Oscillations, Waves, and Interactions - GWDG

DPI60plus – a future with biophysics 443
Figure 5. Height distribution of MTs. Undecorated MTs show an average diameter of
25.9 nm at a loading force of < 0.1 nN. When MTs are preincubated with tau the height
increased by 2.2 nm. Kinesin added 4.5 nm to the MT height. Note that the 2.2 nm are caused
by tau binding all around MTs while kinesin is bound to MTs just on one side because
in this case MTs were attached to the surface before addition of kinesin. The differences
between the three distributions were tested for statistical significance by a Student’s t-test.
The probability that any pair of the measured distributions belong to the same parent
distribution was estimated to be smaller than 0.1 % by applying the Student’s t-test for
samples with an unequal variance. (From Ref. [1]).
Figure 6. Calculated dependence of F/E on CCMV-capsid deformation for R = 14.3 nm,
h = 3.8 nm, and s = 0.4. The images above the curve show a one-quarter segment of the
capsid at indentations d = 0, 5.6, and 14 nm, and the von Mises stress is indicated by the
colour. The image below the curve shows the buckling of the capsid away from the tip that
is mirrored by a decrease in the slope. (From Ref. [5]).