chapter 2 palladium catalysts in suzuki cross- coupling reaction
chapter 2 palladium catalysts in suzuki cross- coupling reaction
chapter 2 palladium catalysts in suzuki cross- coupling reaction
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3.2.2. Catalysts Anchored to Inorganic Solids.......................................... H31<br />
3.3. Zeolite supported <strong>palladium</strong> <strong>catalysts</strong> <strong>in</strong> the Suzuki Reactions............ H37<br />
3.3.1. Structural Features of Zeolite ......................................................... H37<br />
3.3.2. The Advantages of Zeolites ............................................................ H38<br />
3.3.3. Preparation of Zeolite-Supported Metal Catalysts.......................... H41<br />
CHAPTER 4. EXPERIMENTAL STUDY ...................................................................... H43<br />
4.1. Palladium-Loaded Zeolite Catalyst Preparation ................................... H43<br />
4.1.1. Palladium-Loaded Zeolite Catalyst Characterization ..................... H44<br />
4.2. General Procedures for the Suzuki Coupl<strong>in</strong>g Reactions....................... H44<br />
4.3. Characterization of Products................................................................. H45<br />
4.3.1. GC Method ..................................................................................... H45<br />
4.3.1.1. Calculation of Reactant and Product Amount on GC............ H46<br />
4.3.1.2. Calculation of Reactant Conversion, Product Yield and<br />
Recovery ................................................................................. H47<br />
4.4. Purification of the Products .................................................................. H48<br />
4.5. Leach<strong>in</strong>g Test........................................................................................ 52<br />
CHAPTER 5. RESULTS AND DISCUSSIONS ............................................................. 53<br />
5.1. The Suzuki Reactions of Aryl Chlorides .............................................. 53<br />
5.1.1. Pd-NaY Catalyzed Suzuki Reaction of 4-Chloroacetophenone<br />
with Phenylboronic Acid ................................................................. 53<br />
5.1.2. Pd(NH3)4 2+ -loaded NaY type Zeolite Catalyzed Suzuki Cross-<br />
Coupl<strong>in</strong>g Reaction of Aryl Chlorides .............................................. 60<br />
5.1.3. The Leach<strong>in</strong>g Test for Suzuki Reaction of Aryl Chlorides ............ 61<br />
5.2. The Suzuki Reactions of Aryl Bromides .............................................. 62<br />
5.2.1. The Optimization of Pd(NH3)4 2+ -Loaded NaY Type Zeolite<br />
Catalyzed Suzuki Reactions of 4-Bromoanisole with<br />
Phenylboronic Acid ......................................................................... 62<br />
5.2.2. Pd(NH3)4 2+ -Loaded NaY Type Zeolite Catalyzed Suzuki<br />
Reactions of Aryl Bromides and ArylBoronic Acids ...................... 65<br />
5.2.3. The Leach<strong>in</strong>g Test for the Suzuki Reactions of Aryl Bromides..... 68<br />
CHAPTER 6. CONCLUSIONS ....................................................................................... 69<br />
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