Physical_Activity_Guidelines
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Figure 2-1. Relationship of Moderate-to-Vigorous Physical Activity
to All-Cause Mortality
1.1
Hazard Ratio of Mortality
1
0.9
0.8
0.7
0.6
0.5
No lower threshold for benefit
Steep early slope
About 70% of benefit reached
by 8.25 MET-hours per week
No obvious best amount
150–300 minutes of
moderate physical activity
0 5 10 15 20 25 30
Leisure Time Physical Activity
(MET-hours per Week)
No evidence of increased risk at high end
Source: Adapted from data found in Moore SC, Patel AV, Matthews CE. Leisure time physical activity of moderate to vigorous intensity
and mortality: a large pooled cohort analysis. PLoS Med. 2012;9(11):e1001335. doi:10.1371/journal.pmed.1001335.
All adults can gain this health benefit of physical activity, no matter their age, sex, race, or ethnicity. Physically
active people with all body weights (normal weight, overweight, obesity) also have lower risk of all-cause
mortality than do inactive people.
Cardiorespiratory Health
The benefits of physical activity on cardiorespiratory health are some of the most extensively documented of
all the health benefits. Cardiorespiratory health involves the health of the heart, lungs, and blood vessels.
Heart disease and stroke are two of the leading causes of death in the United States. Risk factors that
increase the likelihood of cardiovascular diseases include smoking, hypertension, type 2 diabetes, and high
levels of certain blood lipids (such as low-density lipoprotein [LDL] cholesterol). Low cardiorespiratory fitness
also is a risk factor for heart disease.
Physical activity strongly reduces both the risk of dying from cardiovascular disease and the risk of developing
cardiovascular disease, including heart attack, stroke, and heart failure. Regularly active adults have lower
rates of heart disease and stroke and have lower blood pressure, better blood lipid profiles, and better physical
fitness. Significant reductions in risk of cardiovascular disease occur at activity levels equivalent to 150 minutes
a week of moderate-intensity physical activity. As with all-cause mortality, benefits begin with less than 150
minutes a week, and strong evidence shows that greater amounts of physical activity result in even further
reductions in risk of cardiovascular disease.
Chapter 2. Physical Activity and Health 35