24.12.2012 Views

Nina Wettschureck and Stefan Offermanns - Physiological Reviews

Nina Wettschureck and Stefan Offermanns - Physiological Reviews

Nina Wettschureck and Stefan Offermanns - Physiological Reviews

SHOW MORE
SHOW LESS

Create successful ePaper yourself

Turn your PDF publications into a flip-book with our unique Google optimized e-Paper software.

1192 NINA WETTSCHURECK AND STEFAN OFFERMANNS<br />

248. He W, Miao FJ, Lin DC, Schw<strong>and</strong>ner RT, Wang Z, Gao J, Chen<br />

JL, Tian H, <strong>and</strong> Ling L. Citric acid cycle intermediates as lig<strong>and</strong>s<br />

for orphan G protein-coupled receptors. Nature 429: 188–193, 2004.<br />

249. He W, Yasumatsu K, Varadarajan V, Yamada A, Lem J, Ninomiya<br />

Y, Margolskee RF, <strong>and</strong> Damak S. Umami taste responses<br />

are mediated by alpha-transducin <strong>and</strong> alpha-gustducin.<br />

J Neurosci 24: 7674–7680, 2004.<br />

250. Heasley LE. Autocrine <strong>and</strong> paracrine signaling through neuropeptide<br />

receptors in human cancer. Oncogene 20: 1563–1569, 2001.<br />

251. Hechler B, Leon C, Vial C, Vigne P, Frelin C, Cazenave JP, <strong>and</strong><br />

Gachet C. The P2Y1 receptor is necessary for adenosine 5’-diphosphate-induced<br />

platelet aggregation. Blood 92: 152–159, 1998.<br />

252. Hein L. Alpha-adrenergic system. In: Encyclopedic Reference of<br />

Molecular Pharmacology, edited by <strong>Offermanns</strong> S <strong>and</strong> Rosenthal<br />

W. Berlin: Springer, 2004, p. 27–30.<br />

253. Hendry IA, Kelleher KL, Bartlett SE, Leck KJ, Reynolds AJ,<br />

Heydon K, Mellick A, Megirian D, <strong>and</strong> Matthaei KI. Hypertolerance<br />

to morphine in G(z alpha)-deficient mice. Brain Res 870:<br />

10–19, 2000.<br />

254. Henquin JC, Garcia MC, Bozem M, Hermans MP, <strong>and</strong> Nenquin<br />

M. Muscarinic control of pancreatic B cell function involves sodium-dependent<br />

depolarization <strong>and</strong> calcium influx. Endocrinology<br />

122: 2134–2142, 1988.<br />

255. Hepler JR <strong>and</strong> Gilman AG. G proteins. Trends Biochem Sci 17:<br />

383–387, 1992.<br />

256. Hermosilla R. Vasopressin/oxytocin. In: Encyclopedic Reference<br />

of Molecular Pharmacology, edited by <strong>Offermanns</strong> S <strong>and</strong> Rosenthal<br />

W. Berlin: Springer, 2004, p. 957–961.<br />

257. Hersch E, Huang J, Grider JR, <strong>and</strong> Murthy KS. Gq/G13 signaling<br />

by ET-1 in smooth muscle: MYPT1 phosphorylation via ETA<br />

<strong>and</strong> CPI-17 dephosphorylation via ETB. Am J Physiol Cell Physiol<br />

287: C1209–C1218, 2004.<br />

258. Herve D, Le Moine C, Corvol JC, Belluscio L, Ledent C,<br />

Fienberg AA, Jaber M, Studler JM, <strong>and</strong> Girault JA. Galpha-<br />

(olf) levels are regulated by receptor usage <strong>and</strong> control dopamine<br />

<strong>and</strong> adenosine action in the striatum. J Neurosci 21: 4390–4399,<br />

2001.<br />

259. Heubach JF, Graf EM, Molenaar P, Jager A, Schroder F,<br />

Herzig S, Harding SE, <strong>and</strong> Ravens U. Murine ventricular L-type<br />

Ca(2�) current is enhanced by zinterol via beta(1)-adrenoceptors,<br />

<strong>and</strong> is reduced in TG4 mice overexpressing the human beta(2)adrenoceptor.<br />

Br J Pharmacol 133: 73–82, 2001.<br />

260. Heubach JF, Trebess I, Wettwer E, Himmel HM, Michel MC,<br />

Kaumann AJ, Koch WJ, Harding SE, <strong>and</strong> Ravens U. L-type<br />

calcium current <strong>and</strong> contractility in ventricular myocytes from<br />

mice overexpressing the cardiac beta 2-adrenoceptor. Cardiovasc<br />

Res 42: 173–182, 1999.<br />

261. Heximer SP, Knutsen RH, Sun X, Kaltenbronn KM, Rhee MH,<br />

Peng N, Oliveira-dos-Santos A, Penninger JM, Muslin AJ,<br />

Steinberg TH, Wyss JM, Mecham RP, <strong>and</strong> Blumer KJ. Hypertension<br />

<strong>and</strong> prolonged vasoconstrictor signaling in RGS2-deficient<br />

mice. J Clin Invest 111: 1259, 2003.<br />

262. Hill SJ <strong>and</strong> Baker JG. Histaminergic system. In: Encyclopedic<br />

Reference of Molecular Pharmacology, edited by <strong>Offermanns</strong> S <strong>and</strong><br />

Rosenthal W. Berlin: Springer, 2004, p. 456–460.<br />

263. Hillhouse EW, R<strong>and</strong>eva H, Ladds G, <strong>and</strong> Grammatopoulos D.<br />

Corticotropin-releasing hormone receptors. Biochem Soc Trans 30:<br />

428–432, 2002.<br />

264. Hines WA <strong>and</strong> Thorburn A. Ras <strong>and</strong> rho are required for Galphaqinduced<br />

hypertrophic gene expression in neonatal rat cardiac myocytes.<br />

J Mol Cell Cardiol 30: 485–494, 1998.<br />

265. Hirasawa A, Tsumaya K, Awaji T, Katsuma S, Adachi T,<br />

Yamada M, Sugimoto Y, Miyazaki S, <strong>and</strong> Tsujimoto G. Free<br />

fatty acids regulate gut incretin glucagon-like peptide-1 secretion<br />

through GPR120. Nat Med 11: 90–94, 2005.<br />

266. Hirsch E, Katanaev VL, Garl<strong>and</strong>a C, Azzolino O, Pirola L,<br />

Silengo L, Sozzani S, Mantovani A, Altruda F, <strong>and</strong> Wymann<br />

MP. Central role for G protein-coupled phosphoinositide 3-kinase<br />

gamma in inflammation. Science 287: 1049–1053, 2000.<br />

267. Ho MK <strong>and</strong> Wong YH. Structure <strong>and</strong> function of the pertussistoxin-insensitive<br />

Gz protein. Biol Signals Recept 7: 80–89, 1998.<br />

268. Hofer AM <strong>and</strong> Brown EM. Extracellular calcium sensing <strong>and</strong><br />

signalling. Nat Rev Mol Cell Biol 4: 530–538, 2003.<br />

Physiol Rev • VOL 85 • OCTOBER 2005 • www.prv.org<br />

269. Hofmann F. Smooth muscle tone regulation. In: Encyclopedic<br />

Reference of Molecular Pharmacology, edited by <strong>Offermanns</strong> S <strong>and</strong><br />

Rosenthal W. Heidelberg: Springer-Verlag, 2004, p. 870–875.<br />

270. Hofstetter HH, Shive CL, <strong>and</strong> Forsthuber TG. Pertussis toxin<br />

modulates the immune response to neuroantigens injected in incomplete<br />

Freund’s adjuvant: induction of Th1 cells <strong>and</strong> experimental<br />

autoimmune encephalomyelitis in the presence of high frequencies<br />

of Th2 cells. J Immunol 169: 117–125, 2002.<br />

271. Hollenberg MD <strong>and</strong> Compton SJ. International Union of Pharmacology.<br />

XXVIII. Proteinase-activated receptors. Pharmacol Rev<br />

54: 203–217, 2002.<br />

272. Hollinger S <strong>and</strong> Hepler JR. Cellular regulation of RGS proteins:<br />

modulators <strong>and</strong> integrators of G protein signaling. Pharmacol Rev<br />

54: 527–559, 2002.<br />

273. Hollopeter G, Jantzen HM, Vincent D, Li G, Engl<strong>and</strong> L, Ramakrishnan<br />

V, Yang RB, Nurden P, Nurden A, Julius D, <strong>and</strong><br />

Conley PB. Identification of the platelet ADP receptor targeted by<br />

antithrombotic drugs. Nature 409: 202–207, 2001.<br />

274. Holm C, Langin D, Manganiello V, Belfrage P, <strong>and</strong> Degerman<br />

E. Regulation of hormone-sensitive lipase activity in adipose tissue.<br />

Methods Enzymol 286: 45–67, 1997.<br />

275. Holz GG, Leech CA <strong>and</strong> Habener JF. Activation of a cAMPregulated<br />

Ca(2�)-signaling pathway in pancreatic beta-cells by the<br />

insulinotropic hormone glucagon-like peptide-1. J Biol Chem 270:<br />

17749–17757, 1995.<br />

276. Hooley R, Yu CY, Symons M, <strong>and</strong> Barber DL. G alpha 13<br />

stimulates Na � -H � exchange through distinct Cdc42-dependent<br />

<strong>and</strong> RhoA-dependent pathways. J Biol Chem 271: 6152–6158, 1996.<br />

277. Hornquist CE, Lu X, Rogers-Fani PM, Rudolph U, Shappell S,<br />

Birnbaumer L, <strong>and</strong> Harriman GR. G(alpha)i2-deficient mice with<br />

colitis exhibit a local increase in memory CD4� T cells <strong>and</strong> proinflammatory<br />

Th1-type cytokines. J Immunol 158: 1068–1077, 1997.<br />

278. Hoshijima M, Sah VP, Wang Y, Chien KR, <strong>and</strong> Brown JH. The<br />

low molecular weight GTPase Rho regulates myofibril formation<br />

<strong>and</strong> organization in neonatal rat ventricular myocytes. Involvement<br />

of Rho kinase. J Biol Chem 273: 7725–7730, 1998.<br />

279. Hou W, Wu Y, Sun S, Shi M, Sun Y, Yang C, Pei G, Gu Y, Zhong<br />

C, <strong>and</strong> Sun B. Pertussis toxin enhances Th1 responses by stimulation<br />

of dendritic cells. J Immunol 170: 1728–1736, 2003.<br />

280. Howlett AC, Barth F, Bonner TI, Cabral G, Casellas P, Devane<br />

WA, Felder CC, Herkenham M, Mackie K, Martin BR,<br />

Mechoulam R, <strong>and</strong> Pertwee RG. International Union of Pharmacology.<br />

XXVII. Classification of cannabinoid receptors. Pharmacol<br />

Rev 54: 161–202, 2002.<br />

281. Hoyer D, Clarke DE, Fozard JR, Hartig PR, Martin GR, Mylecharane<br />

EJ, Saxena PR, <strong>and</strong> Humphrey PP. International Union<br />

of Pharmacology classification of receptors for 5-hydroxytryptamine<br />

(serotonin). Pharmacol Rev 46: 157–203, 1994.<br />

282. Huang MC, Graeler M, Shankar G, Spencer J, <strong>and</strong> Goetzl EJ.<br />

Lysophospholipid mediators of immunity <strong>and</strong> neoplasia. Biochim<br />

Biophys Acta 1582: 161–167, 2002.<br />

283. Huang X, Ju Z, Song Y, Zhang H, Sun K, Lu H, Yang Z, Jose PA,<br />

Zhou G, Wang M, Wang W, Feng S, <strong>and</strong> Hui R. Lack of association<br />

between the G protein beta3 subunit gene <strong>and</strong> essential<br />

hypertension in Chinese: a case-control <strong>and</strong> a family-based study. J<br />

Mol Med 81: 729–735, 2003.<br />

284. Huang XP, Song X, Wang HY, <strong>and</strong> Malbon CC. Targeted expression<br />

of activated Q227L G(alpha)(s) in vivo. Am J Physiol Cell<br />

Physiol 283: C386–C395, 2002.<br />

285. Hunter JJ <strong>and</strong> Chien KR. Signaling pathways for cardiac hypertrophy<br />

<strong>and</strong> failure. N Engl J Med 341: 1276–1283, 1999.<br />

286. Hwang JI, Fraser ID, Choi S, Qin XF, <strong>and</strong> Simon MI. Analysis<br />

of C5a-mediated chemotaxis by lentiviral delivery of small interfering<br />

RNA. Proc Natl Acad Sci USA 101: 488–493, 2004.<br />

287. Iiri T, Herzmark P, Nakamoto JM, van Dop C, <strong>and</strong> Bourne HR.<br />

Rapid GDP release from Gs alpha in patients with gain <strong>and</strong> loss of<br />

endocrine function. Nature 371: 164–168, 1994.<br />

288. Ikeda SR. Voltage-dependent modulation of N-type calcium channels<br />

by G protein beta gamma subunits. Nature 380: 255–258, 1996.<br />

289. Imamura T, Ishibashi K, Dalle S, Ugi S, <strong>and</strong> Olefsky JM.<br />

Endothelin-1-induced GLUT4 translocation is mediated via Galpha(q/11)<br />

protein <strong>and</strong> phosphatidylinositol 3-kinase in 3T3-L1 adipocytes.<br />

J Biol Chem 274: 33691–33695, 1999.

Hooray! Your file is uploaded and ready to be published.

Saved successfully!

Ooh no, something went wrong!