Nina Wettschureck and Stefan Offermanns - Physiological Reviews

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1190 NINA WETTSCHURECK AND STEFAN OFFERMANNS 165. Esapa C, Foster S, Johnson S, Jameson JL, Kendall-Taylor P, and Harris PE. G protein and thyrotropin receptor mutations in thyroid neoplasia. J Clin Endocrinol Metab 82: 493–496, 1997. 166. Esposito G, Rapacciuolo A, Naga Prasad SV, Takaoka H, Thomas SA, Koch WJ, and Rockman HA. Genetic alterations that inhibit in vivo pressure-overload hypertrophy prevent cardiac dysfunction despite increased wall stress. Circulation 105: 85–92, 2002. 167. Exton JH. Mechanisms involved in alpha-adrenergic effects of catecholamines on liver metabolism. J Cyclic Nucleotide Res 5: 277–287, 1979. 168. Exton JH. Mechanisms of hormonal regulation of hepatic glucose metabolism. Diabetes Metab Rev 3: 163–183, 1987. 169. Exton JH. Regulation of phosphoinositide phospholipases by hormones, neurotransmitters, and other agonists linked to G proteins. Annu Rev Pharmacol Toxicol 36: 481–509, 1996. 170. Fabre JE, Nguyen M, Latour A, Keifer JA, Audoly LP, Coffman TM, and Koller BH. Decreased platelet aggregation, increased bleeding time and resistance to thromboembolism in P2Y1deficient mice. Nat Med 5: 1199–1202, 1999. 171. Farfel Z and Bourne HR. Pseudohypoparathyroidism: mutation affecting adenylate cyclase. Miner Electrolyte Metab 8: 227–236, 1982. 172. Farfel Z, Bourne HR, and Iiri T. The expanding spectrum of G protein diseases. N Engl J Med 340: 1012–1020, 1999. 173. Feighner SD, Tan CP, McKee KK, Palyha OC, Hreniuk DL, Pong SS, Austin CP, Figueroa D, MacNeil D, Cascieri MA, Nargund R, Bakshi R, Abramovitz M, Stocco R, Kargman S, O’Neill G, Van Der Ploeg LH, Evans J, Patchett AA, Smith RG, and Howard AD. Receptor for motilin identified in the human gastrointestinal system. Science 284: 2184–2188, 1999. 174. Feldman AM, Cates AE, Bristow MR, and Van Dop C. Altered expression of alpha-subunits of G proteins in failing human hearts. J Mol Cell Cardiol 21: 359–365, 1989. 175. Feuillan PP, Shawker T, Rose SR, Jones J, Jeevanram RK, and Nisula BC. Thyroid abnormalities in the McCune-Albright syndrome: ultrasonography and hormonal studies. J Clin Endocrinol Metab 71: 1596–1601, 1990. 176. Fields TA and Casey PJ. Signalling functions and biochemical properties of pertussis toxin-resistant G proteins. Biochem J 321: 561–571, 1997. 177. Filipek S, Stenkamp RE, Teller DC, and Palczewski K. G protein-coupled receptor rhodopsin: a prospectus. Annu Rev Physiol 65: 851–879, 2003. 178. Finch EA and Augustine GJ. Local calcium signalling by inositol- 1,4,5-trisphosphate in Purkinje cell dendrites. Nature 396: 753–756, 1998. 179. Finn SG, Plonk SG, and Fuller SJ. G alpha 13 stimulates gene expression and increases cell size in cultured neonatal rat ventricular myocytes. Cardiovasc Res 42: 140–148, 1999. 180. Foerster K, Groner F, Matthes J, Koch WJ, Birnbaumer L, and Herzig S. Cardioprotection specific for the G protein Gi2 in chronic adrenergic signaling through beta 2-adrenoceptors. Proc Natl Acad Sci USA 100: 14475–14480, 2003. 181. Foster CJ, Prosser DM, Agans JM, Zhai Y, Smith MD, Lachowicz JE, Zhang FL, Gustafson E, Monsma FJ Jr, Wiekowski MT, Abbondanzo SJ, Cook DN, Bayne ML, Lira SA, and Chintala MS. Molecular identification and characterization of the platelet ADP receptor targeted by thienopyridine antithrombotic drugs. J Clin Invest 107: 1591–1598, 2001. 182. Fragoso MC, Domenice S, Latronico AC, Martin RM, Pereira MA, Zerbini MC, Lucon AM, and Mendonca BB. Cushing’s syndrome secondary to adrenocorticotropin-independent macronodular adrenocortical hyperplasia due to activating mutations of GNAS1 gene. J Clin Endocrinol Metab 88: 2147–2151, 2003. 183. Fredholm BB, Abbracchio MP, Burnstock G, Dubyak GR, Harden TK, Jacobson KA, Schwabe U, and Williams M. Towards a revised nomenclature for P1 and P2 receptors. Trends Pharmacol Sci 18: 79–82, 1997. 184. Fredholm BB, APIJ, Jacobson KA, Klotz KN, and Linden J. International Union of Pharmacology. XXV. Nomenclature and classification of adenosine receptors. Pharmacol Rev 53: 527–552, 2001. Physiol Rev • VOL 85 • OCTOBER 2005 • www.prv.org 185. Fredriksson R, Lagerstrom MC, Lundin LG, and Schioth HB. The G protein-coupled receptors in the human genome form five main families. Phylogenetic analysis, paralogon groups, and fingerprints. Mol Pharmacol 63: 1256–1272, 2003. 186. Freeman ME, Kanyicska B, Lerant A, and Nagy G. Prolactin: structure, function, and regulation of secretion. Physiol Rev 80: 1523–1631, 2000. 187. Freissmuth M and Gilman AG. Mutations of GS alpha designed to alter the reactivity of the protein with bacterial toxins. Substitutions at ARG187 result in loss of GTPase activity. J Biol Chem 264: 21907–21914, 1989. 188. Freson K, Jaeken J, Van Helvoirt M, de Zegher F, Wittevrongel C, Thys C, Hoylaerts MF, Vermylen J, and Van Geet C. Functional polymorphisms in the paternally expressed XLalphas and its cofactor ALEX decrease their mutual interaction and enhance receptor-mediated cAMP formation. Hum Mol Genet 12: 1121–1130, 2003. 189. Freund TF, Katona I, and Piomelli D. Role of endogenous cannabinoids in synaptic signaling. Physiol Rev 83: 1017–1066, 2003. 190. Frey N, McKinsey TA, and Olson EN. Decoding calcium signals involved in cardiac growth and function. Nat Med 6: 1221–1227, 2000. 191. Frey N and Olson EN. Cardiac hypertrophy: the good, the bad, and the ugly. Annu Rev Physiol 65: 45–79, 2003. 192. Fritz G, Just I, and Kaina B. Rho GTPases are over-expressed in human tumors. Int J Cancer 81: 682–687, 1999. 193. Fromm C, Coso OA, Montaner S, Xu N, and Gutkind JS. The small GTP-binding protein Rho links G protein-coupled receptors and Galpha12 to the serum response element and to cellular transformation. Proc Natl Acad Sci USA 94: 10098–10103, 1997. 194. Fukuhara S, Chikumi H, and Gutkind JS. RGS-containing Rho- GEFs: the missing link between transforming G proteins and Rho? Oncogene 20: 1661–1668, 2001. 195. Fukuhara S, Murga C, Zohar M, Igishi T, and Gutkind JS. A novel PDZ domain containing guanine nucleotide exchange factor links heterotrimeric G proteins to Rho. J Biol Chem 274: 5868– 5879, 1999. 196. Funes S, Hedrick JA, Vassileva G, Markowitz L, Abbondanzo S, Golovko A, Yang S, Monsma FJ, and Gustafson EL. The KiSS-1 receptor GPR54 is essential for the development of the murine reproductive system. Biochem Biophys Res Commun 312: 1357–1363, 2003. 197. Gachet C. ADP receptors of platelets and their inhibition. Thromb Haemost 86: 222–232, 2001. 198. Galvin-Parton PA, Chen X, Moxham CM, and Malbon CC. Induction of Galphaq-specific antisense RNA in vivo causes increased body mass and hyperadiposity. J Biol Chem 272: 4335– 4341, 1997. 199. Gambaro G, Anglani F, and D’Angelo A. Association studies of genetic polymorphisms and complex disease. Lancet 355: 308–311, 2000. 200. Gamper N, Reznikov V, Yamada Y, Yang J, and Shapiro MS. Phosphatidylinositol 4,5-bisphosphate signals underlie receptorspecific Gq/11-mediated modulation of N-type Ca 2� channels. J Neurosci 24: 10980–10992, 2004. 201. Ganea D. Regulatory effects of vasoactive intestinal peptide on cytokine production in central and peripheral lymphoid organs. Adv Neuroimmunol 6: 61–74, 1996. 202. Garcia DE, Li B, Garcia-Ferreiro RE, Hernandez-Ochoa EO, Yan K, Gautam N, Catterall WA, Mackie K, and Hille B. G protein beta-subunit specificity in the fast membrane-delimited inhibition of Ca 2� channels. J Neurosci 18: 9163–9170, 1998. 203. Gardella TJ and Juppner H. Molecular properties of the PTH/ PTHrP receptor. Trends Endocrinol Metab 12: 210–217, 2001. 204. Gariepy CE. Intestinal motility disorders and development of the enteric nervous system. Pediatr Res 49: 605–613, 2001. 205. Gavett SH and Wills-Karp M. Elevated lung G protein levels and muscarinic receptor affinity in a mouse model of airway hyperreactivity. Am J Physiol Lung Cell Mol Physiol 265: L493–L500, 1993. 206. Gaylinn BD. Growth hormone releasing hormone receptor. Receptors Channels 8: 155–162, 2002.
207. Gehrmann J, Meister M, Maguire CT, Martins DC, Hammer PE, Neer EJ, Berul CI, and Mende U. Impaired parasympathetic heart rate control in mice with a reduction of functional G protein betagamma-subunits. Am J Physiol Heart Circ Physiol 282: H445– H456, 2002. 208. Gerard NP and Gerard C. Complement in allergy and asthma. Curr Opin Immunol 14: 705–708, 2002. 209. Germain-Lee EL, Ding CL, Deng Z, Crane JL, Saji M, Ringel MD, and Levine MA. Paternal imprinting of Galpha(s) in the human thyroid as the basis of TSH resistance in pseudohypoparathyroidism type 1a. Biochem Biophys Res Commun 296: 67–72, 2002. 210. Germain-Lee EL, Groman J, Crane JL, Jan de Beur SM, and Levine MA. Growth hormone deficiency in pseudohypoparathyroidism type 1a: another manifestation of multihormone resistance. J Clin Endocrinol Metab 88: 4059–4069, 2003. 211. Gershengorn MC and Osman R. Molecular and cellular biology of thyrotropin-releasing hormone receptors. Physiol Rev 76: 175– 191, 1996. 212. Gether U. Uncovering molecular mechanisms involved in activation of G protein-coupled receptors. Endocr Rev 21: 90–113, 2000. 213. Gether U, Asmar F, Meinild AK, and Rasmussen SG. Structural basis for activation of G protein-coupled receptors. Pharmacol Toxicol 91: 304–312, 2002. 214. Girkontaite I, Missy K, Sakk V, Harenberg A, Tedford K, Potzel T, Pfeffer K, and Fischer KD. Lsc is required for marginal zone B cells, regulation of lymphocyte motility and immune responses. Nat Immunol 2: 855–862, 2001. 215. Gohla A, Schultz G, and Offermanns S. Role for G(12)/G(13) in agonist-induced vascular smooth muscle cell contraction. Circ Res 87: 221–227, 2000. 216. Goldie RG, Henry PJ, Knott PG, Self GJ, Luttmann MA, and Hay DW. Endothelin-1 receptor density, distribution, and function in human isolated asthmatic airways. Am J Respir Crit Care Med 152: 1653–1658, 1995. 217. Goldman DW, Chang FH, Gifford LA, Goetzl EJ, and Bourne HR. Pertussis toxin inhibition of chemotactic factor-induced calcium mobilization and function in human polymorphonuclear leukocytes. J Exp Med 162: 145–156, 1985. 218. Goodman WG. Calcium-sensing receptors. Semin Nephrol 24: 17– 24, 2004. 219. Goren HJ, Northup JK, and Hollenberg MD. Action of insulin modulated by pertussis toxin in rat adipocytes. Can J Physiol Pharmacol 63: 1017–1022, 1985. 220. Gottsch ML, Cunningham MJ, Smith JT, Popa SM, Acohido BV, Crowley WF, Seminara S, Clifton DK, and Steiner RA. A role for kisspeptins in the regulation of gonadotropin secretion in the mouse. Endocrinology 145: 4073–4077, 2004. 221. Graler MH and Goetzl EJ. Lysophospholipids and their G protein-coupled receptors in inflammation and immunity. Biochim Biophys Acta 1582: 168–174, 2002. 222. Grandordy BM and Barnes PJ. Airway smooth muscle and disease workshop: phosphoinositide turnover. Am Rev Respir Dis 136: S17–S20, 1987. 223. Graziano MP and Gilman AG. Synthesis in Escherichia coli of GTPase-deficient mutants of Gs alpha. J Biol Chem 264: 15475– 15482, 1989. 224. Gregersen S, Thomsen JL, and Hermansen K. Endothelin-1 (ET-1)-potentiated insulin secretion: involvement of protein kinase C and the ET(A) receptor subtype. Metabolism 49: 264–269, 2000. 225. Greif GJ, Sodickson DL, Bean BP, Neer EJ, and Mende U. Altered regulation of potassium and calcium channels by GABA(B) and adenosine receptors in hippocampal neurons from mice lacking Galpha(o). J Neurophysiol 83: 1010–1018, 2000. 226. Griffin CT, Srinivasan Y, Zheng YW, Huang W, and Coughlin SR. A role for thrombin receptor signaling in endothelial cells during embryonic development. Science 293: 1666–1670, 2001. 227. Gross V, Tank J, Obst M, Plehm R, Blumer KJ, Diedrich A, Jordan J, and Luft FC. Autonomic nervous system and blood pressure regulation in RGS2-deficient mice. Am J Physiol Regul Integr Comp Physiol 288: R1134–R1142, 2005. CELLULAR FUNCTIONS OF G PROTEINS 1191 Physiol Rev • VOL 85 • OCTOBER 2005 • www.prv.org 228. Gu JL, Muller S, Mancino V, Offermanns S, and Simon MI. Interaction of G alpha(12) with G alpha(13) and G alpha(q) signaling pathways. Proc Natl Acad Sci USA 99: 9352–9357, 2002. 229. Gudermann T, Grosse R, and Schultz G. Contribution of receptor/G protein signaling to cell growth and transformation. Naunyn- Schmiedebergs Arch Pharmacol 361: 345–362, 2000. 230. Gutkind JS. Cell growth control by G protein-coupled receptors: from signal transduction to signal integration. Oncogene 17: 1331– 1342, 1998. 231. Gutkind JS, Novotny EA, Brann MR, and Robbins KC. Muscarinic acetylcholine receptor subtypes as agonist-dependent oncogenes. Proc Natl Acad Sci USA 88: 4703–4707, 1991. 232. Hall RA, Premont RT, Chow CW, Blitzer JT, Pitcher JA, Claing A, Stoffel RH, Barak LS, Shenolikar S, Weinman EJ, Grinstein S, and Lefkowitz RJ. The beta2-adrenergic receptor interacts with the Na � /H � -exchanger regulatory factor to control Na � /H � exchange. Nature 392: 626–630, 1998. 233. Hamm HE. The many faces of G protein signaling. J Biol Chem 273: 669–672, 1998. 234. Hampoelz B and Knoblich JA. Heterotrimeric G proteins: new tricks for an old dog. Cell 119: 453–456, 2004. 235. Harris IS, Treskov I, Rowley MW, Heximer S, Kaltenbronn K, Finck BN, Gross RW, Kelly DP, Blumer KJ, and Muslin AJ. G protein signaling participates in the development of diabetic cardiomyopathy. Diabetes 53: 3082–3090, 2004. 236. Hart MJ, Jiang X, Kozasa T, Roscoe W, Singer WD, Gilman AG, Sternweis PC, and Bollag G. Direct stimulation of the guanine nucleotide exchange activity of p115 RhoGEF by Galpha13. Science 280: 2112–2114, 1998. 237. Hartmann J, Blum R, Kovalchuk Y, Adelsberger H, Kuner R, Durand GM, Miyata M, Kano M, Offermanns S, and Konnerth A. Distinct roles of Galpha(q) and Galpha11 for Purkinje cell signaling and motor behavior. J Neurosci 24: 5119–5130, 2004. 238. Hata AN and Breyer RM. Pharmacology and signaling of prostaglandin receptors: multiple roles in inflammation and immune modulation. Pharmacol Ther 103: 147–166, 2004. 239. Hauger RL, Grigoriadis DE, Dallman MF, Plotsky PM, Vale WW, and Dautzenberg FM. International Union of Pharmacology. XXXVI. Current status of the nomenclature for receptors for corticotropin-releasing factor and their ligands. Pharmacol Rev 55: 21–26, 2003. 240. Hawkins D, Enyedi P, and Brown E. The effects of high extracellular Ca 2� and Mg 2� concentrations on the levels of inositol 1,3,4,5-tetrakisphosphate in bovine parathyroid cells. Endocrinology 124: 838–844, 1989. 241. Hay DW, Luttmann MA, Muccitelli RM, and Goldie RG. Endothelin receptors and calcium translocation pathways in human airways. Naunyn-Schmiedebergs Arch Pharmacol 359: 404–410, 1999. 242. Hayward BE, Barlier A, Korbonits M, Grossman AB, Jacquet P, Enjalbert A, and Bonthron DT. Imprinting of the G(s)alpha gene GNAS1 in the pathogenesis of acromegaly. J Clin Invest 107: R31–R36, 2001. 243. Hayward BE and Bonthron DT. An imprinted antisense transcript at the human GNAS1 locus. Hum Mol Genet 9: 835–841, 2000. 244. Hayward BE, Kamiya M, Strain L, Moran V, Campbell R, Hayashizaki Y, and Bonthron DT. The human GNAS1 gene is imprinted and encodes distinct paternally and biallelically expressed G proteins. Proc Natl Acad Sci USA 95: 10038–10043, 1998. 245. Hayward BE, Moran V, Strain L, and Bonthron DT. Bidirectional imprinting of a single gene: GNAS1 encodes maternally, paternally, and biallelically derived proteins. Proc Natl Acad Sci USA 95: 15475–15480, 1998. 246. He J, Gurunathan S, Iwasaki A, Ash-Shaheed B, and Kelsall BL. Primary role for G i protein signaling in the regulation of interleukin 12 production and the induction of T helper cell type 1 responses. J Exp Med 191: 1605–1610, 2000. 247. He W, Danilova V, Zou S, Hellekant G, Max M, Margolskee RF, and Damak S. Partial rescue of taste responses of alpha-gustducin null mice by transgenic expression of alpha-transducin. Chem Senses 27: 719–727, 2002.
Page 1 and 2: Mammalian G Proteins and Their Cell
Page 3 and 4: TABLE 1. Physiological ligands of G
Page 5 and 6: TABLE 1—Continued Sensory Stimuli
Page 7 and 8: FIG. 1. Functional cycle of G prote
Page 9 and 10: promoter driving the expression of
Page 11 and 12: FIG. 5.G q/G 11 family G proteins a
Page 13 and 14: G proteins, which mediate bronchoco
Page 15 and 16: lets under physiological and pathol
Page 17 and 18: to mediate these effects. The forme
Page 19 and 20: e attributed to an impaired lipolyt
Page 21 and 22: kocytes (56). Indirect evidence for
Page 23 and 24: A. Visual System The human retina c
Page 25 and 26: addressed the role of G proteins in
Page 27 and 28: C. G i-Mediated Cell Transformation
Page 29 and 30: 45. Berstein G, Blank JL, Jhon DY,
Page 31: 123. Cyster JG. Chemokines, sphingo
Page 35 and 36: 290. Imamura T, Vollenweider P, Ega
Page 37 and 38: 369. Laurent E, Mockel J, Van Sande
Page 39 and 40: Local calcium release in dendritic
Page 41 and 42: 533. Radu CG, Yang LV, Riedinger M,
Page 43 and 44: 616. Suwazono Y, Okubo Y, Kobayashi
Page 45 and 46: 695. Wu D, Huang CK, and Jiang H. R

Nina Wettschureck and Stefan Offermanns - Physiological Reviews

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