National Cancer Institute - NCI Division of Cancer Treatment and ...

tools allow searching by keyword or type
of cancer. The site also includes links to
other patient information materials.
ClinicalTrials.gov
http://clinicaltrials.gov
This Website provides regularly updated
information about federally and privately
supported clinical research in human volunteers.
It includes all diseases and gives
information about a trial’s purpose, who
may participate, locations, and phone
numbers for more details.
Community Clinical Oncology
Program
http://www.cancer.gov/prevention/ccop
The Community Clinical Oncology Program
(CCOP), administered by the NCI
Division of Cancer Prevention, is a comprehensive
clinical trial mechanism for
disseminating the latest cancer prevention
and treatment research findings to the
community level. A third of all patients
accrued to all NCI treatment trials and prevention
trials are enrolled at CCOP sites.
Created in 1983, the program works in
tandem with CTEP to enable patients and
physicians to participate in clinical trials at
61 major research centers in 34 states, the
District of Columbia, and Puerto Rico.
In 2005, 50 CCOPs and 13 minority-based
CCOPs across the country received funding
for participation in NCI-approved trials.
Altogether, the program comprises 3645
participating physicians and 415 participating
hospitals working on more than
300 active treatment trials and more than
70 active prevention and control trials.
CTEP’s Online Resources
for Investigators
http://ctep.cancer.gov/resources/
index.html
CTEP offers investigators online resources
for submitting data and reports, conducting
research, and accessing reference
materials:
■ Investigators’ Handbook (http://ctep.
cancer.gov/handbook/index.html):
Offers practical information for oncologists,
nurses, pharmacists, research
administrators, and data managers
about policies and procedures of DCTD
with respect to the clinical use of its
investigational agents, as well as
guidance on protocol writing and
submissions, reporting requirements,
and agent accountability
■ Common Terminology Criteria for Adverse
Events (CTCAE) v2.0 and v3.0: Standards
used to grade, assign attribution, and
report adverse effects experienced by
patients in clinical trials
■ Adverse Event Expedited Reporting System
(AdEERS): NCI’s Web-based system for
submitting expedited reports for serious
or unexpected events that occur during
a clinical trial
■ Common Data Elements (CDE) Dictionary:
A dictionary of terms that are used
when collecting patient information for
clinical trials or cancer care
■ Clinical Data Update System (CDUS):
The mechanism used when submitting
specified data for CTEP-approved
clinical trials
C A N C E R T H E R A P Y E V A L U A T I O N P R O G R A M ■ 93