BREAST CYTOPATHOLOGY

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Figure 5.6. Metastatic small cell carcinoma of the lung. Hypercellularsmear illustrating the characteristic neuroendocrine cytomorphology,that is, small round oval nuclei, fine dusty chromatin, nuclearmolding, nuclear crush artifacts, and numerous karyorrhectic nuclei.Distinction from a primary neuroendocrine carcinoma of the breastis not possible on morphology alone. (Smear, Papanicolaou.)Figure 5.7. Metastatic small cell carcinoma of the uterine cervix.This patient in advanced clinical stage presented with a breast mass.Cytomorphology as seen here looks concordant with a primary cervicaltumor. The smear is hypercellular with large nests of neuroendocrinecells, depicting high-grade morphology. Note prominentnuclear molding, lack of cytoplasm, and abundant karyorrhexis.(Smear, Diff-Quik.)
Metastatic Tumors 145Figure 5.8. Metastatic papillary serous carcinoma of the ovary. Thispatient had a known ovarian primary at the time of aspiration. Notethe papillary arrangement of this large tissue fragment. Cytomorphologicdistinction from primary breast papillary carcinoma is notpossible on morphology. (Smear, Papanicolaou.)AFigure 5.9. (A) Metastatic papillary serous carcinoma of the ovary.A single psammoma body is evident at 8 o’clock, along with a threedimensionaltissue fragment and abundant cystic debris. (Smear,Diff-Quik.)(Continued)
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Breast Cytopathology
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Syed Z. Ali, MDDepartment of Pathol
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To my parentsGul Bano (late) and Ma
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viiiForewordthis volume to rejuvena
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xSeries Prefaceand form the framewo
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xiiPrefacecarefully selected high-r
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ContentsForeword by Dorothy L. Rose
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2 1. Introduction and Technical Asp
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10 1. Introduction and Technical As
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2Non-neoplastic andProliferative Le
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18 2. Non-neoplastic and Proliferat
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Figure 2.26. Lactational change. Hy
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58 3. Benign and Borderline TumorsC
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60 3. Benign and Borderline TumorsF
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68 3. Benign and Borderline Tumors
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84 3. Benign and Borderline TumorsG
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86 4. Primary Malignant Tumors• M
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88 4. Primary Malignant TumorsFigur
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90 4. Primary Malignant TumorsFigur
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92 4. Primary Malignant TumorsHisto
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Page 152 and 153: 5Metastatic and SecondaryTumorsMeta
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Page 160 and 161: BFigure 5.9. (B) Metastatic papilla
Page 168 and 169: 154 6. Breast Ductal LavageTable 6.
Page 170 and 171: 156 6. Breast Ductal LavageFigure 6
Page 176 and 177: 162 6. Breast Ductal Lavagecarcinom
Page 178 and 179: 164 6. Breast Ductal LavageKrishnam
Page 180 and 181: 166 IndexApocrine carcinomain axill
Page 182 and 183: 168 IndexDuctal carcinoma (cont.)fi
Page 184 and 185: 170 IndexFine-needle aspiration, of
Page 186 and 187: 172 IndexLung cancer, 138metastatic
Page 188 and 189: 174 IndexPapilloma (cont.)invasive
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BREAST CYTOPATHOLOGY

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