Edinburgh, Scotland, United Kingdom - TAIR

One genome is not enough: Genome-species
genome variation in Arabidopsis thaliana
Genome-wide sequence variation among populations reveals the history of
evolutionary processes and ecological forces that molded species. In the “postgenomic”
era, sequencing multiple natural strains from diverse populations has
becoming increasingly desirable in a broad areas such as evolutionary,
ecological and systems biology. As part of the 1001 genome project
(http://1001genomes.org), which aims to sequence at least 1001 strains of
Arabidopsis thaliana, we have completed a first pilot project, with 80 natural
strains from across Eurasia. Each strain was sequenced to 5- to 12-fold genome
coverage using Illumina’s sequencing-by-synthesis (SBS) technology. A
comprehensive inventory of sequence variation including single-nucleotide
polymorphisms (SNPs), small insertions/deletions (INDELs) and structural
variation were generated. The effects, patterns and distribution of sequence
variation have been analyzed and their population genetic implications will be
discussed.
66
C15
Wednesday 17:15 -17:30
Tools and Resources
Jun Cao1
Korbinian Schneeberger1
Stephan Ossowski1
Felix Ott1
Christa Lanz1
Carlos Alonso-Blanco2
Karl Schmid3
Detlef Weigel1
1Max Planck Institute for
Developmental Biology
Tübingen
Germany
2Centro Nacional de
Biotecnología (CNB-CSIC)
Madrid
Spain
3Institute of Plant Breeding
Seed Science and
Population Genetics
University of Hohenheim
Stuttgart
Germany