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Edinburgh, Scotland, United Kingdom - TAIR

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Pathogen effectors and host responses C25<br />

Thursday 14:30 - 15:00<br />

Plant Defence<br />

To enable a pathogenic lifestyle many organisms produce a repertoire of proteins<br />

that enable them to colonize host tissue. These proteins, effectors, are likely to<br />

be targeted to suppressing host immune mechanisms and redirecting nutritional<br />

resources to benefit the pathogen. We are studying the interaction between the<br />

downy mildew pathogen Hyaloperonospora arabidopsidis and Arabidopsis. We<br />

have just completed the sequencing of the H. arabidopsidis genome and it<br />

reveals a gene content that suggests that it has been adapted to a biotophic<br />

lifestyle. It has a very large effector content that suggests complex mechanisms<br />

of interaction between host and pathogen. We are analyzing the role of individual<br />

effector proteins in interacting with the host plant immune system. Finally, we<br />

are analyzing the role nature of the host plant response to biotic and abiotic<br />

stress using systems biology approaches.<br />

76<br />

Jim Beynon<br />

Warwick HRI<br />

University of Warwick<br />

Wellesbourne<br />

Warwick<br />

Warwickshire<br />

CV35 9EF

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