Cell Adhesion PCR Array Assay

Cell Adhesion PCR Array Assay
• Cells can adhere to other cells or to the extracellular matrix (ECM) by cell
junctions which are subcellular macromolecular structures and regulate many
important biological processes. There are several types of cell junctions
including tight junctions, adherent junctions, gap junctions, focal adhesion,
hemidesmosomes and desmosomes. Cell junctions play a specific role in cell
adhesion and transduction of mechanical force. A lot of pathophysiology of
diseases such as cancer metastasis, developmental abnormalities,
cardiovascular diseases and neurological disorders appear the destabilization
of cell junction integrity and function via gene expression changes or gene
mutations. To detect the gene expression changes and gene mutations of cell
junctions, profiler PCR array system has been applied, which combines the
quantitative performance of PCR with the multiple gene profiling of
microarrays.

• The Extracellular Matrix and Adhesion Molecules PCR Arrays are
widely used to profile dozens of genes involved in cell-cell and cellmatrix
adhesion simultaneously. It is useful to get meaningful data on
the adhesion molecule gene expression by the adhesion molecules
PCR arrays and these adhesion molecules include laminins, collagens
and other basement membrane molecules. These PCR arrays also
enable quick and reliable pathways analysis of adhesion molecule
gene expression. This method can save much time which is spent at
the bench and ensure a successful experiment every time. The
application specialists in our team are available to provide the best
technique support for your research. Even we can modify the PCR
arrays to suit your unique needs and offer the data analysis according
to your requirement.

• In summary, the Extracellular Matrix and Adhesion Molecules PCR Arrays at Creative Proteomics
are powerful and convenient to study the multiple gene expression changes or gene mutations of
adhesion molecules simultaneously.
• The great advantages of the Extracellular Matrix and Adhesion Molecules PCR Arrays:
• Profile dozens of genes related to cell adhesion simultaneously
• Specialist-designed arrays to suit your unique needs
• Simple procedure enables the reliable and rapid measurement
• Laboratory-verified assays ensure successful experiments and eliminate tedious optimization
• Complimentary data analysis ensure the perfect results