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Essential Cell Biology 5th edition

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20 CHAPTER 1 Cells: The Fundamental Units of Life

Figure 1–22 The endoplasmic reticulum

produces many of the components of a

eukaryotic cell. (A) Schematic diagram of an

animal cell shows the endoplasmic reticulum

(ER) in green. (B) Electron micrograph of a

thin section of a mammalian pancreatic cell

shows a small part of the ER, of which there

are vast amounts in this cell type, which is

specialized for protein secretion. Note that

the ER is continuous with the membranes

of the nuclear envelope. The black particles

studding the region of the ER (and nuclear

envelope) shown here are ribosomes,

structures that translate RNAs into proteins.

Because of its appearance, ribosome-coated

ER is often called “rough ER” to distinguish

it from the “smooth ER,” which does not

have ribosomes bound to it. (B, courtesy of

Lelio Orci.)

(A)

nucleus nuclear envelope endoplasmic reticulum

(B)

ribosomes

1 µm

profusion of other organelles that are surrounded by single membranes

(see Figure 1–8A). Most of these structures are involved with the cell’s

ability to import raw materials and to export both useful substances and

waste products that are produced by the cell (a topic we discuss in detail

in Chapter 12).

The endoplasmic reticulum (ER) is an irregular maze of interconnected

spaces enclosed by a membrane (Figure 1–22). It is the site where most

cell-membrane components, as well as materials destined for export

from the cell, are made. This organelle is enormously enlarged in cells

that are specialized for ECB5 the secretion e1.21/1.22 of proteins. Stacks of flattened,

membrane-enclosed sacs constitute the Golgi apparatus (Figure 1–23),

nuclear

envelope

(A)

Figure 1–23 The Golgi apparatus is

composed of a stack of flattened,

membrane-enclosed discs. (A) Schematic

diagram of an animal cell with the Golgi

apparatus colored red. (B) More realistic

drawing of the Golgi apparatus. Some of

the vesicles seen nearby have pinched off

from the Golgi stack; others are destined to

fuse with it. Only one stack is shown here,

but several can be present in a cell.

(C) Electron micrograph that shows the

Golgi apparatus from a typical animal cell.

(C, courtesy of Brij L. Gupta.)

(B)

membraneenclosed

vesicles

Golgi apparatus

endoplasmic reticulum

(C)

1 µm

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