National Cancer Institute - NCI Division of Cancer Treatment and ...

National Cancer Institute - NCI Division of Cancer Treatment and ... National Cancer Institute - NCI Division of Cancer Treatment and ...

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C A N C E R I M A G I N G P R O G R A M The role of imaging in cancer research is changing, and the Cancer Imaging Program is a catalyst for this transformation. The Cancer Imaging Program (CIP) of the Division of Cancer Treatment and Diagnosis (DCTD) is an innovative biomedical program that encourages collaboration among experts in basic, translational, and clinical research to advance the understanding of cancer imaging and to create better diagnosis and treatment options for patients. The role of imaging in cancer research is changing, and CIP is a catalyst for this transformation. Instead of the past focus on getting clearer and more detailed anatomic pictures of organs and tissues, the primary new thrust is on functional or molecular imaging, which visualizes the physiological, cellular, or molecular processes in living tissues as they take place. In the next decade, CIP-sponsored research will not only contribute to the basic understanding of various cancers, but will enhance imaging’s clinical role in noninvasive diagnosis, identification of disease subsets in patients, disease staging, and treatment monitoring. CIP unites in a team approach researchers from disciplines as diverse as radiology, bioengineering, biology, chemistry, computer science, and physics. The program encourages researchers to integrate and O V E R V I E W apply new imaging discoveries and developments to the study of cancer biology and to the clinical management of cancer and cancer risk. Originally formed as the Dr. Daniel C. Sullivan, Associate Director Daniel Sullivan, M.D., has had a distinguished career in the field of radiology, with more than 70 publications in peer-reviewed journals. His areas of clinical and research expertise are nuclear medicine and breast imaging, and he holds certifications in diagnostic and nuclear radiology from the American Board of Radiology. Dr. Sullivan joined the DCTD Cancer Imaging Program as its Associate Director in 1997. He currently heads the NCI-Food and Drug Administration (FDA) Interagency Oncology Task Force, the NCI-Centers for Medicare & Medicaid Services (CMS) Interagency Task Force Imaging Subcommittee, and the NCI Imaging Integration and Implementation (I2) Team. He is also a member of the NCI-CMS Interagency Task Force, the NCI Bioinformatics I2 Team, the NCI Translational Research Working Group, the NIH Multiple Principal Investigator Committee, the NIH Bioengineering Consortium, and the NIH Molecular Libraries and Molecular Imaging Roadmap Steering Committee. Dr. Sullivan is a member of the editorial board of the Journal of the Academy of Molecular Imaging. Dr. Sullivan received an A.B. in 1966 from Brown University and an M.D. in 1970 from the University of Vermont College of Medicine. From 1970 to 1977, he held several postdoctoral training and fellowship appointments at the Bethesda Naval Hospital and Yale-New Haven Hospital. From 1977 to 1997, he held faculty positions at Yale Medical School, Duke University Medical Center, and University of Pennsylvania Medical Center. In 1996, he was a member of the Project Hope Assessment Team that coordinated breast cancer detection and treatment in Poland. C A N C E R I M A G I N G P R O G R A M ■ 45

Diagnostic Imaging Program in 1996, CIP divides its staff and administered grants among four branches: ■ Diagnostic Imaging Branch ■ Molecular Imaging Branch ■ Image-Guided Intervention Branch ■ Imaging Technology Development Branch CIP supports and advises innovative developers in academia and private industry as they create the next generation of imaging technology, including molecular probes, optical technology devices, and new contrast agents. 46 ■ P R O G R A M A C C O M P L I S H M E N T S 2 0 0 6 ■ ■ ■ CIP supports and advises innovative developers in academia and private industry as they create the next generation of imaging technology, including molecular probes, optical technology devices, and new contrast agents. As part of its cutting-edge program, CIP plays a critical role in the activities of the National Institutes of Health (NIH) and the National Cancer Institute (NCI) related to emerging technologies, such as nanotechnology, proteomics, and high-throughput screening. In addition to funding projects in key areas, CIP supports researchers by providing pooled resources and developing protocols that encourage the sharing of data, samples, and results. CIP’s portfolio included 347 funded grants during fiscal year 2005. NCI Visuals Online, Terese Winslow, artist.

C A N C E R I M A G I N G P R O G R A M<br />

The role <strong>of</strong> imaging in cancer research is changing,<br />

<strong>and</strong> the <strong>Cancer</strong> Imaging Program is a catalyst for<br />

this transformation.<br />

The <strong>Cancer</strong> Imaging Program (CIP) <strong>of</strong><br />

the <strong>Division</strong> <strong>of</strong> <strong>Cancer</strong> <strong>Treatment</strong> <strong>and</strong><br />

Diagnosis (DCTD) is an innovative<br />

biomedical program that encourages<br />

collaboration among experts in basic,<br />

translational, <strong>and</strong> clinical research to<br />

advance the underst<strong>and</strong>ing <strong>of</strong> cancer<br />

imaging <strong>and</strong> to create better diagnosis<br />

<strong>and</strong> treatment options for patients.<br />

The role <strong>of</strong> imaging in cancer research<br />

is changing, <strong>and</strong> CIP is a catalyst for this<br />

transformation. Instead <strong>of</strong> the past focus<br />

on getting clearer <strong>and</strong> more detailed<br />

anatomic pictures <strong>of</strong> organs <strong>and</strong> tissues,<br />

the primary new thrust is on functional<br />

or molecular imaging, which visualizes<br />

the physiological, cellular, or molecular<br />

processes in living tissues as they take<br />

place. In the next decade, CIP-sponsored<br />

research will not only contribute to the<br />

basic underst<strong>and</strong>ing <strong>of</strong> various cancers,<br />

but will enhance imaging’s clinical role<br />

in noninvasive diagnosis, identification<br />

<strong>of</strong> disease subsets in patients, disease<br />

staging, <strong>and</strong> treatment monitoring.<br />

CIP unites in a team approach researchers<br />

from disciplines as diverse as radiology,<br />

bioengineering, biology, chemistry, computer<br />

science, <strong>and</strong> physics. The program<br />

encourages researchers to integrate <strong>and</strong><br />

O V E R V I E W<br />

apply new imaging discoveries <strong>and</strong> developments<br />

to the study <strong>of</strong> cancer biology<br />

<strong>and</strong> to the clinical management <strong>of</strong> cancer<br />

<strong>and</strong> cancer risk. Originally formed as the<br />

Dr. Daniel C. Sullivan, Associate Director<br />

Daniel Sullivan, M.D., has had a distinguished career in<br />

the field <strong>of</strong> radiology, with more than 70 publications in<br />

peer-reviewed journals. His areas <strong>of</strong> clinical <strong>and</strong> research<br />

expertise are nuclear medicine <strong>and</strong> breast imaging, <strong>and</strong><br />

he holds certifications in diagnostic <strong>and</strong> nuclear radiology<br />

from the American Board <strong>of</strong> Radiology.<br />

Dr. Sullivan joined the DCTD <strong>Cancer</strong> Imaging Program<br />

as its Associate Director in 1997. He currently heads the<br />

<strong>NCI</strong>-Food <strong>and</strong> Drug Administration (FDA) Interagency<br />

Oncology Task Force, the <strong>NCI</strong>-Centers for Medicare & Medicaid Services (CMS)<br />

Interagency Task Force Imaging Subcommittee, <strong>and</strong> the <strong>NCI</strong> Imaging Integration<br />

<strong>and</strong> Implementation (I2) Team. He is also a member <strong>of</strong> the <strong>NCI</strong>-CMS Interagency<br />

Task Force, the <strong>NCI</strong> Bioinformatics I2 Team, the <strong>NCI</strong> Translational Research Working<br />

Group, the NIH Multiple Principal Investigator Committee, the NIH Bioengineering<br />

Consortium, <strong>and</strong> the NIH Molecular Libraries <strong>and</strong> Molecular Imaging<br />

Roadmap Steering Committee. Dr. Sullivan is a member <strong>of</strong> the editorial board<br />

<strong>of</strong> the Journal <strong>of</strong> the Academy <strong>of</strong> Molecular Imaging.<br />

Dr. Sullivan received an A.B. in 1966 from Brown University <strong>and</strong> an M.D. in 1970<br />

from the University <strong>of</strong> Vermont College <strong>of</strong> Medicine. From 1970 to 1977, he<br />

held several postdoctoral training <strong>and</strong> fellowship appointments at the Bethesda<br />

Naval Hospital <strong>and</strong> Yale-New Haven Hospital. From 1977 to 1997, he held faculty<br />

positions at Yale Medical School, Duke University Medical Center, <strong>and</strong> University<br />

<strong>of</strong> Pennsylvania Medical Center. In 1996, he was a member <strong>of</strong> the Project Hope<br />

Assessment Team that coordinated breast cancer detection <strong>and</strong> treatment<br />

in Pol<strong>and</strong>.<br />

C A N C E R I M A G I N G P R O G R A M ■ 45

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