Barbara C. Pence - Texas Tech University Health Sciences Center

NAME: Barbara C. Pence 

CURRICULUM VITAE 

ADDRESS: TTUHSC Office of Research, Room 2B106 

Texas Tech University Health Sciences Center 

Lubbock, Texas 79430 

Phone: (806) 743-2556 

FAX: (806) 743-2656 

e-mail: Barbara.Pence@ttuhsc.edu 

PERSONAL: 

Place of Birth: Plainfield, NJ 

Citizenship: United States Citizen 

EDUCATION: 

B.A. 

1977 

Microbiology, Chemistry (minor) 

Texas Tech University, Lubbock, Texas 

Barbara C. Pence Updated 

10/28/2008 

M.S. 

1979 

Microbiology (Genetic Toxicology) 

Texas Tech University 

Thesis Title: "A Mutagenesis Assay for the Colon Carcinogen 1,2dimethylhydrazine" 

Ph.D. 

1984 

Experimental Pathology, Nutrition 


Lubbock, Texas 

Dissertation Title: "A Multivariate Analysis of Dietary and Microbial Interactions in 

the Etiology of Colorectal Cancer" 

Health Organization Management (Certificate MBA Program) 

1993 


Lubbock, Texas 

Certificate in Health Organization Management 

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PROFESSIONAL CERTIFICATION: 

CCRP (Certified Clinical Research Professional), SoCRA, 2005-present 

Postdoctoral Training 

1986-87 

Carcinogenesis 

U.T. M.D. Anderson Cancer Center 

Science Park-Research Division, Smithville, Texas 

National Cancer Institute Training Workshop 

"Histopathobiology of Neoplasia", June 21-28, 1986, 

Keystone, Colorado 

Armed Forces Institute of Pathology Training course: "Comparative Pathology", 

April 4-26, 1989, Washington, DC 

New England Biolabs Molecular Biology and Biotechnology Summer Workshop, 

July 17-30, 1994, Smith College, Northampton, MA 

POSITIONS HELD: 

1977-1978 

Teaching Assistant in Microbiology: Department of Biological Sciences, Texas 

Tech University, Lubbock, Texas 

1978-79 

Research Assistant: Environmental Protection Agency Screening Program, 

Texas Epidemiological Studies, Department of Biological Sciences, Texas Tech 

University, Lubbock, Texas 

1979-1982 

Laboratory Technician III: Division of Comparative Pathology, Department of 

Pathology, Texas Tech University Health Sciences Center, Lubbock, Texas 

1983-1985 

Medical Research Technician III: Division of Vivarium Services, Texas Tech 

University Health Sciences Center, Lubbock, Texas 

1985-1986 

Postdoctoral Research Associate: Departments of Pathology and Vivarium 

Services, Texas Tech University Health Sciences Center, Lubbock, Texas 

1985-present 

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Assistant - Professor (Adjunct), Division of Food and Nutrition, Texas Tech 

University; Member of Graduate Faculty, 1987-present 

1986-1987 

Postdoctoral Fellow: Department of Experimental Carcinogenesis, U.T. M.D. 

Anderson Cancer Center, Science Park-Research Division, Smithville, Texas 

1987-1992 

Assistant Professor: Department of Pathology, Texas Tech University Health 

Sciences Center, Lubbock, Texas (TTUHSC) 

1987-1992 

Assistant Professor (Joint): Department of Biochemistry and Molecular Biology, 

TTUHSC 

1989-2008 

Member of Graduate Faculty, Department of Cell Biology and Biochemistry, 

TTUHSC 

1992 - tenure awarded 

1992-1996 

Associate Professor, Department of Pathology, TTUHSC 

1992-present 

Director of Research, Department of Pathology, TTUHSC 

1993-present 

Adjunct Associate Professor of Animal Science and Food Technology, Texas 

Tech University 

1995-present 

Joint Associate Professor of Radiology, TTUHSC 

1996-1999 

Assistant Director, Texas Tech University Institute for Biotechnology 

1996-present 

Professor of Pathology, TTUHSC 

1998-2008 

Associate Vice President for Research; 

Associate Dean for Research and the Graduate School 

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SCIENTIFIC AND PROFESSIONAL SOCIETIES: 

HONORS: 

American Association for Cancer Research 

American Society for Preventive Oncology 

American Association for Cancer Education 

American Institute of Nutrition 

Women in Cancer Research 

The Oxygen Society 


10/28/2008 

Travel Grant: to attend XIII International Congress of Nutrition in Brighton, 

England, American Institute of Nutrition, 1985, $850 

Postdoctoral Fellowship: National Research Service Award, Training Grant # CA- 

09480 (T32), National Cancer Institute, 1986-88 

Award for Outstanding Publication, Denver Wildlife Research Center, 1983 

Soroptimist Club Mentor/Mentee Program: Mentor, 1991 

Cited in Who's Who in Science and Engineering 1st Edition, 1992 - present. 

Cited in World Who's Who of Women, 12th Edition, 1993 - present. 

“Scientist of the Year”, ARCS, Lubbock, Texas Chapter, 1998. 

Member, Metabolic Pathology Study Section, National Cancer Institute, 1993- 

1997. 

Member, Board of Directors, Texas Society for Biomedical Research, 1998present 

Member, Nutritional Implementation Committee, Division of Cancer Prevention, 

National Cancer Institute, NIH, 1998-2000. 

Member, National Cancer Institute Subcommittee E, 2002-present. 

Member, National Toxicology Program Board of Scientific Counselors, 2002- 

2005 

Distinguished Alumna, College of Human Sciences, Texas Tech University, 2002 

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Recipient: Marsha Sharp “Making a Difference for Women Award‟, from 

Soroptimist International, April 21, 2004. 

Member, Physicians Oncology Education Program Steering Committee, Texas 

Medical Association, 2005-present 

COMMITTEES: 

Texas Tech University Health Sciences Center: 

Founding Member, TTUHSC Institutional Biohazards Committee, 1988-1998; 

Chair, 1988-90 

Member, TTUHSC Faculty Appointments Committee, 1988-1991, 1995-1998 

Member, TTUHSC Admissions Committee, 1988-present 

Member, Research Strategic Planning Committee, TTUHSC, 1989 

Member, TTUHSC Educational Policy Committee, 1989-1992; 1993-present; 

Chair, 1990-91 

Member, TTUHSC Faculty Development Leave Committee, 1989 

Member, TTUHSC Grading and Promotions Committee, 1990-1993; Chair, 

1991-92 

Member, TTUHSC Faculty Executive Council, 1991-1994 

Member, TTUHSC Faculty Research Council, 1991-1994, 1995-1996 

Member, TTUHSC Biochemistry Chair Search Committee, 1991 

University Medical Center: 

Member, University Medical Center Cancer Committee, 1996-1998; member 

Cancer Audit Sub-Committee, 1991-1994 

Member, Joint Strategic Planning Task Force, 2000 

National Organizations: 

Vice-Chairperson, Planning Committee for 1991 FASEB Conference "Molecular 

Nutrition, Gene Expression and Carcinogenesis" 

Member, Membership Committee, American Association for Cancer Research, 

1992-93, 1995-1996 

Member, Program Committee, American Association for Cancer Research, 

1994-95 

Member, Program Committee, Women in Cancer Research, 1995-1996 

Co-Chair, American Institute for Cancer Research Workshop “Diet, Nutrition and 

Cancer Prevention: Research Opportunities, Approaches and Pitfalls”, 1995 

Co-Chair, American Association for Cancer Research Workshop “Nutrition and 

Cancer Prevention”, annual meeting, 1996 

RESEARCH GRANTS AND SUPPORT: 

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Research Assistantship: Texas Epidemiologic Studies Project, Cooperative 

Agreement CR806904-01, Environmental Protection Agency, 1978-79 

Grant: "Multiple Dietary Factors in the Promotion or Inhibition of Colorectal 

Cancer", Institute for Nutritional Sciences, Texas Tech University, 1983-84, 

$7,450 

Grant: "Interactions of Dietary Factors as Modifiers of Colon Carcinogenesis", 

College of Home Economics Research Institute, Texas Tech University, 1983- 

84, $4000 

Grant: "Effects of Calcium/Vitamin D Supplementation on Colon Carcinogenesis 

in Rats", Institute for Nutritional Sciences, Texas Tech University, 1985-86, 

$4780 

Grant: "Development of a Colon Multistage Carcinogenesis Model", Texas Tech 

University Health Sciences Center Seed Research Grant Program, 1987-88, 

$5865 

Grant: "Reactive Oxygen Species and Selenium Deficiency: Effects on 

Metabolism of 1,2-Dimethylhydrazine", Institute for Nutritional Sciences, Texas 

Tech University and Health Sciences Center, 1987-88, $5000 

Grant: "Colon Multistage Model: Validation", Texas Tech University Health 

Sciences Center Seed Research Grant Program, 1988-89, $4000 

Grant: "Beef Tallow and Oxidative Stress in Colon Carcinogenesis", National 

Livestock and Meat Board, 1988-89, $19,150 

Grant: "Modulation of Murine Multistage Skin Carcinogenesis by Vitamin D 3 ", 

Institute for Nutritional Sciences, Texas Tech University and Health Sciences 

Center, 1988-89, $5600 

Medical Student Summer Research Fellowship, TTUHSC, Summer, 1989 for R. 

Stephen Lawlis, $1500 

Grant: Dietary Calcium and Multistage Skin Carcinogenesis", TTUHSC Seed 

Research Grant, 1989-90, $6000 

Grant: Beef Tallow and Oxidative Stress in Colon Carcinogenesis", Institute for 

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Nutritional Sciences, Texas Tech University and Health Sciences Center, 

Student fellowship, 1990, $6000. 

Grant: Visiting Professor in Nutrition Program, National Dairy Council, March 1-2, 

1990, $1500. 

Grant: "Beef Tallow versus Polyunsaturates: Production of Oxidant Damage 

Related to Colon Carcinogenesis", 1990, National Livestock and Meat Board, 

$22,909 

Grant: "Antioxidant Status: Relevance to Colon Carcinogenesis and Tumor 

Promotion by Type of Dietary Fat", summer 1990, Institute for Nutritional 

Sciences, Texas Tech University and Health Sciences Center, $2500 

Grant: "Beef Tallow and Oxidative Stress in Colon Carcinogenesis", summer 

1990, Institute for Nutritional Sciences, Texas Tech University and Health 

Sciences Center, $600 

Grant: "Antioxidant Status: Relevance to Colon Carcinogenesis and Tumor 

Promotion by Type of Dietary Fat", Institute for Nutritional Sciences, Texas Tech 

University and Health Sciences Center, 1990-91, $7500 

Grant: "Calcium Inhibition of Colon Cancer Progression", National Institutes of 

Health # CA52006-01A1, 1/1/91 - 12/31/93, $267,517 

Grant: "Antioxidant Defenses During Colon Carcinogenesis: Effects of Beef 

Tallow Versus Polyunsaturates", National Live Stock and Meat Board, 1/1/91 - 

12/31/91, $33,424 

Grant: "Elemental Versus Dairy Product Calcium: Implications for Colon Cancer 

Prevention", National Dairy Council, 1/1/91 - 12/31/93, $133,080 

Grant: "Colon, Prostate and Cervical Cancer Control Program for Rural West 

Texas", Texas Cancer Council, 3/1/92 - 8/31/92, $25,000. 

Grant: "Participating Institution: Texas Community Oncology Network", UT MD 

Anderson Cancer Center, Co-Investigator, 7/1/92 - 3/31/94, $248,235. 

Grant: "West Texas Coalition for Cancer Control, Public Health Region 3", Texas 

Cancer Council, 9/1/92 - 8/31/93, $100,000. 


Cancer Council, Co-Investigator, 9/1/92 - 8/31/93, $60,000. 

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Grant: "Lean Beef versus Total Fat in Colon Carcinogenesis", American Institute 

for Cancer Research, 1/1/93 - 12/31/94, $110,000. 

Grant: "HealthNet", Physicians's Oncology Education Program of the Texas 

Medical Association, 4/1/93 - 8/31/93, $15,000. 


Cancer Council, 9/1/93 - 8/31/94, $89,000. 

Grant: “CATCHUM Project”, University of Texas Medical Branch at Galveston”, 

4/1/93 -8/31/95, $15,000. 

Grant: “West Texas Coalition for Cancer Control, Public Health Regions 9 and 

10”, Texas Cancer Council, 9/1/94 - 8/31/95, $101,689. 

Travel grant: To attend the 16th International Cancer Congress in New Delhi, 

India, October 30 - November 5, 1994, $3,000. 

Grant: “Meat Cooking Methods and Colon Carcinogenesis”, American Institute 

for Cancer Research, 1/1/95 - 12/31/96, $110,000. 

Grant: “Heme Iron from Beef and its Role in Colon Carcinogenesis”, Texas Tech 

University Institute for Nutritional Sciences, 9/1/94 - 8/31/95, $10,000, PI: Dr. 

Mark Miller. 

Grant: West Texas Coalition Against Cancer”, Texas Cancer Council, 6/1/95 - 

8/31/95, $300,000, PI: Dr. Glen Roberson. 

Grant:Mentor, Summer Medical Student Research Fellowship, 1995, $1500. 

Grant: “West Texas Mammography Program”, Texas Cancer Council, 9/1/95 - 

8/31/96, $184,846. 

Grant: “The CATCHUM Project”, National Cancer Institute 1 R25 CA65618-01, 

4/1/95 3/31/98, subcontractee, PI: Billy U. Philips, $21,500 

Grant: “Evaluation of the Roles of Antioxidant Nutrients in the Protection of 

Macromolecules, and Regulation of Apoptosis Following UVB Irradiation of 

Keratinocytes in Culture”, Institute for Nutritional Sciences, TTU, 9/1/95 - 

8/31/96, $10,000 

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Grant: “Inhibition of Skin Cancer Growth by Selenium Compounds, E”.A. Franklin 

Endowment Fund, 1/1/96 - 12/31/97, $50,000 

Grant: “Cooked Meat Mutagens and Increased Risk for Mammary Cancer”, 

Texas Tech University Institute for Nutritional Sciences, 9/1/96 - 8/31/97, 

$10,000 


8/31/97, $194,539. 


8/31/98, $194,991. 

Grant: “Selenium: Antioxidant or Prooxidant Mechanism”, National Cancer 

Institute, R01 CA76675, 1/1/98 - 11/30/03, $739,785. 

Grant: “Development of a Genetic Counseling Service for Genetic Testing for 

Breast Cancer”, Lubbock Area Chapter of the Susan G. Komen Breast Cancer 

Foundation, 1/1/98 – 12/31/98, $10,000. 

Grant: “The CATCHUM Project”, National Cancer Institute 2 R25 CA65618-05, 

4/1/98-3/31/03, B. Pence, subcontractee, PI: Billy U. Philips, $75,000. 

Grant: “Genetic Effects of Pesticide Exposure in the Aral Sea Region”, NATO, 

5/1/00 – 4/30/02, B. Pence, collaborator, PI: Spencer Wells, $14,200. 

Grant: Neely Treadwell Cancer Investigator Award, Southwest Cancer Center, 

11/1/03 –5/31/04, $15,000 

Grant: “The CATCHUM Project”, National Cancer Institute 2 R25 CA65618- 

09/26/03-10/1/08, B. Pence, subcontractee, PI: Billy U. Philips, $15,000. 

Grant: “West Texas Rural EXPORT Center”, (National Center for Minority Health 

and Health Disparities (NIH) 1 R24 MD0001097-01, 08/31/05-08/31/08. B. 

Pence, Director of Administrative and Research Cores, PI: Patti Patterson, $1, 

225,125. 

Grant: “Bridging the Gap: A Patient-Centered Curriculum for Cultural 

Competence”, National Heart, Lung, and Blood Institute, 1 K07 HL81467-01A1, 

09/30/06-08/31/11. B. Pence, Co-Investigator, PI: Lynn Bickley, $640,725. 

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Grant: “GTP and Tai Chi for Bone Health: A Pilot Study”, National Center for 

Complementary and Alternative Medicine (NIH), 1 R21 AT003735-01A1, 

06/01/07–05/31/09. B. Pence, consultant, PI: Chwan-Li Shen, $445,500. 

RESEARCH INTERESTS: 

Cancer Chemoprevention 

Chemical Carcinogenesis 

Nutrition/Disease Interactions 

Toxicology 

Oxygen Radical Pathogenesis 

Heterocyclic Amine Carcinogenesis 

Selenium 

JOURNAL REVIEWER: 

Gastroenterology 

Cancer Research 

Carcinogenesis 

Nutrition and Cancer 

Cancer Letters 

Journal of Investigative Dermatology 

Journal of the National Cancer Institute 

Lipids 

Journal of Nutritional Biochemistry 

The Cancer Journal 

Archives of Biochemistry and Biophysics 

Journal of Wildlife Diseases 

Academic Medicine 

GRANT REVIEWER: 

*March of Dimes Grants Program: 1989, 1991 

*AdHoc Member, Scientific Advisory Board, National Live Stock and Meat Board, 

1991 

*NIH, National Cancer Institute, special outside reviewer, Metabolic Pathology 

Study Section: 1991, 1992 

*NSF, ASEND grant program - North Dakota, 1991, 1992 

*Dept. of Veterans Affairs, Veterans Health Services and Research 

Administration: 1992 

*NIH, National Cancer Institute, Ad Hoc Member, Metabolic Pathology Study 

Section: 1992-1993 

*NIH, National Institute of General Medical Sciences, outside reviewer, 1992 

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*USDA Special Grants Program for Tropical and Subtropical Agriculture, 1993 

*USDA Human Nutrition Grants Program, 1993, 1994-present 

*National Live Stock and Meat Board, grants review panel, 1993 

*NIH, regular member, Metabolic Pathology Study Section, 1993-1997 

*NCI, Special Review Committees for numerous RFA's, SEP‟s and site visits, 

1993- present 

*U.S. Army Medical Research and Development Command, Special Reviewer 

for breast cancer research program, 1994. 

*Ad Hoc Reviewer, American Institute for Cancer Research grants program, 

1995 

*Member, scientific review panel, Susan G. Komen Foundation research grants 

program, 1995 

*Member, American Institute for Cancer Research Review Panel I, 1996-present 

*Member, National Dairy Council Review Team, Dartmouth College Dairy 

Research Institute for Colon Cancer, 1995 

*Member, US Army Medical Research and Development Command review panel 

for prostate cancer research program, 1998-2001 

*Ad-hoc Member, National Cancer Institute Subcommittee E, 2001 (reviews 

Center Grants and Program Project grants) 

*Member, NIH National Cancer Institute Subcommittee E, 2002-present; Chair 

2006-present 

*Member, Board of Scientific Counselors, National Toxicology Program, 2002- 

2005 

INVITED SEMINARS: 

U.T. M.D. Anderson Cancer Center, Houston, Texas, Sept. 12, 1985, "Multiple 

Dietary Factors and Etiology of Colon Cancer" 

University of Arizona Cancer Center, Tucson, Arizona, Oct. 8, 1985, "Multiple 

Dietary Factors in the Etiology of Colorectal Cancer" 

Oklahoma State University, Stillwater, Oklahoma, Satellite Teleconference, 

"Calcium, Osteoporosis and Beyond" aired in February 1986, and "The Diet and 

Cancer Link" aired in December 1986 

University of Texas at Austin, Austin, Texas, February 23, 1987, 

"Chemoprevention of Cancer: Role of Diet" as part of seminar series, "Nutrition, 

Immunology and Cancer" 

Fourth Texas Carcinogenesis Meeting, Smithville, Texas, October 3, 1987, 

"Calcium or Vitamin D Inhibition of Colon Carcinogenesis Promoted with Dietary 

Fat" 

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Panel Discussion, National Dairy Council, Chicago, Illinois, April 13, 1988, 

Nutrition Research Conference, "Update on Dietary Calcium and Cancer" 

Symposium speaker, Federation of American Societies for Experimental Biology 

Summer Research Conference: "Nutrients and Gene Expression in 

Carcinogenesis", July 30-August 4, 1989, Copper Mountain, Colorado 

Invited Seminar Speaker, University of Texas at El Paso, Department of Biology, 

"Oxygen Radicals in Tumor Promotion", October 20, 1989 

Symposium speaker, "Nutrition and Cancer Prevention Conference", November 

9, 1989, Austin, Texas, sponsored by the Austin Dietetic Association and the 

Texas Department of Health. 

Invited participant and speaker, National Cancer Institute-sponsored workshop 

on "Calcium, Vitamin D and Colon Cancer", Vail, CO, July 8-10, 1990. 

Invited speaker, "Partners in Prevention", American Cancer Society-sponsored 

symposium, October 11, 1990, Houston, Texas. 

Invited speaker, "Micronutrients and Colorectal Cancer Risk: Implications for 

Chemoprevention", 5th International Symposium on Colorectal Cancer, Turin, 

Italy, September 24-26, 1991. 

Invited speaker, "Calcium and Gastrointestinal Cancer", Dairy Council of Arizona 

Nutrition Conference "Targeting Trends in Nutrition and Cancer", Tempe, AZ, 

October 4, 1991. 

Invited seminar speaker, "Nutritional Modulation of Detoxification Systems", to 

Faculty of Toxicology, Texas A & M University, October 28, 1991. 

Invited speaker, "PKC: Implications for Colon Carcinogenesis", to Department of 

Gastrointestinal Oncology, Univ. of Texas M.D. Anderson Cancer Center, 

January 15, 1992. 

Invited speaker, "Role of Calcium in Colon Cancer Prevention: Experimental and 

Clinical Studies", at conference "Towards Reducing the Incidence of Colorectal 

Cancer: The Role of Inheritance and Diet", February 18, 1993, Aukland, New 

Zealand. 

Invited speaker, "National Dairy Board Annual Research Conference", Ashland, 

New Hampshire, May 4-5, 1993. 

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Panel Discussant, "Diet and Cancer Prevention", Rutgers University, June 11, 

1993. 

Invited speaker, "Dietary Effects in Animal Models for Colon Cancer", M.D. 

Anderson Annual Clinical Conference on the Advances in the Biology and 

Therapy of Colorectal Cancer, November 6, 1993. 

Invited seminar, “Chemoprevention of Colon Cancer with Dietary Calcium: 

Animal Studies”, University of Texas Southwestern Medical School, December 2, 

1993. 

Invited seminar, “UV-Induced Damage in Murine Epidermis: Role of Antioxidant 

Enzymes”, Oklahoma Medical Research Foundation, December 9, 1993. 

Symposium speaker, “Prevention of Colorectal Cancer: Dietary 

Recommendations and Clinical Trials”, POEP conference, Colorectal Cancer: 

Detection, Prevention, Treatment, Lubbock, Texas, June 18, 1994. 

Invited speaker: “Local Health Services Research using Tumor Registry Data”, 

Texas Tumor Registrars State Meeting, Lubbock, Texas, October 27, 1994. 

Symposium speaker, “Modulation of Oxidative Damage to DNA by Sodium 

Selenite via the Mechanism of Apoptosis”, Sixth International Symposium on 

Selenium in Biology and Medicine, Beijing, China, August 20, 1996. 

Invited speaker, “Is Well-cooked Meat a Cause of Human Cancer?”, Friday 

Seminar Series, University of Texas M.D. Anderson Cancer Center, September 

20, 1996. 

Invited speaker, “West Texas Cancer Prevention Partnership”, University of 

Texas System Texas-Mexican Border Health Symposium, South Padre Island, 

Texas, October 25, 1996. 

Invited speaker, “Red Meat, Heterocyclic Amines, and Human Cancer”, 

University of South Carolina Cancer Center, October 23, 1998. 

Invited speaker, “Nutrition: The Forgotten Ingredient in Cancer Care”, Taylor- 

Jones-Haskell County Medical Society, sponsored by POEP, Abilene, TX, May 

18, 2000. 

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Invited speaker: “Nutrition and Cancer Therapy: The Good, the Bad and the 

Ugly”, presented at POEP symposium at TMA Annual Meeting, San Antonio, TX, 

May 27, 2000. 

Invited speaker:, “Is well-cooked meat a cause of human cancer?”, presented at 

workshop “What‟s new in Diet and Cancer Prevention?”, presented at Annual 

Meeting of American Dietetic Association, Denver, CO, Oct. 16, 2000. 

Invited speaker: “Nutrition and the Cancer Patient”, presented at Texas Oncology 

Nurses Association, Dallas, TX, April 27, 2001. 

Keynote speaker: “Nutrition and Cancer: From Prevention to Survivorship”, 45 th 

Annual Nutrition and Food Service Seminar, University of Texas, Austin, TX, 

March 21, 2002. 

Invited speaker: “Cancer – What Primary Care Physicians Need to Know”, 

presented at POEP symposium at TMA Annual meeting, Dallas, TX, April 20, 

2002. 

Invited speaker: “Nutrition and Cancer: From Prevention to Survivorship”, 

presented at the Lubbock, Crosby, Garza County Medical Society meeting, May 

8, 2004. 

Invited speaker: “Nutrition and Cancer: From Prevention to Survivorship”, 

presented at the Lubbock chapter of the Susan G. Komen Foundation, May 8, 

2004. 

Invited speaker: “Nutrition and Cancer”, UMC Southwest Cancer Research and 

Treatment Center „Well-Informed‟ public lecture, presented August 24, 2004. 

Invited speaker: “Symposium 2005: IRB Best Practices”, UT Southwestern, May 

11-12, 2005. 

Presenter: “Obesity and Cancer”, CNNT Cancer Survivors‟ Workshop, ACS, 

Lubbock, TX, August 28, 2006. 

Invited Participant: “Eliminating Disparities in Clinical Trials (EDICT): Formulating 

Policies” Roundtable, Houston, TX, September 6-8, 2006. 

Invited speaker: “Clinical Research: What comes after the guinea pigs?” 

Southwest Cancer Center Public Lecture, Lubbock, TX, November 2, 2006. 

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Roundtable presentation at AAMC GREAT meeting on training graduate 

students for translational and clinical research, April 27, 2007 

Invited Presentation to SACHRP (Secretary‟s Advisory Committee on Human 

Research Protections): “Eliminating Disparities in Clinical Trials” on July 31, 

2007, Washington, DC 

Panel discussion/presentation: “Eliminating Disparities: The Scientific 

Perspective” at PRIM&R meeting, December 4, 2007 

National Press Conference: “EDICT Recommendations for Clinical Trials”, 

National Press Club, Washington DC, April 1, 2008. 

ABSTRACTS: 

1. Felkner, I.C., M.J. Wargovich and B.C. Wells. 1981. Colon cancer induced in rats by 

1,2-dimethylhydrazine: parallel mutagenesis and enzymology monitored by a 

Bacillus subtilis detector system. In: Abstracts of the January 1981 Workshop, 

"The Large Bowel Cancer Program: Its Achievements and Future Investigation". 

2. Wells, B.C., M.J. Wargovich and I.C. Felkner. 1981. Characterization of interactions 

affecting mutagenic activity of the colon carcinogen, 1,2-dimethylhydrazine. 

Annual Meeting of the American Society for Microbiology, Dallas, Texas. 

3. Pence, D.B., B.C. Wells and L. Windberg. 1981. Sarcoptic mange in south Texas 

coyotes. Annual Meeting of the Wildlife Disease Association, Laramie, Wyoming. 

4. Pence, D.B. and B.C. Wells. 1982. Epizootiology of sarcoptic mange in south 

Texas coyotes. Fifth International Congress of Parasitology, Toronto, Canada 

(Abstracts, In: Mol. Biochem. Parasitol. Suppl., p. 570). 

5. Pence, B.C. and F. Buddingh. 1984. Dietary selenium deficiency and 1,2dimethylhydrazine-induced 

colon cancer. Fed. Proc. 43: 794. 

6. Pence, B.C. and F. Buddingh. 1984. Effects of selenium deficiency on 1,2dimethylhydrazine-induced 

colon cancer in rats. Third International Symposium 

on Selenium in Biology and Medicine, Beijing, China. 

7. Pence, B.C. 1985. Dietary cholesterol effects on fecal levels of Bacteroides fragilis 

group organisms. Annual Meeting of the American Society for Microbiology, Las 

Vegas, Nevada. 

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8. Pence, B.C., S.P. Yang and F. Buddingh. 1985. Multiple dietary interactions in the 

promotion of colon cancer in rats. Fed. Proc. 44: 1499. 

9. Pence, B.C., F. Buddingh and S.P. Yang. 1985. Enhancement of 1,2dimethylhydrazine 

tumorigenesis by dietary cholesterol, beef fat and indole-3carbinol. 

Proc. American Association for Cancer Research 26: 124. 

10. Pence, B.C., S.P. Yang and F. Buddingh. 1985. A model for the study of the 

effects of complex dietary interactions on carcinogenesis. Abstracts, XIII 

International Congress of Nutrition, Brighton, England 

11. Buddingh, F. and B.C. Pence. 1985. Enhancement of 1,2-dimethylhydrazine 

tumorigenesis by dietary cholesterol, beef fat and indole-3-carbinol. Annual 

Meeting of the Texas Branch of the American Association for Laboratory Animal 

Science, Arlington, Texas. 

12. Pence, B.C. and F. Buddingh. 1986. Dietary effects on lipid peroxides and uric 

acid in rat serum. Fed. Proc. 45: 1076. 

13. Pence, B.C., S.C. Buessow, M.T. Yang, S.P. Yang and F. Buddingh. 1986. Effect 

of selenium and molybdenum supplementation on K562 erythroleukemia cells in 

culture. Fifth Joint Meeting of the American Institute of Nutrition, American 

Society for Clinical Nutrition and the Canadian Society for Nutritional Sciences, 

Davis, California. J. Nutr. 116: xxxi. 

14. Pence, B.C. and F. Buddingh. 1987. Inhibition of dietary fat promotion of colon 

carcinogenesis by supplemental calcium or vitamin D. Proc. American 

Association for Cancer Research 28: 154. 

15. Reiners, J.J.Jr. and B.C. Pence. 1987. 12-O-Tetradecanoylphorbol-13-acetatedependent 

induction of xanthine dehydrogenase and conversion to xanthine 

oxidase in murine epidermis. Proc. American Association for Cancer Research 

28: 160. 

16. Pence, B.C. 1989. Reactive oxygen species and selenium deficiency: toxic effects 

of 1,2-dimethylhydrazine. FASEB J. 3: A779. 

17. Pence, B.C. and M.F. Naylor. 1989. Effects of single-dose ultraviolet light on 

superoxide dismutase, catalase, glutathione peroxidase and xanthine oxidase in 

Skh:HR-1 mouse epidermis. Proc. American Association for Cancer Research 30: 

200. 

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18. Pence, B.C., Demick, D.S. and F. Buddingh. 1989. Effective control of Myobia 

spp. in laboratory mice with chlorpyrifos (Dursban TM ). Annual Meeting of Texas 

Branch of the American Association for Laboratory Animal Science, Fort Worth, 

Texas. 

19. Kuratko, C.N. and B.C. Pence. 1989. The effect of different dietary fats on oxygen 

radical detoxication in rat colon. Annual Meeting of the American Dietetic 

Association, Kansas City, Missouri. J. Amer. Dietetic Assoc. 89: A-59, 1989. 

20. Kuratko, C.N. and B.C. Pence. 1990. Effect of different dietary fats and 1,2dimethylhydrazine 

on oxygen radical detoxification in rat colon. FASEB J. 4: 

A666. 

21. Pence, B.C., Lawlis, R.S. and C.N. Kuratko. 1990. Effect of dietary vitamin D 3 on 

mouse skin tumor promotion. Proc. Amer. Assoc. for Cancer Res. 31: 143 

(A850). 

22. Pence, B.C., Kuratko, C.N. and S.-Y. Tsai. 1990. Dietary fat effects on antioxidant 

status of rat colon: implications for carcinogenesis. To be presented at "Oxidative 

Damage and Repair", November 14-20, Pasadena, CA. Free. Rad. Biol. Med. 9 

Suppl.: 164. 

23. Tsai, S.-Y., Richard, B.C. and B.C. Pence. 1991. Effects of dietary fat on hepatic 

microsomal metabolism of 1,2-dimethylhydrazine. FASEB J. 5: A926. 

24. Kuratko, C.N., Tsai, S.-Y. and B.C. Pence. 1991. Effects of dietary fat and 1,2dimethylhydrazine 

on hepatic microsomal lipid peroxidation. FASEB J. 5: A1281. 

25. Pence, B.C. and G.S. Cameron. 1991. Effects of multiple applications of tumor 

promoters and ultraviolet radiation on epidermal proliferation and antioxidant 

status. Proc. Amer. Assoc. for Cancer Res. 32: 150 . 

26. Pence. B.C. 1991. Do dietary fats promote colon cancer by inducing oxidative 

stress? NIH Workshop: Cellular and Molecular Targets for Chemoprevention, 

March 16-19, 1991, Charleston, SC. 

27. Pence, B.C. 1991. Micronutrients and colorectal cancer risk: implications for 

chemoprevention. Proc. 5th International Symposium on Colorectal Cancer. 

Torino, Italy, p. 54. 

28. L.S. Binder, J. Brown III, E.J. Wheeler, J.A. Chappell, T. McMahon, P. Doris, B. 

Pence, R. Rolfe, P. Castiglia, R. Elizondo, R. Brands, A. Reynolds, D. Mahr, S. 

17


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Reding, J. Barber, and P. Duarte. 1991. The W.K. Kellogg Foundation's 

community partnership with health professions education (CP/HPE): The Texas 

Tech model emerges. Proc. Assoc. American Medical Colleges Annual Meeting. 

29. Pence, B.C., Zhao, C. and S. Hunter. 1992. Elemental versus dairy calcium: 

effects on colonic protein kinase C and ornithine decarboxylase. FASEB J. 6: 

A1494. 

30. Tsai, S.-Y., Dunn, D.M. and B.C. Pence. 1992. Colonic antioxidant status during 

dimethylhydrazine carcinogenesis: effects of type and amount of dietary fat. 

FASEB J. 6: A1395. 

31. Pence, B.C., Dunn, D.M., Zhao, C. Hunter, S. and M.J. Wargovich. 1992. 

Modulation of rat colonic protein kinase C and ornithine decarboxylase by dietary 

calcium. Proc. Amer. Assoc. for Cancer Res. 33: 130 (779). 

32. Pence, B.C. 1993. Role of calcium in colon cancer prevention: experimental and 

clinical studies. Presented at conference, "Towards Reducing the Incidence of 

Colorectal Cancer: The Role of Inheritance and Diet", Aukland, New Zealand, 

Feb. 15-19, 1993. 

33. Tsai, S.-Y. and B.C. Pence. 1993. Effect of type and amount of dietary lipid on 

colonic nuclear aberrations during colon carcinogenesis. FASEB J. 7:A174. 

34. Delver, E. and B.C. Pence. 1993. Effects of dietary selenium level on UV-induced 

skin cancer and epidermal antioxidant status. FASEB J. 7:A290. 

35. Pence, B.C., Zhao, C., Hunter, S. and M.J. Wargovich. 1993. 

Compartmentalization of calcium, free fatty acids and bile acids in rats fed cholic 

acid and CaCO 3 . Gastroenterology 104:A440. 

36. Pence, B.C., Dunn, D.M., Zhao, C., Landers, M. and M.J. Wargovich. 1994. 

Experimental chemoprevention of colon carcinogenesis by combined calcium and 

aspirin. Proc. Amer. Assoc. Cancer Res. 35: 624. 

37. Pence, B.C., Dunn, D.M., Zhao, C. and M. Landers. 1994. Elemental vs. dairy 

product calcium in experimental colon cancer prevention. FASEB J. 8:A426. 

38. Zhao, C., Landers, M., Butler, M., Miller, M. and B.C. Pence. 1994. Effects of beef 

protein and fat source on serum iron status in rats. FASEB J. 8:A721. 

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39. Pence, B.C., Zhao, C., Landers, M. and M.J. Wargovich. 1994. Modulation of 

colonic protein kinase C by dietary bile acids, calcium carbonate, and aspirin. 

Proc. XVI Internatl.Cancer Congress, Delhi, India. 

40. Ronaghan, C.A. and B.C. Pence. 1994. Strategies for cancer control program 

implementation in rural regions. Proc. XVI Internatl. Cancer Congress, Delhi, 

India. 

41. Pence, B.C., Dunn, D.M., Zhao, C., Landers, M. and M.J. Wargovich. 1994. 

Validation of intermediate biomarkers during experimental colon carcinogenesis in 

rats. Gastroenterology, 106, A427. 

42. Landers, M., Dunn, D.M., Zhao, C., B.C. Pence and M.J. Wargovich. 1994. 

Promotional effects of lactose feeding on small bowel tumorigenesis in an 

experimental animal model of colon carcinogenesis, Gastroenterology, 106, A407. 

43. Butler, M.J., Miller, M.F. and B.C. Pence. 1994. Lack of colon promoting 

carcinogenesis by beef in the rat model. Annual Meeting of the American Meat 

Science Association. 

44. Kuratko, C.N. and B.C. Pence. 1994. Dietary lipid and iron modify normal colonic 

mucosa without affecting phospholipase A2 activity. American Institute for Cancer 

Research meeting, Washington, D.C. 

45. Pence, B.C., Butler, M.J., Dunn, D.M. and M.F. Miller. 1994. Non-promoting effects 

of lean beef in the rat colon carcinogenesis model. American Institute for Cancer 

Research meeting, Washington, D.C. 

46. Kuratko, C.N. and B.C. Pence. 1995. Fatty acid composition of colon mucosa is 

altered by dietary lipid and iron without affecting phospholipase A2 activity. Proc. 

Amer. Assoc. Cancer Res. 36, 115 (#682). 

47. Stewart, M.S., Cameron, G.S., Harris, B.D. and B.C. Pence. 1995. Modulation of 

UVB-induced oxidative damage to DNA in murine keratinocytes by sodium 

selenite. Proc. Amer. Assoc. Cancer Res., 36, 113 (# 669). 

48. Stewart, M.S., Cameron, G.S. and B.C. Pence. 1995. Modulation of ultraviolet B 

light-induced oxidative damage by vitamins C and E. FASEB J. 9: A988 (#5736). 

49. Walsh, L.P. and B.C. Pence. 1995. Induction of apoptosis by sodium selenite in 

human colonic carcinoma cells. Gastroenterology 108, A550. 

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50. Philips, B.U. Jr., M. Becker, J.R. Bowling, E. Buck, C.O. Freytes, J.B. Green, L. Kirk, 

B.C. Pence, J. Shores and A. Weinberg. 1995. Impact evaluation drives strategic 

planning in cancer education: The Texas consortium. Annual meeting, American 

Association for Cancer Education. 

51. Philips, B.U. Jr., J.B. Battles, M. Becker, J.R. Bowling, C. Browne, E. Buck, M. 

Calloway, C.O. Freytes, J.B. Green, L. Kirk, B.C. Pence, J. Shores, J. Sprankell 

and A. Weinberg. 1995. OSCE‟s: A teaching tool in cancer prevention, detection 

and control. Annual meeting, American Association for Cancer Education. 

52. Becker, M., Battles, J.B., Bowling, J.R., Brown, C., Buck, E., Callaway, M., Freytes, 

C.O., Green, J.B., Kirk, L., Pence, B.C., Philips, B.U., Shores, J., Sprankell, J., 

and Weinberg, A. 1995. A template for longitudinal clinical performance 

assessment. Annual meeting of Generalists in Medical Education, Washington 

DC. 

53. Battles, J.B., Becker, M., Bowling, J.R., Brown, C., Buck, E., Callaway, M., Freytes, 

C.O., Green, J.B., Kirk, L., Pence, B.C., Philips, B.U., Shores, J., Sprankell, J., 

and Weinberg, A. 1996. Intra-institutional multi-level OSCE stations for screening 

and detection of cancer. Presented at international OSCE meeting at Maastricht, 

the Netherlands. 

54. Stewart. M.S. and Pence, B.C. 1996. Modulation of UVB-induced oxidative 

damage to DNA of murine keratinocytes by sodium selenite: lack of effect on 

repair. Proc. Amer. Assoc. Cancer Res. 37: 143 (#988). 

55. Stewart, M., Dixon, M. and Pence, B.C. 1996. Changes in activity of antioxidant 

enzymes in mouse keratinocytes following UVB irradiation. FASEB J.10: A740 

(#4281). 

56. Pence, B.C., Landers, M. and Walsh, L.P. 1996. Induction of heterocyclic amine 

metabolism in rats by diets containing well-browned beef and a high fat content. 

Gastroenterology 109, A575. 

57. Pence, B.C., Stewart, M., Walsh, L. and Cameron, G. 1996. Modulation of oxidative 

damage to DNA by sodium selenite via the mechanism of apoptosis. Proceedings 

of the Sixth International Symposium on Selenium in Biology and Medicine, 

Beijing, China, August 18-23. 

58. Pence, B.C., Shen, C.-L., Landers, M. and Walsh, L.P. 1996. Induction of 

heterocyclic amine metabolism in rats by diets containing well-browned beef and a 

high fat content. Proceedings of the Annual Research Conference of the 

American Institute for Cancer Research, Washington, D.C., August 29-30. 

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59. Morell, S.R., Battles, J.B., Becker, M., Bowling, J.R., Buck, E., Freytes, C.O., 

Green, J.B., Laufman, L., Pence, B.C., Shores, J., Weinberg, A. and Philips, B.U. 

1996. A template for the creation of an educational Internet Site. J. Cancer Educ. 

1996, 11:26 (#64). 

60. Stewart, M., Spallholz, J., Neldner, K., and Pence, B.C. Disparate protective effects 

of selenite, selenocystamine, and selenomethionine in keratinocytes. 

Experimental Skin Carcinogenesis Conference, Bastrop, Texas, October 28-31, 

1996. 

61. Stewart, M.S. and Pence, B.C. 1997. Selenium compounds differ in their abilities to 

exert prooxidant effects and induce apoptosis in UVB-exposed keratinocytes. 

Proc. Amer. Assoc. Cancer Res.38: 79 (#529). 

62. Davis, R.L., Spallholz, J.E., and Pence, B.C. 1997. Copper inhibits seleniteinduced 

cytotoxicity in human colonic carcinoma cells (HT29). FASEB J. 11: A403 

(#2333). 

63. Shen, C.-L., Purewal, M., San Francisco, S. and Pence, B.C. 1997. Absence of 

PhIP adducts and p53 mutations in rats fed a cooked beef diet containing high 

levels of heterocyclic amines. FASEB J. 11: A572 (#3328). 

64. Stewart, M.S., Spallholz, J.E., Neldner, K. and Pence, B.C. 1997. Cytotoxicity of 

selenium compounds to cultured normal primary human keratinocytes and 

squamous cell carcinoma cells. FASEB J. 11: A403 (#2332). 

65. Kuratko, C., Brinlee, R. and Pence, B.C. 1997. N-acetyl transferase activity is 

decreased in rats fed high fat diets containing menhaden oil. FASEB J. 11: A578 

(#3345). 

66. Pence, B.C., Landers, M., Dunn, D.M., Shen, C.L., and Miller, M.F. 1997. 

Enhancement of colon and stomach carcinogenesis in rats fed a diet containing 

well-cooked meat with a high heterocyclic amine content. Gastroenterology 112: 

A638. 

67. Stewart, M., Grimson, M., Pence, B., and Bornhop, D., 1998. Polyazamacrocyclic 

Tb chelates: Investigations using a new biomarker for early detection of colon 

cancer. Proc. Am. Assoc. Cancer Res. 39: 337 (#2296). 

68. Shen, C.-L., Cowden, K.D., and Pence, B.C. 1998. Increasing levels of PhIP in the 

diet alter the activity of heterocyclic amine metabolizing enzymes in liver, stomach, 

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and colon of female Sprague-Dawley rats. Proc. Am. Assoc. Cancer Res.39:16 

(#106). 

69. Davis, R.L., Spallholz, J.E., and Pence, B.C. 1998. Copper inhibits seleniteinduced 

apoptosis and DNA fragmentation in human colonic carcinoma cells. 

FASEB J. 12: A564 

(#3273). 

70. Philips, B.U., Battles, J.B., Bowling, J.R., Bramson, R., Camp, M., Chang, H.M., 

Freytes, C.O., Kuratko, C., Laufman, L.E., Pence, B.C., Shores, J.H., Weinberg, 

A., and Burt, T.M. 1998. The Implementation of technology-based information into 

the Texas Medical School Consortium. J. Cancer Educ. 13S: 28 (#116). 

71. Shen, C.-L., Song, W., and Pence, B.C. 1999. Comparative abilities of selenium 

compounds in protection against UVB damage in normal human keratinocytes. 

Proc. Am. Assoc. Cancer Res. 40:360 (#2384). 

72. Shen, C.-L., Song, W., and Pence, B.C. 1999. Differential antioxidant and 

apoptotic effects of selenium compounds on human skin cells. FASEB J. 13: A247 

(218.2). 

73. Kuratko, C.N., Jones, B.G., Chauncey, K.B., Kirby, R.K., and Pence, B.C. 1999. 

Assessment of nutrition knowledge and attitudes of medical students graduating 

from a four-year traditional curriculum. FASEB J. 13: A550 (440.17). 

74. Chauncey, K., Kirby, R.K., Jones, B.G., Kuratko, C.N., and Pence, B.C. 1999. 

Nutrition knowledge scores: Graduating family practice residents vs. graduating 

medical students. Annual meeting, Society for Teachers of Family Medicine. 

75. Shen, C.-L., Song, W., and Pence, B.C. 2000. Effects of selenium compounds 

plus other antioxidants on cytotoxicity and DNA oxidative damage in normal 

human keratinocytes. FASEB J. 14: A537 #372.7. 


plus esterified glutathione on cytotoxicity, cellular glutathione level, and DNA 

oxidative damage in normal human keratinocytes. Proc. Am. Assoc. Cancer Res. 

41: 340 (#2160). 

77. Chauncey, K., Kuratko, C., Jones, B.G., Homan, R.V., and Pence, B.C. 2000. 

Charting a course for integrating nutrition training into medical education. Annual 

Meeting, AAMC, October 28-November 3, 2000, Chicago, IL. 

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plus ultraviolet B on glutathione peroxidase and DNA oxidative damage in skin of 

Skh:HR-1 hairless mice. Proc. Am. Assoc. Cancer Res. 42: 464 (#2496). 

79. Shen, C.-L., Song, W., and Pence, B.C. 2001. Differential apoptotic effects of 

selenium compounds on human colonic carcinoma cells. FASEB J. 15: A967 

(#744.6). 

80. Liu, Z., Shen, C.-L., Pence, B.C., and Kuratko, C.N. 2001 Production of 

inflammatory mediators during early colon carcinogenesis is increased by N-6 

fatty acids. American J. Clin. Path. 116:611. 

81. Shen, C.-L., Song, W., and Pence, B.C. 2002. Effects of dietary selenium 

compounds and glutathione modifiers on epidermal reduced glutathione in the 

ultraviolet light-exposed Skh: HR-1 mouse model. Proc. Am. Assoc. Cancer Res. 

43: 1143-44 (#5667). 

82. Pence, B.C., Shen, C.-L., and Song, W. 2002. Effects of dietary selenium 

compounds plus ultraviolet light on epidermal glutathione in the Skh: HR-1 

hairless mouse model. Proc. Am. Assoc. Cancer Res. 43: 1144 (#5668). 

83. Pence, B.C., Shen, C.-L., and Song, W. 2002. Effects of dietary selenium 

compounds and glutathione modifiers on epidermal glutathione peroxidase in the 

ultraviolet light-exposed Skh: HR-1 mouse model. FASEB J. 16: (A 605). 

84. Shen, C.-L., Oetama, B., Henry, J., and Pence, B. 2002. Differential effects of 

selenium compounds on nitric oxide production in an induced oxidative stress 

human osteoarthritic chondrocyte model. FASEB J. 16: (LB 286). 

85. Shen, C.-L., Graham, S., Morgan, D.L., Oetama, B., Brewton, L., and Pence, B. 

2002. Differential effects of selenium compounds on glutathione peroxidase and 

reduced glutathione in oxidative stress-induced human osteoarthritic synoviocyte 

model. FASEB J. 16: (LB 287). 

86. Pence, B. and Chaffin, W.L. 2002. First experience with a required RCR Course: 

Summary of responses to a student survey. AAMC GREAT meeting, Denver, CO. 

87. K.-J. Hong, D. M. Dunn, D.-F. Lo, C.-L. Shen, and B. C. Pence. 2003. Effects of 

Ganoderma lucidum on apoptotic and anti-inflammatory function in HT-29 human 

colonic carcinoma cells. Proc. Am. Assoc. Cancer Res.44: 425 (#1872). 

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88. K.-J. Hong, C.-L. Shen, and B. C. Pence. 2003. Apoptotic effects and antiinflammatory 

function of different selenium compounds in HT-29 colonic carcinoma 

cells. Proc. Am. Assoc. Cancer Res. 44: 893.(#3903). 

89. K-J. Hong, C.N. Hostrup, C-L. Shen and B.C. Pence. 2003. Inhibitory effects of 

Ling Zhi (Ganoderma lucidum) extract on inflammation and cytokine expression in 

human colonic carcinoma cells. FASEB J. 17:178 (#457.8). 

90. C.N. Hostrup, K-J. Hong, D.M. Dunn, C-L. Shen and B.C. Pence. 2003. Antioxidant 

and anti-inflammatory effects of herbal treatment Ling Zhi (Ganoderma 

lucidum), on human colonic carcinoma (HT-29) cells. FASEB J.17:178 (#457.9). 

91. K-J. Hong, C-L. Shen and B.C. Pence. 2003. Differential effects of selenium 

compounds on inflammation and cytokine expression in human colonic carcinoma 

cells. FASEB J.17:263 (#692.8). 

92. C.L. Shen, J. Huang, B. Oetama, M. Zumwalt and B.C. Pence. 2004. Effects of 

selenium compounds on the production of inflammatory mediators in human 

osteoarthritic chondrocytes. FASEB J. 18: A917 (#604.18). 

93. C.-L. Shen, D.D. Lo and B.C. Pence. 2004. Dietary n-3 polyunsaturated fatty acids 

modulate the production of inflammatory mediators in tissues of middle-age rats. 

FASEB J. 18: A7 (#36.5). 

94. K.-J. Hong, E. Cobos, and B.C. Pence. 2004. Anti-inflammatory and inhibitory 

effects of AHCC in A549 human lung cancer cells and HT-29 human colon cancer 

cells. http://www.faseb.org/eb2004/cite. 

95. B.C. Pence, D. Bustillos and A. Weinberg. 2007. Eliminating health disparities in 

cancer clinical trials: The EDICT Project. AACR “Science of Cancer Health 

Disparities Meeting”, Atlanta, GA. 

PUBLICATIONS: 

1. Felkner, I.C., K.M. Hoffman and B.C. Wells. 1979. DNA-damaging and mutagenic 

effects of 1,2-dimethylhydrazine on Bacillus subtilis repair-deficient mutants. 

Mutation Res. 68: 31-40. 

2. Shiau, S.Y., R.A. Huff, B.C. Wells and I.C. Felkner. 1980. Mutagenicity and DNAdamaging 

activity for several pesticides tested with Bacillus subtilis mutants. 

Mutation Res. 71: 169-179. 

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3. Buddingh, F., M.J. Bailey, B.C. Wells and J. Haesemeyer. 1981. Physiological 

significance of benzo(a)pyrene adsorbed to carbon blacks: elution studies, AHH 

determinations. J. Amer. Ind. Hygiene Assn. 42: 503-509. 

4. Wells, B.C., M.J. Wargovich and I.C. Felkner. 1981. Parameters for detection of 

mutagenesis of 1,2-dimethylhydrazine using an in vitro Bacillus subtilis system. 

Cancer Lett. 12: 287-294. 

5. Pence, D.B., L.A. Windberg, B.C. Pence and R. Sprowls. 1983. The epizootiology 

and pathology of sarcoptic mange in coyotes, Canis latrans from south Texas. J. 

Parasitol. 69: 1100-1115. 

6. Pence, B.C. and F. Buddingh. 1985. Effect of dietary selenium deficiency on 

incidence and size of 1,2-dimethylhydrazine-induced colon tumors in rats. J. Nutr. 

115: 1196-1202. 

7. Pence, B.C. and F. Buddingh. 1985. The effect of carbon black ingestion on 1,2dimethylhydrazine-induced 

colon carcinogenesis in rats and mice. Toxicol. Lett. 

25: 273-277. 

8. Pence, B.C. 1985. Fecal mutagens and Bacteroides fragilis levels in the feces of 

dimethylhydrazine-treated rats: influence of diet. Mutation Res. 158: 53-60. 

9. Pence, B.C., F. Buddingh and S.P. Yang. 1986. Multiple dietary factors in the 

enhancement of dimethylhydrazine carcinogenesis: main effect of indole-3carbinol. 

J. Natl. Cancer Inst. 77: 269-276. 

10. Pence, B.C. and F. Buddingh. 1987. Dietary effects on serum uric acid and lipid 

peroxides in 1,2-dimethylhydrazine-induced colon cancer in rats. Nutrition Res. 7: 

1093-1097. 

11. Reiners, J.J.Jr., B.C. Pence, M.C.S. Barcus and A.R. Cantu. 1987. 12-O- 

Tetradecanoylphorbol-13-acetate-dependent induction of xanthine dehydrogenase 

and conversion to xanthine oxidase in murine epidermis. Cancer Res. 47: 1775- 

1779. 

12. Pence, B.C. and F. Buddingh. 1987. Co-carcinogenic effect of carbon black 

ingestion with dietary fat on the development of colon tumors in rats. Toxicol. Lett. 

37: 177-182. 

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13. Pence, B.C. and J.J. Reiners, Jr. 1987. Murine epidermal xanthine oxidase 

activity: correlation with degree of hyperplasia induced by tumor promoters. 

Cancer Res. 47: 6388-6392. 

14. Pence, B.C. and F. Buddingh. 1988. Inhibition of dietary fat promoted colon 

carcinogenesis in rats by supplemental calcium or vitamin D 3 . Carcinogenesis 9: 

187-190. 

15. R.S. Riley and B.C. Pence. 1988. Letter to Q & A Editor: Answer to question: 

"Could you provide information on perspectives and supplier of in situ 

hybridization techniques in diagnostic pathology?". CAP Today, 2: 26. 

16. B.C. Pence. 1988. Book Review: Comparative Genetic Toxicology. J. Wildl. Dis. 

24: 725. 

17. B.C. Pence. 1989. Letter to the Editor, Re: Response to critique of Robertson and 

Koval. Toxicology Lett. 48: 319-320. 

18. Pence, B.C. and M.F. Naylor. 1990. Effects of single-dose ultraviolet radiation on 

skin superoxide dismutase, catalase, and xanthine oxidase in hairless mice. J. 

Invest. Dermatol. 95: 213-216. 

19. Pence, B.C., D.S. Demick, B.C. Richard and F. Buddingh. 1991. Effective nontoxic 

use of Dursban TM granules for the control of Myobia spp. in laboratory mice. 

Lab. Animal Sci. 41: 139-142. 

20. Pence, B.C. 1991. Dietary selenium and antioxidant status: toxic effects of 1,2dimethylhydrazine. 

J. Nutr. 121: 138-144. 

21. Kuratko, C.N. and B.C. Pence. 1991. Changes in colonic antioxidant status in rats 

during long-term feeding of different high fat diets. J. Nutr. 121: 1562-1569. 

22. Pence, B.C., S.-Y. Tsai and B.C. Richard. 1991. Effects of dietary fat on the 

hepatic microsomal metabolism of 1,2-dimethylhydrazine. Cancer Lett. 59: 225- 

229. 

23. Pence, B.C., B.C. Richard, R.S. Lawlis and C.N. Kuratko. 1991. Effects of dietary 

calcium and vitamin D 3 on murine skin tumor promotion. Nutr. Cancer 16: 171- 

181. 

24. B.C. Pence. 1991. Book Review: Antioxidant Nutrients and Immune Functions. J. 

Nutr. Immunol. 1: 109-110. 

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25. Kuratko, C.N. and B.C. Pence. 1992. Effects of dietary fat source on rat colonic 

antioxidant status during challenge with 1,2-dimethylhydrazine. J. Nutr. 122: 278- 

282. 

26. Cameron, G.S. and B.C. Pence. 1992. Effects of multiple applications of tumor 

promoters and ultraviolet radiation on murine epidermal antioxidant status and 

hyperplasia. J. Invest. Dermatol. 99: 189-192. 

27. Tsai, S.-Y. and B.C. Pence. 1992. Effects of dietary fat on hepatic microsomal and 

cytosolic activation of 2-aminofluorene. Cancer Lett. 67: 87-92. 

28. Pence, B.C. and D.M. Dunn. 1993. Vitamin D, cancer and immunity. J. Nutr. 

Immunol. 2: 109-125. 

29. Pence, B.C. 1993. Role of calcium in colon cancer prevention: experimental and 

clinical studies. Mutation Res. 290: 87-95. 

30. Kuratko, C.N., S.-Y. Tsai, and B.C. Pence. 1994. Effects of dietary fat and 1,2dimethylhydrazine 

on liver microsomal lipid peroxidation. J. Nutr. Biochem. 5: 78- 

83. 

31. Pence, B.C., E. Delver and D.M. Dunn. 1994. Effects of dietary selenium on UVBinduced 

skin carcinogenesis and epidermal antioxidant status. J. Invest. 

Dermatol. 102: 759-761. 

32. Pence, B.C.. 1995. Dietary selenium, skin cancer and antioxidant enzymes. Guest 

Editorial, The Nutrition Report, vol. 13. 

33. Pence, B.C., D.M. Dunn, C. Zhao, M. Landers, and M.J. Wargovich. 1995. 

Chemopreventive effects of calcium and aspirin supplementation in cholic acidpromoted 

colon carcinogenesis: correlation with intermediate endpoints. 

Carcinogenesis 16: 757-765. 

34. Pence, B.C., M.J. Butler, D.M. Dunn, M.F. Miller, C. Zhao and M. Landers. 1995. 

Non-promoting effects of lean beef in the rat colon carcinogenesis model. 

Carcinogenesis 16:1157-1160. 

35. Kuratko, C.N. and Pence, B.C. 1995. Dietary and tumor effects on colonic 

phospholipase A2. 1995. Cancer Lett. 95: 181-187. 

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36. Pence, B.C., D.M. Dunn, C. Zhao, M. Landers and S. Hunter. 1996. Elemental 

versus dairy calcium: effects on colon carcinogenesis and calcium 

compartmentalization. Nutr. Cancer 25: 35-45. 

37. Stewart, M.S., Cameron, G.S. and Pence, B.C. 1996. Antioxidant nutrients protect 

against UVB-induced oxidative damage to DNA of mouse keratinocytes in culture. 

J. Invest. Dermatol. 106: 1086-1089. 

38. Aukema, H.M., Davidson, L.A., Pence, B.C., Jiang, Y.-H., Lupton, J.R., and 

Chapkin, R.S. 1997. Butyrate alters activity of specific cAMP-receptor proteins in a 

transgenic mouse colonic cell line. J. Nutr.127: 18-24. 

39. Lai, C., Dunn, D.M., Miller, M.F., and Pence, B.C. 1997. Non-promoting effects of 

iron from beef in the rat colon carcinogenesis model. Cancer Lett. 112: 87-91. 

40. Stewart, M.S., Davis, R.L., Walsh, L.P. and B.C. Pence. 1997. Induction of 

differentiation and apoptosis by sodium selenite in human colonic carcinoma cells 

(HT29). Cancer Lett. 117: 35-40. 

41. Pence, B.C., Landers, M., Dunn, D.M., Shen, C.-L., and Miller, M.F. 1998. Feeding 

of a well-cooked beef diet containing a high heterocyclic amine content enhances 

colon and stomach carcinogenesis in rats. Nutr. Cancer 30: 220-226. 

42. Shen, C.-L., Purewal, San Francisco, S., and Pence, B.C. 1998. Absence of PhIP 

adducts, p53 and Apc mutations in rats fed a cooked beef diet containing a high 

level of heterocyclic amines. Nutr. Cancer 30: 227-231. 

43. Pence, B.C., Shen, C.-L., Dunn, D.M., Landers, M., Purewal, M., and San 

Francisco, S. 1998. Enhancement of colon and stomach carcinogenesis in 1, 2dimethylhydrazine-treated 

rats fed a diet high in heterocyclic amines. Zeit. 

Lebensmittel-untersuchung und-Forschung A. 207: 455-458. 

44. Davis, R.L., Spallholz, J.E. and Pence, B.C. 1998. Copper inhibition of seleniteinduced 

apoptosis in HT29 cells. Nutr. Cancer 32: 181-189. 

45. Stewart, M.S., Neldner, K.H., Spallholz, J.E. and Pence, B.C. 1999. Selenite, 

selenocystamine, and selenomethionine have disparate abilities to impose 

oxidative stress and induce apoptosis in mouse keratinocytes. Free Rad. Biol. 

Med.26: 42-48. 

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46. Bornhop, D.J., Hubbard, D.S., Houlne, M.P., Adair, C., Kiefer, G.E., Pence, B.C., 

and Morgan, D.L. 1999. Fluorescent tissue site-selective lanthanide chelate, Tb- 

PCTMB for enhanced imaging of cancer. Anal. Chem. 71:14: 2607-2615. 

47. Shen, C.-L., Song, W., and Pence, B.C. 2001. Interactions of selenium 

compounds with other antioxidants in DNA damage and apoptosis in human 

normal keratinocytes. Cancer Epidemiol. Biomarkers Prev., 10: 385-390. 

48. K.-J. Hong, D. M. Dunn, C.-L. Shen, and B. C. Pence. 2004. Effects of Ganoderma 

lucidum on apoptotic function in HT-29 human colonic carcinoma cells. 

Phytotherapy Res. 18:768-770. 

49. M.C. Esperat, D. Feng, Y. Zhang, Y. Masten, S. Allcorn, L. Velten, L. Billings, B. 

Pence, and M. Boylan. 2008. Transformation for Health: A framework for 

conceptualizing health behaviors in vulnerable populations. Nursing Clinics of North 

America 43: 381-395. 

50. Wells, R.S., Ruzabakiev, R., Kabulov, M., Yuldasheva, N. Khegai, T., Shen, C.-L. 

and Pence, B.C. High levels of oxidative damage in an Aral Sea population. In 

preparation. 

51. Pence, B.C. and C.-L. Shen. Why selenium is not an effective skin cancer 

chemoprevention agent. J. Invest. Dermatol. In revision. 

52. Pence, B.C. and C.-L. Shen. Effects of different selenium compounds on UVBinduced 

skin tumorigenesis. In preparation. 

BOOK CHAPTERS: 

1. Pence, B.C. and F. Buddingh. 1987. Effect of selenium deficiency on 1,2dimethylhydrazine-induced 

colon cancer in rats. In: G.F. Combs, Jr., J.E. 

Spallholz, O.A. Levander and J.E. Oldfield (eds.), Third International Symposium 

on Selenium in Biology and Medicine. AVI Publishing Co., Inc., Westport, CT. pp. 

1053-1059. 

2. Fischer, S.M., J.J. Reiners, Jr., B.C. Pence, C.M. Aldaz, C.J. Conti, R.J. Morris, J.F. 

O'Connell, J.B. Rotstein and T.J. Slaga. 1988. Mechanisms of carcinogenesis 

using mouse skin: the multistage assay revisited. In: R. Langenbach, J.C. Barrett 

and E. Elmore (eds.), Tumor Promoters: Biological Approaches for Mechanistic 

Studies and Assay Systems. Raven Press, New York, pp. 11-30. 

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3. Pence, B.C. 1991. Calcium and vitamin D effects on tumor promotion in rat colon 

and mouse skin. In: M. Lipkin, H. Newmark, and G. Kelloff (eds.), Calcium, 

Vitamin D and Prevention of Colon Cancer, CRC Press, Boca Raton, FL, pp. 191- 

208. 

4. Pence, B.C. 1992. Micronutrients and colorectal cancer risk: implications for 

chemoprevention. In: F.P. Rossini, H.T. Lynch and S.J. Winawer (eds.), Fifth 

International Symposium on Colorectal Cancer: Biology and Management of High 

Risk Groups, Elsevier, Amsterdam, pp. 171-174. 

5. Pence, B.C., C. Zhao, M. Landers and M.J. Wargovich. 1994. Modulation of colonic 

protein kinase C by dietary bile acids, calcium carbonate, and aspirin. Proc. of the 

XVI International Cancer Congress, New Delhi, India, Monduzzi Editore, 

Bologna,pp. 577-581. 

6. Pence, B.C. 1996. Nutrition and women‟s cancers: breast, cervical, endometrial and 

ovarian. In: I. Wolinsky and Klimas-Tavantzis, (eds.), Nutrition Concerns of 

Women, CRC Press, Boca Raton, FL. pp. 193-211. 

7. Yang, C.S., Pence, B.C., Wargovich, M.J. and Landau, J.M. 1996. Diet, Nutrition, 

and Cancer: Research Opportunities, Approaches, and Pitfalls”, In Dietary 

Phytochemicals in Cancer Prevention and Treatment. (Edited under the auspices 

of the American Institute for Cancer Research, Vol. 401, pp. 231-238, Plenum 

Press, New York. 

8. Pence, B.C. and Yang, T.C. 1999. Antioxidants: radiation and stress, In, H. Lane 

and D.A. Schoeller, (eds.), Nutrition in Space Flight and Weightlessness Models, 

CRC Press, pp. 233-251. 

9. Pence, B.C. 2003. Nutrition and women‟s cancers: breast, cervical, endometrial 

and ovarian. In: I. Wolinsky and Klimas-Tavantzis, (eds.), Nutrition Concerns of 

Women, 2 nd Ed., CRC Press, Boca Raton, FL., pp. 341-363 . 

10. Pence, B.C. 2007. Metabolic Abnormalities. In: Quattromani, F., ed. Pediatric Q & 

A. New York, NY. Thieme Publishers; pp. 232-239 

BOOKS: 

1. Pence, B.C. and Dunn, D.M., 1998. Nutrition and Women‟s Cancers, CRC Press, 

Boca Raton, FL, 179 pp. 

30

TEACHING EXPERIENCE: 


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Attendee, Workshop "Options in Medical Education", University of New Mexico School 

of Medicine, Feb. 3-7, 1992 (problem-based learning) 

TTUHSC School of Medicine: Coordinator for Nutrition in the Medical Curriculum, 1990- 

2000 

Member, CATCHUM Project Steering Committee to develop cancer prevention and 

early detection modules and standardized patient scenarios for the undergraduate 

medical curriculum, 1992-present 

Lecturer, MPA 61745 Pathology/ Pathophysiology Course, on Cell Injury and 

Adaptation, Molecular Biology, Neoplasia, and Nutritional Diseases, for sophomore 

medical students (16-22 lecture hours), 1987-present 

Course Director: F & N 5350, Nutritional Pathophysiology, for graduate students and 

Registered Dietitian interns (3 semester hours), 1988-1993 

Course Director: BCH 6335/F & N 5311, Nutritional Biochemistry, for graduate students 

(3 semester hours), 1990 

Guest Lecturer: PHM 5335, Cellular and Molecular Toxicology, for graduate students, 

lectures on carcinogenesis and tumor promotion, 1989 

Lecturer, Medical Biochemistry, for freshman medical students (5 lecture hours), on 

nutritional aspects of biochemistry, 1990-1993 

Course Director, MPA 50101, Clinical Nutrition Elective for freshman medical students, 

1990-1994 

Guest Lecturer, AHMT Clinical Chemistry course for medical technology students on 

tumor markers and laboratory diagnosis of nutritional status, 1991 

Lecturer, Physical Therapy Pathology, PT 5203, lectures on neoplasia and diseases of 

the skin, 1993-present 

Guest Lecturer, Medical Aspects of Health Organization Management for MBA 

students, on cancer epidemiology and management of cancer issues, 1994-present 

Guest Lecturer, F & N 5350, Nutritional Pathophysiology, for graduate students and 

dietetic interns, on immunology and cancer, 1994 

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Lecturer, Introduction to Medicine, for sophomore medical students, on gastrointestinal 

function and nutrition topics, 1995 – 97 

Course Director, GSBS 5101, Responsible Conduct of Research, required of all 

graduate students and clinical research fellows, 2001-present 

Course Director, Clinical Research Fellowship, 2001 

Facilitator, 3 PBL cases in geriatrics curriculum, 2001-2002 

MSI Lectures on Cancer Genetics and Nutrition (4 lecture hours), 2005-2006 

STUDENTS SUPERVISED: 

Connye Kuratko, Ph.D. student, Division of Food and Nutrition, Texas Tech 

University, Chairperson, Graduate Advisory Committee, graduation date: August 

1991. 

Richard Stephen Lawlis, Medical Student II, 1989 Summer Research Fellowship, 

Faculty Mentor 

Shwu-Yar Tsai, Ph.D. student, Division of Food and Nutrition, Texas Tech 

University, Chairperson, Graduate Advisory Committee, graduation date: May 

1993. 

Marjory Stewart, Ph.D. student, Division of Food and Nutrition, Texas Tech 

University, Chairperson, Graduate Advisory Committee, graduation date: May 

1996. 

Erica Delver, M.S. student, Division of Food and Nutrition, Texas Tech 

University, Chairperson, Graduate Advisory Committee, graduation date: August 

1993. 

Vijay Patel, Medical Student II, 1992 Summer Research Fellowship, Faculty 

Mentor 

Bing Shi, Ph.D. student, Division of Food and Nutrition, Texas Tech University, 

Member, Graduate Advisory Committee, graduation date: May, 1994 

Micah Butler, M.S. student, Department of Animal Science and Food 

Technology, Texas Tech University, Member, Graduate Advisory Committee, 

graduation date: August 1995. 

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Jau-Jiin Chen, Ph.D. student, Division of Food and Nutrition, Texas Tech 

University, Member, Graduate Advisory Committee, graduation date: December 

1996. 

Lugen Chen, Ph.D. student, Division of Food and Nutrition, Texas Tech 

University, Member, Graduate Advisory Committee, graduation date: May 1997. 

Melanie Landers, M.S. student, Division of Food and Nutrition, Texas Tech 

University, Chairperson, Graduate Advisory Committee, left program 

Michael Dixon, Medical Student I, summer research fellow, Texas Tech Health 

Sciences Center, Faculty Mentor, 1995 

Chris Lai, M.S. student, Department of Animal Science and Food Technology, 

Texas Tech University, Member, Graduate Advisory Committee, graduation date: 

August 1996 

Randy Davis, Ph.D. student, Division of Food and Nutrition, Texas Tech 

University, Member, Graduate Advisory Committee, graduation date May 1998. 

Amit Kumar, undergraduate student, Department of Biological Sciences, Texas 

Tech University, Faculty Mentor, 1995-1997. 

Karen Cowden, undergraduate student, Howard Hughes Medical Institute Fellow, 

Texas Tech University, Faculty Mentor, 1997-1999. 

Cecily Hostrup, undergraduate student, Texas Tech University, 2001-2002. 

Haitao Luo, PhD student, TIEHH and Dept. of Environmental Toxicology, 

Member, Graduate Advisory Committee, graduation date August 2005. 

Madhavi Billam, PhD student, TIEHH and Dept. of Environmental Toxicology, 

Member, Graduate Advisory Committee, graduation date May 2006. 

Zemin Wang, PhD student, TIEHH and Dept. of Environmental Toxicology, 

Member, Graduate Advisory Committee, graduation date August, 2007. 

Li Xu, PhD student, TIEHH and Dept. of Environmental Toxicology, Member, 

Graduate Advisory Committee, graduation date December 2009. 

POSTDOCTORAL FELLOWS TRAINED: 

33

Marjory Stewart, 1996-97 

Leslie Shen, 1996-1998 

Kevin Hong, 2002-2004 


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34

Barbara C. Pence - Texas Tech University Health Sciences Center

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