BREAST CYTOPATHOLOGY

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40 2. Non-neoplastic and Proliferative LesionsFigure 2.21. Collagenous spherulosis. Cellular smear with hyperchromaticand crowded ductal epithelium. Two well-defined palegreen globular structures are present. (Smear, Papanicolaou.)Figure 2.22. Collagenous spherulosis. Papillary-like branchingcords of pale green cylindrical structures lined by proliferativeductal epithelium. Note the presence of stromal nuclei within thepale green substance, a feature often helpful in distinguishingcollagenous spherulosis from adenoid cystic carcinoma. (Smear,Papanicolaou.)
Collagenous Spherulosis 41Figure 2.23. Collagenous spherulosis. High magnification of ahyperchromatic crowded ductal epithelial fragment and juxtaposedpale green sharply defined globular structure. A morphologic distinctionfrom adenoid cystic carcinoma can be extremely difficult.(Smear, Papanicolaou.)Figure 2.24. Collagenous spherulosis. Higher magnification ofmetachromatic spherules mimicking adenoid cystic carcinoma. Thepresence of loosely cohesive ductal epithelial cells in the backgroundmakes it an extremely treacherous cytomorphologic interpretation.The presence of other associated findings in the case (such as papillomatosisand sclerosing adenosis) are often helpful for the diagnosisof collagenous spherulosis. (Smear, Diff-Quik.)
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Breast Cytopathology
Page 4 and 5: Syed Z. Ali, MDDepartment of Pathol
Page 6 and 7: To my parentsGul Bano (late) and Ma
Page 8 and 9: viiiForewordthis volume to rejuvena
Page 10 and 11: xSeries Prefaceand form the framewo
Page 12 and 13: xiiPrefacecarefully selected high-r
Page 14 and 15: ContentsForeword by Dorothy L. Rose
Page 16 and 17: 2 1. Introduction and Technical Asp
Page 24 and 25: 10 1. Introduction and Technical As
Page 30 and 31: 2Non-neoplastic andProliferative Le
Page 32 and 33: 18 2. Non-neoplastic and Proliferat
Page 58 and 59: Figure 2.26. Lactational change. Hy
Page 72 and 73: 58 3. Benign and Borderline TumorsC
Page 74 and 75: 60 3. Benign and Borderline TumorsF
Page 82 and 83: 68 3. Benign and Borderline Tumors
Page 98 and 99: 84 3. Benign and Borderline TumorsG
Page 100 and 101: 86 4. Primary Malignant Tumors• M
Page 102 and 103: 88 4. Primary Malignant TumorsFigur
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90 4. Primary Malignant TumorsFigur
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92 4. Primary Malignant TumorsHisto
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100 4. Primary Malignant TumorsFigu
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104 4. Primary Malignant Tumors•
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116 4. Primary Malignant TumorsPitf
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120 4. Primary Malignant TumorsInfl
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134 4. Primary Malignant TumorsClin
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136 4. Primary Malignant Tumorsdiag
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5Metastatic and SecondaryTumorsMeta
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140 5. Metastatic and Secondary Tum
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Figure 5.6. Metastatic small cell c
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BFigure 5.9. (B) Metastatic papilla
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154 6. Breast Ductal LavageTable 6.
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156 6. Breast Ductal LavageFigure 6
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162 6. Breast Ductal Lavagecarcinom
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164 6. Breast Ductal LavageKrishnam
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166 IndexApocrine carcinomain axill
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168 IndexDuctal carcinoma (cont.)fi
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170 IndexFine-needle aspiration, of
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172 IndexLung cancer, 138metastatic
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174 IndexPapilloma (cont.)invasive
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BREAST CYTOPATHOLOGY

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