BREAST CYTOPATHOLOGY

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BFigure 5.9. (B) Metastatic papillary serous carcinoma of theovary. Histologic section of the corresponding tumor shows a welldevelopedpapillary architecture with associated psammoma bodies.(Hematoxylin and eosin.)Figure 5.10. Metastatic medullary thyroid carcinoma. An irregularfragment of pleomorphic malignant cells with high nucleus to cytoplasmratios and prominent pleomorphism and anisonucleosis. Arare intranuclear inclusion is seen toward the center. There is nothingin this smear to suggest a medullary carcinoma diagnosis. Clinicalhistory and immunoperoxidase staining are crucial when dealingwith metastasis in the breast. (Smear, Diff-Quik.)
Metastatic Tumors 147Figure 5.11. Metastatic medullary thyroid carcinoma. Note the isolatedtumor cells with naked nuclei associated with fragments ofamorphous material consistent with amyloid (left). An immunostainfor calcitonin is strongly positive (right). (Smear, Papanicolaou.)Figure 5.12. Metastatic malignant melanoma. Isolated, singly placedpleomorphic malignant cells. Note prominent anisonucleosis andlong tapering cytoplasmic tails. Metastatic melanoma can closelymimic primary breast carcinoma and is not an uncommon metastasisto the breast. (Smear, Papanicolaou.)
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Breast Cytopathology
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Syed Z. Ali, MDDepartment of Pathol
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To my parentsGul Bano (late) and Ma
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viiiForewordthis volume to rejuvena
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xSeries Prefaceand form the framewo
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xiiPrefacecarefully selected high-r
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ContentsForeword by Dorothy L. Rose
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2 1. Introduction and Technical Asp
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10 1. Introduction and Technical As
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2Non-neoplastic andProliferative Le
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18 2. Non-neoplastic and Proliferat
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Figure 2.26. Lactational change. Hy
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58 3. Benign and Borderline TumorsC
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60 3. Benign and Borderline TumorsF
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68 3. Benign and Borderline Tumors
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84 3. Benign and Borderline TumorsG
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86 4. Primary Malignant Tumors• M
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88 4. Primary Malignant TumorsFigur
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92 4. Primary Malignant TumorsHisto
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Page 152 and 153: 5Metastatic and SecondaryTumorsMeta
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Page 158 and 159: Figure 5.6. Metastatic small cell c
Page 168 and 169: 154 6. Breast Ductal LavageTable 6.
Page 170 and 171: 156 6. Breast Ductal LavageFigure 6
Page 176 and 177: 162 6. Breast Ductal Lavagecarcinom
Page 178 and 179: 164 6. Breast Ductal LavageKrishnam
Page 180 and 181: 166 IndexApocrine carcinomain axill
Page 182 and 183: 168 IndexDuctal carcinoma (cont.)fi
Page 184 and 185: 170 IndexFine-needle aspiration, of
Page 186 and 187: 172 IndexLung cancer, 138metastatic
Page 188 and 189: 174 IndexPapilloma (cont.)invasive
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BREAST CYTOPATHOLOGY

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