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Essential Cell Biology 5th edition

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656 CHAPTER 19 Sexual Reproduction and Genetics

germ-line cell. Mitosis, in contrast, produces two genetically identical

diploid nuclei. Figure 19−6 summarizes the molecular events that distinguish

these two types of division—differences we now discuss in greater

detail, beginning with the meiosis-specific pairing of maternal and paternal

chromosomes.

(A) MEIOSIS

(B) MITOSIS

MEIOSIS II MEIOSIS I MEIOTIC S PHASE

diploid

germ-line

cell

paternal

homolog

maternal

homolog

CHROMOSOME

DUPLICATION

DUPLICATED HOMOLOGS

PAIR AND RECOMBINE

DUPLICATED HOMOLOG PAIRS

LINE UP ON THE METAPHASE SPINDLE

SEPARATION OF HOMOLOGS

AT ANAPHASE OF MEIOSIS I

COMPLETION OF MEIOSIS I

SEPARATION OF

SISTER CHROMATIDS

AT ANAPHASE OF MEIOSIS II

CHROMOSOME

DUPLICATION

diploid

cell

DUPLICATED

CHROMOSOMES

LINE UP INDIVIDUALLY

ON THE METAPHASE

SPINDLE

SEPARATION OF

SISTER CHROMATIDS

AT ANAPHASE

MITOTIC S PHASE

M PHASE

nonidentical haploid cells

genetically identical diploid cells

Figure 19−6 Meiosis generates four nonidentical haploid nuclei, whereas mitosis produces two identical diploid nuclei. As in Figure

19−3, only one pair of homologous chromosomes is shown. (A) In meiosis, chromosome duplication is followed by two meiotic divisions

to produce haploid nuclei. Each diploid nucleus that enters meiosis therefore produces four haploid nuclei, which are then packaged into

haploid gametes by specialized forms of cytokinesis. (B) In mitosis, each diploid nucleus produces two diploid nuclei, which are packaged

by cytokinesis into two diploid cells. Although ECB5 mitosis e19.07/19.06

and meiosis II are similar processes that are usually accomplished within hours,

meiosis I can last days, months, or even years, because of the time required for homolog pairing before meiosis I.

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