BREAST CYTOPATHOLOGY

Inflammatory Myofibroblastic Tumor 51
Figure 2.36. Ductal carcinoma in male breast. Higher magnification
of the view in Figure 2.35 illustrates enlarged, pleomorphic, hyperchromatic
nuclei that are eccentrically placed in the cytoplasm,
imparting a plasmacytoid appearance. (Smear, Papanicolaou.)
Inflammatory Myofibroblastic Tumor
Inflammatory myofibroblastic tumor is an uncommon benign
tumorlike lesion that rarely occurs in the breast. The lesion
in the breast resembles its more common lung counterpart.
Fine-needle aspiration experience with inflammatory myofibroblastic
tumor in the breast is extremely limited.
Clinical Features
• Inflammatory myofibroblastic tumor has been observed in
most human organs.
• Clinically and on radiographic studies, it may simulate a
primary breast carcinoma.
• There are no systemic or constitutional symptoms of infection
noted.
• This is a rare lesion with many synonyms: inflammatory
pseudotumor, plasma cell granuloma, inflammatory myofibroblastic
tumor, fibroxanthoma, and so forth.