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Nina Wettschureck and Stefan Offermanns - Physiological Reviews

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1194 NINA WETTSCHURECK AND STEFAN OFFERMANNS<br />

329. Kehlenbach RH, Matthey J, <strong>and</strong> Huttner WB. XL alpha s is a<br />

new type of G protein. Nature 372: 804–809, 1994.<br />

330. Keverne EB. The vomeronasal organ. Science 286: 716–720, 1999.<br />

331. Keys JR, Greene EA, Koch WJ, <strong>and</strong> Eckhart AD. Gq-coupled<br />

receptor agonists mediate cardiac hypertrophy via the vasculature.<br />

Hypertension 40: 660–666, 2002.<br />

332. Kieffer TJ. GIP or not GIP? That is the question. Trends Pharmacol<br />

Sci 24: 110–112, 2003.<br />

333. Kifor O, Diaz R, Butters R, <strong>and</strong> Brown EM. The Ca 2� -sensing<br />

receptor (CaR) activates phospholipases C, A 2, <strong>and</strong> D in bovine<br />

parathyroid <strong>and</strong> CaR-transfected, human embryonic kidney<br />

(HEK293) cells. J Bone Miner Res 12: 715–725, 1997.<br />

334. Kim IS, Kim ER, Nam HJ, Chin MO, Moon YH, Oh MR, Yeo UC,<br />

Song SM, Kim JS, Uhm MR, Beck NS, <strong>and</strong> Jin DK. Activating<br />

mutation of GS alpha in McCune-Albright syndrome causes skin<br />

pigmentation by tyrosinase gene activation on affected melanocytes.<br />

Horm Res 52: 235–240, 1999.<br />

335. Kishi K, Hayashi H, Wang L, Kamohara S, Tamaoka K,<br />

Shimizu T, Ushikubi F, Narumiya S, <strong>and</strong> Ebina Y. Gq-coupled<br />

receptors transmit the signal for GLUT4 translocation via an insulin-independent<br />

pathway. J Biol Chem 271: 26561–26568, 1996.<br />

336. Kishi K, Muromoto N, Nakaya Y, Miyata I, Hagi A, Hayashi H,<br />

<strong>and</strong> Ebina Y. Bradykinin directly triggers GLUT4 translocation via<br />

an insulin-independent pathway. Diabetes 47: 550–558, 1998.<br />

337. Klages B, Br<strong>and</strong>t U, Simon MI, Schultz G, <strong>and</strong> <strong>Offermanns</strong> S.<br />

Activation of G12/G13 results in shape change <strong>and</strong> Rho/Rho-kinasemediated<br />

myosin light chain phosphorylation in mouse platelets.<br />

J Cell Biol 144: 745–754, 1999.<br />

338. Klemke M, Kehlenbach RH, <strong>and</strong> Huttner WB. Two overlapping<br />

reading frames in a single exon encode interacting proteins–a novel<br />

way of gene usage. EMBO J 20: 3849–3860, 2001.<br />

339. Klemke M, Pasolli HA, Kehlenbach RH, <strong>Offermanns</strong> S,<br />

Schultz G, <strong>and</strong> Huttner WB. Characterization of the extra-large G<br />

protein alpha-subunit XLalphas. II. Signal transduction properties.<br />

J Biol Chem 275: 33633–33640, 2000.<br />

340. Kleppisch T, Voigt V, Allmann R, <strong>and</strong> <strong>Offermanns</strong> S. G(alpha)qdeficient<br />

mice lack metabotropic glutamate receptor-dependent<br />

long-term depression but show normal long-term potentiation in<br />

the hippocampal CA1 region. J Neurosci 21: 4943–4948, 2001.<br />

341. Knowlton KU, Michel MC, Itani M, Shubeita HE, Ishihara K,<br />

Brown JH, <strong>and</strong> Chien KR. The alpha 1A-adrenergic receptor<br />

subtype mediates biochemical, molecular, <strong>and</strong> morphologic features<br />

of cultured myocardial cell hypertrophy. J Biol Chem 268:<br />

15374–15380, 1993.<br />

342. Kojima M, Hosoda H, Date Y, Nakazato M, Matsuo H, <strong>and</strong><br />

Kangawa K. Ghrelin is a growth-hormone-releasing acylated peptide<br />

from stomach. Nature 402: 656–660, 1999.<br />

343. Korbonits M, Goldstone AP, Gueorguiev M, <strong>and</strong> Grossman<br />

AB. Ghrelin—a hormone with multiple functions. Front Neuroendocrinol<br />

25: 27–68, 2004.<br />

344. Kosugi S, Okajima F, Ban T, Hidaka A, Shenker A, <strong>and</strong> Kohn<br />

LD. Substitutions of different regions of the third cytoplasmic loop<br />

of the thyrotropin (TSH) receptor have selective effects on constitutive,<br />

TSH-, <strong>and</strong> TSH receptor autoantibody-stimulated phosphoinositide<br />

<strong>and</strong> 3�,5�-cyclic adenosine monophosphate signal generation.<br />

Mol Endocrinol 7: 1009–1020, 1993.<br />

345. Kotani M, Detheux M, V<strong>and</strong>enbogaerde A, Communi D,<br />

V<strong>and</strong>erwinden JM, Le Poul E, Brezillon S, Tyldesley R,<br />

Suarez-Huerta N, V<strong>and</strong>eput F, Blanpain C, Schiffmann SN,<br />

Vassart G, <strong>and</strong> Parmentier M. The metastasis suppressor gene<br />

KiSS-1 encodes kisspeptins, the natural lig<strong>and</strong>s of the orphan G<br />

protein-coupled receptor GPR54. J Biol Chem 276: 34631–34636,<br />

2001.<br />

346. Kotarsky K, Nilsson NE, Flodgren E, Owman C, <strong>and</strong> Olde B. A<br />

human cell surface receptor activated by free fatty acids <strong>and</strong><br />

thiazolidinedione drugs. Biochem Biophys Res Commun 301: 406–<br />

410, 2003.<br />

347. Kozasa T. Mechanism of beta-gamma effector interaction. In:<br />

H<strong>and</strong>book of Cell Signaling, edited by Bradshaw RA <strong>and</strong> Dennis<br />

EA. Boston, MA: Academic, 2004, p. 639–643.<br />

348. Kozasa T, Jiang X, Hart MJ, Sternweis PM, Singer WD, Gilman<br />

AG, Bollag G, <strong>and</strong> Sternweis PC. p115 RhoGEF, a GTPase<br />

Physiol Rev • VOL 85 • OCTOBER 2005 • www.prv.org<br />

activating protein for Galpha12 <strong>and</strong> Galpha13. Science 280: 2109–<br />

2111, 1998.<br />

349. Krapivinsky G, Krapivinsky L, Wickman K, <strong>and</strong> Clapham DE.<br />

G beta gamma binds directly to the G protein-gated K � channel,<br />

IKACh. J Biol Chem 270: 29059–29062, 1995.<br />

350. Krause M, <strong>Offermanns</strong> S, Stocker M, <strong>and</strong> Pedarzani P. Functional<br />

specificity of G alpha q <strong>and</strong> G alpha 11 in the cholinergic <strong>and</strong><br />

glutamatergic modulation of potassium currents <strong>and</strong> excitability in<br />

hippocampal neurons. J Neurosci 22: 666–673, 2002.<br />

351. Kreuzer J, Nurnberg B, <strong>and</strong> Krieger-Brauer HI. Lig<strong>and</strong>-dependent<br />

autophosphorylation of the insulin receptor is positively regulated<br />

by Gi-proteins. Biochem J 380: 831–836, 2004.<br />

352. Krispel CM, Chen CK, Simon MI, <strong>and</strong> Burns ME. Prolonged<br />

photoresponses <strong>and</strong> defective adaptation in rods of Gbeta5 �/�<br />

mice. J Neurosci 23: 6965–6971, 2003.<br />

353. Kuang Y, Wu Y, Jiang H, <strong>and</strong> Wu D. Selective G protein coupling<br />

by C-C chemokine receptors. J Biol Chem 271: 3975–3978, 1996.<br />

354. Kunapuli SP, Dorsam RT, Kim S, <strong>and</strong> Quinton TM. Platelet<br />

purinergic receptors. Curr Opin Pharmacol 3: 175–180, 2003.<br />

355. Kunkel EJ <strong>and</strong> Butcher EC. Chemokines <strong>and</strong> the tissue-specific<br />

migration of lymphocytes. Immunity 16: 1–4, 2002.<br />

356. Kurachi Y, Ito H, Sugimoto T, Katada T, <strong>and</strong> Ui M. Activation<br />

of atrial muscarinic K � channels by low concentrations of beta<br />

gamma subunits of rat brain G protein. Pflügers Arch 413: 325–327,<br />

1989.<br />

357. Kurihara Y, Kurihara H, Oda H, Maemura K, Nagai R,<br />

Ishikawa T, <strong>and</strong> Yazaki Y. Aortic arch malformations <strong>and</strong> ventricular<br />

septal defect in mice deficient in endothelin-1. J Clin Invest<br />

96: 293–300, 1995.<br />

358. Kurihara Y, Kurihara H, Suzuki H, Kodama T, Maemura K,<br />

Nagai R, Oda H, Kuwaki T, Cao WH, Kamada N, Jishage K,<br />

Ouchi Y, Azuma S, Toyoda Y, Ishikawa T, Kumada M, <strong>and</strong><br />

Yazaki Y. Elevated blood pressure <strong>and</strong> craniofacial abnormalities<br />

in mice deficient in endothelin-1 Nature 368: 703–710, 1994.<br />

359. Kurose H. Galpha12 <strong>and</strong> Galpha13 as key regulatory mediator in<br />

signal transduction. Life Sci 74: 155–161, 2003.<br />

360. Kuwahara K, Saito Y, Nakagawa O, Kishimoto I, Harada M,<br />

Ogawa E, Miyamoto Y, Hamanaka I, Kajiyama N, Takahashi N,<br />

Izumi T, Kawakami R, Tamura N, Ogawa Y, <strong>and</strong> Nakao K. The<br />

effects of the selective ROCK inhibitor, Y27632, on ET-1-induced<br />

hypertrophic response in neonatal rat cardiac myocytes—possible<br />

involvement of Rho/ROCK pathway in cardiac muscle cell hypertrophy.<br />

FEBS Lett 452: 314–318, 1999.<br />

361. Lambright DG. Heterotrimeric G protein signaling at atomic resolution.<br />

In: H<strong>and</strong>book of Cell Signaling, edited by Bradshaw RA<br />

<strong>and</strong> Dennis EA. Boston, MA: Academic, 2004, p. 575–5579.<br />

362. LaMorte VJ, Thorburn J, Absher D, Spiegel A, Brown JH,<br />

Chien KR, Feramisco JR, <strong>and</strong> Knowlton KU. Gq- <strong>and</strong> ras-dependent<br />

pathways mediate hypertrophy of neonatal rat ventricular<br />

myocytes following alpha 1-adrenergic stimulation. J Biol Chem<br />

269: 13490–13496, 1994.<br />

363. L<strong>and</strong>is CA, Masters SB, Spada A, Pace AM, Bourne HR, <strong>and</strong><br />

Vallar L. GTPase inhibiting mutations activate the alpha chain of<br />

Gs <strong>and</strong> stimulate adenylyl cyclase in human pituitary tumours.<br />

Nature 340: 692–696, 1989.<br />

364. Lang J. Molecular mechanisms <strong>and</strong> regulation of insulin exocytosis<br />

as a paradigm of endocrine secretion. Eur J Biochem 259: 3–17,<br />

1999.<br />

365. Lang J, Nishimoto I, Okamoto T, Regazzi R, Kiraly C, Weller<br />

U, <strong>and</strong> Wollheim CB. Direct control of exocytosis by receptormediated<br />

activation of the heterotrimeric GTPases Gi <strong>and</strong> G(o) or<br />

by the expression of their active G alpha subunits. EMBO J 14:<br />

3635–3644, 1995.<br />

366. Lania A, Mantovani G, <strong>and</strong> Spada A. G protein mutations in<br />

endocrine diseases. Eur J Endocrinol 145: 543–559, 2001.<br />

367. Laudanna C, Campbell JJ, <strong>and</strong> Butcher EC. Role of Rho in<br />

chemoattractant-activated leukocyte adhesion through integrins.<br />

Science 271: 981–983, 1996.<br />

368. Laugwitz KL, Allgeier A, <strong>Offermanns</strong> S, Spicher K, Van S<strong>and</strong>e<br />

J, Dumont JE, <strong>and</strong> Schultz G. The human thyrotropin receptor:<br />

a heptahelical receptor capable of stimulating members of all four<br />

G protein families. Proc Natl Acad Sci USA 93: 116–120, 1996.

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