3. FOOD ChEMISTRy & bIOTEChNOLOGy 3.1. Lectures
3. FOOD ChEMISTRy & bIOTEChNOLOGy 3.1. Lectures
3. FOOD ChEMISTRy & bIOTEChNOLOGy 3.1. Lectures
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Chem. Listy, 102, s265–s1311 (2008) Food Chemistry & Biotechnology<br />
Fig. 6. Comparison of measured overall dietary exposure doses<br />
of total mercury and levels measured in blood (point estimate)<br />
tor of possible exposure to MeHg in this case. Other groups<br />
of foods are not of so important for exposure of the Czech<br />
population.<br />
The estimate of the dietary exposure from the most<br />
significant samples (sea fish) show tends to increase. This<br />
tendency to increase may be due to the trend of growing<br />
consumption this commodity given by development of business<br />
and import from seaside countries. The monitoring also<br />
showed an increasing tendency for the dietary exposure to<br />
mercury which was in correspondence with the levels of mercury<br />
in human blood in the same period. In the Fig. 5. are<br />
included data found for adult. The same trend can be seen for<br />
children too.<br />
Conclusion<br />
The content of total mercury in the samples of the food<br />
basket of the Czech Republic has been monitored since 1994.<br />
Produced data enabled the calculation of both - the exposure<br />
dose coming from individual samples and the total dietary<br />
exposure dose. The average value of the total dietary exposure<br />
in the period 1994–2007 is 0.0126 μg kg –1 b.w. day –1 It<br />
represents 0.0882 μg kg –1 b.w. week –1 .<br />
In 1978 the FAO/WHO JECFA evaluated total mercury<br />
and set PTWI at 5 μg kg –1 b.w. week –1 from which<br />
MeHg should not be higher than <strong>3.</strong>3 μg kg –1 b.w. week –1 .<br />
US EPA defined RfD 0.1 μg kg –1 b.w. day –1 . PTWI set by<br />
FAO/WHO JECFA for MeHg was revised into 1,6 μg kg –1<br />
b.w. week –1 (ref .9,10,11 ) in June 200<strong>3.</strong> According to longitudinal<br />
monitoring results it was proved that average value of<br />
overall dietary exposure to total mercury has not been breaking<br />
toxicological reference points set by FAO/WHO JECFA<br />
or US EPA in none of different population groups in the<br />
Czech Republic. Potentially risky groups are children and<br />
pregnant women or nursing mothers due to highest sensitivity<br />
of embryo/neonates in combination with dietary habit<br />
involving highly contaminated kinds of fish (mainly predator<br />
fish meat). Therefore it is important regularly evaluate dietary<br />
habit of the Czech population, analyse possible food sources<br />
of (at least) total mercury and do relevant advices to consumers.<br />
We should not forget that hazard of mercury in fish is<br />
s779<br />
in unknown extent balanced by benefits of some important<br />
nutrients coming from that food sources.<br />
REFEREnCES<br />
1. Masazumi Harada, M.D., Ph.D.: Minamata Disease and<br />
the Mercury Pollution of the Globe, http://www.einap.<br />
org/envdis/Minamata.html#name.<br />
2. Ruprich J., řehůřková I., Dofková M., in: .Environmental<br />
Health Monitoring System in the Czech Republic<br />
(Denková P., Puklová V., ed.), chapter VII, p. 58. national<br />
Institute of Public Health, Prague 2004.<br />
<strong>3.</strong> Ruprich J.: The Health Risk Assesment of Dietary Exposure<br />
to Selected Chemical Substances in year 2002.<br />
national Institute of Public Health, Prague 200<strong>3.</strong><br />
4. Černoevičová, M., Kořiva, V., Ostý, V., Resová, D.,<br />
řehůřková, I., Walterová, D.: Food Basket – Czech<br />
Republic(Ruprich J., ed.), national Institute of Public<br />
Health 199<strong>3.</strong><br />
5. Ruprich J. a kol.: Individuální spotřeba potravin v ČR<br />
– národní studie SISP04, Státní zdravotní ústav, Centrum<br />
hygieny potravinových řetězců Brno, http://www.<br />
chpr.szu.cz/spotrebapotravin.htm.<br />
6. Zdravotní důsledky expozice lidského organismu toxickým<br />
látkám ze zevního prostředí (biologický monitoring),<br />
Odborná zpráva za rok 2005, SZÚ Praha, Ústředí<br />
monitoringu zdravotního stavu, June 2006, http://www.<br />
szu.cz/uploads/documents/chzp/biomonitoring/biologicky_monitoring_05.pdf.<br />
7. Zdravotní důsledky expozice lidského organismu toxickým<br />
látkám ze zevního prostředí (biologický monitoring),<br />
Odborná zpráva za období 1994–2004, Státní zdravotní<br />
ústav Praha, Praha, June 2005. http://www.szu.cz/uploads/documents/chzp/biomonitoring/biologicky_monitoring_94_04.pdf.<br />
8. řehůřková I., Ruprich J. a kol.: Dietární expozice rtuti<br />
populace ČR, Snížení PTWI pro methyl rtuť, Státní zdravotní<br />
ústav, Centrum hygieny potravinových řetězců ,<br />
Brno, www.chpr.szu.cz .<br />
9. Ruprich J., řehůřková I., Drápal J., Kozáková M.:<br />
Stanovisko vědeckého výboru pro potraviny ve věci:<br />
Methylrtuť v rybách a rybích výrobcích, Státní zdravotní<br />
ústav, Centrum hygieny potravinových řetězců Brno,<br />
2004, http://www.chpr.szu.cz/vedvybor/dokumenty/stanoviska/stan_2004_5_deklas_Hg_rev1.pdf.<br />
10. World Health Organization, Food and Agriculture of<br />
the United nations Organization: Joint FAO/WHO<br />
expert committee on food additives, Sixty-first meeting,<br />
Summary and conclusions, Rome, 10-19 June<br />
2003, ftp://ftp.fao.org/es/esn/jecfa/jecfa61sc.pdf, loaded<br />
May 19, 2008.<br />
11. Ruprich J. a kol.: Zdravotní důsledky zátěže lidského<br />
organizmu cizorodými látkami z potravinových řetězců<br />
v roce 2005, Odborná zpráva za rok 2005, Státní zdravotní<br />
ústav Praha, 2006, http://www.chpr.szu.cz/monitor/tds05c/tds05c.htm.