br />
medicine give more side effect. 12% doctors answer combination <strong>of</strong> both( herbal medicine +<br />
modern medicine). The correct answer is modern medicine according to literature and most<br />
<strong>of</strong> the doctor is answering correctly.<br />
HERBALIST<br />
1. Do you think herbal medicine will be more effective and safer than modern medicine?<br />
Do you think herbal medicine will be more<br />
effective and safer than modern medicine?<br />
www.wjpr.net<br />
No. <strong>of</strong><br />
Respondents<br />
(A) Yes 5 100<br />
(B) No 0 0<br />
Percentage (%)<br />
100% herbalist think that herbal medicine will be more effective and safer than modern<br />
medicine. We found that if herbal medicine correct selection <strong>of</strong> the corresponding therapeutic<br />
strategies and principles that guide the choice <strong>of</strong> herbs and herbal formulas. Then, it is<br />
prepared and used appropriately, it can be more safe and effective compare with modern<br />
medicine. Natural health medicine has been documented to have less or no side effects when<br />
compared to its chemical counterparts. That is because natural health medicine is generally<br />
made with products taken out <strong>of</strong> nature without being refined. That means that the medicine<br />
is made out <strong>of</strong> natural ingredients that will work in conjunction with the body; whereas their<br />
refined counterparts might have an adverse affect. Option A is choose by most herbalist and it<br />
is correct.<br />
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2. Do you aware <strong>of</strong> any <strong>of</strong> this herbal medicine which is used for obesity? Tick as much as<br />
you know.<br />
Do you aware <strong>of</strong> any <strong>of</strong> this herbal medicine<br />
which is used for obesity? Tick as much as<br />
you know.<br />
www.wjpr.net<br />
No. <strong>of</strong><br />
Respondents<br />
(A) Aloe vera 5 14<br />
(B) Gymnema 5 14<br />
(C) Parsley 3 8<br />
(D) Kundru 4 11<br />
(E) Cascara 1 3<br />
(F) Commophora mukul/guggul 1 3<br />
(G) Hoordia gordonii 3 8<br />
(H) Zingiber <strong>of</strong>ficinale 4 11<br />
(I) Garcinia cambogia 3 8<br />
(J) Evening primrose oil 1 3<br />
(K) Marijuana/cannabis sativa 1 3<br />
(L) Pananx ginseng 5 14<br />
Percentage (%)<br />
Most herbalist think that Aloe vera, Gymnema, Pananx ginseng, Kundru and Zingiber<br />
<strong>of</strong>ficinale are using for obesity treatment. According to literature review, Aloe vera,<br />
Gymnema, parsley, Kundru, Cascara, Commophora mukul/Guggul, Hoordia gordonii,<br />
Zingiber <strong>of</strong>ficinale, Garcinia cambogia and Pananx ginseng all are the herbal drug which is<br />
used to treat obesity. Juice <strong>of</strong> aloe vera is rich in several vitamins, minerals, trace elements<br />
and amino acids. Internal intake <strong>of</strong> this juice as well as its external application can be used in<br />
treatment <strong>of</strong> many diseases like weight loss, hypertension, diabetes, high cholesterol, acne,<br />
eczema and some other skin disorders. Gymnema is one <strong>of</strong> the plants with potent anti diabetic<br />
properties and used for controlling obesity in the form <strong>of</strong> Gymnema tea. Kundru has<br />
antioxidant property, anti diabetic property and most important is its hypoglycemic action<br />
because <strong>of</strong> which its aqueous and ethanolic extracts can be used for control <strong>of</strong> obesity.<br />
Hydroxycitric acid, the active ingredient in the herbal compound Garcinia cambogia,<br />
competitively inhibits the extramitochondrial enzyme adenosine triphosphate-citrate (pro-<br />
3S)-lyase. As a citrate cleavage enzyme that may play an essential role in de novo lipogenesis<br />
inhibition, G cambogia is claimed to lower body weight and reduce fat mass in humans.<br />
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Antiobesity effect <strong>of</strong> wild ginseng in male obese leptin-deficient mice was evaluated. Pananx<br />
ginseng able to loss <strong>of</strong> body weight and decrease in blood glucose levels .From this we able<br />
to know that most herbalist got the right answer.<br />
3. Have you suggested any <strong>of</strong> your patients to use herbal medicine in combination with<br />
exercise?<br />
Have you suggested any <strong>of</strong> your patients to<br />
use herbal medicine in combination with<br />
exercise?<br />
www.wjpr.net<br />
No. <strong>of</strong><br />
Respondents<br />
(A) Yes 3 60<br />
(B) No 2 40<br />
Percentage (%)<br />
60% herbalist answer yes, they will suggested any <strong>of</strong> their patient to use herbal medicine in<br />
combination with exercise. 40% herbalist answer no. The correct answer is yes according to<br />
literature because herbal medicine(collection <strong>of</strong> descriptions <strong>of</strong> plants put together for<br />
medicinal) and exercise put together for medicinal purposes which produce therapeutic effect<br />
on controlling weight gain and reducing weight. Most herbalist answer correctly because<br />
combination <strong>of</strong> herbal medicine and exercise in management <strong>of</strong> obesity is more effective<br />
compare with only use herbal medicine or only exercise to reduce weight according to<br />
literature.<br />
PHYSIOTHERAPISTS<br />
1. Do you think that physical activity is lacking among Malaysians<br />
Do you think that physical activity is lacking<br />
among Malaysians<br />
No. <strong>of</strong><br />
Respondents<br />
(A) Yes 9 90<br />
(B) No 1 10<br />
Percentage (%)<br />
90% physiotherapist answered yes and 10% physiotherapist answered no. Based on the data<br />
we can assume that exercise is important for obese patient to reduce their weight. Physical<br />
activity among Malaysia is lacking because <strong>of</strong> the busy lifestyle. They do not concern about<br />
their health and does not spend time for exercise<br />
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2. What are the exercises you suggest for obese patient?<br />
Most <strong>of</strong> the physiotherapist stated that aerobic exercise will be more helpful to reduce<br />
weight.Most <strong>of</strong> the physiotherapist suggested aerobic exercise like jogging, walking, cycling,<br />
and swimming. From literature review there are many exercise that you can suggest to obese<br />
patient for example indoor activities- sport games: basketball, handball, korfball (Dutch<br />
sports game), field hockey; outdoor activities- Triathlon: Subsequently exercising on either a<br />
normal bicycle or a mountain bike and a kick board followed by swimming and water polo<br />
and aqua jogging/aqua fitness. Based on the evidence from the physiotherapies are correct.<br />
3. How long we should exercise per day?<br />
The physiotherapist suggested that duration obese people should exercise between 20-60<br />
minutes per day depend on person’s health statusand also depend on our B.M.R.and Age.<br />
From literature review we should exercise three times a week for 12 week. The time duration<br />
is 30-60 minutes. The answer from the phsiotherapist are correct.<br />
4. Is there any side effect in doing certain exercise? If yes what are they?<br />
Yes, the side effect are muscle fatigue, muscle soreness, extreme heavy exercise can lead to<br />
heart failure in underlying ischaemic heart disease patient, jogging is not encouraged as if<br />
causes damage to hip, knee and ankle joint. When you exercise too vigorous and not suitable<br />
to your muscle strength. Precaution should be taken for cardiac patients asthamatic. If you are<br />
old and have some underlying bone related problem, avoid bearing exercises. According to<br />
the literature review side effect in doing certain exercise may contribute to further lowering<br />
<strong>of</strong> BP by attenuating the sympathetic nervous activity in the trained state.<br />
5. What are the food supplement we should take after exercise?<br />
The food supplement we should take after exercise that suggested by physioterapies are<br />
lemon water, light meal, egg(avoid yellow part), soup protein rich diet, supplement <strong>of</strong><br />
carbohydrate and vitamin, taking balance diet include vegeatable, fruit and cereal, energetic<br />
liquid diet and nutritional supplement. Based on literature review food supplement should<br />
increase consumption <strong>of</strong> grain, cereals and fibre as well as vegetables and fruit, and to<br />
substitute low-fat dairy products and meats for full- or high-fat alternatives. The answered<br />
from physiotherapies are correct.<br />
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CONCLUSION<br />
We have done a survey on role <strong>of</strong> herbal medicine and exercise in the management <strong>of</strong><br />
obesity. After going through the questionnaires, we can conclude that improper lifestyle such<br />
as lack <strong>of</strong> exercise, unhealthy food intake and stress is the major cause for obesity and also it<br />
is a multifactorial disorder. The age onset <strong>of</strong> obesity is late teens. According to the survey we<br />
got to know that most <strong>of</strong> the patients are consuming unhealthy food like snacks, chocolates,<br />
sweets which is the mainly causing obesity. Foods with high amount <strong>of</strong> carbohydrate also can<br />
cause obesity. Other than that, based on our interview with doctor they suggest that diet and<br />
exercise for the treatment <strong>of</strong> obesity. Herbalist suggested few herbal medicines such as aloe<br />
vera, Gymnema and panax ginseng will be more effective for obesity. Many more plants are<br />
there which have effect on obesity. Herbal medicine may be a vital tool to fight against<br />
obesity and prevent such diseases like hypertension, MI, diabetes Melitus before their<br />
occurance. Herbal medicines are much safer than modern medicines. Most <strong>of</strong> the herbal<br />
medicines have fewer side effects. Apart from that patients also lack <strong>of</strong> exercise which than<br />
leads to obesity. Whereas after the survey to the physiotherapist, they suggested that aerobic<br />
exercise will be effective in the management <strong>of</strong> obesity. Moreover, physical activity is<br />
lacking among Malaysians. 30 min/day <strong>of</strong> physical activity has a clear positive impact on<br />
cardiovascular health. Obesity is a serious problem, especially for its attendant cormobidity,<br />
and exercise is well suited to minimize several <strong>of</strong> these morbid processes in the masive obese<br />
patient. Hence we can conclude that herbal medicine and exercise together will be helpful in<br />
the management <strong>of</strong> obesity.<br />
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