BREAST CYTOPATHOLOGY

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108 4. Primary Malignant Tumors• Characteristically, abundant mucin that can be seengrosslyCytomorphologic Characteristics (Figures 4.26 to 4.29)• Abundant mucin• Gelatinous-appearing aspirates• Loosely cohesive, minimally pleomorphic epithelialfragments• Occasional single malignant cells• Cytoplasmic mucin vacuoles• Fragments of stroma with capillary vesselsPitfalls and Differential Diagnosis• Mucocele• Adenoid cystic carcinoma• Fibroadenoma showing myxoid changeFigure 4.26. Colloid carcinoma. Abundant mucin containing a fewloosely cohesive fragments of carcinoma cells. The appearance ofmalignant cells in colloid carcinoma is often low grade, requiringcareful exclusion of other benign entities with mucinous featuressuch as mucocele and fibroadenoma with abundant mucinousstroma. (Smear, Papanicolaou.)
Special Types of Breast Carcinomas 109Figure 4.27. Colloid carcinoma. Higher magnification shows looselydispersed malignant cells with large pleomorphic nuclei in a backgroundof abundant mucin. (Smear, Diff-Quik.)Figure 4.28. Colloid carcinoma. A small three-dimensional fragmentof ductal carcinoma floating in a mucinous background.(Smear, Papanicolaou.)
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Breast Cytopathology
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Syed Z. Ali, MDDepartment of Pathol
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To my parentsGul Bano (late) and Ma
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viiiForewordthis volume to rejuvena
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xSeries Prefaceand form the framewo
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xiiPrefacecarefully selected high-r
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ContentsForeword by Dorothy L. Rose
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2 1. Introduction and Technical Asp
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10 1. Introduction and Technical As
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2Non-neoplastic andProliferative Le
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18 2. Non-neoplastic and Proliferat
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Figure 2.26. Lactational change. Hy
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Page 72 and 73: 58 3. Benign and Borderline TumorsC
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Page 100 and 101: 86 4. Primary Malignant Tumors• M
Page 102 and 103: 88 4. Primary Malignant TumorsFigur
Page 106 and 107: 92 4. Primary Malignant TumorsHisto
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Page 118 and 119: 104 4. Primary Malignant Tumors•
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Page 148 and 149: 134 4. Primary Malignant TumorsClin
Page 150 and 151: 136 4. Primary Malignant Tumorsdiag
Page 152 and 153: 5Metastatic and SecondaryTumorsMeta
Page 154 and 155: 140 5. Metastatic and Secondary Tum
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Page 160 and 161: BFigure 5.9. (B) Metastatic papilla
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158 6. Breast Ductal LavageFigure 6
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160 6. Breast Ductal LavageFigure 6
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162 6. Breast Ductal Lavagecarcinom
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164 6. Breast Ductal LavageKrishnam
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166 IndexApocrine carcinomain axill
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168 IndexDuctal carcinoma (cont.)fi
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170 IndexFine-needle aspiration, of
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172 IndexLung cancer, 138metastatic
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174 IndexPapilloma (cont.)invasive
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BREAST CYTOPATHOLOGY

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