Nina Wettschureck and Stefan Offermanns - Physiological Reviews
Nina Wettschureck and Stefan Offermanns - Physiological Reviews
Nina Wettschureck and Stefan Offermanns - Physiological Reviews
Create successful ePaper yourself
Turn your PDF publications into a flip-book with our unique Google optimized e-Paper software.
Local calcium release in dendritic spines required for long-term<br />
synaptic depression. Neuron 28: 233–244, 2000.<br />
453. Miyata M, Kim HT, Hashimoto K, Lee TK, Cho SY, Jiang H, Wu<br />
Y, Jun K, Wu D, Kano M, <strong>and</strong> Shin HS. Deficient long-term<br />
synaptic depression in the rostral cerebellum correlated with impaired<br />
motor learning in phospholipase C beta4 mutant mice. Eur<br />
J Neurosci 13: 1945–1954, 2001.<br />
454. Mochly-Rosen D, Wu G, Hahn H, Osinska H, Liron T, Lorenz<br />
JN, Yatani A, Robbins J, <strong>and</strong> Dorn GW II. Cardiotrophic effects<br />
of protein kinase C epsilon: analysis by in vivo modulation of<br />
PKCepsilon translocation. Circ Res 86: 1173–1179, 2000.<br />
455. Moers A, Niesw<strong>and</strong>t B, Massberg S, <strong>Wettschureck</strong> N, Gruner<br />
S, Konrad I, Schulte V, Aktas B, Gratacap MP, Simon MI,<br />
Gawaz M, <strong>and</strong> <strong>Offermanns</strong> S. G13 is an essential mediator of<br />
platelet activation in hemostasis <strong>and</strong> thrombosis. Nat Med 9: 1418–<br />
1422, 2003.<br />
456. Moers A, <strong>Wettschureck</strong> N, Gruner S, Niesw<strong>and</strong>t B, <strong>and</strong> <strong>Offermanns</strong><br />
S. Unresponsiveness of platelets lacking both G�q <strong>and</strong><br />
G�13: implications for collagen-induced platelet activation. J Biol<br />
Chem 279: 45354–45359, 2004.<br />
457. Mombaerts P. Genes <strong>and</strong> lig<strong>and</strong>s for odorant, vomeronasal <strong>and</strong><br />
taste receptors. Nat Rev Neurosci 5: 263–278, 2004.<br />
458. Montaner S, Sodhi A, Molinolo A, Bugge TH, Sawai ET, He Y,<br />
Li Y, Ray PE, <strong>and</strong> Gutkind JS. Endothelial infection with KSHV<br />
genes in vivo reveals that vGPCR initiates Kaposi’s sarcomagenesis<br />
<strong>and</strong> can promote the tumorigenic potential of viral latent genes.<br />
Cancer Cell 3: 23–36, 2003.<br />
459. Moxham CM, Hod Y, <strong>and</strong> Malbon CC. Gi alpha 2 mediates the<br />
inhibitory regulation of adenylylcyclase in vivo: analysis in transgenic<br />
mice with Gi alpha 2 suppressed by inducible antisense RNA.<br />
Dev Genet 14: 266–273, 1993.<br />
460. Moxham CM, Hod Y, <strong>and</strong> Malbon CC. Induction of G alpha<br />
i2-specific antisense RNA in vivo inhibits neonatal growth. Science<br />
260: 991–995, 1993.<br />
461. Moxham CM <strong>and</strong> Malbon CC. Insulin action impaired by deficiency<br />
of the G protein subunit G ialpha2. Nature 379: 840–844,<br />
1996.<br />
462. Muca C <strong>and</strong> Vallar L. Expression of mutationally activated G<br />
alpha s stimulates growth <strong>and</strong> differentiation of thyroid FRTL5<br />
cells. Oncogene 9: 3647–3653, 1994.<br />
463. Mueller KL, Hoon MA, Erlenbach I, Ch<strong>and</strong>rashekar J, Zuker<br />
CS, <strong>and</strong> Ryba NJ. The receptors <strong>and</strong> coding logic for bitter taste.<br />
Nature 434: 225–229, 2005.<br />
464. Munoz JJ <strong>and</strong> Mackay IR. Production of experimental allergic<br />
encephalomyelitis with the aid of pertussigen in mouse strains<br />
considered genetically resistant. J Neuroimmunol 7: 91–96, 1984.<br />
465. Murakami N, Yokomizo T, Okuno T, <strong>and</strong> Shimizu T. G2A is a<br />
proton-sensing G protein-coupled receptor antagonized by lysophosphatidylcholine.<br />
J Biol Chem 279: 42484–42491, 2004.<br />
466. Murphy PM. International Union of Pharmacology. XXX. Update<br />
on chemokine receptor nomenclature. Pharmacol Rev 54: 227–229,<br />
2002.<br />
467. Murphy PM, Baggiolini M, Charo IF, Hebert CA, Horuk R,<br />
Matsushima K, Miller LH, Oppenheim JJ, <strong>and</strong> Power CA.<br />
International union of pharmacology. XXII. Nomenclature for chemokine<br />
receptors. Pharmacol Rev 52: 145–176, 2000.<br />
468. Nagata K, Ye C, Jain M, Milstone DS, Liao R, <strong>and</strong> Mortensen<br />
RM. Galpha(i2) but not Galpha(i3) is required for muscarinic inhibition<br />
of contractility <strong>and</strong> calcium currents in adult cardiomyocytes.<br />
Circ Res 87: 903–909, 2000.<br />
469. Nakano K, Suga S, Takeo T, Ogawa Y, Suda T, Kanno T, <strong>and</strong><br />
Wakui M. Intracellular Ca(2�) modulation of ATP-sensitive K(�)<br />
channel activity in acetylcholine-induced activation of rat pancreatic<br />
beta-cells. Endocrinology 143: 569–576, 2002.<br />
470. Narumiya S, Sugimoto Y, <strong>and</strong> Ushikubi F. Prostanoid receptors:<br />
structures, properties, <strong>and</strong> functions. Physiol Rev 79: 1193–1226,<br />
1999.<br />
471. Nathans J. The evolution <strong>and</strong> physiology of human color vision:<br />
insights from molecular genetic studies of visual pigments. Neuron<br />
24: 299–312, 1999.<br />
472. Navarro VM, Castellano JM, Fern<strong>and</strong>ez-Fern<strong>and</strong>ez R, Barreiro<br />
ML, Roa J, Sanchez-Criado JE, Aguilar E, Dieguez C,<br />
Pinilla L, <strong>and</strong> Tena-Sempere M. Developmental <strong>and</strong> hormonally<br />
CELLULAR FUNCTIONS OF G PROTEINS 1197<br />
Physiol Rev • VOL 85 • OCTOBER 2005 • www.prv.org<br />
regulated messenger ribonucleic acid expression of KiSS-1 <strong>and</strong> its<br />
putative receptor, GPR54, in rat hypothalamus <strong>and</strong> potent luteinizing<br />
hormone-releasing activity of KiSS-1 peptide. Endocrinology<br />
145: 4565–4574, 2004.<br />
473. Nebigil CG, Choi DS, Dierich A, Hickel P, Le Meur M, Messaddeq<br />
N, Launay JM, <strong>and</strong> Maroteaux L. Serotonin 2B receptor<br />
is required for heart development. Proc Natl Acad Sci USA 97:<br />
9508–9513, 2000.<br />
474. Nebigil CG, Jaffre F, Messaddeq N, Hickel P, Monassier L,<br />
Launay JM, <strong>and</strong> Maroteaux L. Overexpression of the serotonin<br />
5-HT 2B receptor in heart leads to abnormal mitochondrial function<br />
<strong>and</strong> cardiac hypertrophy. Circulation 107: 3223–3229, 2003.<br />
475. Neer EJ. Heterotrimeric G proteins: organizers of transmembrane<br />
signals. Cell 80: 249–257, 1995.<br />
476. Nel AE, V<strong>and</strong>enplas M, Wooten MM, Cooper R, V<strong>and</strong>enplas S,<br />
Rheeder A, <strong>and</strong> Daniels J. Cholera toxin partially inhibits the<br />
T-cell response to phytohaemagglutinin through the ADP-ribosylation<br />
of a 45 kDa membrane protein. Biochem J 256: 383–390, 1988.<br />
477. Nelson G, Hoon MA, Ch<strong>and</strong>rashekar J, Zhang Y, Ryba NJ, <strong>and</strong><br />
Zuker CS. Mammalian sweet taste receptors. Cell 106: 381–390,<br />
2001.<br />
478. Nemeth EF <strong>and</strong> Scarpa A. Rapid mobilization of cellular Ca 2� in<br />
bovine parathyroid cells evoked by extracellular divalent cations.<br />
Evidence for a cell surface calcium receptor. J Biol Chem 262:<br />
5188–5196, 1987.<br />
479. Neptune ER <strong>and</strong> Bourne HR. Receptors induce chemotaxis by<br />
releasing the betagamma subunit of Gi, not by activating Gq or Gs.<br />
Proc Natl Acad Sci USA 94: 14489–14494, 1997.<br />
480. Neptune ER, Iiri T, <strong>and</strong> Bourne HR. Galphai is not required for<br />
chemotaxis mediated by Gi-coupled receptors. J Biol Chem 274:<br />
2824–2828, 1999.<br />
481. Neubig RR <strong>and</strong> Siderovski DP. Regulators of G protein signalling<br />
as new central nervous system drug targets. Nat Rev Drug Discov<br />
1: 187–197, 2002.<br />
482. Neumann J, Schmitz W, Scholz H, von Meyerinck L, Doring V,<br />
<strong>and</strong> Kalmar P. Increase in myocardial Gi-proteins in heart failure.<br />
Lancet 2: 936–937, 1988.<br />
483. Niesw<strong>and</strong>t B, Schulte V, Zywietz A, Gratacap MP, <strong>and</strong> <strong>Offermanns</strong><br />
S. Costimulation of Gi- <strong>and</strong> G12/G13-mediated signaling<br />
pathways induces integrin alpha IIbbeta 3 activation in platelets.<br />
J Biol Chem 277: 39493–39498, 2002.<br />
484. Niggli V. Signaling to migration in neutrophils: importance of<br />
localized pathways. Int J Biochem Cell Biol 35: 1619–1638, 2003.<br />
485. Niu J, Vaiskunaite R, Suzuki N, Kozasa T, Carr DW, Dulin N,<br />
<strong>and</strong> Voyno-Yasenetskaya TA. Interaction of heterotrimeric G13<br />
protein with an A-kinase-anchoring protein 110 (AKAP110) mediates<br />
cAMP-independent PKA activation. Curr Biol 11: 1686–1690,<br />
2001.<br />
486. Norlin EM, Gussing F, <strong>and</strong> Berghard A. Vomeronasal phenotype<br />
<strong>and</strong> behavioral alterations in G alpha i2 mutant mice. Curr Biol 13:<br />
1214–1219, 2003.<br />
487. Oak JN <strong>and</strong> Van Tol Dopamine HHM. Dopamine system. In:<br />
Encyclopedic Reference of Molecular Pharmacology, edited by <strong>Offermanns</strong><br />
S <strong>and</strong> Rosenthal W. Berlin: Springer, 2004, p. 310–315.<br />
488. Ofer W. G protein regulation of channels. In: H<strong>and</strong>book of Cell<br />
Signaling, edited by Bradshaw RA <strong>and</strong> Dennis EA. Boston, MA:<br />
Academic Press, 2004, p. 667–670.<br />
489. <strong>Offermanns</strong> S, Hashimoto K, Watanabe M, Sun W, Kurihara<br />
H, Thompson RF, Inoue Y, Kano M, <strong>and</strong> Simon MI. Impaired<br />
motor coordination <strong>and</strong> persistent multiple climbing fiber innervation<br />
of cerebellar Purkinje cells in mice lacking Galphaq. Proc Natl<br />
Acad Sci USA 94: 14089–14094, 1997.<br />
490. <strong>Offermanns</strong> S, Heiler E, Spicher K, <strong>and</strong> Schultz G. Gq <strong>and</strong> G11<br />
are concurrently activated by bombesin <strong>and</strong> vasopressin in Swiss<br />
3T3 cells. FEBS Lett 349: 201–204, 1994.<br />
491. <strong>Offermanns</strong> S, Hu YH, <strong>and</strong> Simon MI. Galpha12 <strong>and</strong> Galpha13<br />
are phosphorylated during platelet activation. J Biol Chem 271:<br />
26044–26048, 1996.<br />
492. <strong>Offermanns</strong> S, Laugwitz KL, Spicher K, <strong>and</strong> Schultz G. G<br />
proteins of the G12 family are activated via thromboxane A 2 <strong>and</strong><br />
thrombin receptors in human platelets. Proc Natl Acad Sci USA 91:<br />
504–508, 1994.