Essential Cell Biology 5th edition

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I:12 Indexheart muscleacetylcholine effects 543contraction 605, 707heart attacks 55, 526, 716mitochondria in 459–460heart pacemaker cells 537, 538F, 548,556heat loss 84helicesactin double helix 134, 593Fcollagen triple helix 135, 136F, 696in common folding patterns127–128DNA/RNA hybrid 231, 319DNA double-helix formation 58,175–176superhelices 696see also a helices (at “alpha”)heme group 133F, 148F, 149, 305F, 474,475Fhemidesmosomes 578F, 704, 707, 708Fhemoglobinearly investigation ofmacromolecules 60–61fetal and adult 305nonprotein constituent 149sickle-cell anemia 222, 680subunits 133, 304–305see also globinshemophilia 239F, 307, 317, 334, 672,680hemopoietic stem cells 714–715hepatocyte growth factor 644hereditary diseases see geneticdisorders“hereditary factors” 666heredity and DNA structure 176–178,327–328see also inheritanceheroin 544Hershey, Alfred 195heterochromatin 184F, 189–191, 277,291, 321–322Fheterozygous individuals 666–670,672–673, 675F, 677, 680–682, 684Fhexokinase 137, 142, 436Fhexosaminidase 682hibernation 465, 477“high-energy” bonds and theirhydrolysis 67F, 95F, 102–103, 109F,111, 112Fsee also ATP; GTP“high-energy” electronsATP production from 461–463from chlorophyll 463, 479, 482in NADH 107“high-energy” intermediate 476–477Hill, Archibald (A. V.) 102HindIII enzyme 335–336Fhistones 184–191histone H1 187histone H3 185–186, 189F, 190–191histone H4 185–186, 189Fhistone H2A 185, 186F, 189Fhistone H2B 185, 186F, 189Fand the nucleosome 184–186histone acetyltransferases/deacetylases277histone-modifying enzymes 188–190,277Fhistone octamers 185–186, 188histone tails, modification 186, 189–191,277, 287historical landmarkscell structure determination 24Tunderstanding of proteins 160THIV (human immunodeficiency virus)318T, 319F, 320, 344F, 526, 680,682HMG-CoA reductase 147Hodgkin, Alan 413homeodomains 272–273Fhomologous chromosomes 179, 184F,304F, 345Fmaternal and paternal 179, 652in meiosis 652, 655–659, 661F, 671F,679homologous genesin comparative genomics 309and proteins 35homologous recombinationin DNA repair 220–222gene duplication and rearrangement303, 308in meiosis 653, 658production of transgenic mice 356Fhomophilic binding 705, 711Hooke, Robert 7, 24T, 693horizontal gene transferantibiotic resistance through 308,338genetic change through 298, 299F,308hormones, in extracellular signaling534, 535F, 536Tsee also epinephrine; insulin; steroidshousekeeping proteins 270HPr bacterial protein 124, 125–126F, 129human genetics 678–687human genomeAfrican origins and 320F, 326–327F,679–680animal counterparts 33compared with other species 309,310–311conserved proportion 323disease predisposition 679exon shuffling contribution 307and human individuality 327–328mobile genetic elements in 316–317Neanderthals and 326, 327Fnoncoding RNAs 289, 291size and number of genes 179, 320F,322T, 324–325tRNA genes 248see also genome sequenceshuman genome sequencing project 346,348–349human papillomavirus 720human studies 32–34Hunchback gene 281FHunt, Tim 31, 616Huxley, Andrew 413hyaluronan 700, 701Fhybrid cells, mouse–human 381hydra 652hydride ions 107–108, 431T, 432hydrocarbon tails, lipids 367, 371–372,377Fhydrocarbons, saturated andunsaturated 66Fhydrogels 158hydrogen-bondingin a helices and b sheets 128–129,377–378as noncovalent 47in nucleic acids 58, 70F, 175–176,177Fin proteins 70F, 121, 122F, 126, 127Fat replication origins 201in RNA structures 230F, 248, 260strengths of A-T and C-G 177F, 201in water 47, 68F, 70Fhydrogen gas as a nutrient 491hydrogen molecules 44Fhydrogen peroxide see peroxisomeshydrogen sulfide (H 2S) 489hydrogenations as reductions 88hydrolysis 53“high-energy” bonds 95Fproteolysis as 256hydronium ions 49, 69hydrophilicity 47, 68F, 369, 701hydrophobic interactionsas noncovalent 48, 62, 71Fin protein conformations 121, 122Fsee also amphipathic moleculeshydrophobicity 47–48, 68F, 369signal sequences 503hydrothermal vents 488, 490hydroxyl ions 49F, 50–51, 69Fhypervariable loops 139hypothalamus 421, 422FIIllumina sequencing 347, 351Fimatinib 148, 729immune systemcomplement system 685and stem cell potential 716use against cancers 728immunoaffinity chromatography 141FImmunofluorescence microscopy 575Fimmunoprecipitation 141Fco-immunoprecipitation 563, 730import signals see signal sequencesin situ hybridization 352in vitro fertilization 161in vivo and in vitro studies 32inactivation, voltage-gated ion channels414indels 679independent assortment, law of669–671indigo 145induced pluripotent stem cells (iPScells) 285–286, 716–718infection diagnosis and PCR 343influenza virus 318T, 319F, 526inheritancelaws of 664–674uniparental 664F, 665see also geneticsinherited diseases see genetic disordersinitiator tRNA 253inositol 1,4,5-trisphosphate (IP 3) 549,551–552, 553Finositol phospholipid pathway 552–553inositol phospholipids 374, 552, 553F,559, 561Inoué, Shinya 588insertion mutations 307insulinisolation 563secretion stimulated by glucose 522insulin-like growth factor (IGF) family560–561
IndexI:13integrases 319integrinsin cell adhesion 698–700, 702,706–707in cell locomotion 597, 699in cytokinesis 637interaction domains 558–559interference-contrast optics 9F, 12Fintermediate filaments 22F, 23, 135,574–579, 630, 693desmosome connection 705, 706F,708Fsee also keratin filamentsinterphase, cell cycle 181, 611, 628Finterphase chromosomes 181–184,185F, 187, 189–192, 277interspersed (“junk”) DNA 180, 181Fintestinal cell renewal see cryptsintracellular compartments 19–21see also organellesintracellular condensates 157, 158F, 242intracellular signaling molecules 79Fintracellular signaling pathwayselucidation 563–564GPCR-triggered 555–557, 562Fintegration by 568, 569Fresponse to extracellular signals539–540RTK-activated 562Fintracellular signaling proteinsas molecular switches 541–542RTK activation 558–559intrinsically disordered sequences 131introns (intervening sequences)239–241, 244F, 298, 302, 312–313,320–322F, 323–325iodoacetate 102ion-channel-coupled receptors 543–545acetylcholine activated 543also known as transmitter-gated ionchannels 417–419, 544ion channelsdirect G protein regulation 548examples 419Tnerve signaling and 410–422patch-clamp recording 160T,407–408, 411Fselectivity and gating 404–405,408–409see also gatingion concentrations inside and outsidecells 391, 399see also concentration gradientsion-exchange chromatography 166Fionic chemical bonds 42–43, 46–47, 79Fions, impermeability of lipid bilayers391IP 3(inositol 1,4,5-trisphosphate) 549,551–552, 553Fironatmospheric oxygen and 490Fheme group 133F, 148F, 149, 305F,474, 475Freceptor-mediated endocytosis 526iron–sulfur centers 473, 483F, 489Fisocitrate dehydrogenase 443Fisoelectric focusing 167Fisomerases 142T, 431, 436F, 448isomersmonosaccharides 52, 72Foptical isomers 53, 56, 76F, 142isotopes 40–41see also radiolabelingJJews, Ashkenazi 682joules, conversion with calories 45, 94Fjumping genes see mobile geneticelements“junk DNA” 180KK + leak channels 375T, 405, 406F, 413,415, 419TKartagener’s syndrome 592karyotypes 179F, 180, 721, 722Fkeratin/a-keratin 118F, 126, 128, 135,575F, 577, 578F, 579keratin filaments 135, 577, 578F, 705,706F, 707, 714Fsee also intermediate filamentsa-ketoglutarate (dehydrogenase)441–444Khorana, Gobind 246–247killer lymphocytes 642, 728kinesins 118F, 586–587, 589, 634kinetics, enzyme 144see also reaction rateskinetochores 628F–629F, 631–634, 635F,660, 661FKit gene 34FK M(Michaelis constant) 143, 144“knock-in mice” 355F“knockout mice” 356–357, 731Krebs, Hans 444–445Krebs cycle see citric acid cycleKrüppel gene 281FLL1 element (LINE-1) 311F, 316–317,322FLac operon 275–276, 279lactase gene 302, 303Flactate dehydrogenase 131F, 447lactic acid cycle 102Lactobacillus 2lactose 73F, 275, 302, 303Flagging strand, DNA replication205–210, 211F, 212–213, 214Flamellipodia 596–599laminin 702, 703F, 707lamins 577–579, 635, 636F, 641“lariat” structures 240, 241Flasers 12F–13F, 159, 384, 633last common ancestorof plants and animals 567latent viruses 319latrunculin 594laws of inheritanceMendel’s first law 666–668Mendel’s second law 669–671laws of thermodynamicsfirst 84second 83–84, 90LDL (low-density lipoproteins) 525–526leading strand, DNA replication 207,209, 211F, 212–213lectins 383, 386Leder, Phil 247Leeuwenhoek, Antoni van 7, 24Tleptin gene/protein 311–312Fleucocyte adhesion deficiency 699leukemia 148, 714F, 715, 729life see living thingslifestyle factors and cancer 719, 721ligand-gated ion channels 408,417–418transmitter-gated ion channels417–419, 543F, 544ligands, defined 137see also substratelight-driven proton pumps 402,545light-gated ion channels 408, 417–418,421, 422Flight microscopesand the discovery of cells 6–7and the structures of cells 7–9see also fluorescence microscopylight reactions (photosynthesis) 479,484, 486, 487Flignin 694LINEs (long interspersed nuclearelements) 322FL1 element 311F, 316–317, 322Flinker DNA 185, 186Flinker histones (histone H1) 187linker proteins 506F, 579, 580F, 705,707lipid bilayers 367–374essential fluidity 370–373, 384–385fatty acid derivatives as 55formation in aqueous media367–370limited permeability 390–391and lipid aggregates 75Fprotein association with 366, 376as self-sealing 366, 370synthetic/artificial bilayers 371,385, 390Flipidsdolichol 75F, 516, 517FER as a source 373hydrophobic interactions 48types 74F–75Fsee also glycolipids; phospholipidsLipmann, Fritz 102–103liposomes 371, 390F, 477Listeria monocytogenes 289Fliving thingsautocatalysis requirement 5F,259–260cells as fundamental units 1characteristics 1, 4, 39chemical composition 39number of species 2origins of life 309–315spontaneous generation 7ultimate dependence on solarenergy 86local mediators 535–536, 545, 550T,555, 557logic operations 275logos (for DNA sequences) 273FLohmann, Karl 103Loligo pealei (squid) 411F, 412long noncoding RNAs 289, 291–292loss-of-function mutations 672–673,682, 685–686, 724Lou Gehrig’s disease 578LoxP recombination sites 357Flumen, organelles 374Lundsgaard, Einar 102–103lysine residuesacetylation 153, 189–191, 277methylation 189F, 190–191
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ESSENTIALCELL BIOLOGYFIFTH EDITION
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W. W. Norton & Company has been ind
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viPrefaceanswer and others invite s
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viiiPrefaceDenise Schanck deserves
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ABOUT THE AUTHORSBRUCE ALBERTS rece
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xiiList of Chapters and Special Fea
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PrefacexvCONTENTSPreface vAbout the
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ContentsxviiThe Equilibrium Constan
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ContentsxixCHAPTER 6DNA Replication
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ContentsxxiPOST-TRANSCRIPTIONAL CON
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ContentsxxiiiCHAPTER 11Membrane Str
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ContentsxxvCHAPTER 14Energy Generat
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ContentsxxviiCHAPTER 16Cell Signali
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ContentsxxixCHAPTER 18The Cell-Divi
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ContentsxxxiGENETICS AS AN EXPERIME
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CHAPTER ONE1Cells: The FundamentalU
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Unity and Diversity of Cells3mechan
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Unity and Diversity of Cells5nucleo
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Cells Under the Microscope7The Inve
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Cells Under the Microscope9cytoplas
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The Prokaryotic Cell110.2 mm(200 µ
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The Prokaryotic Cell13SUPER-RESOLUT
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The Prokaryotic Cell15(A)HSV10 µmF
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The Eukaryotic Cell17nucleusnuclear
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The Eukaryotic Cell19chloroplastsch
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The Eukaryotic Cell21lysosomenuclea
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The Eukaryotic Cell23duplicatedchro
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PANEL 1-2 CELL ARCHITECTURE 25ANIMA
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Model Organisms27(C)(D)(A) (B) (E)
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Model Organisms29Figure 1-34 Drosop
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Model Organisms31INTRODUCE FRAGMENT
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Model Organisms33(A) (B) (C)50 µm
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Model Organisms35TABLE 1-2 SOME MOD
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Questions37• Free-living, single-
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CHAPTER TWO2Chemical Components of
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Chemical Bonds41number of protons.
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Chemical Bonds43+atoms+SHARING OFEL
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Chemical Bonds45Four electrons can
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Chemical Bonds47Because of the favo
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Chemical Bonds49Some Polar Molecule
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Small Molecules in Cells51with othe
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Small Molecules in Cells53optical i
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Small Molecules in Cells55can be re
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Small Molecules in Cells57O _O _ ph
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Macromolecules in Cells59Figure 2-3
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Macromolecules in Cells61ultracentr
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Macromolecules in Cells63BBAAthe su
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Questions65KEY TERMSacid electrosta
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67C-O COMPOUNDSMany biological comp
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69WATER AS A SOLVENTMany substances
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71ELECTROSTATIC ATTRACTIONSElectros
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73α AND β LINKSThe hydroxyl group
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75LIPID AGGREGATESFatty acids have
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77ACIDIC SIDE CHAINSNONPOLAR SIDE C
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79NOMENCLATUREThe names can be conf
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CHAPTER THREE3Energy, Catalysis, an
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The Use of Energy by Cells83(A) (B)
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The Use of Energy by Cells85ABraise
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The Use of Energy by Cells87H 2 OPH
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Free Energy and Catalysis89thermody
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Free Energy and Catalysis91lake wit
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Free Energy and Catalysis93FOR THE
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Free Energy and Catalysis95REACTION
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Free Energy and Catalysis97to the c
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Free Energy and Catalysis99Figure 3
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Activated Carriers and Biosynthesis
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Essential Concepts113ESSENTIAL CONC
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Questions115a kilocalorie (kcal) is
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118 PANEL 4-1 A FEW EXAMPLES OF SOM
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120 CHAPTER 4 Protein Structure and
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140PANEL 4-2 MAKING AND USING ANTIB
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144HOW WE KNOWMEASURING ENZYME PERF
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164 PANEL 4-3 CELL BREAKAGE AND INI
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166PANEL 4-4 PROTEIN SEPARATION BY
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168PANEL 4-6 PROTEIN STRUCTURE DETE
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174 CHAPTER 5 DNA and ChromosomesTh
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176 CHAPTER 5 DNA and Chromosomes5
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178 CHAPTER 5 DNA and Chromosomes(A
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180 CHAPTER 5 DNA and ChromosomesFi
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182 CHAPTER 5 DNA and ChromosomesY
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184 CHAPTER 5 DNA and ChromosomesFi
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186 CHAPTER 5 DNA and Chromosomesli
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188 CHAPTER 5 DNA and ChromosomesTH
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190 CHAPTER 5 DNA and Chromosomeshe
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192 CHAPTER 5 DNA and Chromosomesge
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194CHAPTER 5DNA and Chromosomesform
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196 CHAPTER 5 DNA and ChromosomesQU
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198 CHAPTER 5 DNA and ChromosomesQU
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200 CHAPTER 6 DNA Replication and R
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202HOW WE KNOWTHE NATURE OF REPLICA
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204CHAPTER 6DNA Replication and Rep
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228 CHAPTER 7 From DNA to Protein:
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246HOW WE KNOWCRACKING THE GENETIC
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CHAPTER EIGHT8Control of Gene Expre
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An Overview of Gene Expression269(A
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How Transcription Is Regulated271de
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How Transcription Is Regulated273tr
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How Transcription Is Regulated275Li
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How Transcription Is Regulated277fo
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Generating Specialized Cell Types27
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Post-Transcriptional Controls287Alt
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Post-Transcriptional Controls289rib
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Post-Transcriptional Controls291At
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Questions293• MicroRNAs (miRNAs)
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Questions295specialized cells is ba
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298 CHAPTER 9 How Genes and Genomes
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324HOW WE KNOWCOUNTING GENESHow man
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5′ 3′5′3′330 CHAPTER 9 How
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CHAPTER TEN10Analyzing the Structur
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Isolating and Cloning DNA Molecules
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IIIIIIIIIIIIIDNA Cloning by PCR341D
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DNA Cloning by PCR343HEAT TOSEPARAT
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DNA Cloning by PCR345(A)ANALYSIS OF
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Sequencing DNA347single-stranded DN
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Sequencing DNA349repetitive DNAinte
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Exploring Gene Function351each loca
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Exploring Gene Function353(A)CONSTR
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Exploring Gene Function355E. coli,
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Exploring Gene Function357(A)(B)Fig
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Exploring Gene Function359fused to
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Exploring Gene Function361Figure 10
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Questions363• DNA sequencing tech
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CHAPTER ELEVEN11Membrane StructureA
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ECB5 e11.05/11.05The Lipid Bilayer3
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The Lipid Bilayer369hydrogen bondsC
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The Lipid Bilayer371sets a lower li
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The Lipid Bilayer373Figure 11-16 Ne
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Membrane Proteins375TRANSPORTERS AN
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Membrane Proteins377A Polypeptide C
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Membrane Proteins379Figure 11-26 SD
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Membrane Proteins381spectrin dimera
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Membrane Proteins383apical plasmame
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ECB5 e11.36/11.36Membrane Proteins3
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Questions387• Most cell membranes
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CHAPTER TWELVE12Transport Across Ce
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Principles of Transmembrane Transpo
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Principles of Transmembrane Transpo
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Transporters and Their Functions395
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Ion Channels and the Membrane Poten
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Ion Channels and Nerve Cell Signali
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Essential Concepts423• Ion channe
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Questions425QUESTION 12-18Amino aci
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428 CHAPTER 13 How Cells Obtain Ene
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436PANEL 13-1 DETAILS OF THE 10 STE
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442PANEL 13-2 THE COMPLETE CITRIC A
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444HOW WE KNOWUNRAVELING THE CITRIC
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CHAPTER FOURTEEN14Energy Generation
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Energy Generation in Mitochondria a
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Mitochondria and Oxidative Phosphor
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Molecular Mechanisms of Electron Tr
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Chloroplasts and Photosynthesis479c
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Chloroplasts and Photosynthesis481F
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Chloroplasts and Photosynthesis483T
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Chloroplasts and Photosynthesis485r
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Chloroplasts and Photosynthesis487s
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The Evolution of Energy-Generating
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Essential Concepts491(A)1 µm(B)Fig
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Questions493C. The electrochemical
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CHAPTER FIFTEEN15Intracellular Comp
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Membrane-Enclosed Organelles497mito
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Membrane-Enclosed Organelles499DNAm
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Protein Sorting501proteins that are
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Protein Sorting503they have the sam
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Protein Sorting505prospective nucle
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Protein Sorting507the first six mon
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Protein Sorting509mRNAgrowingpolype
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Vesicular Transport511hydrophobicst
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Vesicular Transport513(A)(C)25 nm(B
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Secretory Pathways515receptorcargo
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Secretory Pathways517KEY:= glucose=
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Secretory Pathways519cisGolginetwor
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Secretory Pathways521ERGolgiapparat
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Endocytic Pathways523protein in the
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Endocytic Pathways525shed their coa
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Endocytic Pathways527Figure 15−35
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Essential Concepts529• Nuclear pr
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Questions531their destination. Thus
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534 CHAPTER 16 Cell Signalingconsid
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536 CHAPTER 16 Cell Signalingcontac
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538 CHAPTER 16 Cell Signaling(A) he
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540 CHAPTER 16 Cell SignalingFigure
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544 CHAPTER 16 Cell SignalingTABLE
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548 CHAPTER 16 Cell Signalinga diff
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554 CHAPTER 16 Cell Signalingby mem
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556 CHAPTER 16 Cell Signalingouters
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ECB5 e16.32/16.29558 CHAPTER 16 Cel
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562 CHAPTER 16 Cell Signalinggrowth
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564CHAPTER 16Cell Signalinginvolve
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570 CHAPTER 16 Cell Signalingcyclas
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572 CHAPTER 16 Cell SignalingQUESTI
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574 CHAPTER 17 CytoskeletonFigure 1
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576 CHAPTER 17 Cytoskeleton(A)NH 2C
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578 CHAPTER 17 Cytoskeletonbasal ce
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582 CHAPTER 17 Cytoskeletonnucleati
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586 CHAPTER 17 CytoskeletonQUESTION
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588HOW WE KNOWPURSUING MICROTUBULE-
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594 CHAPTER 17 Cytoskeletonactin wi
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596 CHAPTER 17 Cytoskeletonof actin
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598 CHAPTER 17 Cytoskeletonplus end
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myofibrils602 CHAPTER 17 Cytoskelet
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606 CHAPTER 17 CytoskeletonThe cont
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608 CHAPTER 17 CytoskeletonQUESTION
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610 CHAPTER 18 The Cell-Division Cy
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616CHAPTER 18The Cell-Division Cycl
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628PANEL 18-1 THE PRINCIPAL STAGES
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CHAPTER NINETEEN19Sexual Reproducti
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The Benefits of Sex653Figure 19−2
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Meiosis and Fertilization655In this
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Meiosis and Fertilization657(A)MITO
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Meiosis and Fertilization659duplica
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Meiosis and Fertilization661(A)(B)m
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Meiosis and Fertilization663gamete
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Mendel and the Laws of Inheritance6
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PANEL 19-1 SOME ESSENTIALS OF CLASS
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Genetics as an Experimental Tool677
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Exploring Human Genetics679With the
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Exploring Human Genetics681remainde
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Exploring Human Genetics683prevalen
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Exploring Human Genetics685Such lin
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Essential Concepts687and function a
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Questions689C. Genotype and phenoty
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CHAPTER TWENTY20Cell Communities: T
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Extracellular Matrix and Connective
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Epithelial Sheets and Cell Junction
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Stem Cells and Tissue Renewal709cyt
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Stem Cells and Tissue Renewal711epi
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Stem Cells and Tissue Renewal713LUM
Page 749 and 750:
Stem Cells and Tissue Renewal715SEL
Page 751 and 752:
Stem Cells and Tissue Renewal717reg
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Cancer719normal epithelial cellprim
Page 755 and 756:
Cancer721Figure 20−43 Cancer inci
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Cancer7232. Cancer cells can surviv
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Cancer725(B)(A)loss-of-function mut
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Cancer727(A)Figure 20-50 Colorectal
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Essential Concepts729Figure 20-53 A
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731It turns out that APC regulates
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Questions733KEY TERMSadherens junct
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AnswersChapter 1ANSWER 1-1 Trying t
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Answers A:3proteins, nucleic acids,
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Answers A:5B. The volume of the pag
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Answers A:7X YYYY Zenzyme lowers th
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Answers A:9ANSWER 3-16A. From Table
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Answers A:11on its surface; however
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Answers A:13rate (µmole/min)210 5
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Answers A:15transcriptionally inact
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Answers A:17HNNadenineNNHNH 2NH 2NO
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Answers A:19(A) NORMALsplicing173 b
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Answers A:21Figure A8-2minor groove
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5′ 3′3′Answers A:23proliferat
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Answers A:25that its function is ve
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Answers A:27additional fragments ge
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Answers A:29slightly water-soluble,
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Answers A:311 2 3 4OUTSIDEFigure A1
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Answers A:33ANSWER 12-21 The membra
Page 803 and 804: Answers A:35STEP1STEP2STEP3STEP4COO
Page 805 and 806: Answers A:37in their reduced form.
Page 807 and 808: Answers A:39D. Prokaryotic cells do
Page 809 and 810: Answers A:41cells that evolved. New
Page 811 and 812: Answers A:43ANSWER 16-14 Activation
Page 813 and 814: Answers A:45becomes localized by bi
Page 815 and 816: Answers A:47ANSWER 18-3 For multice
Page 817 and 818: Answers A:49overlapping interpolar
Page 819 and 820: Answers A:51large amounts of alcoho
Page 821 and 822: Answers A:53chromosome during a mei
Page 823 and 824: Answers A:55ANSWER 20-9A. False. Ga
Page 825 and 826: Glossaryacetyl CoAActivated carrier
Page 827 and 828: Glossary G:3Ca 2+ /calmodulin-depen
Page 829 and 830: Glossary G:5cyclic AMPSmall intrace
Page 831 and 832: Glossary G:7a chain of enzymatic re
Page 833 and 834: Glossary G:9homologousDescribes gen
Page 835 and 836: Glossary G:11membrane of a cell or
Page 837 and 838: Glossary G:13oxidative phosphorylat
Page 839 and 840: Glossary G:15as a molecular marker
Page 841 and 842: Glossary G:17stromaIn a chloroplast
Page 843 and 844: IndexNote: The index covers the tex
Page 845 and 846: IndexI:3BB lymphocytes/B cells 140F
Page 847 and 848: IndexI:5internal membranes 19, 365-
Page 849 and 850: IndexI:7cultured cell types 285cult
Page 851 and 852: IndexI:9endosomes 497-500, 507, 511
Page 853: IndexI:11familial hypertrophiccardi
Page 857 and 858: IndexI:15mitochondrial DNA 17, 245,
Page 859 and 860: IndexI:17oxaloacetate 110F, 142, 43
Page 861 and 862: IndexI:19pyrophosphate (PP i) 111,
Page 863 and 864: IndexI:21spindle poles 627F, 629F,
Page 865: IndexI:23water-splitting enzyme (ph
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Essential Cell Biology 5th edition

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