Emotional inteligence
336/661that are conjured by the mind, not real dangers we needto confront. Repeated bouts of anxiety signal high levelsof stress. The woman whose constant worrying primesher gastrointestinal trouble is a textbook example ofhow anxiety and stress exacerbate medical problems.In a 1993 review in the Archives of Internal Medicineof extensive research on the stress-disease link, Yalepsychologist Bruce McEwen noted a broad spectrum ofeffects: compromising immune function to the pointthat it can speed the metastasis of cancer; increasingvulnerability to viral infections; exacerbating plaqueformation leading to atherosclerosis and blood clottingleading to myocardial infarction; accelerating the onsetof Type I diabetes and the course of Type II diabetes;and worsening or triggering an asthma attack. 20 Stresscan also lead to ulceration of the gastrointestinal tract,triggering symptoms in ulcerative colitis and in inflammatorybowel disease. The brain itself is susceptible tothe long-term effects of sustained stress, including damageto the hippocampus, and so to memory. In general,says McEwen, "evidence is mounting that the nervoussystem is subject to 'wear and tear' as a result of stressfulexperiences." 21Particularly compelling evidence for the medical impactfrom distress has come from studies with infectiousdiseases such as colds, the flu, and herpes. We are
337/661continually exposed to such viruses, but ordinarily ourimmune system fights them off—except that under emotionalstress those defenses more often fail. In experimentsin which the robustness of the immune systemhas been assayed directly, stress and anxiety have beenfound to weaken it, but in most such results it is unclearwhether the range of immune weakening is of clinicalsignificance—that is, great enough to open the way todisease. 22 For that reason stronger scientific links ofstress and anxiety to medical vulnerability come fromprospective studies: those that start with healthy peopleand monitor first a heightening of distress followed by aweakening of the immune system and the onset ofillness.In one of the most scientifically compelling studies,Sheldon Cohen, a psychologist at Carnegie-MellonUniversity, working with scientists at a specialized coldsresearch unit in Sheffield, England, carefully assessedhow much stress people were feeling in their lives, andthen systematically exposed them to a cold virus. Noteveryone so exposed actually comes down with a cold; arobust immune system can—and constantly does—resistthe cold virus. Cohen found that the more stress in theirlives, the more likely people were to catch cold. Amongthose with little stress, 27 percent came down with acold after being exposed to the virus; among those with
- Page 286 and 287: yourself. Another is to take respon
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- Page 304 and 305: budge the biases of those employees
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337/661
continually exposed to such viruses, but ordinarily our
immune system fights them off—except that under emotional
stress those defenses more often fail. In experiments
in which the robustness of the immune system
has been assayed directly, stress and anxiety have been
found to weaken it, but in most such results it is unclear
whether the range of immune weakening is of clinical
significance—that is, great enough to open the way to
disease. 22 For that reason stronger scientific links of
stress and anxiety to medical vulnerability come from
prospective studies: those that start with healthy people
and monitor first a heightening of distress followed by a
weakening of the immune system and the onset of
illness.
In one of the most scientifically compelling studies,
Sheldon Cohen, a psychologist at Carnegie-Mellon
University, working with scientists at a specialized colds
research unit in Sheffield, England, carefully assessed
how much stress people were feeling in their lives, and
then systematically exposed them to a cold virus. Not
everyone so exposed actually comes down with a cold; a
robust immune system can—and constantly does—resist
the cold virus. Cohen found that the more stress in their
lives, the more likely people were to catch cold. Among
those with little stress, 27 percent came down with a
cold after being exposed to the virus; among those with