BREAST CYTOPATHOLOGY

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84 3. Benign and Borderline TumorsGupta RK, McHutchison AG, Dowle CS, Simpson JS: Fine-needleaspiration cytodiagnosis of breast masses in pregnant and lactatingwomen and its impact on management. Diagn Cytopathol1993, 9:156–159.Jain S, Kumar N, Sodhani P, Gupta S: Cytology of collagenousspherulosis of the breast: a diagnostic dilemma–report of threecases. Cytopathology 2002, 13:116–120.Jayaram G, Sthaneshwar P: Fine-needle aspiration cytology ofphyllodes tumors. Diagn Cytopathol 2002, 26:222–227.Lopez-Ferrer P, Jimenez-Heffernan JA, Vicandi B, Ortega L,Viguer JM: Fine needle aspiration cytology of breast fibroadenoma.A cytohistologic correlation study of 405 cases. Acta Cytol1999, 43:579–586.Ng WK: Adenomyoepithelioma of the breast. A review of threecases with reappraisal of the fine needle aspiration biopsy findings.Acta Cytol 2002, 46:317–324.Simsir A, Tsang P, Greenebaum E: Additional mimics of mucinousmammary carcinoma: fibroepithelial lesions. Am J Clin Pathol1998, 109:169–172.Simsir A, Waisman J, Cangiarella J: Fibroadenomas with atypia:causes of under- and overdiagnosis by aspiration biopsy. DiagnCytopathol 2001, 25:278–284.Stanley MW, Tani EM, Skoog L: Fine-needle aspiration of fibroadenomasof the breast with atypia: a spectrum including casesthat cytologically mimic carcinoma. Diagn Cytopathol 1990,6:375–382.
4Primary Malignant TumorsThis chapter focuses on primary malignant tumors of thebreast, including ductal, lobular, and special types of carcinomasand sarcomas.Ductal CarcinomaThis section focuses on the cytomorphology of in situ versusinvasive ductal carcinoma. It is emphasized that this representsa difficult area in cytology, and there is significant controversyas to whether it is possible to distinguish betweenthese two types of lesions using only cytomorphology.Ductal Carcinoma In SituClinical Features• Accounts for 10%–20% of mammographically detectedbreast carcinomas• Arises from terminal duct lobular unitsCytomorphologic Characteristics (Figures 4.1 to 4.9)• Smears are hypercellular, with sheets and cords of malignantcells.• Cells are crowded and enlarged. Nuclei are hyperchromaticwith occasional prominent nucleoli.85
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Breast Cytopathology
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Syed Z. Ali, MDDepartment of Pathol
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To my parentsGul Bano (late) and Ma
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viiiForewordthis volume to rejuvena
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xSeries Prefaceand form the framewo
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xiiPrefacecarefully selected high-r
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ContentsForeword by Dorothy L. Rose
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2 1. Introduction and Technical Asp
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10 1. Introduction and Technical As
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2Non-neoplastic andProliferative Le
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18 2. Non-neoplastic and Proliferat
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134 4. Primary Malignant TumorsClin
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136 4. Primary Malignant Tumorsdiag
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5Metastatic and SecondaryTumorsMeta
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140 5. Metastatic and Secondary Tum
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Figure 5.6. Metastatic small cell c
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BFigure 5.9. (B) Metastatic papilla
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154 6. Breast Ductal LavageTable 6.
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156 6. Breast Ductal LavageFigure 6
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162 6. Breast Ductal Lavagecarcinom
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164 6. Breast Ductal LavageKrishnam
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166 IndexApocrine carcinomain axill
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168 IndexDuctal carcinoma (cont.)fi
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170 IndexFine-needle aspiration, of
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172 IndexLung cancer, 138metastatic
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174 IndexPapilloma (cont.)invasive
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BREAST CYTOPATHOLOGY

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