BREAST CYTOPATHOLOGY

102 4. Primary Malignant Tumors
Figure 4.24. Lobular carcinoma. A dense fragment of fibrous tissue
containing deceptively bland-appearing carcinoma cells. The cytopathologic
diagnosis of lobular carcinoma is often difficult because
of the absence of classic malignant features and inconspicuous infiltration
of malignant cells. (Smear, Papanicolaou.)
Figure 4.25. Lobular carcinoma. A higher magnification shows malignant
cells with high nucleus to cytoplasm ratios and barely visible
cytoplasm. A casual look at the aspirate may easily mistake such neoplastic
cells for benign lymphocytes. (Smear, Papanicolaou.)