Thoracic Imaging 2003 - Society of Thoracic Radiology
Thoracic Imaging 2003 - Society of Thoracic Radiology
Thoracic Imaging 2003 - Society of Thoracic Radiology
You also want an ePaper? Increase the reach of your titles
YUMPU automatically turns print PDFs into web optimized ePapers that Google loves.
WEDNESDAY<br />
220<br />
Therefore, radiologists should be familiar with both criteria and<br />
their role in oncologic imaging. A meta-analysis <strong>of</strong> the data in<br />
eight studies <strong>of</strong> different solid tumors where the two different<br />
criteria were separately applied and reanalyzed demonstrated<br />
generally good correlation in that unidimensional measurement<br />
<strong>of</strong> maximal tumor diameter was felt to be sufficient to assess<br />
significant change in tumor size. 4 Similar results have been<br />
obtained in studies <strong>of</strong> lung cancer response where the unidimensional<br />
and bidimensional criteria were compared. 5,6 In these<br />
studies, there was generally good correlation between the final<br />
assessments, with a small number <strong>of</strong> differences noted in the<br />
some response categories. Interestingly, in the study by Werner-<br />
Wasik et al., which also included comparison with tumor volume,<br />
the validity <strong>of</strong> the RECIST criteria were confirmed and<br />
volume did not appear to represent a significantly superior<br />
method for evaluating tumor response.<br />
REFERENCES :<br />
1. Who handbook for reporting results <strong>of</strong> cancer treatment.<br />
Geneva (Switzerland): World Health Organization Offset<br />
Publication No. 48.; 1979.<br />
2. General forms and guidelines. In: Southwest Oncology Group<br />
Clinical Research Associate Manual. Vol. II; 2002.<br />
3. Therasse P, et al. New guidelines to evaluate the response to<br />
treatment in solid tumors. J Natl Cancer Inst; 92(3): 205-216.<br />
4. Eisenhauer JK, et al. Measuring response in solid tumors:<br />
unidimensional versus bidimensional measurement. J Natl<br />
Cancer Inst 1999;91(6):523-528.<br />
5. Cortes J, et al. Comparison <strong>of</strong> unidimensional and bidimensional<br />
measurements in metastatic non-small cell lung cancer.<br />
Br J Cancer 2002;87:158-160.<br />
6. Werner-Wasik M, et al. Assessment <strong>of</strong> lung cancer response<br />
after nonoperative therapy: tumor diameter, bidimensional<br />
product, and volume. A serial CT scan-based study. Int J<br />
Radiat Oncol Biol Phys 2001;51:56-61.