BREAST CYTOPATHOLOGY

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Figure 2.26. Lactational change. Hypercellular smear composed ofdistended breast lobules and abundant mixed inflammatory cells inthe background. These findings may appear worrisome leading to anerroneous diagnosis of atypia or cancer. (Smear, Papanicolaou.)Figure 2.27. Lactational change. Hypercellular smear that at highermagnification reveals partially disrupted lobules with enlargedhyperchromatic nuclei. Numerous naked lobular cell nuclei arepresent in the background in addition to lymphocytes, histiocytes,and numerous large lipid vacuoles. (Smear, Papanicolaou.)
Figure 2.28. Lactational change. A totally dissociated population ofnaked nuclei of lobular cells admixed with mixed inflammatory cellsis present. The presence of prominent nucleoli is unusual for lobularcarcinoma. The observer should have a much higher threshold forinterpreting atypia or cancer when dealing with a fine-needle aspiratefrom a young pregnant or lactating patient. (Smear, Papanicolaou.)Figure 2.29. Lactational change. Intact breast lobules distendedwith enlarged and hyperchromatic epithelial cells. Note the welldefinedmyoepithelial cell layer around these lobular structures. Acasual look at such aspirates may result in a false-positive diagnosisof lobular carcinoma. (Smear, Papanicolaou.)
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Breast Cytopathology
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Syed Z. Ali, MDDepartment of Pathol
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To my parentsGul Bano (late) and Ma
Page 8 and 9: viiiForewordthis volume to rejuvena
Page 10 and 11: xSeries Prefaceand form the framewo
Page 12 and 13: xiiPrefacecarefully selected high-r
Page 14 and 15: ContentsForeword by Dorothy L. Rose
Page 16 and 17: 2 1. Introduction and Technical Asp
Page 24 and 25: 10 1. Introduction and Technical As
Page 30 and 31: 2Non-neoplastic andProliferative Le
Page 32 and 33: 18 2. Non-neoplastic and Proliferat
Page 72 and 73: 58 3. Benign and Borderline TumorsC
Page 74 and 75: 60 3. Benign and Borderline TumorsF
Page 82 and 83: 68 3. Benign and Borderline Tumors
Page 98 and 99: 84 3. Benign and Borderline TumorsG
Page 100 and 101: 86 4. Primary Malignant Tumors• M
Page 102 and 103: 88 4. Primary Malignant TumorsFigur
Page 104 and 105: 90 4. Primary Malignant TumorsFigur
Page 106 and 107: 92 4. Primary Malignant TumorsHisto
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94 4. Primary Malignant TumorsFigur
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100 4. Primary Malignant TumorsFigu
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104 4. Primary Malignant Tumors•
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116 4. Primary Malignant TumorsPitf
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120 4. Primary Malignant TumorsInfl
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134 4. Primary Malignant TumorsClin
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136 4. Primary Malignant Tumorsdiag
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5Metastatic and SecondaryTumorsMeta
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140 5. Metastatic and Secondary Tum
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Figure 5.6. Metastatic small cell c
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BFigure 5.9. (B) Metastatic papilla
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154 6. Breast Ductal LavageTable 6.
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156 6. Breast Ductal LavageFigure 6
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162 6. Breast Ductal Lavagecarcinom
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164 6. Breast Ductal LavageKrishnam
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166 IndexApocrine carcinomain axill
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168 IndexDuctal carcinoma (cont.)fi
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170 IndexFine-needle aspiration, of
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172 IndexLung cancer, 138metastatic
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174 IndexPapilloma (cont.)invasive
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BREAST CYTOPATHOLOGY

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