13.05.2022 Views

BREAST CYTOPATHOLOGY

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Lobular Carcinoma 101

Figure 4.22. Lobular carcinoma. Higher magnification of a partially

intact neoplastic breast nodule tightly packed with small, round,

hyperchromatic nuclei. Few isolated carcinoma cells are seen in the

background, one with a well-defined cytoplasmic vacuole. (Smear,

Papanicolaou.)

Figure 4.23. Lobular carcinoma. Higher magnification shows single

and multiple cytoplasmic vacuoles containing targetoid mucin inclusions.

Cells have a signet ring morphology with a few mimicking

benign lymphocytes. (Smear, Papanicolaou.)

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