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Edinburgh, Scotland, United Kingdom - TAIR

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ABA and G-protein signaling in Arabidopsis<br />

guard cells<br />

Regulation of stomatal apertures by the phytohormone abscisic acid (ABA)<br />

promotes plant water conservation under drought conditions. ABA induces<br />

stomatal closure via an intricate cellular signaling network. We have applied<br />

systems biology methods to model this process (Li et al, PLoS Biology, 2006),<br />

and have recently characterized the Arabidopsis guard cell proteome with the<br />

goal of identifying new candidate stomatal signaling proteins (Zhao et al, Plant<br />

Cell, 2008). Heterotrimeric G proteins, composed of alpha, beta, and gamma<br />

subunits, are important secondary messengers in ABA signaling (e.g. Fan et al,<br />

PNAS, 2008). Most recently, we have identified two new ABA receptors that<br />

exhibit attributes of both G-protein-coupled receptors (GPCRs) and classic<br />

G-protein alpha subunits (Pandey et al, Cell, 2009). The biochemical and<br />

molecular genetic characterization of these proteins will be described.<br />

33<br />

L08<br />

Thursday 09:30 - 10:00<br />

Environmental Responses<br />

Sarah Assmann<br />

Biology Department<br />

Penn State University<br />

University Park<br />

PA<br />

16802<br />

USA

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