National Cancer Institute - NCI Division of Cancer Treatment and ...

■ Cooperative Human Tissue
Network (CHTN)
http://www-chtn.ims.nci.nih.gov
CHTN provides biomedical researchers
with access to human tissues. Six
regional member institutions coordinate
the collection and distribution of tissues
across the United States and Canada.
In addition to normal, benign, and
malignant tissues, the resource offers
tissues from patients with other diseases
such as ulcerative colitis. Trained personnel
coordinate the retrieval, preservation,
and delivery of specimens obtained
from surgical resections and autopsies.
Since its establishment in 1987, CHTN
has provided more than 500,000
high-quality specimens from a wide
variety of organ sites to more than
1000 investigators.
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■ The NCI Clinical Trials Cooperative
Groups have banked tumor specimens
from large numbers of uniformly
treated cancer patients with a variety
of malignancies. Each group has a
review process for research proposals.
If proposals receive favorable reviews,
specimens with clinical, treatment, and
outcome data can be made available
to researchers through collaborative
arrangements. These banked specimens
are most useful for clinical correlative
studies on uniformly treated patient
populations. Interested investigators
may visit the NCI Specimen Resource
Locator Website (http://pluto3.nci.nih.
gov/tissue/default.htm) or contact the
Tissue Expediter at tissexp@mail.nih.gov.
Reporting Studies of Tumor Markers
http://www.cancerdiagnosis.nci.nih.gov/
assessment/progress/remark.html
The REMARK guidelines resulted from
a collaboration of a PACCT strategy
group and an NCI-EORTC working group.
REMARK includes information that should
be reported in all publications about
tumor markers. These recommendations
were published simultaneously in British
Journal of Cancer, European Journal of
Cancer, Journal of Clinical Oncology, Journal
of the National Cancer Institute, and Nature
Clinical Practice Oncology.
The recommendations are available on
the CDP Website to help the research
community and members of journal
editorial boards ensure that more
complete information is included in
publications about prognostic markers.